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2 enic nerve stimulation method allowing early diaphragmatic activation even in deep sedation and, 2) m
3 laryngeal adductor, laryngeal abductor, and diaphragmatic activities, resulting in central apnea wit
13 e lower sternum in association with anterior diaphragmatic and ventral abdominal wall defects suggest
14 transcription factors involved in thoracic, diaphragmatic, and esophageal development or proteins in
16 Prolonged mechanical ventilation results in diaphragmatic atrophy and contractile dysfunction in ani
17 e apocynin-induced attenuation of MV-induced diaphragmatic atrophy and contractile dysfunction occurr
23 lation, pressure support ventilation-induced diaphragmatic atrophy and weakness are associated with b
24 18 hrs of mechanical ventilation results in diaphragmatic atrophy in both laboratory animals and hum
25 the antioxidant Trolox attenuates MV-induced diaphragmatic atrophy independent of alterations in Akt
26 We tested the hypothesis that MV-induced diaphragmatic atrophy is associated with a loss of myonu
27 thesized that mechanical ventilation-induced diaphragmatic atrophy is associated with decreased synth
28 indicate that mechanical ventilation-induced diaphragmatic atrophy is dependent on the activation of
29 revealed that mechanical ventilation-induced diaphragmatic atrophy is due to increased diaphragmatic
31 te the mechanisms responsible for MV-induced diaphragmatic atrophy, we tested the hypothesis that con
35 mechanical ventilation results in decreased diaphragmatic blood flow and induces an oxygen supply-de
36 when subjects inspired using a predominantly diaphragmatic breath at rest (DeltaP(GA) = > 5 cmH(2)O,
37 During the ensuing expiratory phase of a diaphragmatic breath, there was a large resurgence of fe
38 The pattern of modulation during ribcage and diaphragmatic breathing persisted during both mild (peak
41 mechanical ventilation-induced activation of diaphragmatic caspase-3 and inhibition of caspase-3 prev
43 d the capacity to contribute to cells in the diaphragmatic central tendon and lung mesenchyme, indica
46 the PN was paced at 60 beats per minute and diaphragmatic compound motor action potential (CMAP) amp
47 the right PN at 60 per minute and recording diaphragmatic compound motor action potential (CMAP) via
52 us between oxidative stress and the impaired diaphragmatic contractility that develops during MV.
53 ein-1, and tumor necrosis factor-alpha), and diaphragmatic contractility were evaluated after 24 hour
57 hypothesized the occurrence of an expiratory diaphragmatic contraction directed at stabilizing periph
58 ich transvenously stimulates a nerve causing diaphragmatic contraction similar to normal breathing.
60 afferent fibers was recorded during rhythmic diaphragmatic contractions before and after the onset of
61 rural diaphragm was recorded during rhythmic diaphragmatic contractions before the onset of and durin
63 ers discharged more (p<0.05) during rhythmic diaphragmatic contractions when the diaphragm was fatigu
66 sence or absence of PH near the level of the diaphragmatic crura was retrospectively established by a
69 ng single-gene knockout mice associated with diaphragmatic defects, rare monogenetic disorders in hum
71 defined as bulbar, upper limb, lower limb or diaphragmatic), diagnosis, functional involvement of a s
72 ry signal was compared with an MR measure of diaphragmatic displacement via a pencil-beam navigator.
73 and causes artifactual defects predicted by diaphragmatic displacement, body mass index, and heart s
77 henomenon, referred to as ventilator-induced diaphragmatic dysfunction (VIDD), is poorly understood.
78 ion support can attenuate ventilator-induced diaphragmatic dysfunction but corresponding human data a
80 insights into the role of open lung biopsy, diaphragmatic dysfunction, and a potential mechanism for
82 ls and humans can lead to ventilator-induced diaphragmatic dysfunction, which includes muscle atrophy
89 extent with lower lung volume, indicating a diaphragmatic electromechanical coupling during spontane
90 e superior vena cava, all patients underwent diaphragmatic electromyographic monitoring using surface
91 each) during incremental cycle exercise with diaphragmatic electromyography (EMGdi) and respiratory p
93 storation of RSA using an hCPG that receives diaphragmatic electromyography input and use it to stimu
94 ons increased respiratory frequency (fR) and diaphragmatic EMG (dEMG) amplitude in relation to the du
95 (2) was higher and intercostal, scalene, and diaphragmatic EMG activity was reduced using NIOV+O(2) c
98 The increase in spindle discharge during diaphragmatic fatigue is inconsistent with the notion th
100 is that MV is associated with atrophy of all diaphragmatic fiber types, increased diaphragmatic prote
103 ssisted mechanical ventilation will preserve diaphragmatic force and prevent overexpression of MAF-bo
105 y, administration of bortezomib improved the diaphragmatic force compared to mechanically ventilated
106 PD-associated diaphragm remodeling decreases diaphragmatic force generation by adaptations within eac
107 unit pressure, the inspiratory effect of the diaphragmatic force on the lower ribs is equal to the ex
109 function, and few techniques exist to assess diaphragmatic function: the purpose of this study was to
110 halocele (adjusted odds ratio (aOR) = 2.68), diaphragmatic hernia (aOR = 2.58), small intestinal atre
112 uman fetuses with severe isolated congenital diaphragmatic hernia (CDH) and changes in tracheal and a
130 on the highest risk patients with congenital diaphragmatic hernia (CDH), those with agenesis of the d
131 adily identifiable perinatally in congenital diaphragmatic hernia (CDH), where the typical pulmonary
133 used therapy among patients with congenital diaphragmatic hernia (CDH); however, data to support its
135 TM, n=15), tracheal occlusion for congenital diaphragmatic hernia (CDH, n=13), and resection of sacro
136 n and that had severe, left-sided congenital diaphragmatic hernia (liver herniation and a lung-to-hea
137 cholelithiasis (n=2), pyelonephritis (n=2), diaphragmatic hernia (n=1), cecal bascule (n=1), ileus (
138 , $111566 [IQR, $91195-$139936]), congenital diaphragmatic hernia (WIQR, $43948; median, $154730 [IQR
139 s those with sickle cell disease, congenital diaphragmatic hernia and Eisenmenger syndrome who may be
143 vomiting, diagnosed to have an incarcerated diaphragmatic hernia causing gastric pneumatosis and res
144 performed in prenatally diagnosed congenital diaphragmatic hernia infants (n = 171) born between Nove
149 cians who encounter children with congenital diaphragmatic hernia on either a regular or infrequent b
150 y clinician treating infants with congenital diaphragmatic hernia regarding the latest developments a
151 covered as an incidental finding, late-onset diaphragmatic hernia should be considered a surgical eme
152 ely collected patient data in the Congenital Diaphragmatic Hernia Study Group registry between Januar
153 oreal membrane oxygenation and/or congenital diaphragmatic hernia with an intelligence quotient great
154 all cases of isolated left-sided congenital diaphragmatic hernia without prenatal intervention (n =
155 hypoplasia, and the fetuses with congenital diaphragmatic hernia, at least a portion of the diaphrag
156 agenesis of the corpus callosum, congenital diaphragmatic hernia, facial dysmorphology, ocular anoma
157 -reduction defects, polydactyly, syndactyly, diaphragmatic hernia, heart defects overall, pulmonary-a
158 urysm, developmental emphysema, inguinal and diaphragmatic hernia, joint laxity, and pectus excavatum
159 wel perforation, bowel resection, congenital diaphragmatic hernia, oesophageal atresia, and ruptured
160 chial arch derivatives, heart malformations, diaphragmatic hernia, renal hypoplasia and ambiguous gen
161 girl 32 days after a repair of a congenital diaphragmatic hernia, with ultrasound signs of acute bow
173 ragm development are the cause of congenital diaphragmatic hernias (CDHs), a common and often lethal
174 hic lung-head ratio in left-sided congenital diaphragmatic hernias evaluated before 27 weeks gestatio
175 Sox7(Deltaex2/+) mice developed retrosternal diaphragmatic hernias located in the anterior muscular p
176 cts, renal agenesis and develop retrosternal diaphragmatic hernias which are covered by a membranous
177 ital anomalies, pyloric stenosis, congenital diaphragmatic hernias, cardiac septal defects, hearing l
178 gous for the dd allele possess communicating diaphragmatic hernias, central tendon patterning defects
179 efects in the heterozygotes included midline diaphragmatic hernias, dilated distal airways, and cardi
180 lities, these infertile males presented with diaphragmatic hernias, hemoperitoneum and many secondary
182 ion of the gastroesophageal junction and the diaphragmatic hiatus were 0.88 and 0.85, respectively.
183 lso indicate that differential regulation of diaphragmatic IGF-1-PI3K-Akt signalling exists during th
185 he combination of 18 to 69 hours of complete diaphragmatic inactivity and mechanical ventilation resu
186 n for 18 to 69 hours; among control subjects diaphragmatic inactivity and mechanical ventilation were
188 tly revealed that 18 to 69 hours of complete diaphragmatic inactivity associated with mechanical vent
189 versupply relative to demand, resulting from diaphragmatic inactivity during MV, could play an import
192 Twenty-seven patients had VCG evidence of diaphragmatic infarction; 25 of this group had severe na
198 ion may reduce the frequency and severity of diaphragmatic injury when adjacent liver is treated with
199 o retrospectively determine the frequency of diaphragmatic injury when percutaneous hepatic radiofreq
200 rs adjacent to the diaphragm, five (17%) had diaphragmatic injury, which was clinically apparent with
203 athing-which effectively pull in air-are the diaphragmatic, intercostal, spine, and neck muscles.
206 controlled ventilation, we assessed in vitro diaphragmatic isometric and isotonic contractile functio
207 ions with assisted mechanical ventilation on diaphragmatic isometric, isotonic contractile properties
208 ingly, independent of MV, apocynin increased diaphragmatic levels of calpastatin, an endogenous calpa
209 on with time-matched controls, did not alter diaphragmatic levels of Type I and IIx myosin heavy chai
211 velopment of new medicines that can maintain diaphragmatic mass and function during prolonged mechani
212 chanical ventilation (MV) results in reduced diaphragmatic maximal force production and diaphragmatic
214 mechanical ventilation-induced increases in diaphragmatic mitochondrial reactive oxygen species emis
216 was terminated on any perceived reduction in diaphragmatic motion or a 30% decrease in the compound m
217 ore marked in the 33 PVs with a reduction in diaphragmatic motion than in those without (40.9+/-15.3%
220 usions but also look at lung recruitment and diaphragmatic movement, hence can aid in deciding extuba
225 MV resulted in a decrease (p < 0.05) in diaphragmatic myofibrillar protein and the cross-section
227 emphysematous hamsters reflecting a greater diaphragmatic O2 utilization at rest and a lower O2 extr
228 Prolonged mechanical ventilation results in diaphragmatic oxidative injury, elevated proteolysis, fi
229 trophy and weakness are associated with both diaphragmatic oxidative stress and protease activation.
230 n mice, induction of hyperlipidemia worsened diaphragmatic oxidative stress during MV, whereas transg
232 late that this ventilator-induced decline in diaphragmatic oxygenation could promote a hypoxia-induce
233 gement including noninvasive ventilation and diaphragmatic pacing, secretions, nutrition, dysphagia a
234 A group of 13 patients with early onset diaphragmatic palsy in association with a progressive ne
239 y, pelvic, parietal anterior, left and right diaphragmatic peritonectomy), 14 visceral resections, 5
242 gmatic and esophageal pressure, twitch trans-diaphragmatic pressure (Tw Pdi), age, and maximal static
244 of all diaphragmatic fiber types, increased diaphragmatic protease activity, and augmented diaphragm
245 ed diaphragmatic atrophy is due to increased diaphragmatic protein breakdown and decreased protein sy
246 rther, MV promoted an increase (p < 0.05) in diaphragmatic protein degradation along with elevated (p
247 chain protein synthesis; this depression in diaphragmatic protein synthesis persisted throughout 18
248 ically ventilated for 6, 12, or 18 hours and diaphragmatic protein synthesis was measured in vivo.
249 s that controlled MV results in oxidation of diaphragmatic proteins and increased diaphragmatic prote
250 or regulating mechanical ventilation-induced diaphragmatic proteolysis and contractile dysfunction.
252 tion of diaphragmatic proteins and increased diaphragmatic proteolysis due to elevated protease activ
260 The knowledge of the CT findings suggesting diaphragmatic rupture improves the detection of injuries
268 nd 18PSV promoted a significant decrement in diaphragmatic specific force production, but to a lesser
269 8%), loss of left ventricular capture (10%), diaphragmatic stimulation (2%), loss of right ventricula
278 are abolished following either bilateral sub-diaphragmatic total truncal vagotomy or brainstem-hypoth
280 ntly increased above their basal levels, and diaphragmatic weakness and further increases in caspase-
281 aling role in mechanical ventilation-induced diaphragmatic weakness and that oxidative stress is an u
282 aling role in mechanical ventilation-induced diaphragmatic weakness and that oxidative stress is requ
283 prolonged mechanical ventilation results in diaphragmatic weakness attributable to fiber atrophy and
284 al muscle fibers is a key pathway leading to diaphragmatic weakness during acute endotoxemia, most li
289 l ventilation is associated with significant diaphragmatic weakness resulting from both myofiber atro
293 sponsible for mechanical ventilation-induced diaphragmatic weakness will provide the knowledge requir
294 unidentified type of infantile myopathy with diaphragmatic weakness, areflexia, respiratory distress
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