ライフサイエンスコーパス: dieldrin

1 BAA antagonist (bicuculline or the pesticide dieldrin).

2 e that confers resistance to the insecticide dieldrin.

3 y; however, a suggestive finding emerged for dieldrin.

4 etic mapping of resistance to the cyclodiene dieldrin.

5 e.g., DDT in the western part of Germany and dieldrin.

6 ncrease in basal [Ca(2+)](i) is inhibited by dieldrin.

7 of these two agents than of chlorpyrifos and dieldrin.

8 rgic neuronal degeneration after exposure of dieldrin.

9 ate both receptors, such as clotrimazole and dieldrin.

10 (GABA) receptor subunit gene, Resistance to dieldrin.

11 ing gestation and lactation to low levels of dieldrin (0.3, 1, or 3 mg/kg every 3 days) alters dopami

12 or pendimethalin (1.50; 95% CI: 0.98, 2.31), dieldrin (1.93; 95% CI: 0.70, 5.30), and chlorimuron eth

13 veloped resistance to insecticides including dieldrin, 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane

14 ns, which were countered by bicuculline (and dieldrin, 5-HT neurons only).

15 Dieldrin, a highly persistent organochlorinated pesticid

16 In this paper we describe the effect of dieldrin and a binary mixture of dieldrin and lindane on

17 The combined findings indicate that dieldrin and binary mixtures of organochlorines affect [

18 e effect of dieldrin and a binary mixture of dieldrin and lindane on a critical parameter of neuronal

19 Co-exposure of PC12 cells to a mixture of dieldrin and lindane revealed an additive inhibition of

20 Surprisingly, the effects of diazinon, dieldrin and Ni(2+) showed basic similarities despite th

21 ike, whereas there was strong concordance of dieldrin and Ni(2+) with each other and with each indivi

22 orpyrifos, diazinon) with an organochlorine (dieldrin) and a metal (Ni(2+)) for similarities and diff

23 (chlorpyrifos, diazinon), an organochlorine (dieldrin) and a metal (Ni(2+)) for their effects on neur

24 (chlorpyrifos, diazinon), an organochlorine (dieldrin) and a metal (Ni(2+)); we utilized microarrays

25 polychlorinated biphenyls, DDTs, chlordanes, dieldrin, and alpha- and gamma-hexachlorocyclohexane (HC

26 Gaseous concentrations of hexachlorobenzene, dieldrin, and chlordanes were significantly greater (Man

27 400 and -200 (pg.m(-2).d(-1)) for gamma-HCH, dieldrin, and chlorpyrifos, respectively.

28 ce for an association between pendimethalin, dieldrin, and parathion use and lung cancer risk.

29 id (2,4,5-T); the organochlorine insecticide dieldrin; and the organophosphate insecticides diazinon,

30 The halving times for DDTs, chlordanes, and dieldrin are 8.7 +/- 0.4 years for both the atmosphere a

31 ctures such as diazinon, heptachlor, endrin, dieldrin, butachlor and chlordane.

32 demonstrate that nanomolar concentrations of dieldrin can stimulate microglia to produce ROS that may

33 ropionic acid (2,4,5-TP) and possibly use of dieldrin, captan, and 2,4,5-trichlorophenoxyacetic acid

34 Elevated levels of dieldrin, chlordane- and DDT-related pesticides, polycyc

35 Dissolved SigmaHCH and dieldrin concentrations decreased linearly with increasi

36 ors (TN, CN), heptachlor exo-epoxide (HEPX), dieldrin (DIEL), chlorobornanes (SigmaCHBs and toxaphene

37 nazine, picloram, aldicarb, azinphos-methyl, dieldrin, diquat dibromide, endosulfan, and esfenvalerat

38 of two weak environmental estrogens, such as dieldrin, endosulfan, or toxaphene, were 1000 times as p

39 a greater reduction of striatal dopamine in dieldrin-exposed offspring, which was associated with a

40 Additionally, dieldrin exposure during development potentiated the inc

41 porter 2 (VMAT2) were increased by perinatal dieldrin exposure in a dose-related manner.

42 istone acetylation occurred within 10 min of dieldrin exposure indicating that acetylation is an earl

43 of microglial cells with 0.1 nM to 1 microM dieldrin for 24 h resulted in a concentration-dependent

44 receptors, and overlap between diazinon and dieldrin for the receptors led to a stronger resemblance

45 The Resistance to Dieldrin gene, Rdl, encodes a GABA-gated chloride channe

46 d by reduced dosage of the Rdl (Resistant to dieldrin), gene encoding a subunit of inhibitory GABA re

47 However, dieldrin had more notable effects on neuropeptide recept

48 chlorine (OC) insecticides lindane (HCH) and dieldrin (HEOD) to the development of neurodegenerative

49 dichlorodiphenyltrichloroethane (p,p -DDT), dieldrin, heptachlor epoxide, HCB, trans-nonachlor, oxyc

50 Furthermore, 30-day exposure of dieldrin in mouse models induced histone hyperacetylatio

51 n addition to immortalized microglial cells, dieldrin induced a concentration-dependent ROS generatio

52 n mesencephalic dopaminergic neuronal cells, dieldrin induced a time-dependent increase in the acetyl

53 tment on histone acetylation and its role in dieldrin-induced apoptotic cell death in dopaminergic ne

54 itor anacardic acid significantly attenuated dieldrin-induced histone acetylation, Protein kinase C d

55 Furthermore, the dieldrin-induced microglial ROS generation was significa

56 The dieldrin-induced microglial ROS generation was time-depe

57 mation on the potential role of microglia in dieldrin-induced neurodegeneration in relevance to the d

58 The hyperacetylation was attributed to dieldrin-induced proteasomal dysfunction, resulting in a

59 te that exposure to the neurotoxic pesticide dieldrin induces acetylation of core histones because of

60 n particular, the organochlorine insecticide dieldrin is believed to be associated with PD.

61 data suggest that developmental exposure to dieldrin leads to persistent alterations of the developi

62 ion of the organochlorine pesticides aldrin, dieldrin, lindane, and alpha-endosulfan by using surface

63 Compared with those in the lowest quintile (dieldrin, < 0.57 mug/L), odds of obesity were 3.6 (95% C

64 des (desulfinylfipronil, AMPA, chlorpyrifos, dieldrin, metolachlor, atrazine, CIAT, glyphosate) and t

65 n Vallee du Kou (VK) to pyrethroids, DDT and dieldrin, moderate level for carbamates and full suscept

66 cating that acetylation is an early event in dieldrin neurotoxicity.

67 study, we set out to determine the effect of dieldrin on the production of ROS and the underlying mec

68 With the exception of dieldrin, our data shows PCBs and other organochlorine p

69 effects on both 5-HT and TH neurons, whereas dieldrin potently inhibited 5-HT neurons only.

70 acid decarboxylase 1 (Gad1) and Resistant to dieldrin (Rdl), genes vital for GABAergic neurotransmiss

71 n of the GABA(A) receptor gene, Resistant to dieldrin (Rdl), in PDF neurons reduces sleep, consistent

72 The GABAA receptor, resistance to dieldrin (Rdl), is highly expressed in the Drosophila mu

73 teracts with the GABAA receptor Resistant to Dieldrin (RDL), upregulating its levels and promoting it

74 le point mutations in the gene Resistance to dieldrin (Rdl), which codes for a subunit of a gamma-ami

75 t from Drosophila melanogaster [Resistant to Dieldrin (RDL)] has been cloned, functionally expressed,

76 rdance between Ni(2+) and either diazinon or dieldrin, reflecting similarities toward the receptors.

77 o includes a biochemical selectable markers, Dieldrin resistance (Dl), on the second chromosome and f

78 s with this duplication exhibit intermediate dieldrin resistance compared with single copy Ser(301) h

79 strong correlation with pyrethroids/DDT and dieldrin resistance.

80 Surprisingly, dieldrin shared many of the same neuropeptide targets as

81 ic samples; however, some compounds (such as dieldrin) showed reduced concentrations from 7.5-3.4 to

82 ptors is constructed from RDL (resistance to dieldrin) subunits from Drosophila melanogaster.

83 whereas losses exceeding 80% were found for dieldrin, sulfotep or phorate.

84 d among users of the chlorinated insecticide dieldrin, the fumigant mixture carbon-tetrachloride/carb

85 demonstrate that nanomolar concentrations of dieldrin time- and concentration-dependently inhibit dep

86 The most commonly detected pesticides were dieldrin, trans-chlordane, endosulfan I, and chlorpyrifo

87 In this study, we examined the effects of dieldrin treatment on histone acetylation and its role i

88 observed in cells 12-24 h, but not 6 h after dieldrin treatment.

89 Aldrin and dieldrin were less potent than endrin in interfering wit

90 nochlorine pesticides, the most abundant was dieldrin, with the highest average concentration of 99 +