ライフサイエンスコーパス: diagnostic

1 roved the cost-effectiveness of tuberculosis diagnostics.

2 ther the technology has application in virus diagnostics.

3 that rely on enrichment, thereby expediting diagnostics.

4 uide therapy and, potentially, for molecular diagnostics.

5 evelopment of macromolecular therapeutics or diagnostics.

6 for the dissemination of diverse blood-based diagnostics.

7 were tested by immunodiffusion at MiraVista Diagnostics.

8 For diagnostic ability testing purposes, we also examined as

9 erating characteristic curves determined the diagnostic accuracy (area under the curve, AUC).

10 ticular contrast material appears to improve diagnostic accuracy compared with 1.5-T MR imaging with

11 Purpose To determine the diagnostic accuracy for clinically significant prostate

12 erase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumoni

13 flectance confocal microscopy (RCM) improves diagnostic accuracy for LM and LMM and can be used to de

14 Diagnostic accuracy for malignant neoplasms was highest

15 ls (mean, 34.7 ng/L) (P < .001) and had high diagnostic accuracy for patients with AD with dementia v

16 Conclusion FDG PET/CT has satisfactory diagnostic accuracy in the detection of abdominal LN met

17 e Aptima ZIKV assay detected ZIKV RNA with a diagnostic accuracy of 94.8% (95% confidence interval [C

18 We sought to evaluate the diagnostic accuracy of angiography by visual estimate an

19 Diagnostic accuracy of attenuation measurements and dual

20 The overall per-vessel diagnostic accuracy of FFR-CT was 81.9% (95% CI, 79.4%-8

21 A growing body of evidence has validated the diagnostic accuracy of FFRCT techniques compared with in

22 ty country of Swaziland, we investigated the diagnostic accuracy of histidine-rich protein 2-based RD

23 Diagnostic accuracy of imaging markers selected from a m

24 atic review and meta-analysis to clarify the diagnostic accuracy of intraoperative breast margin asse

25 r thyroid cancer in asymptomatic adults, the diagnostic accuracy of screening (including neck palpati

26 al flow reserve of 0.80 or less and relative diagnostic accuracy of SPECT, PET, and CCTA in detecting

27 ith chronic liver disease and to compare the diagnostic accuracy of the imaging parameters in staging

28 The improvement in image quality and diagnostic accuracy of the technique was assessed in sim

29 nstrated here is not sufficient to establish diagnostic accuracy of this technique, but motivates fur

30 docardial UV at normal BV sites improves the diagnostic accuracy resulting in identification of all e

31 t interpretability, effective dose (ED), and diagnostic accuracy were assessed at CT angiography and

32 s with or without meta-analyses, criteria of diagnostic accuracy, and evidence-based clinical guideli

33 if the variation in these factors influenced diagnostic accuracy.

34 Assessment of diagnostic accuracy.

35 CI FFR of 0.92 was found to have the highest diagnostic accuracy; however, the positive likelihood ra

36 conditions exist where CBCT imaging improves diagnostic acumen and subsequent treatment recommendatio

37 lfone, or a sulfonamide functionality formed diagnostic adducts that had lost a methanol molecule upo

38 ncRNA-based blood test may have utility as a diagnostic adjunct for identifying IPMNs and their patho

39 Based on available evidence, a working diagnostic algorithm is proposed that can be adapted to

40 A diagnostic algorithm should take into account the patter

41 mited resources and compromising advances in diagnostic and academic pathology.

42 Following a brief review of current diagnostic and management strategies, we discuss the can

43 he MR technique presented here provides both diagnostic and motion information that can be used to im

44 The design of diagnostic and preventive strategies have been prevented

45 nt knowledge about extracellular vesicles as diagnostic and prognostic biomarkers, as well as their p

46 sion tree (CART) analyses were performed for diagnostic and prognostic performances.

47 Participants were 18 years or older, had Diagnostic and Statistical Manual of Mental Disorders-5

48 on of intestinal melanoma metastases and the diagnostic and therapeutic dilemmas involved.

49 epatology to complement traditional means of diagnostic and therapeutic discovery.

50 arget these repetitive RNAs are required for diagnostic and therapeutic purposes.

51 ll surface proteins, which present promising diagnostic and therapeutic targets in PDAC.

52 tematic reviews that addressed screening and diagnostic and treatment approaches for OCD among adults

53 y of Kenyans actively sought care; improving diagnostic and treatment capacity in the formal and info

54 We investigated sequences of giardiasis diagnostic and treatment events using MarketScan, a larg

55 s (HC), were analyzed via singleplex allergy diagnostics and a newly established immunoblot diagnosti

56 with TB will require simpler, more sensitive diagnostics and broader strengthening of health systems.

57 h in personalized medicine but also accurate diagnostics and monitoring drug therapies, which are cri

58 be utilized as a valuable biomarker in early diagnostics and prognostication of these cancers.

59 h offer the potential for enabling precision diagnostics and prognostics, as well as targeted patient

60 reagents are widely used in basic research, diagnostics and separations and for clinical application

61 n in mammals could facilitate improvement of diagnostics and therapeutics for affected patients with

62 of data provides new opportunities to impact diagnostics and therapeutics.

63 rns has major potential to advance molecular diagnostics and underpin research investigations.

64 ithout negative implications for prognostic, diagnostic, and therapeutic options for cardiovascular d

65 s precise composite scores, accurate routine diagnostics, and applicability to next-generation clinic

66 ransfusion, cellular therapy and blood-based diagnostics, and could significantly improve the sensiti

67 endous importance in cell signaling, medical diagnostics, and therapeutics.

68 lopment of some new neglected disease drugs, diagnostics, and vaccines.

69 ingle-molecule assay can be highly useful in diagnostic applications using various specimens for neur

70 Potential diagnostic applications were demonstrated by measuring Z

71 l for RNA detection both in bacteria and for diagnostic applications.

72 s for novel approaches to pharmaceutical and diagnostic applications.

73 Thus, applying WES to the diagnostic approach in CAKUT provides opportunities for

74 After a review of the literature, while diagnostic aspects of intrabony and furcation defects ca

75 usly reported, as well as a highly sensitive diagnostic assay for the ultratrace quantitation of a ph

76 atments can be linked to the approval of new diagnostic assays used to measure efficacy or to predict

77 The cohort underwent diagnostic assessment for LVNC by 4 separate imaging cri

78 ronary artery calcification (CAC) may impair diagnostic assessment of coronary computed tomography an

79 g and osteoarthritis, and provides potential diagnostic biomarkers and therapeutic targets.

80 Data from new diagnostic biomarkers can be combined with the clinical

81 e, whether in delivering drugs or extracting diagnostic biomarkers from skin.

82 ll, and we are still searching for potential diagnostic biomarkers.

83 risk, established clinical risk factors, and diagnostic biomarkers.

84 rs, and therefore may function as a clinical diagnostic biophysical biomarker.

85 of DLBCL is as accurate as genotyping of the diagnostic biopsy to detect clonally represented somatic

86 many fields including food safety, clinical diagnostics, biosafety and biosecurity.

87 As expected, pre-diagnostic blood glucose levels were inversely related t

88 Such diagnostics can substantially reduce the development tim

89 The current gold standard, culture-based diagnostics, can provide clinicians with comprehensive d

90 susceptibility, but sub-Saharan Africa lacks diagnostic capacity and antimicrobial resistance surveil

91 ent impact was high if there was a change in diagnostic category, moderate if there was a change in m

92 ge of applications, including the classroom, diagnostic centres, and research labs.

93 ome GBS cases do not exhibit a high level of diagnostic certainty.

94 Pancreatitis remains a diagnostic challenge in patients with mild to moderate d

95 between venoms of different species can be a diagnostic challenge.

96 Most centres were able to provide diagnostic challenges to antibiotics [40/44 (91%]) and l

97 etic testing, which, in turn, has raised new diagnostic challenges.

98 was based on applying five strictly defined diagnostic characteristics (eccentric hilum, longitudina

99 ve aphasia (PPA) variants defined by current diagnostic classification.

100 e advance of approaches to prevent premature diagnostic closure.

101 stry, ascertained NHS cases using exhaustive diagnostic code searching (1992-2010, >2500 medical reco

102 ta, identifies such deaths by assigning them diagnostic codes corresponding to "legal intervention" i

103 ility while enhancing discrimination between diagnostic cohorts.

104 is morphologic PVN classification scheme for diagnostic communication, especially at the time of inde

105 t of high-attenuation areas by screening and diagnostic computed tomography may be warranted in at-ri

106 Diagnostic concordance was 89% (95% CI, 75%-97%; kappa =

107 Diagnostic confidence was rated on a scale of 1 to 10.

108 Preclinical multiparametric diagnostics could help discover clinically relevant biom

109 al amplification to establish a CRISPR-based diagnostic (CRISPR-Dx), providing rapid DNA or RNA detec

110 emphasise the importance of recognising its diagnostic criteria and biomarker, which would be of gre

111 We then designed provisional HRCT diagnostic criteria based on the results to rank the ris

112 We aimed to identify diagnostic criteria for cHP that reach consensus among i

113 ipants (68.4%) fulfilled epidemiological and diagnostic criteria for first-episode psychosis (34.0 ne

114 national panel of experts endorsed consensus diagnostic criteria of IOI.

115 ed AD and 2 versions of the UK Working Party Diagnostic Criteria.

116 Compared with diagnostic CT alone, addition of PET to diagnostic CT si

117 with diagnostic CT alone, addition of PET to diagnostic CT significantly increased sensitivity in bot

118 The individual partition probabilities and diagnostic density plots further allow for some quality

119 on of amplification methods in point-of-care diagnostic devices and devices to be used in resource-li

120 end = 0.002; Me-Can, P trend = 0.04) and pre-diagnostic diabetes (AMORIS, HR = 0.30, 95% CI 0.17 to 0

121 l was used to estimate, after accounting for diagnostic disagreement, the frequency of diagnostic pro

122 1.3%-6.7%), there was clinically meaningful diagnostic discordance, with the FFR from the pressure w

123 gomyelins, we relied upon the aforementioned diagnostic EIEIO fragment peaks to determine the relativ

124 guidelines and recommendations (15ng/mL) for diagnostic ERBB2 assays that in the future may help to m

125 Diagnostic evaluation of eosinophilic esophagitis (EoE)

126 ion not only on preconception counseling and diagnostic evaluation to determine maternal and fetal ri

127 rently available therapy and require further diagnostic evaluation.

128 PCR-CI was defined as molecular diagnostic evidence of influenza virus in pharyngeal spe

129 Serial imaging sessions with concurrent diagnostic examinations for ROP.

130 of cancers and impact next-generation cancer diagnostic exams.

131 et ADHD symptoms, the most common reason for diagnostic exclusion was symptoms or impairment occurrin

132 diagnostic work-up for CD according to their diagnostic facilities.

133 Diagnostic factors found to be most prognostic on initia

134 Paper-based microfluidic diagnostics first emerged in 2007 as a low-cost alternat

135 Of 2044 MR imaging studies in the diagnostic group, 1443 were classified as having low BPE

136 ndifference, are commonly cited to explain a diagnostic hallmark of autism: reduced attention to othe

137 Recently, emerging molecular diagnostics have met requirements for speed, low cost, a

138 in breast cancer, technology developments in diagnostic imaging and radiation therapy have elucidated

139 udy suggests applications for UNO peptide in diagnostic imaging and therapeutic targeting of MEMs in

140 ltiple sclerosis (MS), but the international diagnostic imaging criteria for MS are not necessarily h

141 The initial diagnostic imaging findings were concordant with the bio

142 al case adjudication was based on conclusive diagnostic imaging, autopsy, surgery, or 14-day follow-u

143 A IgG reactivity underwent evaluation of the diagnostic importance of serum anti-BP180 IgE.

144 e goal of improving accessibility to medical diagnostics in developing countries.

145 relative merits of 3 approaches to molecular diagnostics in hematologic malignancies: indication-spec

146 tment strategy by combining therapeutics and diagnostics in the same agent.

147 s, can provide clinicians with comprehensive diagnostic information including bacterial identity and

148 em has the potential of providing additional diagnostic information over the traditional US imaging a

149 sider CBCT imaging only when they expect the diagnostic information yielded will lead to better patie

150 a critical evaluation of the prognostic and diagnostic insights that this technology can provide.

151 er diagnosis was used for assessment of post-diagnostic intake (median time from diagnosis to the die

152 aggregation pathways are of therapeutic and diagnostic interest, but obtaining critical information

153 translating biomarker candidates to clinical diagnostics is less pronounced.

154 a modern approach combining therapeutics and diagnostics, is among the most promising concepts in nuc

155 ireview is to provide a single reference for diagnostic laboratories that summarizes new and revised

156 were included, of whom 102 were assigned to diagnostic laparoscopy and 99 to primary surgery.

157 s do not adhere to IDSA guidelines, delaying diagnostic LP and increasing costs.

158 are likely to arise from the introduction of diagnostic M. genitalium nucleic acid amplification test

159 By contrast to clinical diagnostic measures using EMGs, which are performed on q

160 A bivariate model for diagnostic meta-analysis was used to attain overall pool

161 DWI can be an effective diagnostic method for distinguishing between benign and

162 Consistent use of this robust diagnostic method would result in more clearly defined,

163 Even though all cancers, irrespective of diagnostic method, should be reported to the CR, the PLC

164 A sustained effort to develop and share diagnostic methods can support the societal goal of impr

165 etransplant cohorts, but use of more precise diagnostic methods is needed to better define epidemiolo

166 lack of adequate, accessible, and affordable diagnostic methods that can enable better targeting of i

167 There remains an urgent need for rapid diagnostic methods that can evaluate antibiotic resistan

168 innovative technologies into cost-effective diagnostic methods that can mitigate the potentially cat

169 comparison with results obtained by standard diagnostic methods.

170 RI of the prostate gland is a relatively new diagnostic modality which is gathering a growing interes

171 By extending this precision diagnostic model nationally, we strive to meld clinical

172 For the low versus high BPE groups at diagnostic MR imaging, biopsy recommendation rate was 32

173 pulse sequences, and MR-conditional needles, diagnostic MR neurography-guided GFN blocks were perform

174 Therapeutic and diagnostic multifunctional HNPs conjugated with anti-MG1

175 in 202 case subjects with RHD and identified diagnostic mutations in genes known to be associated wit

176 75% (95% CI: 71%, 80%), respectively, with a diagnostic odds ratio of 8 (95% CI: 3, 18) and only fair

177 nsitivity of 0.94, specificity of 0.71 and a diagnostic odds-ratio of 36.8.

178 in vivo relative thickening of the En/DM is diagnostic of graft rejection as measured by DMT and DRI

179 Although some gene rearrangements are diagnostic of particular sarcoma types, certain fusion p

180 biased discovery of novel markers to improve diagnostic or predictive accuracy.

181 ndergoing elective or urgent anaesthesia for diagnostic or surgical procedures.

182 our understanding of ABMR and be useful for diagnostic or therapeutic purposes.

183 ide range of fields, including point-of-care diagnostics or cellular in vivo biosensing when using ul

184 broadly applicable (e.g., as an analytical, diagnostic, or separation tool).

185 abels have excellent potential in biomedical diagnostics, particularly when high signal to noise and

186 itional diagnosis compared with the standard diagnostic pathway.

187 Purpose To evaluate the diagnostic performance and examination success rate of m

188 ther with physiotherapy assistance increased diagnostic performance by microscopy (OR 1.6, 95% CI 1.3

189 eripapillary 3D RNFL volume showed excellent diagnostic performance for detecting glaucoma.

190 CMRO2 showed the highest diagnostic performance for IDH gene mutation detection i

191 We compared the diagnostic performance of cFFR between patients receivin

192 To evaluate the diagnostic performance of shear wave arrival time contou

193 Backroung: To investigate the diagnostic performance of the elastography-based strain

194 INTERPRETATION: The diagnostic performance of the improved CSF RT-QuIC is su

195 We evaluated the diagnostic performance of the new Xpert MTB/RIF Ultra (X

196 state cancer, no difference was found in the diagnostic performance of the short MR imaging protocol

197 water-only imaging provide, in one sequence, diagnostic performance similar to that of the standard c

198 clinical point score was generated, and its diagnostic performance was assessed using internal and e

199 The VOS showed the highest diagnostic performance with a sensitivity of 0.94, speci

200 ging modalities were compared with regard to diagnostic performance.

201 Purpose To compare the diagnostic performances of contrast material-enhanced sp

202 the radioligand (18)F-PSMA-1007 for use as a diagnostic PET tracer in prestaging and monitoring of pr

203 Cellulose paper is an ideal diagnostic platform for low-cost, easily disposable and

204 In this paper, an innovative diagnostic platform is presented which provides automate

205 nt of these features are facilitated through diagnostic plots and summary statistics computed over re

206 lular vesicle-associated microRNAs and their diagnostic potential in plasma samples of patients suffe

207 ic method, CancerLocator, which exploits the diagnostic potential of cell-free DNA by determining not

208 corresponding control types, emphasizes the diagnostic potential of this approach as a screening tec

209 The IHC assay has clear diagnostic potential to identify patients with a CI defe

210 The smallest-size annulus may have the best diagnostic potential, partly owing to having no areas ex

211 the epigenome for the development of future diagnostics, preventive strategies, and therapy for card

212 These data suggest diagnostic, procedure, and therapeutic codes derived fro

213 Diagnostic procedures, treatment strategies, and their o

214 the intact lipid as well as highly specific diagnostic product ions that reveal both the acyl chain

215 or diagnostic disagreement, the frequency of diagnostic progression and reversal.

216 Medical imaging studies achieve a diagnostic purpose and should be governed by the highest

217 It may therefore be relevant for diagnostic purposes or therapeutic interventions of alle

218 natural and recombinant oleosins for allergy diagnostic purposes.

219 s PET/CT acquisition technique that combines diagnostic-quality CT in the essential portion of the fi

220 rading of external studies was improved when diagnostic quantification was performed (85% versus 69%;

221 ications for the planning of therapeutic and diagnostic radiation treatments to reduce the risk of ra

222 Most reports (96.8%) were for diagnostic radiopharmaceuticals.

223 neral clinical genetics setting, the current diagnostic rate is approximately 50%, but for those who

224 y to associate variants with human diseases, diagnostic rates and development of new therapies are st

225 ptibility testing, from loading of sample to diagnostic readout, is less than 30 min, which allows th

226 rgy is underdiagnosed because of the lack of diagnostic reagents.

227 Results Diagnostic reference ranges (SSDEs) were 1.8-3.9, 2.2-4.

228 Diagnostic reference ranges were developed after analysi

229 ppendicitis and 6-week clinical follow-up as diagnostic reference standards.

230 eum pratense molecules and investigating the diagnostic relevance of such molecules in childhood.

231 The diagnostic response to the 2014-15 Ebola epidemic, altho

232 Diagnostic reversal and progression were confirmed for b

233 At present, rapid molecular diagnostics (RMDs) that can identify this phenotype are

234 y period highlight the need for standardized diagnostic routines and a better follow-up for LNB patie

235 The location and number of non-diagnostic segments was determined.

236 7, miR-346 and miR-34a-5p in PBMNCs had high diagnostic sensitivity and specificity in the context of

237 Assaying for anti-BP180 IgE increased the diagnostic sensitivity by only 2.2% (1 of 46 serum sampl

238 At the optimal cutoff, the diagnostic sensitivity for fGADA was lower than tGADA at

239 In response to a need for better sepsis diagnostics, several new gene expression classifiers hav

240 articularly katG p.Ser315Thr, into molecular diagnostics should enable targeted treatment of patients

241 To enable low cost diagnostic solutions, we recently established a citrate-

242 ty for fGADA was lower than tGADA at similar diagnostic specificities.

243 The 98.5% diagnostic specificity and 92% sensitivity of CSF RT-QuI

244 ble, but the safety and efficiency of such a diagnostic strategy are currently unknown.

245 agnostics and a newly established immunoblot diagnostic system.

246 nologies as the material for fabricating POC diagnostic systems.

247 by a precision medicine approach, with rapid diagnostic techniques of both bacterial and host factors

248 nces in histologic, serologic, and molecular diagnostic techniques to produce a consensus-based repor

249 Finally, we discuss how modern detection and diagnostic technologies as well as information from pass

250 By allowing all the relevant diagnostic terms for anaphylaxis to be included into the

251 ite infection status (as assessed by a rapid diagnostic test [RDT]), which is available in recent hou

252 Immunofluorescence is a highly specific diagnostic test for PCD, and it improves the speed and a

253 me time, inexpensive and minimally invasive, diagnostic test is urgently required, not only to confir

254 roblem is that there is no sufficiently fast diagnostic test to guide correct antibiotic prescription

255 by real-time PCR and for malaria by a rapid diagnostic test.

256 n reaction testing for Zika virus as well as diagnostic testing for Dengue fever and West Nile virus.

257 y-three evidence-based recommendations about diagnostic testing for latent tuberculosis infection, pu

258 ore, a high index of suspicion combined with diagnostic testing is essential component of severe acut

259 Point-of-care (POC) diagnostic testing platforms are a growing sector of the

260 nd it improves the speed and availability of diagnostic testing.

261 eactive and highly sensitive influenza rapid diagnostic tests (IRDTs) are required.

262 pecific histidine-rich protein 2-based rapid diagnostic tests (RDTs) to evaluate suspected malaria in

263 27, 2014, who were tested with malaria rapid diagnostic tests (RDTs), and administered questionnaires

264 t motivates exploration of noninvasive rapid diagnostic tests (RDTs).

265 Diagnostic tests and prescribed therapies were also reco

266 Commercially available rapid diagnostic tests are based upon detection of the influen

267 Rapid diagnostic tests based on Plasmodium falciparum histidin

268 ood and Drug Administration clearance of new diagnostic tests by promoting research that might not ha

269 The most notable new diagnostic tests in DED are tear film osmolarity, inflam

270 There are many diagnostic tests that are employed in the serological di

271 aimed at the development of new and specific diagnostic tests.

272 lts CT-guided sampling was more likely to be diagnostic than ENB-guided biopsy (86.0% [129 of 150] vs

273 ak led to an explosion in the development of diagnostics that could be performed at or near the point

274 Rapid diagnostics that enable identification of infectious age

275 Culture-independent diagnostics, the use of sepsis prediction scores, judici

276 TILs could skew the results of prognostic or diagnostic TIL assays.

277 utron imaging is investigated as a real-time diagnostic tool for visualization and in-situ measuremen

278 cardiac imaging has expanded from a largely diagnostic tool to an adjunctive tool to guide intervent

279 her a population-level screening or clinical diagnostic tool, we believe this platform can transform

280 these associations in vivo will lead to new diagnostic tools for Alzheimer disease and better unders

281 e inflammatory pathways or to be employed as diagnostic tools with colorimetric readout.

282 Nanocarrier and diagnostic ultrasound are able to enhance the drug penet

283 BI-RADS 3, 4, or 5 masses assessed at diagnostic US with biopsy-proven histologic findings and

284 e pathobiology of cancer and other diseases, diagnostics using in vivo liquid biopsy, and drug delive

285 Purpose To compare the diagnostic utility of an investigational optoacoustic im

286 We assessed the diagnostic utility of skin surface temperature in differ

287 e performed a meta-analysis to examine miRNA diagnostic value for SZ and further validated the meta-a

288 reus, and P. jirovecii are unlikely to be of diagnostic value in clinical settings.

289 In this study, we investigated the diagnostic value of (18)F-FDG PET/CT in chronic Q fever

290 Several of these proteins showed high diagnostic values with maximum area under the receiver o

291 (ICT) BinaxNow S. pneumoniae test (composite diagnostic) was positive.

292 optical imaging designs that permit on-site diagnostics with a cost-effective mobile-phone-based mul

293 edicines and nanoprobes for chemotherapy and diagnostics with an emphasis on in vivo applications.

294 Participants were asked to apply the usual diagnostic work-up for CD according to their diagnostic

295 plete mitochondrial genome sequencing in the diagnostic work-up of patients with suspected mitochondr

296 timodality approach is increasingly used for diagnostic workup and supported by recent guidelines.

297 y, a suggested novel algorithm for p53-based diagnostic workup in AML is presented, aiming at facilit

298 have demonstrated promising results for the diagnostic workup of prostate cancer.

299 To determine the diagnostic yield and use of clinical exome sequencing in

300 el candidates and provide an overview of the diagnostic yield of exome sequencing in consanguineous f