ライフサイエンスコーパス: diagnostic marker

1 troke, and explore their utility as an early diagnostic marker.

2 ine the CD4/CD8 ratio, an important HIV/AIDS diagnostic marker.

3 offering a potential system for a biological diagnostic marker.

4 agnetic resonance (1H NMR) spectroscopy as a diagnostic marker.

5 AD state and the potential for utility as a diagnostic marker.

6 and might have clinical utility as an early diagnostic marker.

7 gs have been employed in therapeutics and as diagnostic markers.

8 itions that are dependent on combinations of diagnostic markers.

9 ions that can be exploited as therapeutic or diagnostic markers.

10 expression, indicating a need for definitive diagnostic markers.

11 of the disease and for their possible use as diagnostic markers.

12 small-molecule-mediated therapy, as well as diagnostic markers.

13 6, and mesothelin, suggest potential use as diagnostic markers.

14 ggesting a possible utility of these mAbs as diagnostic markers.

15 in the discovery of therapeutic targets and diagnostic markers.

16 ave potential in vaccine preparations and as diagnostic markers.

17 perception and provide additional potential diagnostic markers.

18 cancer types and may serve as prognostic and diagnostic markers.

19 ce changes, frequently missing early disease diagnostic markers.

20 ed in the circulation and can serve as novel diagnostic markers.

21 herapies and secreted proteins to be used as diagnostic markers, a cDNA library was generated from me

22 EBV copy number quantification is a useful diagnostic marker across the spectrum of EBV(+)diseases,

23 clinical features because the disorders lack diagnostic markers, although the International Headache

24 ty of oligodendrogliomas and considered as a diagnostic marker and a prognostic indicator.

25 t development and suggest its candidacy as a diagnostic marker and as a therapeutic target in endomet

26 from this study suggest ACKR3 to be a viable diagnostic marker and demonstrate the utility of radiola

27 The lack of a sensitive and specific early diagnostic marker and of alternative treatments are the

28 tivator inhibitor-1 (PAI-1) has emerged as a diagnostic marker and predictor of VOD in humans.

29 pi m 1-negative patients and thus provides a diagnostic marker and rationale for VIT treatment with H

30 his long noncoding RNA may serve as a useful diagnostic marker and therapeutic target for cutaneous s

31 suggest that galectin-3 may serve as both a diagnostic marker and therapeutic target for future dise

32 , and elevated p38gamma may serve as a novel diagnostic marker and therapeutic target for human colon

33 ndrial redox pathways but also a potentially diagnostic marker and therapeutic target in human gliobl

34 rowth and highlight its value as a potential diagnostic marker and therapeutic target.

35 t(1;19)-positive ALL, suggesting a role as a diagnostic marker and therapeutic target.

36 rmine the potential use of this protein as a diagnostic marker and to analyze NS1 secretion in relati

37 spZ is likely to have limited potential as a diagnostic marker and vaccine candidate for Lyme disease

38 rcinoma progression, which will unveil early diagnostic markers and direct development of individuali

39 To identify new diagnostic markers and drug targets for pancreatic cance

40 ified several genes that represent potential diagnostic markers and may play a role in the pathogenes

41 potentially useful as vaccine candidates or diagnostic markers and may provide insight into the host

42 croenvironment is an underexplored source of diagnostic markers and potential therapeutic targets for

43 Biochemical diagnostic markers and readouts offer a physiological co

44 These programmes present promising diagnostic markers and targets for cancer-specific thera

45 levant pathways, making them potential novel diagnostic markers and targets for therapy.

46 and the relationship between the kinetics of diagnostic markers and the outcome of antifungal therapy

47 ld pave the way for the development of novel diagnostic markers and therapeutic approaches.

48 ates for the development of drugs, vaccines, diagnostic markers and therapeutic proteins.

49 As such, our findings offer plausible diagnostic markers and therapeutic target in the Wnt sig

50 tic-based diagnosis and development of novel diagnostic markers and therapeutic targets aimed to prev

51 tial clinical impact on development of novel diagnostic markers and therapeutic targets for lung canc

52 iologic insights as well as to serve as both diagnostic markers and therapeutic targets for many diff

53 and hundreds of previously unknown potential diagnostic markers and therapeutic targets for this synd

54 Future studies will evaluate potential diagnostic markers and therapeutic targets identified du

55 provide for the opportunity to identify new diagnostic markers and therapeutic targets in patients w

56 action, including some that may be useful as diagnostic markers and therapeutic targets.

57 tanding of disease pathogenesis and identify diagnostic markers and therapeutic targets.

58 ible for Hodgkin's disease and develop novel diagnostic markers and therapies.

59 In our effort to find diagnostic markers and to develop therapeutic approaches

60 l heterogeneity of HCC, and the lack of good diagnostic markers and treatment strategies, has rendere

61 or the development of disease stage-specific diagnostic markers and treatments.

62 ne-associated proteins that may serve as new diagnostic markers and, more importantly, as second-gene

63 for identifying genes that may be useful as diagnostic markers and/or as therapeutic targets for inv

64 In the clinic, p63 is often used as a diagnostic marker, and further analysis of the function

65 of hypoxic response, which can be used as a diagnostic marker, and proposes G9a as a therapeutic tar

66 Research on prevalence, pathophysiology, diagnostic markers, and future treatments is necessary t

67 the search for broadly effective therapies, diagnostic markers, and neural/genetic correlates.

68 Although they may serve as diagnostic markers, and provide evidence that there is a

69 rays can be effectively used to identify new diagnostic markers, and that CD10 is a reliable marker f

70 d be useful for studying immunopathogenesis, diagnostic markers, and therapy of human AIP.

71 kers of disease, identification of molecular diagnostic markers, and validation of radiopharmaceutica

72 -derived epitope identified may be used as a diagnostic marker as well as an immune target for develo

73 R-derived peptides identified may be used as diagnostic markers as well as immune targets for develop

74 ercial ELISAs detect CWP1, which is a useful diagnostic marker because it is highly stable, is secret

75 The diagnostic marker BG was shown to have a higher sensitiv

76 g of pathophysiology and availability of new diagnostic markers, but also for future targeted therapi

77 elevated resistance yielding multiplicative diagnostic markers, co-screening of which can give high

78 gonine appears to hold the most promise as a diagnostic marker compound for neonatal cocaine exposure

79 The Diagnostic Marker Cooperative Study was a prospective, m

80 Within this genomic window, a diagnostic marker, D1Rat219, assigned 91% of rats to the

81 ind for fungi and could be easily applied to diagnostic marker development for other newly emergent p

82 set providing resources for phylogenetic and diagnostic marker development for this species.

83 ous potential of gene array technologies for diagnostic marker discovery.

84 lung NE tumors remains controversial and few diagnostic markers distinguish typical and atypical carc

85 Telomerase activity may thus provide a diagnostic marker distinguishing benign from malignant f

86 Clonal diagnostic markers (eg, unique T- or B-cell receptor rea

87 Few diagnostic markers exist, and the cell of origin for man

88 In vivo tau imaging may become a diagnostic marker for Alzheimer disease (AD) and provide

89 icits, may have clinical utility as an early diagnostic marker for Alzheimer's disease.

90 p63 appears to be a valuable diagnostic marker for anaplastic keratinocytes.

91 our data suggests that FAIM2 may be a useful diagnostic marker for atypical carcinoid.

92 MTA was a highly accurate diagnostic marker for autopsy confirmed Alzheimer's dise

93 promotes tumor metastasis and is an accurate diagnostic marker for bladder cancer.

94 rtant early event in tumor progression and a diagnostic marker for breast and colon cancer developmen

95 Mammaglobin, a promising diagnostic marker for breast cancer, forms a covalent co

96 s enzyme a potentially useful prognostic and diagnostic marker for cancer, as well as a new target fo

97 CpG dinucleotides, which provide a possible diagnostic marker for cancer.

98 alternative splicing may have potential as a diagnostic marker for cancer.

99 D-Arabinitol (DA) is a useful diagnostic marker for candidiasis in patients with neutr

100 ration of cardiac troponin I, an established diagnostic marker for cardiac damage, was reduced by 90%

101 onsidered to be a significant prognostic and diagnostic marker for cardiac dysfunction.

102 Chloride in sweat is an important diagnostic marker for cystic fibrosis (CF), but the impl

103 basis of these results, we have generated a diagnostic marker for DFTD and identify a suite of genes

104 atients, indicating that LOXL2 may be a good diagnostic marker for HCC patients.

105 est the possibility of using CD10/CALLA as a diagnostic marker for HCC, various intrahepatic tumors w

106 ha-Fetoprotein (AFP) is frequently used as a diagnostic marker for hepatocellular carcinoma (HCC).

107 an cancer cells and implicates serum KL as a diagnostic marker for HMGA1-positive carcinomas.

108 eripheral blood could potentially serve as a diagnostic marker for hosts that are likely to progress

109 jor impact on the utility of telomerase as a diagnostic marker for human malignancy.

110 n telomerase has been recognized as a unique diagnostic marker for human tumors and is potentially a

111 ted isoform of MIF; oxMIF is therefore a new diagnostic marker for inflammation and a relevant target

112 Circulating T cell MPs are a novel diagnostic marker for inflammatory liver diseases, and i

113 levels in patients have been suggested as a diagnostic marker for many types of cancers.

114 d macrophage-based assay is a potential good diagnostic marker for MAP persistent infections and pred

115 a(latent) T-cell infiltrates may be a useful diagnostic marker for metastable tolerance.

116 nation of human cardiac troponin I (cTnI), a diagnostic marker for myocardial infarction, at clinical

117 enic gene and could serve as a potential new diagnostic marker for nonalcoholic and alcoholic liver f

118 e progression and suggest it as an important diagnostic marker for noninvasive imaging of ACKR3-overe

119 trations as a novel risk factor and possible diagnostic marker for obesity-related malignancies, incl

120 se of strain-specific CSIs as a new class of diagnostic marker for pathogen detection.

121 levated pipecolic acid levels may serve as a diagnostic marker for patients with pyridoxine-dependent

122 AS mutational status should be utilized as a diagnostic marker for predicting that response to anti-E

123 Recent work has identified AMACR as a new diagnostic marker for prostate cancer (PCa).

124 ched in B7-H3 protein, a recently identified diagnostic marker for prostate cancer, and an abundance

125 cific antigen (PSA) expression, an important diagnostic marker for prostate cancer, whereas inhibitin

126 ive resistance to therapy and may serve as a diagnostic marker for refractory disease.

127 LKBH3 is an antitumor target and a potential diagnostic marker for several tumor types, including pro

128 ncers, and Plk1 has been proposed as a novel diagnostic marker for several tumors.

129 ds) DNA antibodies are not only an important diagnostic marker for SLE, but also play an important ro

130 versity and suitability of this protein as a diagnostic marker for species identification.

131 To accelerate its deployment, we developed a diagnostic marker for Sr13 The identification of Sr13 ex

132 trite into the CSF has the potential to be a diagnostic marker for systemic inflammation and sepsis.

133 al interaction in B-CLL, as well as a useful diagnostic marker for the differential diagnosis of smal

134 sts that telomerase activity may be a useful diagnostic marker for the disease.

135 ated [-2]pPSA may represent an important new diagnostic marker for the early detection of PCa.

136 on molecule (CAM), has been reported to be a diagnostic marker for the early detection of the metasta

137 that Atp6v0a2 could be potentially used as a diagnostic marker for the evaluation of male infertility

138 ed their clinical utilization as a surrogate diagnostic marker for the presence of active MMPs in gro

139 Cortisol is an important diagnostic marker for the production of steroid hormones

140 Serum transferrin is a diagnostic marker for these patients, but there are no c

141 2-ME may have utility as a plasma and urine diagnostic marker for this disease, and may also serve a

142 icted to SMZL, thus representing a potential diagnostic marker for this lymphoma type.

143 study was to develop an immunohistochemical diagnostic marker for this pathologic entity.

144 3,3',5-Triiodothyronine (T3) is an important diagnostic marker for thyroid function.

145 and also that it may prove to be a valuable diagnostic marker for undifferentiated NPC.

146 ene (TSG) methylation has been proposed as a diagnostic marker for urothelial cancer (UC).

147 out the utility of executive impairment as a diagnostic marker for vascular dementia.

148 xecutive dysfunction might serve as a useful diagnostic marker for vascular dementia.

149 The lack of reliable and objective diagnostic markers for AD hampers early disease detectio

150 rived imaging probes have great potential as diagnostic markers for Alzheimer's disease and related t

151 e of multiple viruses may prove to be useful diagnostic markers for colonies afflicted with CCD.

152 anisms of the autoimmune attack and possible diagnostic markers for development of SjS-associated dac

153 s can partially be attributed to the lack of diagnostic markers for different clinical states of the

154 ection, therefore, there is need to find new diagnostic markers for early infection detection and dis

155 y gynecologic cancer, in part due to lack of diagnostic markers for early-stage disease and cell mode

156 study has led to identification of promising diagnostic markers for gastric cancer and can benefit fu

157 tide polymorphisms (SNPs) are one of the key diagnostic markers for genetic disease, cancer progressi

158 risation and identification of more reliable diagnostic markers for HD-like syndromes progress over t

159 ovides potential new therapeutic targets and diagnostic markers for high-risk HPV infections.

160 s, some of which have translational value as diagnostic markers for human diseases.

161 , Trim29, and keratin 5 (K5), which serve as diagnostic markers for human lung SCCs.

162 ctive for responses to treatment but are not diagnostic markers for initial stage 1 to 3 GI-GVHD.

163 gene transcripts that can serve as important diagnostic markers for ischemic stroke.

164 vels of sIL-2Ralpha and sCD163 are promising diagnostic markers for macrophage activation syndrome.

165 orphology and protrusions termed "blebs" are diagnostic markers for many human afflictions including

166 to pathogen infection and are used as early diagnostic markers for many human diseases, including ca

167 The identification of diagnostic markers for novel pathogens presents several

168 as targets in the development of serum-based diagnostic markers for ovarian cancer.

169 ein in human cerebrospinal fluid are helpful diagnostic markers for Parkinson's disease, if variables

170 luids of PD will be useful in development of diagnostic markers for PD.

171 activities in body fluids are often used as diagnostic markers for physiological conditions and dise

172 Indeed, diagnostic markers for predicting the response to therap

173 d help evaluate such inhibitors and identify diagnostic markers for the misfolded forms identified he

174 NCA) directed against proteinase 3 (PR3) are diagnostic markers for the small vessel vasculitides Weg

175 Antibodies to actin have been proposed as diagnostic markers for type 1 autoimmune hepatitis.

176 They are also considered potential diagnostic markers for various health disorders, and int

177 ceptibility have been unknown, and lack of a diagnostic marker heralding brain injury has impeded int

178 have recently emerged as a valuable class of diagnostic markers; however, thus far, neither extracell

179 IF levels in the blood may have utility as a diagnostic marker in CCRC.

180 data show the importance of SRSF2mut as new diagnostic marker in CMML.

181 PCT has been studied as a diagnostic marker in differentiating bacterial pneumonia

182 diate protein kinase C theta (PKCtheta) is a diagnostic marker in GISTs, including those that lack KI

183 tor essential to pigmentation and a clinical diagnostic marker in human melanoma.

184 to confirm the utility of Lisch nodules as a diagnostic marker in older children and adults and seem

185 o-1 may be a therapeutic target as well as a diagnostic marker in ovarian cancer.

186 Thus, plasma miR-10b levels may serve as a diagnostic marker in PDAC, whereas intra-tumoral miR-10b

187 etes remission after RYGB and may serve as a diagnostic marker in preoperative patient assessment.

188 ing tumorigenesis; hence, they are used as a diagnostic marker in tumor pathology.

189 s with drugs, as well as for quantitation of diagnostic markers in biofluids.

190 expressed exosomal miRNAs as candidates for diagnostic markers in colon cancer patients.

191 h for the discovery of novel candidate stage-diagnostic markers in CSF from patients infected with Tr

192 e and weight changes are common but variable diagnostic markers in major depressive disorder: some de

193 tors and discuss the compelling need for new diagnostic markers in these two autoimmune demyelinating

194 phological examination and the expression of diagnostic markers in transgenic embryos suggested that

195 Alternative diagnostic markers, including antibody detection, have b

196 inguish APN from lower UTI and function as a diagnostic marker indicative of VUR compared to other co

197 ential triggering factor because no reliable diagnostic marker is available to confirm the diagnosis.

198 In addition, a rapid assay for a reliable diagnostic marker is key to the success of these efforts

199 success of these neuroimaging approaches as diagnostic markers is, however, intrinsically linked to

200 ing cancer mucins currently used as clinical diagnostic markers likely represent only the clearance-r

201 Availability of early diagnostic markers may allow prompt initiation of therap

202 When combined with conventional diagnostic markers, miR-125a-3p can improve the diagnost

203 gesting that it may be a novel prognostic or diagnostic marker (n=126).

204 -associated lipocalin (NGAL), which is a new diagnostic marker of acute kidney injury (AKI).

205 Thus, whether urine IL-18 is an early diagnostic marker of AKI was investigated.

206 Anti-PA IgG is an important diagnostic marker of anthrax, a predictor of serum anti-

207 TCF4 served as a faithful diagnostic marker of BPDCN, and its downregulation cause

208 Abnormal cardiolipin is a specific diagnostic marker of cardiomyopathies caused by TAZ muta

209 h has been evaluated in several studies as a diagnostic marker of cervical cancer.

210 2) improve the use of the BCR-ABL gene as a diagnostic marker of disease, and 3) inhibit the express

211 on, we discuss the use of fungal mannan as a diagnostic marker of fungal disease.

212 furcation arrow has limited usefulness as a diagnostic marker of furcation invasion.

213 r mesenchymal tumors, therefore serving as a diagnostic marker of GIST.

214 lations of cells and identifying a potential diagnostic marker of infection.

215 that methylation of TSHR may provide a novel diagnostic marker of malignancy and a basis for potentia

216 n (PSA), which is the clinically most useful diagnostic marker of malignant disease.

217 rmed phenotype and thus may offer a specific diagnostic marker of malignant disease.

218 Loss of cortical grey matter is a diagnostic marker of many neurodegenerative diseases, an

219 SYT-SSX fusion transcripts are a defining diagnostic marker of synovial sarcomas and may also yiel

220 CD137 is a novel diagnostic marker of these tumors and suggests a possibl

221 botic microangiopathy rather than a specific diagnostic marker of TTP.

222 gth (P<0.0001) suggesting its potential as a diagnostic marker of vascular aging.

223 eriod, suggesting that NS1 is a viable early diagnostic marker of WNV infection.

224 l fluid biomarkers are gaining acceptance as diagnostic markers of Alzheimer's disease, with a potent

225 alciparum-infected young African children as diagnostic markers of CM.

226 cted by immunoblot analysis and used both as diagnostic markers of disease and as indicators of the p

227 on is needed to develop better therapies and diagnostic markers of disease manifestation.

228 mmunohistochemical stains for LC3 and p62 as diagnostic markers of drug-induced autophagic vacuolar m

229 ng long non-coding RNAs (lncRNAs) may act as diagnostic markers of incidentally-detected cystic PDAC

230 differentially expressed and could serve as diagnostic markers of malignancy.

231 ECM1 and TMPRSS4 are excellent diagnostic markers of malignant thyroid nodules and may

232 differentially expressed and could serve as diagnostic markers of malignant thyroid nodules.

233 orts have been devoted to providing clinical diagnostic markers of myocardial infarction (MI), leadin

234 pancreatic cancers creating hope that better diagnostic markers of pancreatic cancer will be soon for

235 considerable interest in identifying better diagnostic markers of pancreatic neoplasia.

236 that cellular parameters may show promise as diagnostic markers of sepsis.

237 Anti-dsDNA Abs are specific diagnostic markers of systemic lupus erythematosus, and

238 of dermaseptin S3 with full activity, showed diagnostic markers of yeast apoptosis: the appearance of

239 mors and suggest that PIK3CA may be a useful diagnostic marker or a therapeutic target in these cance

240 olution and paves the way for setting up new diagnostic markers or therapeutic strategies.

241 in pancreatic tumors may eventually serve as diagnostic markers or therapeutic targets.

242 or different genes, which could provide new diagnostic markers or therapeutic targets.

243 fusion tensor imaging appears to have strong diagnostic marker potential for these diseases.

244 A new diagnostic marker product for ONOO(-)is reported.

245 ell defined redox chemistry that form highly diagnostic marker products upon reaction with superoxide

246 e the tumor microenvironment and may provide diagnostic markers specific for EBV and KSHV associated

247 in blood plasma and shows more promise as a diagnostic marker than the nonphosphorylated protein.

248 l bilirubin (T-Bil) is an important clinical diagnostic marker that is measured frequently by physici

249 monocytes is a highly sensitive and specific diagnostic marker that rapidly and accurately distinguis

250 specifically expressed in GIST, is used as a diagnostic marker to differentiate GIST from other sarco

251 tudy demonstrating that DNI can be used as a diagnostic marker to distinguish APN from lower UTI and

252 nce from benign gliomas prompts its use as a diagnostic marker to distinguish primary brain tumors of

253 The tr-NK-1R could prove useful as a diagnostic marker to identify patients at risk for neopl

254 these antigens could be valuable for use as diagnostic markers to distinguish BCG vaccination from l

255 e of SIN3B and its target genes as candidate diagnostic markers to distinguish indolent from aggressi

256 ribe an integrated approach for detection of diagnostic markers using in situ assembled optical diffr

257 ensitivity of the furcation arrow image as a diagnostic marker was 38.7%, and the specificity was 92.

258 irulence diversity of blast populations with diagnostic markers will aid disease management.