ライフサイエンスコーパス: diathesis

1 sely proportional to the level of underlying diathesis.

2 nasal polyposis, endometriosis, and allergic diathesis.

3 ding underwent an investigation for bleeding diathesis.

4 alone may not explain the observed bleeding diathesis.

5 ted TSP2 KO mice did not rescue the bleeding diathesis.

6 ilies suggests a common, or shared, familial diathesis.

7 l skin barrier defect, and a profound atopic diathesis.

8 hiatric illness (the stressor) but also by a diathesis.

9 sses thought to be important in the allergic diathesis.

10 neonatal hemorrhage and a lifelong bleeding diathesis.

11 essive neurologic dysfunction and a bleeding diathesis.

12 onset forms of this condition share the same diathesis.

13 s associated with ultimate cure of the ulcer diathesis.

14 normal in association with a severe bleeding diathesis.

15 e grossly normal adult mice with no bleeding diathesis.

16 ail-bleeding measurement revealed a bleeding diathesis.

17 rs are manifestations of a common underlying diathesis.

18 ssue damage, and remodeling in the asthmatic diathesis.

19 t limited clinical evidence of an infectious diathesis.

20 evels of FVIII that contribute to a bleeding diathesis.

21 severe manifestations of a common underlying diathesis.

22 th muscle (ASM), contribute to the asthmatic diathesis.

23 associated with other diseases of the atopic diathesis.

24 coagulant effect that produces a hemorrhagic diathesis.

25 PF4/polyanion antibodies and a prothrombotic diathesis.

26 acute promyelocytic leukemia (APL) bleeding diathesis.

27 tation in von Willebrand disease, a bleeding diathesis.

28 ng response in bone and skin, and a bleeding diathesis.

29 such as purpura, which indicates a bleeding diathesis.

30 3 that, when disrupted, can cause a bleeding diathesis.

31 roborated histologic evidence of hemorrhagic diathesis.

32 albuminuria and ameliorate the prothrombotic diathesis.

33 rt that PEA-BP-I and adult BP-I are the same diathesis, 7 to 8x greater familiality in child vs adult

34 t increased several features of the allergic diathesis (AHR, eosinophilia, and IgE), which was concom

35 or VIPAR, and is associated with a bleeding diathesis and a marked reduction in platelet alpha-granu

36 irculating LPA levels and induced a bleeding diathesis and attenuation of thrombosis in mice.

37 previously known as idiopathic haemorrhagic diathesis and commonly known as bleeding calf syndrome)

38 ction of depression with the alcohol genetic diathesis and disturbed parent model.

39 IFN-alpha/beta-dependent lethal hemorrhagic diathesis and for clearing LCMV infection through CTLs.

40 outcomes are exacerbated by a prothrombotic diathesis and hypokalaemia.

41 essive condition characterized by a bleeding diathesis and hypopigmentation of the skin, hair, and ey

42 can noninvasively characterize the asthmatic diathesis and its severity.

43 marker for early activation of an autoimmune diathesis and likely plays a critical role in triggering

44 tations in RASGRP2 that account for bleeding diathesis and platelet dysfunction in 2 unrelated famili

45 ypass surgery complicated by severe bleeding diathesis, and 3 patients had major bleeding events.

46 mpaired visual acuity, nystagmus, a bleeding diathesis, and absent platelet dense bodies, confirming

47 rvive to adulthood with only a mild bleeding diathesis, and fibrinogen-deficient mice show perinatal

48 medications, chronic lung disease, bleeding diathesis, and immunodeficiency.

49 terized by oculocutaneous albinism, bleeding diathesis, and other variable symptoms.

50 yte abnormalities, cardiac failure, bleeding diathesis, and phlebitis.

51 tations that could include rash, hemorrhagic diathesis, and shock.

52 nts have oculocutaneous albinism, a bleeding diathesis, and sometimes develop granulomatous colitis o

53 Thus, the bleeding diathesis appears to reflect the absence of platelet fac

54 ition difficulties to create a depressogenic diathesis as at-risk females reach puberty.

55 onality disorder, which has the same genetic diathesis as schizophrenia, manifests abnormalities in w

56 The in vivo bleeding diathesis as well as the defects in platelet responses t

57 The bleeding diathesis associated with congenital deficiency of facto

58 The bleeding diathesis associated with hereditary factor XI (fXI) def

59 activity (400%), correction of the bleeding diathesis at clinically relevant, low vector doses (5 x

60 nd from a male patient (S14) with a bleeding diathesis attributed to a single amino acid substitution

61 gesting persistence of an underlying disease diathesis between episodes.

62 iciency is associated with a severe bleeding diathesis but no developmental abnormalities, lending we

63 XI deficiency is associated with a bleeding diathesis, but factor XII deficiency is not, indicating

64 None of these lines had an overt bleeding diathesis, but in a FeCl(3) carotid artery thrombosis mo

65 and major depression share a common genetic diathesis, but the anxiety disorders themselves are gene

66 (vWD) is the most common hereditary bleeding diathesis, but the estimated prevalence of acquired vWD

67 L-21 plays an important role in the allergic diathesis by enhancing Th2 cytokine production through m

68 Hemophilia is an X-linked bleeding diathesis caused by a deficiency of either factor VIII o

69 Hemophilia B is a severe X-linked bleeding diathesis caused by the absence of functional blood coag

70 type that promotes the pronounced thrombotic diathesis characteristic of the hypereosinophilic syndro

71 use gray platelet syndrome (GPS), a bleeding diathesis characterized by a lack of alpha granules in p

72 could be explained by the genetic alcoholic diathesis combined with an environmental factor that was

73 We speculate that this underlying diathesis could alter the temporal and spatial cascade o

74 thrombospondin-2 (TSP2), display a bleeding diathesis, despite normal blood coagulation and the lack

75 fied in patients diagnosed with the bleeding diathesis disorder, von Willebrand disease (vWD), on the

76 failure (FHF) in humans produces a bleeding diathesis due in large part to a reduction in the biosyn

77 ed by oculocutaneous albinism and a bleeding diathesis due to absent platelet delta granules.

78 ng of oculocutaneous albinism and a bleeding diathesis due to the absence of platelet dense granules,

79 enied having prior trauma, surgery, bleeding diathesis, fever, chills, or vision changes.

80 f childhood abuse that may contribute to the diathesis for adulthood psychopathological conditions.

81 ic trait variables associated with a genetic diathesis for anorexia nervosa.

82 Chronic stress is a strong diathesis for depression in humans and is used to genera

83 critical time for the emergence of a genetic diathesis for disordered eating.

84 the amygdala and hippocampus may be a shared diathesis for later negative outcomes related to ELS.

85 High hypnotizability may be a diathesis for pathological dissociative states, particul

86 tions are related to the underlying familial diathesis for psychotic disorders.

87 renia patients, who likely share the genetic diathesis for schizophrenia but not the potential confou

88 that are differentially associated with the diathesis for schizophrenia.

89 y-adrenal axis stress-response system in the diathesis for suicidal behaviour.

90 he hypothalamic-pituitary-adrenal axis, as a diathesis for suicide.

91 develop a coherent model for the biological diathesis for suicide.

92 due, at least in part, to a greater familial diathesis for the disorder.

93 before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes an

94 The bleeding diathesis has been attributed to delta storage pool defi

95 with pathophysiologic importance for the SLE diathesis in African Americans.

96 ene product and amelioration of the bleeding diathesis in animals with hemophilia B.

97 2 antibodies contribute to the prothrombotic diathesis in antiphospholipid syndrome.

98 ited platelet defect accounts for a bleeding diathesis in approximately 1:20,000 individuals.

99 els (8I U/mL) and correction of the bleeding diathesis in FIX knock-out mice.

100 let FVIII demonstrably improved the bleeding diathesis in FVIIInull mice independent of the platelets

101 and demonstrate amelioration of the bleeding diathesis in haemophilia B mice.

102 C)-2 is associated with only a mild bleeding diathesis in humans and mice.

103 ed the existence of a generalized autoimmune diathesis in patients with multiple sclerosis.

104 sumptive coagulopathy underlies the bleeding diathesis in these older embryos.

105 lar matrix (ECM) abnormality to the bleeding diathesis in thrombospondin-2 (TSP2) knockout (KO) mice.

106 l prefrontal cortex (vmPFC)) and this stress diathesis, in maltreated youth were not previously inves

107 However, other indicators of bipolar diathesis including recent maniclike symptoms and family

108 g from additive or multiplicative effects of diathesis, including culture, and stressful experiences.

109 studies indicate a biological basis for this diathesis, indicating the importance of neurobiological

110 This diathesis is expressed as the tendency to develop more p

111 The characteristic bleeding diathesis is the most notorious manifestation of the dis

112 This diathesis may be reflected in tendencies to experience m

113 Biomarkers related to the diathesis might help to inform risk-assessment procedure

114 ) associated with thrombocytopenia, bleeding diathesis, miosis, and tubular myopathy in patients with

115 tigated the predictive potential of a stress-diathesis model for suicidal behavior based on correlate

116 The authors propose a stress-diathesis model in which the risk for suicidal acts is d

117 The stress-diathesis model may not be an appropriate paradigm for p

118 The stress-diathesis model posits that suicide is the result of an

119 ted for phobias the prediction of the stress-diathesis model that the magnitude of stress at onset is

120 None of the 3 tests of the stress-diathesis model was confirmatory: (1) the risk of phobia

121 This review includes a hypothesized stress-diathesis model, which has implications for detection of

122 hose oculocutaneous albinism (OCA), bleeding diathesis, neutropenia, and history of recurrent infecti

123 various expressions of an underlying common diathesis of abnormal regulation of basic threat-respons

124 s, infection may have a role in the bleeding diathesis of cirrhosis.

125 mplicated recently in some of the infectious diathesis of cystic fibrosis.

126 ic expression of hFVIII rescued the bleeding diathesis of hemophilic mice lacking endogenous FVIII.

127 g human factor IX could correct the bleeding diathesis of mice with hemophilia B.

128 reactivity is associated with an autoimmune diathesis of the mother.

129 nd their absence contributes to the bleeding diathesis of Wiskott-Aldrich syndrome.

130 trate how multiple risk factors and a family diathesis often go undetected, resulting in tragic conse

131 ion in females was predicted by an alcoholic diathesis only when combined with the disturbed adoptive

132 t (environmental) stressors and a trait-like diathesis or susceptibility to suicidal behaviour, indep

133 on the depression risk are dependent on the diathesis or vulnerability, implying multiplicative inte

134 m disease proposes that an alcoholic genetic diathesis predisposes to depression in females but alcoh

135 tigated a small Dutch family with a bleeding diathesis, prolonged prothrombin, and activated partial

136 e promyelocytic leukemia leads to a bleeding diathesis reflective of excessive cell surface annexin 2

137 17F mutation, but its role in the thrombotic diathesis remains obscure.

138 nts, especially those with a severe bleeding diathesis, significantly easier and safer.

139 had altered platelet biology and a bleeding diathesis similar to that seen in patients with Quebec p

140 he interaction with MAOA-LPR better fits the diathesis stress model, with the 3.5R/4R allele conferri

141 n the level of food reinforcement, while the diathesis stress or dual-gain model only influences one

142 lysis of differential susceptibility (versus diathesis stress) are reviewed.

143 The findings support a diathesis-stress hypothesis in which genetically seizure

144 or depression, supporting the multiplicative diathesis-stress model for this disease.

145 on health have relied heavily on the classic diathesis-stress model that treats genetic variations an

146 The authors propose a diathesis-stress model to describe how pathological diss

147 The diathesis-stress theory for depression states that the e

148 This hypothesis is often tested with a "diathesis-stress" model, in which genes confer excess vu

149 t from anticoagulation coupled with bleeding diathesis such as acquired von Willebrand syndrome.

150 veloped normally with no signs of a bleeding diathesis, suggesting that low TF expression can maintai

151 associated with a mild to moderate bleeding diathesis that is most commonly found in persons of Jewi

152 y, the biological substrates underlying this diathesis to medical and psychiatric morbidity have been

153 rize the work that has defined the inherited diathesis toward atrial fibrillation, outline the geneti

154 nding of the molecular basis of the bleeding diathesis type 2N VWD.

155 e genetics of brain function and the genetic diathesis underlying complex psychiatric disorders.

156 A bleeding diathesis was clinically evident from days 5 to 12 after

157 Phenotypic correction of the bleeding diathesis was demonstrated by survival of all treated mi

158 The predictive potential of the diathesis was tested by determining whether clinical cor

159 o identify the genetic cause of the bleeding diathesis, we performed whole exome sequencing analysis

160 Although CD36(-) mice do not have a bleeding diathesis, we show here that they do have significantly

161 e design, there remains an apparent bleeding diathesis, which leads to increased transfusion requirem

162 are manifestations of an affective disorder diathesis with a puerperal trigger.