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3 ptor agonist (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S, 3R-ACPD), the group I mGlu recept
4 onist, (1S,3R)-1-aminocyclopentane-trans-1,3-dicarboxylic acid (1S, 3R-t-ACPD), similarly resulted in
5 ) exposure to 1S, 3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) (100 microM) is suppressi
6 of 50 microM (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) depolarized all neurones
7 e effects of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) on synaptic transmission
8 tive mGluR agonist 1-aminocyclopentane-1S,3R-dicarboxylic acid (1S,3R-ACPD) results in contralateral
9 uisqualate and 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) were characterized in the
11 e occluded by 1S,3R-1-aminocyclopentane-1, 3-dicarboxylic acid (1S,3R-ACPD), suggesting they are not
13 ,9b-tetrahydro-3H-cyclopenta[c]quinoline-4,8-dicarboxylic acid (5661118) and the naphthofurandione 3-
15 ectrum mGluR agonist 1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) decreased the frequency of GABA
16 agonist, (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid (ACPD) produced a robust, long-lasting
18 luR agonist (1S,3R)-1-amino-1,3-cyclopentane-dicarboxylic acid (ACPD) were closely correlated with th
19 ol, histamine, trans-1-aminocyclopentyl-1, 3-dicarboxylic acid (ACPD, a glutamatergic metabotropic re
20 ct on either (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD, an mGLU receptor agonist) or 5-
21 activated by (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD; 300 microM) and (R,S)-3,5-dihyd
22 The group I antagonist (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA) and the group II antagonists LY
23 oxyphenylglycine (MCPG) and 1-aminoindan-1,5-dicarboxylic acid (AIDA) but not by the presynaptic meta
24 receptor agonist and (RS)-1-aminoindan-1, 5-dicarboxylic acid (AIDA), a selective mGluR1alpha antago
25 this challenge with 1,4-bicyclo[2.2.2]octane dicarboxylic acid (BODCA)-MOF, a metal-organic framework
27 he uptake of the 1:1 chelate of pyridine-2,6-dicarboxylic acid (DPA(2,6)) and Ca(2+) into developing
28 tion to convert 2-furoic acid into furan-2,5-dicarboxylic acid (FDCA)--a highly desirable bio-based f
29 of AlCl(3).6H(2)O with 2,2'-bipyridine-5,5'-dicarboxylic acid (H(2)bpydc) affords Al(OH)(bpydc) (1,
30 he phenol groups in 2,5-dihydroxybenzene-1,4-dicarboxylic acid (H4DOBDC) have been replaced by thioph
31 on of MnCl2 with 2,5-disulfhydrylbenzene-1,4-dicarboxylic acid (H4DSBDC), in which the phenol groups
32 of WT astrocytes to l-trans-pyrrolidine-2,4-dicarboxylic acid (l-trans-PDC) or by partial suppressio
33 agonist, (-)-2-oxa-4-aminobicylco hexane-4,6-dicarboxylic acid (LY379268), antagonizes reinstatement
34 st (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylic acid (LY379268; 0.3-1 mg/kg i.p.) increased
35 ,3S)-(1-biphenylyl-4-carbonyl)piperazine-2,3-dicarboxylic acid (PBPD, 16b) displays an unusual select
36 amate receptor antagonist cis-2,3-piperidine dicarboxylic acid (PDA) increased paired-pulse depressio
37 lock the On-pathway; and cis-2, 3 piperidine dicarboxylic acid (PDA) to block the Off-pathway and the
38 a combination of APB and cis-2,3 piperidine dicarboxylic acid (PDA) was used to isolate the contribu
40 atergic transmission with cis-2,3 piperidine dicarboxylic acid (PDA, 3.3-3.8 mM, n = 3) or laser-indu
42 ate reuptake blocker l-trans-pyrrolidine-2,4-dicarboxylic acid (PDC) (10 nmol per side), the D(1)-lik
43 mate uptake inhibitor, trans-pyrrolidine-2,4-dicarboxylic acid (PDC) for 3 weeks, or a higher level (
44 te reuptake blocker, l-trans-pyrrolidine-2,4-dicarboxylic acid (PDC), were made in the freely moving
46 nd 1-(phenanthrene-2-carbonyl)piperazine-2,3-dicarboxylic acid (PPDA), have discrete binding modes an
47 enzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008) as a micromolar inhibitor of
49 GluRs by the agonist 1-aminocyclopentane-1,3-dicarboxylic acid (tACPD) inhibited NMDA but not amino-3
50 luR agonist ISR,3RS-1-aminocyclo-pentane-1,3-dicarboxylic acid (tACPD) limited the anatomical and beh
52 In addition, 1-aminocyclopentane-trans-1,3-dicarboxylic acid (trans-ACPD), a group I mGluR agonist,
53 MDA) and (+/-)-1-aminocyclopentane-trans-1,3-dicarboxylic acid (trans-ACPD)-stimulated calcium flux w
55 otection of the hydroxy groups to give novel dicarboxylic acid 11 or dialdehyde 16 in practical yield
56 iazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2, 6-dicarboxylic acid 14a (LY2812223) was further characteri
60 roexcitants 3-(carboxymethyl)pyrrolidine-2,4-dicarboxylic acid 43, alpha-kainic acid 12, alpha-isokai
61 mGluR agonist, 1-aminocyclopentane-trans-1,3-dicarboxylic acid [(1S, 3R)-ACPD, 0.5 nmol/side] and amp
62 luR agonist (1S,3R)-1-amino-1,3-cyclopentane-dicarboxylic acid [(1S,3R)-ACPD], group I/II antagonist
63 honopionic acid (L-AP3), (RS)-aminoindan-1,5-dicarboxylic acid and (RS)-alpha-methylserine-o-phosphat
64 modate the bulky aromatic ring of a pyridine dicarboxylic acid and a negative charge at the C3 but no
65 sporter inhibitors, L-trans-pyrrolidine-2, 4-dicarboxylic acid and dihydrokainic acid, were plotted a
67 h a severalfold reduction in very long chain dicarboxylic acid and omega-hydroxy fatty acids typical
69 n of the aldimine of 4-aminocyclopentane-1,3-dicarboxylic acid and PMP (20), which disrupts an electr
74 mides) derived from 3,5-diamino-pyrazine-2,5-dicarboxylic acid bearing neutral and anionic groups wer
75 ining [6,6']bi[thieno[3,4-b]thiophenyl]-2,2'-dicarboxylic acid bis-(2-butyloctyl) ester (BTT) and 4,8
76 eatment of RPA with oxidizing agent, diazene dicarboxylic acid bis[N,N-dimethylamide] (diamide), sign
77 agonist (1(S), 3(R)]-1-aminocyclopentane-1,3-dicarboxylic acid but not by the group I-specific agonis
78 tropic agonist trans-1-aminocyclopentane-1,3-dicarboxylic acid but were not significantly displaced b
79 birch pulp derivate, nanofibrillated anionic dicarboxylic acid cellulose (DCC), having widths of fibr
80 vary considerably in the presence of various dicarboxylic acid chelators, suggesting that the similar
81 zo)-24-crown-8 by reaction with pyridine-2,6-dicarboxylic acid chloride in 42 and 48% yields, respect
82 title compounds was carried out by reacting dicarboxylic acid chlorides with oximes in the presence
84 O(-)](2), is a colorless insulator where the dicarboxylic acid cocrystallizes with two of its monoani
85 etween a suite of various monocarboxylic and dicarboxylic acid concentrations are consistent with doc
90 In 2002, the plasticizer 1,2-cyclohexane dicarboxylic acid diisononyl ester (DINCH) was introduce
91 ubstituted derivatives of cis-piperazine-2,3-dicarboxylic acid display improved relative affinity for
93 e reuptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylic acid enhanced the effects of intra-amygdala
95 ety in 7-oxabicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylic acid esters serves as both a tunable electr
96 almitate by cultured fibroblasts and urinary dicarboxylic acid excretion; and (5) hepatic lipid perox
97 e dicarboxylic acid linker with 2,3-pyrazine-dicarboxylic acid furnished a highly selective nanomolar
98 uded ellagitannins (1-11), gallic acid (12), dicarboxylic acid glucosides (13-15), hydrojuglone gluco
100 ached to the N(1) position of piperazine-2,3-dicarboxylic acid have been synthesized to probe the str
102 lmethyl]-4-hydroxy-bicy clo[3.1.0]hexane-2,6-dicarboxylic acid hydrochloride (LY3020371.HCl, 19f), a
106 ogenous amino acids, L-trans-pyrrolidine-2,4-dicarboxylic acid in the presence of 8.3 mM glucose pote
107 romethyl carboxylic acid indolylfulgimide 4, dicarboxylic acid indolylfulgimide 5, and carboxylic aci
108 involves the transformation of imidazole-4,5-dicarboxylic acid into dissymmetrically disubstituted I4
112 Replacement of the Pro(6) residue and the dicarboxylic acid linker with 2,3-pyrazine-dicarboxylic
116 ermined urinary concentrations of a tetranor-dicarboxylic acid metabolite of F2-isoprostanes (F2IP-M)
118 nal 4-chlorophenylhydrazones showed that the dicarboxylic acid moiety of CPHM is essential for activi
119 ween inhibitor potency and the length of the dicarboxylic acid molecules suggests a distance of appro
120 mGluR receptor antagonists 1-aminoindan-1,5-dicarboxylic acid or L-(+)-2-amino-3-phosphonopropionic
122 , synthesis of the seven carbon alpha, omega-dicarboxylic acid pimelate moiety and assembly of the fu
123 otide receptor family containing CysLTRs and dicarboxylic acid receptors with trans-activator reporte
124 quisqualate, and 1-aminocyclopentane-1S, 3R-dicarboxylic acid resulted in a marked accumulation of [
125 S,2R,5R,6R)-2-amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid scaffold to generate mGlu2/3 antagonis
126 residue and might provide recognition via a dicarboxylic acid structure, we screened cDNAs within th
127 high density on a putatively nonfermentative dicarboxylic acid substrate depends on a malolactate exc
128 red necessary for energy production from the dicarboxylic acid substrates malate, succinate, and fuma
129 rary, based on a symmetrical isoindoline-5,6-dicarboxylic acid template and including the optimized b
130 g (SH) chemicals such as diglycidyl ether or dicarboxylic acid terminated polydimethylsiloxane (PDMS-
132 The AAA+ domain of Sinorhizobium meliloti C4-dicarboxylic acid transport protein D (DctD) is sufficie
133 the expression of genes encoding a predicted dicarboxylic acid transport system, a putative formate t
134 rt that a SLC26/SulP protein acts as a C(4) -dicarboxylic acid transporter and an unexpected new func
136 ic polyesters varying in the length of their dicarboxylic acid unit and of poly(butylene adipate-co-t
140 id (PMPA) and 4,4'-phosphinicobis(butane-1,3-dicarboxylic acid) (PBDA) were built by a computational
142 Cl2 and H4DSBDC (2,5-disulfhydrylbenzene-1,4-dicarboxylic acid) leads to the formation of Fe2(DSBDC),
143 cular Ru-bda (H(2)bda = 2,2'-bipyridine-6,6'-dicarboxylic acid) water oxidation catalysts, we carried
144 Trans-ACPD (1-aminocyclopentane-trans-1S,3R-dicarboxylic acid), a broad-spectrum metabotropic glutam
145 ,4''-dihydroxy-[1,1':4',1''-terphenyl]-3,3''-dicarboxylic acid), and three modified terphenyl derivat
146 I) bis(2,2'-bipyridine) (2,2'-bipyridyl-5,5'-dicarboxylic acid), RuDCBPY, into a UiO-67 metal-organic
147 dobpdc = 4,4'-dihydroxy-[1,1'-biphenyl]-3,3'-dicarboxylic acid), the terphenyl derivative Fe2(dotpdc)
148 uR(1) antagonist, AIDA((RS)-1-Aminoindan-1,5-dicarboxylic acid), were examined on nociceptive neurons
149 s (or to a hexameric complex in a "U-shaped" dicarboxylic acid), which is fully expected since the tw
151 Y379268 ((-)-2-oxa-4-aminobicylco hexane-4,6-dicarboxylic acid)] on contextual cue-induced reinstatem
152 te-uptake inhibitor (M-trans-pyrrolidine-2,4-dicarboxylic acid, 1 mum), blocked by a Group II mGluR a
154 nd it was blocked by L-trans-pyrrolidine-2,4-dicarboxylic acid, a blocker of neuronal and glial gluta
155 also incapable of accommodating pyridine-2,6-dicarboxylic acid, a competitive inhibitor of the native
157 ted by acyl transfer from the CoA ester of a dicarboxylic acid, followed by decarboxylation in situ b
158 obile metabolite azelaic acid, a nine-carbon dicarboxylic acid, in the vascular sap of Arabidopsis th
160 c mGluR agonist 1S, 3R-aminocyclopentane-1,3-dicarboxylic acid, it fails to block PI turnover and cha
161 Pyrrole-2,3, 5-tricarboxylic and pyrrole-2,3-dicarboxylic acid, specific degradation products of cate
162 transport inhibitor l-trans-pyrrolidine-2,4-dicarboxylic acid, the neuroprotective effects of halope
163 etrapropoxy-5,17-dibromo-calix[4]arene-11,23-dicarboxylic acid, two 1:1 dimetal:calixarene compounds
164 MOF) derivative in which 2,2'-bipyridyl-5,5'-dicarboxylic acid, UiO-67-DCBPY, is used in place of 4,4
165 ruxillic acid or 2,4-diphenylcyclobutane-1,3-dicarboxylic acid, was readily synthesized from commerci
166 te > > [1(S), 3(R)]-1-aminocyclopentane-1, 3-dicarboxylic acid, with EC50 values of 0.63, 0.67, 2.5,
168 of multimeric RGD compounds constructed on a dicarboxylic acid-containing near-infrared (NIR) fluores
169 o antagonize (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced inhibition of forskolin stimul
170 o antagonize (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid-induced inhibition of forskolin-stimul
178 crystal structure of the KDM4B.pyridine 2,4-dicarboxylic acid.H3K9me3 ternary complex, revealing the
179 pyrolysis of dipicolinic acid (pyridine-2,6-dicarboxylic acid; DPA), a substance found in spores but
180 GluR1 antagonist AIDA [(RS)-1-aminoindan-1,5-dicarboxylic acid] but not by group II mGluR antagonist
184 everal additional markers of ESRD, including dicarboxylic acids (adipate, malonate, methylmalonate, a
185 P450 CYP4A omega-oxidation enzymes to toxic dicarboxylic acids (DCAs) that serve as substrates for p
186 nesoic acid, and finally to farnesol-derived dicarboxylic acids (FDDCAs) which would then be excreted
188 etabolites identified as the chain-shortened dicarboxylic acids 18-COOH-18:4, 18-COOH-18:3, and 16-CO
189 mplementary: maximum binding is observed for dicarboxylic acids and dicarboxylates with four-carbon c
190 ate that YchM can also transport other C(4) -dicarboxylic acids and that its substrate specificity di
191 mpact of water infusion was the greatest for dicarboxylic acids and the least for (hetero-) aromatic
193 saturated and unsaturated fatty acids and of dicarboxylic acids are either unavailable or have been e
196 es nitrogen in symbiosis with soybean, where dicarboxylic acids are its principal carbon substrate.
198 n this work, we sought definitive proof that dicarboxylic acids are produced in diesel engines and th
200 difference in the Ki values for a series of dicarboxylic acids as inhibitors of 5-CHO-H4PteGlu5, sug
201 ilable, Sinorhizobium meliloti utilizes C(4)-dicarboxylic acids as preferred carbon sources for growt
202 ctions of ZrCl(4) and single or mixed linear dicarboxylic acids bearing methyl or azide groups lead t
203 -Arg-Nva-Arg-Tyr-NH(2) using various diamino-dicarboxylic acids containing either di-, tri-, or tetra
204 terminus with monocarboxylic or alpha,omega-dicarboxylic acids containing six to sixteen carbon atom
205 Here we report a novel pathway to odd-carbon dicarboxylic acids directly from glucose in Escherichia
207 ed citronellol, acetaldehyde, ethyl acetate, dicarboxylic acids esters, benzenoids, furans and acetal
209 ectroscopy technique to measure 11 mono- and dicarboxylic acids from plain and KOH impregnated quartz
212 ar condensation of a series of monoesters of dicarboxylic acids have been shown to be highly dependen
213 nalogues than does the alpha-Kg site or that dicarboxylic acids have more than one binding mode on th
216 behavior of a well-defined model system of 9 dicarboxylic acids is investigated directly with complem
217 ith betabeta'-methyl-substituted alpha-omega-dicarboxylic acids of C14-C18 in wild-type animals also
218 e cocrystals contain aliphatic even-numbered dicarboxylic acids of increasing chain length, and as a
219 re covalently cross-linked by acylation with dicarboxylic acids of increasing length, namely the fuma
221 of CCN activation for particles composed of dicarboxylic acids or secondary organic aerosol and ammo
223 1-14C]farnesol and comparing the mass of the dicarboxylic acids produced with the ultraviolet absorpt
225 against both the shorter and the longer keto dicarboxylic acids that could potentially serve as alter
226 ochrome P450 CYP4A omega-oxidation system to dicarboxylic acids that serve as substrates for peroxiso
227 mmonium sulfate enhances the partitioning of dicarboxylic acids to aqueous particles more than curren
228 using high molecular weight symmetrical PEG dicarboxylic acids to link the side chains of lysine res
229 stenol, several secondary fatty alcohols and dicarboxylic acids were identified for the first time in
231 diamino-1,2,3,5,6,7-hexahydro-s-indacene-2,6-dicarboxylic acids were synthesized and the structures a
232 zed reaction of readily available tripyrrane dicarboxylic acids with 1,3-azulenedicarbaldehyde, follo
233 n with hex-3-enedioic acid gives unsaturated dicarboxylic acids with adjustable mean chain lengths as
235 ) (a standard criterion for non-H-bonding in dicarboxylic acids) for both 1 and 2 in water and also f
238 mpounds such as phenols and acids, aliphatic dicarboxylic acids, and reduced nitrogen species such as
239 ored carbon substrates, including starch and dicarboxylic acids, as well as sucrose, major amino acid
240 0 parts per million) that includes mono- and dicarboxylic acids, dicarboximides, pyridine carboxylic
241 selective for VFAs, it shows no response to dicarboxylic acids, hydroxycarboxylic acids, or aromatic
242 ignificantly less sensitive to inhibition by dicarboxylic acids, indicating that Arg311 interacts wit
244 effect of ammonia on the partitioning of two dicarboxylic acids, oxalic (C2) and adipic (C6) is deter
245 le and could not utilize nitrate, urea, C(4)-dicarboxylic acids, several amino acids, or concentratio
246 hydroxidoplatinum(IV) precursors and various dicarboxylic acids, such as oxalic, malonic, 3-methylmal
247 ere, the evaporation behavior of mixtures of dicarboxylic acids, which are common atmospheric aerosol
248 ly results in formation of the corresponding dicarboxylic acids, which are further metabolized and en
249 ly results in formation of the corresponding dicarboxylic acids, which are further metabolized in the
250 predominantly allows sugars to be made from dicarboxylic acids, which are products of lipid breakdow
251 uated using C13-C18 monocarboxylic and C6-C8 dicarboxylic acids, which have vapor pressures at 25 deg
252 omega-oxidized to generate alpha-chlorinated dicarboxylic acids, which include alpha-chloroadipic aci
261 droxy forms, comparable in severity with the dicarboxylic aciduria of children with primary defects o
262 ic evaluation revealed fasting hypoglycemia, dicarboxylic aciduria, and reduced activity of the elect
263 ing state developed a distinctive and marked dicarboxylic aciduria, including saturated, unsaturated,
266 ines in PL2 and Ct and the presence of three dicarboxylic amino acids in PL2 appears to be necessary
268 which derive the short-chain carboxylic and dicarboxylic and the medium-chain fatty acids that have
270 ytotoxic effects of aluminum (Al) by exuding dicarboxylic and tricarboxylic acids that chelate and im
274 e desymmetrization of endo-norborn-5-ene-2,3-dicarboxylic anhydrides by methyl (S)-prolinate followed
275 dium-chain fatty acids, and higher levels of dicarboxylic fatty acids and 2-hydroxybutyrate (a known
280 uding short-chain, medium-chain, long-chain, dicarboxylic, hydroxylated, and unsaturated acyl moietie
282 tryptophan 140 were observed upon binding of dicarboxylic inhibitors to the pyridoxal 5'-phosphate (P
283 69 play key roles in specific recognition of dicarboxylic keto (prephenate) and amino (aspartate) aci
285 e chemical shift of bound [18-13C]-stearate; dicarboxylic/monocarboxylic acid cis-parinaric acid disp
286 including omega-phenylalkanoic, alpha,omega-dicarboxylic, omega-hydroxy, omega-1-oxo, omega-1-methyl
287 opanoic, p-toluic, and cis-pinonic acid) and dicarboxylic (oxalic, succinic, malic, adipic, and azela
289 h reacts only with the dianionic form of the dicarboxylic substrate, the R11A mutant reacts with both
290 ; it selectively disfavors interactions with dicarboxylic substrates and inhibitors compared to aroma
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