ライフサイエンスコーパス: diauxic

1 hereas the remaining two models exhibit both diauxic and non-diauxic growth patterns.

2 mycin treatment, and late stages of shift to diauxic conditions and nitrogen depletion suggests that

3 is the only FAA induced during the critical diauxic/early post-diauxic transition.

4 Interestingly, a diauxic effect was observed with sequential consumption

5 In particular, the prediction of diauxic growth corresponds to "extinction" of one of the

6 chia coli and Bacillus subtilis by following diauxic growth curves, assays to estimate the utilizatio

7 two approaches were used in the analysis of diauxic growth in Escherichia coli.

8 Bi-phasic or diauxic growth is often observed when microbes are grown

9 Our results show that classical diauxic growth is only one extreme on a continuum of gro

10 Diauxic growth is usually interpreted as an adaptation t

11 This was reflected by diauxic growth kinetics on medium containing mixed carbo

12 We investigated the diauxic growth of Saccharomyces cerevisiae and demonstra

13 and single gene perturbation phenotypes for diauxic growth on glucose/lactose and glucose/glucose-6-

14 A diauxic growth pattern was obtained when E. coli was gro

15 The Brandt et al. model always predicts the diauxic growth pattern, whereas the remaining two models

16 ning two models exhibit both diauxic and non-diauxic growth patterns.

17 In contrast, under diauxic growth shift conditions, Dhh1 and Pat1 are found

18 of Dhh1 and Pat1 change as cells undergo the diauxic growth shift.

19 Diauxic growth with glucose and lactose was not affected

20 This phenotype exhibits diauxic growth, a manifestation of the winner-take-all d

21 nations of polysaccharides also give rise to diauxic growth, other combinations result in synergistic

22 of substrate consumption patterns including diauxic growth, simultaneous consumption, and bistable g

23 (1) In almost all the cases of diauxic growth, the "preferred" substrate is the one tha

24 ions counting from the beginning of the post-diauxic growth.

25 nes are inhibited and the bacterium exhibits diauxic growth.

26 such systems, especially those resulting in diauxic growth.

27 then undergo a transient growth delay, the "diauxic lag," while inducing genes to metabolize the les

28 arger upfront growth cost but also a shorter diauxic lag.

29 yces cerevisiae display short or nonexistent diauxic lags when grown in mixtures of glucose (preferre

30 present only during the log and diauxic/post-diauxic periods, indicating that N-myristoylproteins pre

31 ed defective aerobic respiration in the post-diauxic phase but retained normal intrinsic mitochondria

32 s post-translationally activated in the post-diauxic phase of growth and that it localizes to mitocho

33 protein levels are increased by H2O2, in the diauxic phase of normal growth conditions, and in cells

34 ogarithmic growth, worsened through the post-diauxic phase, and became extreme in stationary phase.

35 the levels of phytoceramide during the post-diauxic phase, demonstrating that the activation of Isc1

36 C, which resides in mitochondria in the post-diauxic phase, showed defective aerobic respiration in t

37 In the post-diauxic phase, the cooperative effect of the pheromone a

38 ory substrates into mitochondria in the post-diauxic phase.

39 drial respiratory electron transport in post-diauxic-phase cells under conditions of lethal heat shoc

40 is normally present only during the log and diauxic/post-diauxic periods, indicating that N-myristoy

41 athways and the pathways that respond to the diauxic shift (including glycolysis and the citric acid

42 catabolite repression, the aerobic/anaerobic diauxic shift and amino acid biosynthesis pathway repres

43 /3 and SNO2/3 mRNAs are induced prior to the diauxic shift and decrease in abundance during the postd

44 is down-regulated as cells pass through the diauxic shift and enter stationary phase.

45 omatin structure closes when cells enter the diauxic shift and growth dramatically slows.

46 Puf3p levels are reduced during the diauxic shift and growth on a nonfermentable carbon sour

47 Expression of GTT1 is induced after diauxic shift and remains high throughout the stationary

48 ss of SVF1 is associated with defects in the diauxic shift and the oxidative stress response.

49 show that genes normally induced during the diauxic shift are not properly induced in a ctk1Delta st

50 lysis of expression data from a recent yeast diauxic shift experiment.

51 This method has been validated on diauxic shift experiments and reproduces well known effe

52 e genes failed to be up-regulated across the diauxic shift in a manner similar to the Deltaisc1 strai

53 so is observed, at least in part, during the diauxic shift in batch cultures.

54 ested for the ability to efficiently undergo diauxic shift in the presence and absence of Bcl-x(L).

55 ells, mRNA content was less abundant in post-diauxic shift phase and even less in stationary phase C.

56 transcripts of many genes increased in post-diauxic shift phase as well as stationary phase.

57 xpressed at higher levels at and beyond post-diauxic shift phase.

58 ible homodimeric protein that is involved in diauxic shift reprogramming and has glyoxalase activity.

59 ociation of the Arc1p:GluRS complex upon the diauxic shift to respiratory conditions.

60 ing through the cell cycle, sporulation, and diauxic shift were analyzed.

61 cerevisiae following glucose depletion (the diauxic shift) depends on a profound metabolic adaptatio

62 transition of log phase to stationary phase (diauxic shift) for effective CLS extension.

63 During nutrient limitation (diauxic shift) or after treatment with rapamycin (a spec

64 carbohydrate in the media becomes limiting (diauxic shift).

65 d, CR increased acetyl-CoA levels during the diauxic shift, along with expression of both acetyl-CoA

66 etabolic reprogramming that occur during the diauxic shift, and the expression patterns of many previ

67 period of maximal SNF1 activation beyond the diauxic shift, as indicated by Sak1-dependent T210 phosp

68 premature growth arrest of cells during the diauxic shift, as they adapt to the changing environment

69 nteracts with Snf1 and is induced during the diauxic shift, had an inhibitory role on invasive growth

70 direct target genes are also induced by the diauxic shift, in which glucose levels begin to be deple

71 during log phase and reassembled during the diauxic shift, largely accounting for the differences in

72 the Mot1-repressed genes are involved in the diauxic shift, stress response, mating, or sporulation.

73 izes Snf1 activity throughout and beyond the diauxic shift, thus optimizing the coordination of nucle

74 mentable carbon source metabolism during the diauxic shift, thus suggesting a mechanism for the defec

75 onQ) cells are initiated within hours of the diauxic shift, when cells have scavenged all the glucose

76 3 mutants, SNZ1 mRNA is induced prior to the diauxic shift, when SNZ2/3 mRNAs are normally induced.

77 e possibility that mitochondria may initiate diauxic shift-associated regulation of nucleus-encoded g

78 We describe a previously unknown type of diauxic shift-dependent modulation of the intracellular

79 histone deacetylase complex was required for diauxic shift-induced H4 and H2B deposition onto rDNA ge

80 er exhausting glucose, generating a reversed diauxic shift.

81 2, two targets of Pdr1, also overgrow at the diauxic shift.

82 agments after rapamycin treatment and during diauxic shift.

83 expression of numerous yeast genes after the diauxic shift.

84 very similar to those in cells undergoing a diauxic shift.

85 the metabolic remodeling associated with the diauxic shift.

86 ells undergo the metabolic transition at the diauxic shift.

87 (Ser(2)) phosphorylation observed during the diauxic shift.

88 n of glycogen accumulation that precedes the diauxic shift.

89 atch cultures just before they undergo this "diauxic shift." Essentially the same pattern was found b

90 that the yeast DJ-1 homologs have a role in diauxic-shift (DS), characterized by metabolic reprogram

91 hese genes were found to be clustered in the diauxic-shift experiment as well.

92 carbon upshifts and downshifts (for example, diauxic shifts) without adjustable parameters.

93 s a trade-off between lost growth during the diauxic switch and the long-term growth potential of the

94 rowth, but causes a significant delay in the diauxic transition from glucose to acetate.

95 The importance of ADR1 during the diauxic transition is illustrated by the observation tha

96 nscription factors are active only after the diauxic transition, when glucose is depleted and energy-

97 duced during the critical diauxic/early post-diauxic transition.