ライフサイエンスコーパス: dialdehyde

1 nol dialdehyde and an optically active BINOL dialdehyde.

2 pared to the detection limit of the starting dialdehyde.

3 activity lost in cytosol treated with NADPH dialdehyde.

4 dase assays was lost on treatment with NADPH dialdehyde.

5 bis(3-indenyl)methane and a dipyrrylmethane dialdehyde.

6 amethoxybenzophenone also afforded a related dialdehyde.

7 reacting it with the appropriate triamine or dialdehyde.

8 methyltransferase inhibitor adenosine-2',3'-dialdehyde.

9 idatively ring-opened to afford cyclopentane dialdehydes.

10 ialdehydes similarly reacted to give fulvene dialdehydes.

11 ,12-dialdehyde oxidation product (TBOH-11,12-dialdehyde; 1.0 mg) after irradiation of approximately 1

12 with TFA, "3 + 1" condensation with pyrrole dialdehyde 12 gave the fluoranthoporphyrins 13 in good o

13 The tetrakis (tetrahydrofuranyl) dialdehydes 14 and 19 are accessible by oxidative cleava

14 tion of tripyrrane 11 with acenaphthopyrrole dialdehyde 16 gave the mixed acenaphthofluoranthoporphyr

15 groups to give novel dicarboxylic acid 11 or dialdehyde 16 in practical yields.

16 Dialdehyde 16 shows fast self-exchange between two equiv

17 ormation the novel one-pot transformation of dialdehyde 24 to pentacyclic unsaturated amine 25.

18 Dialdehydes 3 and 16 were comparable on both counts.

19 synthesized in high yield from diamine 4 and dialdehyde 5.

20 Dialdehyde 7 has been synthesized, converted into a vari

21 for 24 or 72 h in the presence of adenosine dialdehyde, a potent methyltransferase inhibitor, a subs

22 on we cultured rat PC12 cells with adenosine dialdehyde (AdOx), a methyltransferase inhibitor that pr

23 ral transcription, we utilized adenosine-2,3-dialdehyde (AdOx), an adenosine analog and S-adenosylmet

24 cetylated prior to isolation while the gluco-dialdehyde afforded a mixture of three stereoisomers in

25 yrin in 50% yield, while furan and thiophene dialdehydes afforded the corresponding oxa- and thiasapp

26 TNF-alpha-induced IL-6 production, adenosine dialdehyde, an inhibitor of S-adenosylhomocysteine hydro

27 )- ion centers with appropriate amounts of a dialdehyde and a diamine to facilitate the [n]rotaxane f

28 sized starting from both an achiral biphenol dialdehyde and an optically active BINOL dialdehyde.

29 ation with authentic standards, are crocetin dialdehyde and crocetin, respectively.

30 methane, "3 + 1" condensation with a pyrrole dialdehyde and dehydrogenation of the phlorin intermedia

31 alene 2-boronic acid with 2-bromobenzene-1,3-dialdehyde and requires only three steps.

32 Dehydration to form both the dialdehyde and the monohydrate is both acid- and base-ca

33 e substrate symmetrically to produce a C(14) dialdehyde and two C(13) products, which vary depending

34 the 9,10 (9',10') positions to produce a C14 dialdehyde and two C13 cyclohexones that vary depending

35 The different behavior between dialdehydes and ketoaldehydes is suggested to be resulti

36 2',3'-dialdehyde derivative of NADPH (NADPH dialdehyde) and neutrophil cytosol.

37 DA; 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde), are believed to play a role in the preventi

38 e-containing fulvene gave good yields of the dialdehyde at -78 degrees C or -100 degrees C, but the f

39 valently cross-linked product by utilizing a dialdehyde-based cross-linker, 1.

40 ynthesized from simple aromatic triamine and dialdehyde building blocks by dynamic imine chemistry at

41 synthesized from O-alkylcalixarene mono- and dialdehydes by a two-step conversion to the correspondin

42 A series of dialdehyde compounds were synthesized and reacted with t

43 ns within a knottin monomer and reacted with dialdehyde-containing cross-linkers of different lengths

44 e studied the interactions between the 2',3'-dialdehyde derivative of NADPH (NADPH dialdehyde) and ne

45 te is thought to be an aliphatic C5 semi- or dialdehyde, e.g., glutaric dialdehyde (Km = 1 mM).

46 However, the thiophene-containing fulvene dialdehyde failed to give any of the anticipated macrocy

47 clitols, while bis-Wittig olefination of the dialdehyde followed by Grubb's(II)-catalyzed RCM deliver

48 condensation of tripyrranes with monocyclic dialdehydes, followed by an oxidation step.

49 Allylindation of the same dialdehyde gave rise to lactol 16, a reactivity pattern

50 However, furan and thiophene dialdehydes gave highly insoluble products that could no

51 Manno- and galacto-configured dialdehydes gave predominantly single inosose stereoisom

52 agent, Acetyl Yellow 9 (AY9), using glutaric dialdehyde (GDI) as a molecular tether.

53 y cross-linking the system with the glutaric dialdehyde (GDI)-modified CHIT.

54 tosan chains, and cross-linked with glutaric dialdehyde (GDI).

55 e (GDH) in the CNT-CHIT films using glutaric dialdehyde (GDI).

56 We show here that the small dialdehyde glyoxal can successfully replace PFA Despite

57 udies on the macrocyclization of alpha,omega-dialdehydes have revealed a strong dependence on ring si

58 lls with the methylation inhibitor adenosine dialdehyde, ICP27 export to the cytoplasm occurred earli

59 ldehyde-treated cytosol and bound [32P]NADPH dialdehyde in a specific fashion.

60 s the conversion of zeaxanthin into crocetin-dialdehyde in Crocus.

61 protection step, condensation with a pyrrole dialdehyde in TFA-CH(2)Cl(2) gave the azuliporphyrin sys

62 hoxyazulitripyrrane condensed with a pyrrole dialdehyde in the presence of TFA, followed by oxidation

63 Reaction with a pyrrole dialdehyde in the presence of TFA, followed by oxidation

64 angement proceeds through an unsaturated 1,4-dialdehyde intermediate.

65 here derives from a single, readily prepared dialdehyde intermediate.

66 to give the crucial neo-confused dipyrrolic dialdehyde intermediates.

67 apors using the sprayed-on phenylenevinylene dialdehydes is superb and allows the identification of d

68 hatic C5 semi- or dialdehyde, e.g., glutaric dialdehyde (Km = 1 mM).

69 The subcomponent self-assembly of a bent dialdehyde ligand and different cationic and anionic tem

70 s from a primary monoamine, Fe(II) ions, and dialdehyde ligand strands that differ in length and stru

71 es (SN) via the silylated amine and glutaric dialdehyde links.

72 acterized by reactive alpha,beta-unsaturated dialdehyde moieties, including the drimane sesquiterpene

73 Incorporation of a naphthalene-dialdehyde moiety into the delta antagonist, 6'-aminonal

74 NNA) that contains a fluorogenic naphthalene dialdehyde moiety to identify neighboring lysine and cys

75 atization of the latter with naphthalene-2,3-dialdehyde (NDA) and quantification by reverse-phase hig

76 r containing a basic solution of naphthalene dialdehyde (NDA) and taurine.

77 re encountered in the preparation of fulvene dialdehydes needed for the synthesis of novel porphyrin

78 ted glycolurils or a glycoluril dimer with a dialdehyde (o-phthalaldehyde) delivers S-shaped dimers a

79 On the other hand, dialdehyde obtained from the oxidation of 1,6-diol was f

80 droxy-TBOH; 0.7 mg), and a ring-opened 11,12-dialdehyde oxidation product (TBOH-11,12-dialdehyde; 1.0

81 lhomocysteine hydrolase inhibitor (adenosine dialdehyde) potentiated toxicity of the Ado/CF combinati

82 es were obtained by postfunctionalization of dialdehyde precursor 1 using Knoevenagel condensation.

83 y crystallography confirmed that the fulvene dialdehyde precursor does have the correct geometry to f

84 In the key transformation, a protected dialdehyde precursor undergoes a cascade reaction to ins

85 hat the conversion of zeaxanthin to crocetin dialdehyde proceeds via the C30 intermediate 3-OH-beta-a

86 A pyrrole dialdehyde reacted under these conditions to give sapphy

87 The furan-derived dialdehyde reacted with a dipyrrylmethane in the presenc

88 mily was purified from liver as an aflatoxin dialdehyde reductase AKR7A1.

89 thylamine (1) with formaldehyde and glutaric dialdehyde, respectively, afforded intermediates 2 and 6

90 zed by condensation of two triamines and two dialdehydes separately.

91 es in the presence of Bu(2)BOTf, and azulene dialdehydes similarly reacted to give fulvene dialdehyde

92 ed by the condensation of linear diamine and dialdehyde subcomponents around copper(I) templates in t

93 The condensation of linear diamine and dialdehyde subcomponents around copper(I) templates in t

94 This reaction has been extended to aromatic dialdehydes, such as terephthalic dicarboxaldehyde and i

95 addition reactions to the latent C(7)-C(11) dialdehyde synthon.

96 veloped based on the reaction of naphthalene dialdehyde, taurine, and cyanide, yielding a fluorescent

97 s with o-bromoaryl aldehydes to furnish aryl dialdehydes that are converted to larger polycyclic arom

98 tions or the methylation inhibitor adenosine dialdehyde, the interaction of ICP27 with SRPK1 and Aly/

99 macrocyclic products with furan or thiophene dialdehydes, they afforded tetraphenyl heterobenziporphy

100 acid-catalyzed condensations with a pyrrole dialdehyde to afford good yields of diphenylbenziporphyr

101 n, this was condensed with a dipyrrylmethane dialdehyde to afford the adj-difluoranthoporphyrin 18.

102 d benzitripyrrane was reacted with a pyrrole dialdehyde to give an aromatic hydroxyoxybenziporphyrin.

103 tection step, these condensed with a pyrrole dialdehyde to give the related azuliporphyrins in 45-51%

104 , Brilliant Blue G or periodate oxidized ATP dialdehyde to the site of ATP release in the anterior hy

105 h pyrrole, furan, thiophene, and selenophene dialdehydes to give unstable porphyrinoids that were fur

106 y able to restore the activity lost in NADPH dialdehyde-treated cytosol and bound [32P]NADPH dialdehy

107 proteins present in extracts from adenosine dialdehyde-treated RAT1 cells.

108 NADPH dialdehyde treatment of cytosol resulted in the loss of

109 e substituted azulenes can be converted into dialdehydes under Vilsmeier-Haack conditions, and these

110 benzoate), which was linked with benzene-1,4-dialdehyde using imine condensation reactions, typical o

111 carbocyclic sugars from carbohydrate-derived dialdehydes using organocatalysis has been developed.

112 In a model study, an azulenylmethylpyrrole dialdehyde was condensed with a dipyrrylmethane in the p

113 preference of one triamine for a particular dialdehyde was further probed by transforming a non-pref

114 C, and the required furan-containing fulvene dialdehyde was isolated in 46% yield.

115 McMurry coupling of the dialdehyde was successfully employed, for the first time

116 The dialdehydes were condensed with dipyrrylmethanes in TFA/

117 The dialdehydes were investigated with respect to their amin

118 Acid-catalyzed condensation of a pyrene dialdehyde with a tripyrrane, followed by oxidation with

119 Treatment of the pyrene dialdehyde with phenylmagnesium bromide generated a dica

120 t ICL formation involves condensation of the dialdehyde with the exocyclic amine.

121 MacDonald "2 + 2" condensation of the dialdehydes with a dipyrrylmethane afforded a dihydropor

122 d "2 + 2" condensation of three benzophenone dialdehydes with a dipyrrylmethane gave oxophlorin analo

123 Reaction of dialdehydes with a known tetrapyrrole intermediate 11b i

124 Pyrrole dialdehydes with fused phenanthrene or acenaphthylene ri

125 he unusual reactivity of carborane mono- and dialdehydes with pyrroles in the presence of acid cataly

126 nvolved carrying out the condensation of the dialdehydes with the tetrapyrrole in TFA-dichloromethane

127 Both dialdehydes yield on reaction with OH- ions geminal diol