ライフサイエンスコーパス: dichotomous

1 However, chaperone effects on tau are dichotomous.

2 , further, that this interaction is sexually dichotomous.

3 In analyses using dichotomous 25(OH)D levels, values greater than or equal

4 roducibility of US results, using a standard dichotomous (absence/presence of synovitis) as well as a

5 challenge the classic experience/expression dichotomous account of emotions, according to which expe

6 The dichotomous action of nicotine resulted from the up- and

7 Dichotomous activation is assessed as the fraction of re

8 e (N=2547) and in independent samples with a dichotomous AG phenotype based on the Symptoms Checklist

9 Patients fell into two dichotomous age groups at the time of evaluation: six pa

10 servations suggest a different model for the dichotomous, age dependent outcome of HBV infection in h

11 seem to be much more multifarious than these dichotomous alternatives allow.

12 proteases of the chymotrypsin family show a dichotomous amino acid distribution for residue 225.

13 as used to calculate the effect size of both dichotomous and continuous data.

14 itative covariates and is applicable to both dichotomous and continuous phenotypes in various populat

15 evelopment of a fine-root pool that was less dichotomous and more exploratory under N-limited conditi

16 y to see the world of psychiatric illness in dichotomous and opposing terms has three major sources:

17 ysis was performed by using chi(2) tests for dichotomous and ordinal variables and the t test for con

18 ancies, suggesting that this complex plays a dichotomous and poorly understood role in cancer.

19 ethod is flexible and can be applied to both dichotomous and quantitative traits and allows for the i

20 he dichotomous trait, then joint analysis of dichotomous and quantitative traits should be more effic

21 rized each study using median risk ratio for dichotomous and standardized mean difference for continu

22 T family tests when the trait of interest is dichotomous and the sample size is small.

23 liability-threshold-model approach, standard dichotomous and/or qualitative disease phenotypes can be

24 ense heritability estimates for fatty liver (dichotomous) and fat fraction (continuous) were calculat

25 h, but also suggests complexities beyond the dichotomous approach of CLASH.

26 Both quantitative and dichotomous association analyses implicate a functional

27 These models differ in two dichotomous assumptions, constituting a 2 x 2 theoretica

28 Non-decremental, non-dichotomous backpropagation in AOB primary dendrites ens

29 Such dichotomous base-pairing behavior of the 5-azauracil moi

30 + channel currents were responsible for this dichotomous behavior, but the channels giving rise to th

31 nisms by which MSN subtype function promotes dichotomous behavioral outcomes caused by differences in

32 shares similarities with the nodal-antinodal dichotomous behaviour observed in underdoped copper oxid

33 The dichotomous behaviour of MITF in drug response is corrob

34 By differentiating between the two dichotomous biological activities of ANG, this strategy

35 ted nonparametric linkage (NPL) analyses for dichotomous BMI (using BMI >/=27, >/=30, >/=35, and >/=4

36 ion of downstream morphogens participates in dichotomous branching during prostate morphogenesis.

37 membrane domain associated with the repeated dichotomous branching of the hyphae.

38 del is that fixation and exploration are not dichotomous, but are instead two extremes of a functiona

39 rdinal NEC score and cut points to develop a dichotomous case definition based on the highest area un

40 The ordinal NEC score and dichotomous case definition discriminated well between i

41 Ordinal NEC likelihood score, dichotomous case definition, and GA-specific probability

42 We show that, together, these dichotomous cell types fulfil the requirements necessary

43 of COL4A3 expression than to result from the dichotomous change implied by the previously proposed ec

44 The analysis of the dichotomous change in clinical parameters over time reve

45 milar pseudogap state with a nodal-antinodal dichotomous character exists in a system that is markedl

46 A dichotomous choice for metazoan cells is between prolife

47 of the peripheral nerves, a straightforward, dichotomous classification scheme can be used in which t

48 no confidence) to 100 (totally confident) on dichotomous clinical judgements of critical event risk.

49 usual care in quality of depression care and dichotomous clinical outcomes (a decrease of at least 50

50 ges in infarct size, cardiac dimensions, and dichotomous clinical outcomes.

51 more powerful than either the continuous or dichotomous component in isolation, or a t-test on the z

52 aks in solid-state NMR indicates very stable dichotomous conformations for both the first and second

53 As a dichotomous covariate, COX-2 overexpression seemed to be

54 Although dichotomous criteria for the metabolic syndrome (MetS) a

55 y with central reviewing according to visual dichotomous criteria.

56 index (11-15%) using PASP as a continuous or dichotomous (cutoff=33 mm Hg) variable.

57 The placement and utility of dichotomous cutoffs might merit reconsideration.

58 An overall effect estimate for all dichotomous data as an odds ratio with 95% CI was calcul

59 Dichotomous data for induction of remission and continuo

60 We pooled dichotomous data to obtain relative risks of induction o

61 Dichotomous data were analyzed by random or fixed-effect

62 isk difference (RD) with 95% CI was used for dichotomous data; heterogeneity was assessed with the ch

63 e considers appropriate, instead of just the dichotomous decisions of whether to 'accept or reject th

64 Model-free linkage analyses, using a dichotomous definition for diabetic nephropathy in 397 s

65 sion as measured by decreased JSW or using a dichotomous definition of progression (joint space loss

66 For dichotomous definitions of periodontal disease, discrimi

67 s was performed with 'presence of DR' as the dichotomous dependent variable and other independent cov

68 was performed using treatment success as the dichotomous dependent variable controlling for independe

69 ss how index scores predicted continuous and dichotomous depression measures at 12, 18, and 24 months

70 Dichotomous dermatologic depictions of heroes and villai

71 nscription factor, which are consistent with dichotomous differentiation of SOX2-expressing precursor

72 g on mendelian randomization analyses with a dichotomous disease outcome and a continuous exposure.

73 Such a dichotomous distribution is not typically observed with

74 edictive of neuroblastoma disease outcome by dichotomous division of the neuroblastoma cohort.

75 alyses were performed after stratifying on a dichotomous education variable.

76 These findings help explain the dichotomous effect of smoking in patients with UC and CD

77 modulator) on the IL-2 promoter explain this dichotomous effect.

78 These findings illustrate the potential for dichotomous effects of a blocker in a long pore (with mu

79 In an attempt to explain recently reported dichotomous effects of E(2) in stroke injury, we tested

80 itself plays a central role in mediating the dichotomous effects of growth factor- and stress-stimula

81 ights into mechanisms that contribute to the dichotomous effects of Notch during development and tumo

82 Mechanistic investigations showed that the dichotomous effects of Nrf2 could be explained at least

83 These dichotomous effects of Stu2 are independent of its previ

84 f CD45-deficient and CD45 E613R mice reveals dichotomous effects of these mutations on B cell develop

85 These data indicate that RP105 does not have dichotomous effects on TLR4 signaling and emphasize the

86 infection by multivariate modeling with four dichotomous effects: mouse strain (A/J or C57BL/6), diet

87 We tested dichotomous end points by chi(2) test and NT-proBNP by M

88 We describe stereoselectively dichotomous enyne cycloisomerizations, entirely dependen

89 different lymphocyte subsets to produce this dichotomous eosinophilia or neutrophilia.

90 ia, the compulsion to perceive quantities as dichotomous even when dichotomization is unnecessary and

91 x proportional hazards regression model with dichotomous ever/never categorization.

92 determined from cross-product terms between dichotomous (ever/never) solvent variables and genotypes

93 For dichotomous exposures and outcomes, the typical 2-stage

94 rence estimates and that are appropriate for dichotomous exposures and outcomes.

95 of measures of additive interaction between dichotomous exposures, such as the relative excess risk

96 orphisms in IL1RL1 were found in relation to dichotomous expression of both ST2L and sST2.

97 jects were genotyped and the relationship of dichotomous expression of ST2L and sST2 to single nucleo

98 In yeast, genes exhibit dichotomous expression patterns based on their promoter

99 Here we show that microbially driven dichotomous faecal immunoglobulin-A (IgA) levels in wild

100 When using a dichotomous FFR value of 0.80, C statistic was significa

101 ed; mean values were largely consistent with dichotomous findings.

102 ied to null data generated by star-shaped or dichotomous four-taxon topologies.

103 n alternative perspective to the traditional dichotomous framework of ongoing and evoked activity.

104 The dichotomous function of EZH2 in regulating differentiati

105 ring experiments revealed that AR TAU5 had a dichotomous function, inhibiting ligand-dependent AR act

106 mation remain elusive because Notch displays dichotomous functional activities, promoting both prolif

107 clusion, our data support the concept that a dichotomous functional organization, as actioned by arky

108 l model that helps to explain the strikingly dichotomous functionality of MSCs in inflammation and im

109 f SIRTs in cancer is extremely complex, with dichotomous functions depending on cell contexts.

110 n tumor suppression and promotion, and these dichotomous functions have frustrated the development of

111 Collectively, current study elucidated dichotomous functions of BTLA in GVHD to serve as a cost

112 The dichotomous functions of TGF-beta are proposed to be dic

113 nts in cancer that are associated with these dichotomous functions.

114 these findings reveal a trait with markedly dichotomous functions.

115 The cutoff scores for the dichotomous GA-specific case definition were 2 or greate

116 al molecular-genetic evidence supporting the dichotomous grouping of sarcomas into those with charact

117 d interleukin 8 (IL-8) were compared between dichotomous groups with low or high serum 25(OH)D concen

118 ntinuous blood pressure were associated with dichotomous hypertension.

119 Generally, it is unknown why such dichotomous immune responses occur between humans and re

120 endent mechanism through which gp96 controls dichotomous immune responses relevant to the therapy of

121 on analyses, both large and small, have been dichotomous in nature, in which phenotypes are compared

122 Although these physiologic roles are truly dichotomous in terms of functional end point, mechanisti

123 Medium spiny neurons (MSNs) in striatum are dichotomous in their expression of either D1 or D2 dopam

124 ase on a simple additive scale composed of 9 dichotomous independent variables multiplied the odds ra

125 Dichotomous indicator for counties with at least 1 outpa

126 Dichotomous indicators for whether a zip code tabulation

127 (Liebowitz Social Anxiety Scale (LSAS)) and dichotomous indicators of response (LSAS </= 50) and rem

128 In dichotomous indices of therapeutic response, a significa

129 Dichotomous interreader reliability (kappa) for the enti

130 Dichotomous keys that follow a single pathway of charact

131 Such dichotomous kinetics implicate additional rate-limiting

132 s of TKI resistance have been viewed under a dichotomous lens.

133 ic regression, (2) homogeneity tests, or (3) dichotomous logistic regression, analyzing all 7 possibl

134 racellular and intracellular equilibria in a dichotomous manner that both endangers cells and defends

135 FITs are invariably used in a dichotomous manner using pre-specified cut-off values.

136 and the ER is currently used clinically as a dichotomous marker.

137 The primary antimicrobial outcome was a dichotomous measure (<15 colony-forming units or >/= 15

138 over the subsequent 4 years compared with a dichotomous measure in middle-aged and older adults.

139 n was treated as a continuous, rather than a dichotomous, measure and when controlling for age and st

140 correlated across all diagnostic groups, and dichotomous measurements were in agreement in 86% of sub

141 18 months, and P < 0.001 for 24 months) and dichotomous measures (P < 0.05 for 18 and 24 months).

142 These results demonstrated dichotomous mechanisms by which IL-15 regulated lymphoid

143 A dichotomous method was also developed to enable rapid de

144 trical flow distributions at bifurcations in dichotomous microvascular networks.

145 The authors identified eight dichotomous Minnesota Code criteria that provided a cons

146 Simulated scenarios focused on continuous or dichotomous missing outcome data from randomized trials

147 A predefined dichotomous model classified tumors as "high expressor"

148 Over the past decade, this strictly dichotomous model of transmembrane signaling has been ch

149 ms that cannot be appropriately modeled by a dichotomous model; the subjects in a study may be recrui

150 ge and motor composite scores, growth, and a dichotomous mortality and morbidity index.

151 and steatohepatitis, two states with fairly dichotomous natural history.

152 The dichotomous nature of Gal-9 is evident in hepatocellular

153 The dichotomous nature of metabolic syndrome criteria and la

154 asi-likelihood framework, which exploits the dichotomous nature of the trait and achieves computation

155 t compensated for, which may account for the dichotomous nature of this farming symbiosis.

156 es to climate change are often guided by the dichotomous needs to resolve either (i) internal plant w

157 enescence checkpoint functions may influence dichotomous Notch activities in the neoplastic context.

158 experimental approach, that these apparently dichotomous observations can simply result from a single

159 These dichotomous observations challenge our thinking about ho

160 rong relationship when volume is tested as a dichotomous or categorical variable.

161 Dichotomous, or even opposing, functions have been descr

162 es in rats to determine whether and how this dichotomous organization applies to the dopamine-intact

163 at GPe exhibits several core components of a dichotomous organization as fundamental as that in stria

164 evels were examined as both a continuous and dichotomous outcome (using a threshold of 130 mg/dL).

165 In contrast to the commonly used dichotomous outcome FA vs no FA, the allergy status is i

166 and (3) reported a statistically significant dichotomous outcome in the abstract.

167 etermine the statistical power of predefined dichotomous outcome measures (termed "a priori"), compar

168 sh-language trials and could not incorporate dichotomous outcome measures into the analysis.

169 he effects of all independent variables on a dichotomous outcome recurrence in relation to time.

170 on model for pain exacerbation measured as a dichotomous outcome variable, and a mixed-effects regres

171 prenatal urinary BPA concentration with the dichotomous outcome wheeze (wheeze over the previous 6 m

172 A probabilistic model of each dichotomous outcome, derived using a stepwise Bayesian p

173 To demonstrate the application of ISM with a dichotomous outcome, we prospectively examined the assoc

174 t and term or preterm (<37 weeks) birth as a dichotomous outcome.

175 juries were modeled using SEM procedures for dichotomous outcomes and a complex sampling design.

176 M is a useful approach with which to examine dichotomous outcomes and indirect effects in complex sam

177 We pooled risk ratios of dichotomous outcomes and mean differences of continuous

178 in meta-analyses, reporting odds ratios for dichotomous outcomes and standardized mean differences f

179 The dichotomous outcomes are related directly to the distinc

180 these are not the primary forces behind the dichotomous outcomes observed but reveal a limited capac

181 For dichotomous outcomes, the authors discuss when the stand

182 For dichotomous outcomes, we entered the number of events an

183 Odds ratios (ORs) were pooled for dichotomous outcomes, with all-cause mortality as the pr

184 table for serial monitoring of continuous or dichotomous outcomes.

185 Second, a superordinate, dichotomous pattern of activation/deactivation, is commo

186 A similar dichotomous pattern of association or exclusion describe

187 rongly symptom-provoking conditions evoked a dichotomous pattern of deactivation/activation in patien

188 We observed a dichotomous pattern of PKM expression, in which postmito

189 found that metastatic melanomas exhibit two dichotomous patterns of gene expression, which unexpecte

190 ciated with SC were also associated with the dichotomous phenotype, DSM-IV AD.

191 ly using a mixed model approach to partition dichotomous phenotypes into additive risk and non-additi

192 ach was used: (1) a mixed model to partition dichotomous phenotypes into an additive component and no

193 bilistic model to predict the probability of dichotomous phenotypes.

194 gnitive decline that is not available from a dichotomous positive/negative categorization.

195 lihood ratios can be calculated not only for dichotomous (positive or negative) tests but also for te

196 ch outcome, physicians and nurses provided a dichotomous prediction and rated their confidence in tha

197 iscal position factor and meniscal damage as dichotomous predictors in each model) on cartilage loss

198 obing depth (PD), clinical attachment level, dichotomous presence or absence of supragingival plaque

199 dmission serum creatinine was categorized as dichotomous (presence of CKD as <60) or as distinct cate

200 cytes (CTLs) is typically considered to be a dichotomous process and uncommon during chronic HIV-1 in

201 ity approach therefore identified apparently dichotomous processes characterizing the amyotrophic lat

202 bias were identified that not only manifest dichotomous protein expression but also are enriched in

203 In response to a dichotomous question, 37% of parents supported testing m

204 In response to a dichotomous question, 44% of parents reported hypothetic

205 The STEPP contains 4 dichotomous questions asked of the child, 4 asked of one

206 , comparisons between summary scores for the dichotomous questions between the CLE cases and non-CLE

207 tron emission tomography scan is to assign a dichotomous rating of positive or negative for the prese

208 data provide a molecular explanation for the dichotomous regulatory activities of Soj, as well as ass

209 However, it displays a dichotomous requirement for initiation site selection be

210 This dichotomous response in CD8+ T cell response may in part

211 dar hypomorph is paralleled by an unexpected dichotomous response of ADAR target transcripts, i.e. ce

212 The mechanisms responsible for the dichotomous response of neonatal and adult CD161(hi) cel

213 The dichotomous response of the mutants to the carotenoids i

214 at naive CD4+ T cells from DBA/1 mice have a dichotomous response to TGFbeta: enhanced RORgammat, yet

215 Critically, this dichotomous response was associated with enhanced regula

216 n by clinically relevant genetic changes but dichotomous responses to hormonal therapy, we show that

217 dels, together with longitudinal modeling of dichotomous responses.

218 thalmology trials, statistically significant dichotomous results are often fragile, meaning that a di

219 menology of photic integration and suggest a dichotomous retinohypothalamic network leading to circad

220 is proposed to identify patterns of multiple dichotomous risk factors for outcomes of interest in gen

221 Together, our data describe a dichotomous role for ATF3-mediated regulation of neutrop

222 lleagues in this issue of Neuron describes a dichotomous role for the activator protein p25 in synapt

223 This study identifies a novel dichotomous role for TLR4 as a growth regulator and a mo

224 pericytes in neovascularization and reveal a dichotomous role for VEGF and VEGF-R2 signalling as both

225 Natural killer (NK) cells play a dichotomous role in alloimmune responses because they ar

226 B cells have a dichotomous role in both the pathogenesis and recovery f

227 Autophagy serves a dichotomous role in cancer and recent advances have help

228 We present evidence that ATF3 has a dichotomous role in cancer development.

229 In summary, this study shows that Pfn1 has a dichotomous role in early vs late steps of breast cancer

230 rmore, we demonstrated that KDM2B exhibits a dichotomous role in hematopoietic malignancies.

231 Thus, autophagy plays a dichotomous role in this model of disease.

232 Marcus theory may explain the dichotomous role of exciting the donor or the acceptor o

233 Here we report a dichotomous role of megakaryocytes (MKs) in both maintai

234 were both driven by IFN-gamma, revealing the dichotomous role of this cytokine in regulating IL-12-me

235 Here, we will review in detail the dichotomous role of TLRs in tumor biology, focusing on r

236 Thus, we have investigated the potential dichotomous role of YAP in UCC response to chemotherapy

237 MOylation-based mechanism controlling WASp's dichotomous roles in transcription may have implications

238 tor cells, yet how this pathway serves these dichotomous roles remains enigmatic.

239 Dichotomous root branching in Selaginella appears to be

240 ground radiation both in analyses based on a dichotomous score and in analyses of continuous scores o

241 olecular-genetic aspects of the evolution of dichotomous sexes.

242 Understanding the mechanisms behind this dichotomous signalling is an important area of molecular

243 iscuss the signal pathways that mediate this dichotomous signalling, and the factors that influence w

244 ly homogenous population, striatal MSNs have dichotomous somatodendritic properties that mirror diffe

245 This dichotomous spatial organization is especially pronounce

246 This suggests that applying a dichotomous-stage diagnosis on the basis of CSF pleocyto

247 To model dichotomous states of persistent Ag exposure in the pres

248 calins and 7,6-bicycles can be obtained with dichotomous stereochemical outcomes.

249 e the view that exploration and fixation are dichotomous, suggesting instead that visual fixation is

250 Here, subnetworks are defined using serial dichotomous suppression and enforcement of flux through

251 he Pediatric Risk of Mortality III score) in dichotomous (survival and death) and trichotomous (survi

252 cterized Scl1 proteins of S. pyogenes show a dichotomous switch in ligand binding between human tissu

253 n even when the null data are generated by a dichotomous topology.

254 of 0.73 was estimated considering deafness a dichotomous trait and 0.75 considering it as a trichotom

255 er family members rather than a qualitative, dichotomous trait and comparing probands with the health

256 studies have focused on the situation when a dichotomous trait can be modeled by a threshold process

257 on to solving the classification problem for dichotomous trait disease models, our results apply to a

258 Sib pair linkage analysis of a dichotomous trait is a popular method for narrowing the

259 Standard linkage scans using hoarding as a dichotomous trait were also performed by using GENEHUNTE

260 on and rare) in a region and a continuous or dichotomous trait while easily adjusting for covariates.

261 ked to the chromosomal regions linked to the dichotomous trait, then joint analysis of dichotomous an

262 protein-coding genes with a quantitative or dichotomous trait.

263 y complex diseases are usually considered as dichotomous traits but are also associated with quantita

264 ood-based variance decomposition extended to dichotomous traits implemented in the computer package S

265 For such dichotomous traits, although their associated quantitati

266 in the offspring and to the estimation, for dichotomous traits, of the relative contribution of gene

267 sis increases the power to detect linkage of dichotomous traits.

268 is known only for continuous traits and for dichotomous traits.

269 small, especially for the important case of dichotomous traits.

270 MECP2 is a dichotomous transcription regulator that either activate

271 g an AhR agonist-specific mutually exclusive dichotomous transcriptional response.

272 sease control rate (DCR; CR/PR/SD v PD), and dichotomous tumor response (DiTR; CR/PR v others) metric

273 elated with survival, the impact of a single dichotomous value to predict outcomes was limited.

274 ous basis given limited ability of a single, dichotomous value to predict outcomes.

275 different ways: as a continuous variable, a dichotomous variable (above and below the Leapfrog thres

276 examined as both a continuous variable and a dichotomous variable (above or below the median decrease

277 able using cumulative logit regression, as a dichotomous variable (excellent/very good/good versus fa

278 was analyzed as a continuous variable and a dichotomous variable (higher albumin excretion, includin

279 ed vigorous physical activity primarily as a dichotomous variable (inactive [rarely/never] versus act

280 Hypertension, treated as a dichotomous variable (yes/no), was defined as a systolic

281 outcomes, most studies have treated it as a dichotomous variable based on academic credentials.

282 oportional hazards model, incorporation of a dichotomous variable by defining hypertension as CBP >/=

283 tic-regression analysis, with the use of the dichotomous variable of a tricuspid regurgitant jet velo

284 Analysis of donor age as a dichotomous variable showed that donors greater than 60

285 Similar model with V-wave change as a dichotomous variable showed that patients with a V-wave

286 e number of positive findings and deriving a dichotomous variable to approximate the top quintile ("h

287 For abdominal obesity, a dichotomous variable was created: 1) eutrophic/lost weig

288 action between use of sunitinib and age as a dichotomous variable was highly significant (P = 0.003).

289 ornell product was entered as a time-varying dichotomous variable, a greater-than-median in-treatment

290 (RR) and 95% confidence intervals (CIs) for dichotomous variables and as standardized mean differenc

291 Dichotomous variables were analyzed by chi2 test and con

292 ontinuous distributions that are analyzed as dichotomous variables.

293 ent between 1.5 T and 3.0 T on compositional dichotomous variables.

294 ence of VAP and mortality were abstracted as dichotomous variables.

295 e of past and acute herpesvirus infection as dichotomous variables.

296 A dichotomous vascular construct was created from the pres

297 This dichotomous view is buoyed by the high expression of alp

298 constructs, and critically examines both the dichotomous view of learning as well as the claim that l

299 At the same time, a dichotomous view that separates noncognitive, unconsciou

300 hagoletis, reconciling some of the seemingly dichotomous views of Mayr, Dobzhansky, and Bush concerni