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1 Me2NH2)[In(ABDC)2] (ABDC, 2-aminobenzene-1,4-dicarboxylate).
2 MOF-74, DOBDC(4-) = 2,5-dihydroxybenzene-1,4-dicarboxylate).
3 1 on both alpha-KG and glutarate (another C5-dicarboxylate).
4 te reuptake blocker, l-trans-pyrrolidine-2,4-dicarboxylate.
5 obtained in one case with dimethyl acetylene dicarboxylate.
6 nitrogen, and 4 carboxylate of pyridine 2,4-dicarboxylate.
7 ate, but not by succinate, a nonexchangeable dicarboxylate.
8 ng buffer containing one fully (13)C-labeled dicarboxylate.
9 dehyde and methyl carbon atoms to form a 1,2-dicarboxylate.
10 hyl spiro[cycloprop[2]ene-1,9'-fluorene]-2,3-dicarboxylate.
11 onies and grew poorly on organic nitrogen or dicarboxylates.
12 ns and substrate specificity for four-carbon dicarboxylates.
13 ated that retained some ability to transport dicarboxylates.
14 2 mediate Na(+)-coupled transport of various dicarboxylates.
15 cells that shows preference for citrate over dicarboxylates.
16 a novel asymmetric alkylation of allylic gem-dicarboxylates.
17 an additional site on the enzyme for binding dicarboxylates.
18 PA5530 gene was induced by extracellular C5-dicarboxylates.
19 ,5S,6R-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate) (0.3, 1.0, and 3.0 mg/kg, s.c.) dose depe
20 agonist APDC [(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate] (0.1 mum) or group III agonist l-(+)-2-am
21 1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate 1 (LY354740) bearing C4-thiotriazole subst
22 cycloaddition of dimethyl cyclobut-1-ene-1,2-dicarboxylate (1) with cyclohexene (7) afforded two phot
23 these compounds are maleate (7), allene-1,3-dicarboxylate (10), cis,cis-muconate (11), trans,trans-m
24 e (4Z,10Z)-dimethyl cyclodeca-4,10-diene-1,4-dicarboxylate (10), which subsequently isomerized to pro
25 pyridine (10), dimethyl 2,2'-bipyridine-4,4'-dicarboxylate (11), 1,10-phenanthroline (12), 2,9-dimeth
28 ,6S-2-amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylate 2 (LY541850), exhibited an unexpected mGlu
29 nyl-4-phenylethynyl-1, 4-dihydropyridine-3,5-dicarboxylate (2) were obtained via an ester derived fro
30 is about 2000, releasing cyclopentanone-2,4-dicarboxylate (22) and two other precursors of this comp
31 oxylated 2E-fluoro-2,4-pentadienoate and the dicarboxylated 2E-fluoro-2-en-4-ynoate being the most po
32 syntheses of dimethyl 2,2'-bithiophene-4,4'-dicarboxylate (3), dimethyl 2,2'-bithiophene-3,4'-dicarb
33 eptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate (3.0 microg/side) mimicked the effect of L
34 of a porous MOF, Zn(4)O(trans-4,4'-stilbene dicarboxylate)(3), with Br(2) results in diastereoselect
35 boxylate (3), dimethyl 2,2'-bithiophene-3,4'-dicarboxylate (4), and dimethyl 2,2'-bithiophene-3,3'-di
37 r reaction of dimethyl 1,2,4,5-tetrazine-3,6-dicarboxylate (7) with the optically active enol ether 6
38 ethylspiro[bicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate-7,1'-cycloprop ane] (B'), A:B', and A':B;
39 diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate (8), and i-Pr2NEt and their coupling in di
40 linkers (oxalate, 6; fumarate, 8; acetylene dicarboxylate, 9; cis,cis-muconate, 11; trans,trans-muco
41 ors (X-(CH(2))(n)-X) such as alkyl dithiols, dicarboxylate acids, and alkanethiol shells capped on na
45 ed conditions, the alkylation of various gem-dicarboxylates afforded monoalkylated products in high y
46 binding to site IIf The decrease in matrix [dicarboxylate] allows O2 access to reduced site IIf, the
47 njugate was reduced by the OAT1-exchangeable dicarboxylates alpha-ketoglutarate, glutarate, and adipa
50 enzymes indicating that the ability of this dicarboxylate analogue to bridge the arginines precisely
51 old, and concomitantly decrease the K(i) for dicarboxylate analogues of l-aspartate by up to 40-fold.
52 in conjunction with di-tert-butyl hydrazine dicarboxylate and an inorganic base provides a variety o
53 ew MOF [Yb2(BDC)3(DMF)2]H2O (BDC=benzene-1,4-dicarboxylate and DMF=N,N-dimethylformamide) under solvo
54 likely orients amino acid residues near the dicarboxylate and FAD binding site, which facilitates fo
55 col utilizes a combination of an iodobenzene dicarboxylate and iodine to functionalize a series of ac
56 de at 0.6 V, whereas diethyl 2,5-dioxahexane dicarboxylate and lithium propionate form on the Sn elec
57 + 2] cycloaddition between vinylcyclopropane dicarboxylates and 3-nitroindoles has been developed.
58 inity, disulfonic stilbene-sensitive flux of dicarboxylates and citrate across the plasma membrane by
60 DH4) contain all key residues for binding of dicarboxylates and quinones, but the enzyme showed the l
62 The transporter does interact with other dicarboxylates and tricarboxylates but with considerably
63 7 ([Zr6O4(OH)4 (bpdc)6], bpdc: 4,4'-biphenyl dicarboxylate) and UiO-abdc ([Zr6O4(OH)4 (abdc)6], abdc:
64 y structures of MOFs UWDM-2 (1,4-diazophenyl-dicarboxylate) and UWDM-3 (1,4-biphenyl-dicarboxylate) s
65 not group II [(2R,4R)-4-aminopyrrolidine-2,3-dicarboxylate] and III [L-AP 4 (L-(+)-2-amino-4-phosphon
67 ne (PC), and sphingomyelin (SM) cations with dicarboxylate anions are shown to charge-invert the posi
68 studied as receptors for the recognition of dicarboxylate anions of varying chain length in aqueous
69 ape complementarity between the host and the dicarboxylate anions, which is nicely reflected in the s
72 mGluR agonists (2R,4R-4-aminopyrrolidine-2,4-dicarboxylate (APDC) and L(+)-2-amino-4-phosphonobutyric
73 3)) agonists (2R, 4R)-4-aminopyrrolidine-2,4-dicarboxylate (APDC) or (2S,2'R,3'R)-2-(2'3'-dicarboxycy
74 mGluR agonist, 2R,4R 4-aminopyrrolidine-2,4-dicarboxylate (APDC), did not alter thermal sensitivity
77 indicating that transport and utilization of dicarboxylates are important for virulence of DC3000.
79 owly in culture than wild-type bacteria when dicarboxylates are the only available carbon source.
81 ) and dimethyl 3,5-dimethyl-1-pyrazoline-3,5-dicarboxylate as a specific organocatalyst has been foun
82 e yield by employing neat dimethyl acetylene dicarboxylate as the dienophile, followed by catalytic h
83 new hosts against a series of alkyl and aryl dicarboxylates as well as a range of phosphoanionic spec
84 other transcriptional regulators involved in dicarboxylate assimilation, suggesting that MifR might i
87 complex of a 1,10-phenanthroline containing dicarboxylate axle with a 1,10-phenanthroline containing
88 benzo[24]crown-8 wheels, (3) 2,6-naphthalene dicarboxylate axles with tetra-imidazolium macrocycle wh
89 ary for transport was a four-carbon terminal dicarboxylate backbone and that productive substrate-tra
90 phiphilic ligand, 4'-tert-butyl-biphenyl-3,5-dicarboxylate (BBPDC), with Zn(NO(3))(2), Co(NO(3))(2),
91 O) as axial ligands and 2,2'-bipyridine-6,6'-dicarboxylate (bda) as the equatorial ligand, we have sy
92 of nonpolar functional groups on the benzene dicarboxylate (BDC) linker in the pillared DMOF-1 [Zn2(B
93 to the conservation of amino acids near the dicarboxylate binding sites of the two enzymes is that t
96 ults in succinate-dependent reduction of the dicarboxylate-binding site of complex II (site IIf); (b)
97 nedicarboxylate (NDC), and BTE/biphenyl-4,4'-dicarboxylate (BPDC), to give four metal-organic framewo
98 mu-O)(3)Mn(IV)(tmtacn)](2+) into the active, dicarboxylate-bridged [(tmtacn)Mn(III)(mu-O)(mu-RCOO)(2)
100 eptor unit 1 with several linear and angular dicarboxylate bridging ligands afforded hitherto unknown
101 highly stable MOFs (1 and 2) using elongated dicarboxylate bridging ligands derived from Cp*Ir(L)Cl c
103 is apparent for several of the alkylaminium dicarboxylates but not for the alkylaminium monocarboxyl
104 tion of the transport and metabolism of C(4)-dicarboxylates, but they are not highly related by seque
105 ethyl]-amino]propyl]-1,3-benzodiox azole-2,2-dicarboxylate], but not after administration of beta1, b
108 ([Zr6O4(OH)4 (abdc)6], abdc: 4,4'-azobenzene dicarboxylate) by single-crystal nanoindentation, high-p
109 ous DEAD reagent bis(perfluorohexylethyl)azo dicarboxylate (C(6)F(13)(CH(2))(2)O(2)CN=NCO(2)(CH(2))(2
110 byproducts from bis(perfluorohexylpropyl)azo dicarboxylate (C(6)F(13)(CH(2))(3)O(2)CN=NCO(2)(CH(2))(3
111 reagent perfluorooctylpropyl tert-butyl azo dicarboxylate (C(8)F(17)(CH(2))(3)O(2)CN=NCO2(t)Bu, F-DE
112 rapid efflux of succinate/fumarate and other dicarboxylates capable of competitively binding to site
114 such as overexpression of the mitochondrial dicarboxylate carrier result in increased ROS formation
118 ecedented selectivity for fum(2-) over other dicarboxylate competitors, including its cis isomer male
121 ues, Arg-349 and Asp-373, of the renal Na(+)/dicarboxylate cotransporter (NaDC-1) have been shown in
128 ithin the substrate access pore of the Na(+)/dicarboxylate cotransporter, either in a transmembrane h
129 s most closely related to a mammalian sodium dicarboxylate cotransporter-a membrane protein that tran
130 uctural similarity to the members of the Na+-dicarboxylate cotransporter/Na+ -sulfate cotransporter (
132 aureus is a homologue of the mammalian Na(+)/dicarboxylate cotransporters (NaDC1) from the solute car
140 hoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (DDB) analogues were designed and synthesi
141 gene encodes 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase (HMPDdc), an enzyme involved
142 nsporter function by L-trans-pyrrolidine 2,4-dicarboxylate decreased the rate of glutamate uptake but
143 8 [(-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate] decreased nicotine, but not food, self-ad
144 carboxylates and 1.1 to 2.2 for alkylaminium dicarboxylates, dependent on the molecular functionality
145 cluding citrate and other tricarboxylate and dicarboxylate derivatives, this ratio ranged from 0.0003
146 -anisylformamidinate), linked by unsaturated dicarboxylate dianions of various lengths have been prep
151 rate levels, we hypothesize that by allowing dicarboxylate efflux from the matrix, PTP opening during
154 ydrogenation of dibenzyl 5-dipyrroketone-2,9-dicarboxylates followed by decarboxylative iodination af
155 ann reaction of 2-naphthols with acetone-1,3-dicarboxylates, followed by an intramolecular Friedel-Cr
156 legans may lead to decreased availability of dicarboxylates for cellular production of metabolic ener
157 feature a new preparation of cis-cyclobutane dicarboxylates from commercially available coumalate sta
158 Thus, SdcS facilitates the transport of the dicarboxylates fumarate, malate, and succinate across th
159 BDC) (H2DHBDC(2-) = 2,5-dihydroxybenzene-1,4-dicarboxylate) function as selective sensors for ammonia
160 selectivity follows: phenolates >/= aromatic dicarboxylates > aromatic monocarboxylates > benzenesulf
161 where TTh-CO2 = 2,2':5',2''-terthienyl-5,5''-dicarboxylate, has also been prepared and employed in th
163 des olefins along with unsaturated mono- and dicarboxylates in distributions with adjustable widths.
164 rea receptors form exothermic complexes with dicarboxylates in DMSO, with a near zero entropic contri
165 ntributes to favorable binding constants for dicarboxylates in water, as well as a high degree of sel
166 ,5S,6R-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate) in adult, but not prepubertal, mice born
167 da(2-) being [2,2':6',2''-terpyridine]-6,6''-dicarboxylate, including complex [Ru(IV)(OH)(tda-kappa-N
168 agonist APDC [(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate] induced a concentration-dependent decreas
169 In Staphylococcus aureus, the transport of dicarboxylates is mediated in part by the Na+-linked car
171 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate) is characterized for the removal of CO2 f
172 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate), is shown to undergo a topotactic oxidati
173 I)(bda)(isoq)2] (bda is 2,2'-bipyridine-6,6'-dicarboxylate; isoq is isoquinoline) exists as the open-
176 molecular clip 6 and three different linear dicarboxylates led to the formation of neutral molecular
178 d 2) built from [Ir(ppy)(2)(bpy)](+)-derived dicarboxylate ligands (L(1) and L(2)) and Zr(6)(mu(3)-O)
179 than those of the analogous polyunsaturated dicarboxylate linked compounds and reveal at least two s
181 nic framework (MOF) based on a BINAP-derived dicarboxylate linker, BINAP-MOF, was synthesized and pos
182 nstructed from only bipyridyl-functionalized dicarboxylate linker, both mBPV- and mPT-MOF were built
184 chemically unsaturated and fully conjugated dicarboxylate linkers (oxalate, 6; fumarate, 8; acetylen
187 tu ligand exchange with progressively longer dicarboxylate linkers is performed on single crystalline
189 I), were prepared using purely BINAP-derived dicarboxylate linkers or by mixing BINAP-derived linkers
194 1S,2S,5R,6S-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate (LY354740), a potent and pharmacologically
195 ds (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268, (-)-9) and (-)-2-thia-4-aminobi
197 (-)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate (LY389795, (-)-3) is a highly potent and s
199 te citramalyl-CoA, an intermediate in the C5-dicarboxylate metabolic pathway that includes itaconate,
201 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate; mmen = N,N'-dimethylethylenediamine) was
202 ive Ru-bda type (bda is 2,2'-bipyridine-6,6'-dicarboxylate) molecular OER catalysts are proposed to o
203 he hydrogen bond in hydrogen cyclohexene-1,2-dicarboxylate monoanion was determined in chloroform usi
204 (1S,2S,5R,6S-2-aminobicycl[3.1.0]hexane-2,6-dicarboxylate monohydrate) and the group III agonist L-A
205 thynyl-6-phenyl-1,4(+/-)dihydropyridine-3 ,5-dicarboxylate (MRS1191), by the phospholipase C inhibito
208 dihydrokainate, and L-trans-pyrrolidine-2,4-dicarboxylate) nor by replacement of extracellular sodiu
209 nation of dimethyl bicyclo[1.1.1]pentane-1,3-dicarboxylate, obtained from [1.1.1]propellane prepared
211 (4-vinylpyridine)2 (bda=2,2'-bipyridine-6,6'-dicarboxylate) on planar electrodes results in films con
213 ixtures (> or = 81% product) of the reactive dicarboxylate or monocarboxylate intermediates, 2 or 2-h
214 ly, the GT inhibitor l-trans-pyrrolidine-2-4-dicarboxylate (PDC) potentiated, whereas the positive GT
215 ment of transport by L-trans-pyrrolidine-2,4-dicarboxylate (PDC) produced a prolongation of the decay
216 es the reversible hydrolysis of 2-pyrone-4,6-dicarboxylate (PDC) to 4-oxalomesaconate and 4-carboxy-2
217 with 100-500 microM L-trans-pyrrolidine-2,4-dicarboxylate (PDC), an inhibitor of glutamate re-uptake
218 glutamate transport: l-trans-pyrrolidine-2,4-dicarboxylate (PDC), which is a relatively non-selective
220 trate (methyl propiolate, dimethyl acetylene dicarboxylate, phenyl acetylene, ethyl 2,3-butadienoate)
221 t energy absorptions are Mo(2)(4+) delta --> dicarboxylate pi metal-to-ligand charge transfer transit
223 neogenesis using deaminated amino acids with dicarboxylate products of peroxisomal lipid beta-oxidati
224 xanthenone fluorescent scaffold coupled to a dicarboxylate pseudocrown ether receptor to achieve sele
226 nd radicals generated from phenyliodine(III) dicarboxylate reagents and exhibits excellent functional
227 tamate analogue PDC (L-trans-pyrrolidine-2,4-dicarboxylate), reduced the current by approximately 88%
233 cur with high stereospecificity, allylic gem-dicarboxylates serve as synthons for a double allylic tr
234 enyl-dicarboxylate) and UWDM-3 (1,4-biphenyl-dicarboxylate) show that both frameworks are large enoug
238 ane axle component facilitates the complexed dicarboxylate species to be sensed via a fluorescence re
240 including the SdhE assembly factor and bound dicarboxylates, stimulate covalent flavinylation by preo
242 shows that aspartate aminotransferase binds dicarboxylate substrate analogues by bonds to Arg292 and
243 portance of Arg-11 in properly orienting the dicarboxylate substrate by interacting with the charged
244 the R11A-catalyzed protonation at C-5 of the dicarboxylate substrate decreased, while the stereoselec
249 I) lyotropic gyroid phase formed by a gemini dicarboxylate surfactant self-assembly using a combinati
252 pdc) (dobpdc(4-) = 4,4'-dioxidobiphenyl-3,3'-dicarboxylate) that feature step-shaped CO2 adsorption i
253 udied using a structurally similar series of dicarboxylated thiacyanine dyes that bind to the oxide s
254 on strategy, the [3]rotaxane host recognises dicarboxylates through the formation of 1:1 stoichiometr
255 boxylation of 3-hydroxy-2-methylpyridine-4,5-dicarboxylate to 3-hydroxy-2-methylpyridine-5-carboxylat
256 contribution of the polyolefinic alpha,omega-dicarboxylate to the molecular orbital undergoing oxidat
257 4'-(4-benzoate)-(2,2',2''-terpyridine)-5,5''-dicarboxylate (TPY) before being coordinated with iron c
260 mbrane transporters, proteins involved in C4-dicarboxylate transport and utilization, enzymes for bio
261 , consistent with the sites of high-affinity dicarboxylate transport identified based on vesicle stud
263 The absence of the Arabidopsis tonoplast Dicarboxylate Transporter (tDT) in the tdt knockout muta
264 family include a Na(+)- and Li(+)-dependent dicarboxylate transporter from Xenopus intestine and a p
266 ion that increased expression of the dctA C4-dicarboxylate transporter greatly enhanced the Cit(+) ph
267 cell motility 2), SLC13A3 (sodium-dependent dicarboxylate transporter member 3), and PREX1 (phosphat
268 function of the high affinity Na(+)-coupled dicarboxylate transporter NaDC2 in C. elegans may lead t
270 ctural modeling using the x-ray structure of dicarboxylate transporter VcINDY as template and confirm
271 a crystal structure of Vibrio cholerae Na(+)-dicarboxylate transporter VcINDY, from which we generate
273 d functionally characterized a Na(+)-coupled dicarboxylate transporter, SdcS, from Staphylococcus aur
275 ion of the dctA gene, which encodes the C(4)-dicarboxylate transporter, was reduced in a gyrA751 muta
279 hila melanogaster and with the Na(+)-coupled dicarboxylate transporters NaDC1 and NaDC3 identified in
280 the differential substrate specificity among dicarboxylate transporters that underpin their diverse b
281 functionally characterized two Na(+)-coupled dicarboxylate transporters, namely ceNaDC1 and ceNaDC2,
283 on/Na(+) symporter (DASS) family translocate dicarboxylate, tricarboxylate or sulphate across cell me
284 ceptor cyclopropanes (2-arylcyclopropane-1,1-dicarboxylates) under double-catalysis conditions by tre
286 as prepared from diethyl 2-nitropyrrole-3,4,-dicarboxylate via an alkylation, ammonolysis, reduction
287 on of trans-2-aroyl-3-styrylcyclopropane-1,1-dicarboxylates was investigated with different Lewis aci
290 hydroxamates derived from trans-cyclopropyl dicarboxylate were examined as potential TNF-alpha conve
294 f 4-oxo-2,4-dihydrocyclopenta[c]chromene-1,2-dicarboxylates were obtained in moderate to good yields
296 Asymmetric alkylations of allylic geminal dicarboxylates with dialkyl malonates have been investig
297 nding is observed for dicarboxylic acids and dicarboxylates with four-carbon chains, and the binding
299 ceptors form more endothermic complexes with dicarboxylates, with a favorable entropy of association.
300 electron spectra of nine isomeric pyridinium dicarboxylate zwitterions and three nonzwitterionic meth
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