ライフサイエンスコーパス: diencephalic

1 Tumors were infratentorial (102), diencephalic (53), and hemispheric (39); 47% required ve

2 el insights into the functional pathology of diencephalic amnesia and have implications for the aetio

3 lationship between temporal lobe amnesia and diencephalic amnesia depends on determining the role of

4 While most accounts of diencephalic amnesia emphasize the functional importance

5 r, the reasons for the severe memory loss in diencephalic amnesia remain unknown.

6 primary sites of neuropathology in cases of diencephalic amnesia such as Wernicke Korsakoff Syndrome

7 A rodent model of diencephalic amnesia, pyrithiamine-induced thiamine defi

8 the anterior thalamic nuclei at the heart of diencephalic amnesia.

9 tion, Phox2a(+) neurons were observed within diencephalic and brainstem nuclei that regulate behavior

10 Significant increases in diencephalic and brainstem serotonin transporter binding

11 The purpose of this study was to identify diencephalic and brainstem sites active during exercise

12 etwork linking ventral striatal opioids with diencephalic and brainstem structures.

13 selectively affected mesencephalic cultures; diencephalic and C6 glioma cells were not affected by DA

14 effect on any parameters examined in primary diencephalic and C6 glioma cultures.

15 (ii) Do temporal lobe, diencephalic and frontal lobe amnesias differ?

16 and cognition seems reflected in reciprocal diencephalic and limbic activation with solvable and uns

17 studies have implicated the majority of the diencephalic and mesencephalic nuclei in electrosensory,

18 enes to be induced by FGF8 in wild-type E9.5 diencephalic and midbrain explants treated with FGF8-soa

19 drome spectrum with the first description of diencephalic and striatal neuropathology.

20 Diencephalic and telencephalic astrocytes, from both chi

21 he anterior neural plate into telencephalic, diencephalic, and eye-forming territories.

22 by transplanting dissociated telencephalic, diencephalic, and mesencephalic cells of E14 mouse embry

23 dendrocytes incorporated into telencephalic, diencephalic, and mesencephalic regions and assumed phen

24 re frequently the cerebellum, brainstem, and diencephalic areas.

25 ich temporal lobe seizures disrupt brainstem-diencephalic arousal systems, leading indirectly to depr

26 propagation were abolished by melatonin, as diencephalic astrocytes acquired more telencephalon-like

27 Diencephalic astrocytes are sites of action, at least in

28 stimulated an increased number of fetal rat diencephalic astrocytes to progress through G1/S, and th

29 However, waves meandered among mouse diencephalic astrocytes, taking heterogeneous paths at v

30 imilar to the 23% increase observed in chick diencephalic astrocytes.

31 Mouse diencephalic astrocytic calcium waves spread to an area

32 to the dMT, including brainstem, cerebellar, diencephalic, basal ganglia, and cortical regions involv

33 recommand nucleus (PCN) at the mesencephalic-diencephalic border and the ventroposterior nucleus (VP)

34 ventral telencephalic domain adjacent to the diencephalic border.

35 s that occupied only a part of certain inter-diencephalic boundaries, fiber tracts were present withi

36 ble for formation of an intact telencephalic-diencephalic boundary and for preventing the abnormal po

37 ssion in thalamus and prethalamus, the major diencephalic brain areas flanking the ZLI.

38 However, the ontogeny of these diencephalic brain nuclei has not to this date been exam

39 Regional differences in diencephalic cell density were lost, the diencephalon/me

40 subthalamic nucleus (STN) is a glutamatergic diencephalic cell group that develops in the caudal hypo

41 by tracing the afferent connectivity of this diencephalic cell population.

42 cephalon) revealed a unique role for Isl1 in diencephalic cells bordering the internal capsule for th

43 d for preventing the abnormal positioning of diencephalic cells in the dorsal telencephalon.

44 nule cells share a lineage with cortical and diencephalic cells, pointing toward a common lineage tha

45 We observed occasional cells with diencephalic character in the Foxg1 (forkhead box)-expre

46 As described previously, the diencephalic complex of the central posterior thalamic n

47 dentified for the forebrain and midbrain and diencephalic components of the ascending auditory pathwa

48 may compensate for inefficient corticolimbic-diencephalic components.

49 rise within a contiguous field separate from diencephalic CPe, also exhibited different patterns of a

50 is also early posterior cingulate cortex and diencephalic damage.

51 Diencephalic defects underlie an array of neurological d

52 unction, but those with additional limbic or diencephalic deficits were most affected; 60% of these p

53 retinoic acid (RA) signaling is involved in diencephalic development at late stages of embryonic dev

54 r normal Pax-6 protein is required for early diencephalic development by examining morphology, precur

55 ain) was disrupted, supporting the idea that diencephalic development is abnormal from very early in

56 role for both GCN5 and RA signaling in early diencephalic development, and elucidate a novel molecula

57 Pax-6 may also control some aspects of diencephalic differentiation, but its mutation in Small-

58 xpression in the ZLI alone is sufficient for diencephalic differentiation.

59 a, confining expression to a discrete dorsal diencephalic domain.

60 otpb gene that drove specific expression in diencephalic dopaminergic neurons, although it did not s

61 ctum, and pituitary are the major targets of diencephalic dopaminergic neurons.

62 all patients and 89% of those with limbic or diencephalic dysfunction.

63 a 63-year-old man with clinical criteria for diencephalic encephalitis with sleepiness, cataplexy, hy

64 Last, we demonstrate that the diencephalic expansion and transcriptional defects seen

65 exencephalic phenotype, exhibit significant diencephalic expansion, decreased diencephalic RA signal

66 Diencephalic explants from transgenic mice expressing en

67 Later in embryogenesis its diencephalic expression becomes more restricted.

68 we show that Shh/Gli2 signaling controls the diencephalic expression of Bone morphogenetic protein 4

69 .5 Small-eye mice revealed discrete zones of diencephalic expression that had similar relative positi

70 and telencephalon are reduced or absent and diencephalic fates expand to the front of the brain.

71 Hypothalamic and diencephalic groups were detected and, in particular, th

72 The connectivity between diencephalic gustatory centers and the telencephalon was

73 for memory, and consequently indicates that diencephalic-hippocampal models of memory should be exte

74 onal hormonal or MRI abnormalities indicated diencephalic-hypothalamic involvement in 34% of the pati

75 chus, the dorsolateral pallium (DL) receives diencephalic inputs representing electrosensory input ut

76 cephalon and diencephalon, the telencephalic/diencephalic junction (TDJ), is often indistinct, and th

77 te transections of the neuroaxis at the meso-diencephalic juncture.

78 expression in the brain, we find that early diencephalic left-right asymmetry also requires Southpaw

79 southpaw, that is required for visceral and diencephalic left-right asymmetry.

80 akoff syndrome (WKS) culminates in bilateral diencephalic lesion and severe amnesia.

81 ne deficiency (PTD), was used to investigate diencephalic-limbic interactions.

82 complete resection (OR = 15.50, p = 0.0009), diencephalic location (OR = 12.2, p = 0.013), and high-g

83 ions of the NPY and LHRH systems may involve diencephalic loci.

84 These findings support models of diencephalic memory mechanisms that require hippocampal

85 ula, preglomerular nuclei, and several other diencephalic, mesencephalic, and rhombencephalic regions

86 g a "subcortical visual shell" overlying the diencephalic-mesencephalic border.

87 ransfer, we show that the positioning of the diencephalic-mesencephalic boundary (DMB) requires Engra

88 no obvious alterations in expression at the diencephalic midline.

89 However, the mechanisms that regulate diencephalic morphogenesis and the involvement of RA sig

90 In Small-eye mice, diencephalic morphology was abnormal at all the embryoni

91 ur findings strongly suggest activation of a diencephalic network that participates in behavioral res

92 basal hypothalamic regions, and the distinct diencephalic neuromeres could be analyzed on the basis o

93 ic system is the orthopedia (otp)-expressing diencephalic neuronal population that constitutes the do

94 primate mammalian species, telencephalic and diencephalic neurons originate from their respective loc

95 n thyrotropin-releasing hormone in fetal rat diencephalic neurons, their localization and transcripti

96 To broaden our understanding of diencephalic NMDA-R participation in other functions, we

97 with holoprosencephaly in humans, regulates diencephalic Nodal activity during initial establishment

98 subdivisions and nucleus taenia); (2) other diencephalic nuclei (centroposterior, glomerular, and an

99 The right habenula and posterior tuberculum (diencephalic nuclei) receive convergent inputs from rest

100 l complex differentially influences adjacent diencephalic nuclei, the left and right habenulae, which

101 anesthetics act on one or more brainstem or diencephalic nuclei, with suppression of cortex and spin

102 subpallial telencephalic areas, and in some diencephalic nuclei.

103 any more cells are present in DL than in the diencephalic nucleus that provides it with sensory input

104 concentrated in and along the margins of the diencephalic optic tract and essentially absent from its

105 se superficially in the middle stream of the diencephalic optic tract.

106 presented with isolated or combined limbic, diencephalic or brainstem dysfunction, and four with oth

107 should be suspected in patients with limbic, diencephalic or brainstem dysfunction, MRI abnormalities

108 ow-up, 95% of the patients developed limbic, diencephalic or brainstem encephalopathy.

109 tes of isolated hypothalamic, but not dorsal diencephalic or cerebellar cells.

110 The unexpected extra-diencephalic origin of dLGN-INs sets them apart from GAB

111 However, the major afferents to the Vv were diencephalic, particularly those originating from the ro

112 s specifically related to early-stage limbic-diencephalic pathology, and that non-mnemonic impairment

113 y both unique and redundant functions during diencephalic patterning.

114 ed in isthmal (nucleus praeeminentialis) and diencephalic (posterior thalamic) nuclei.

115 -6 is required for the correct regulation of diencephalic precursor proliferation.

116 ted to both retinas, bordered posteriorly by diencephalic precursors expressing mariposa.

117 e that movement of a median subpopulation of diencephalic precursors separates retinal precursors int

118 trula including prechordal plate and ventral diencephalic precursors.

119 t the main route of transmission consists of diencephalic (preglomerular complex; PG) glutamatergic i

120 environment and anatomical deficiency in the diencephalic preoptic area, where the optic chiasm norma

121 ects on these cells; the inputs from the two diencephalic prepacemaker nuclei, PPnC and PPnG, which r

122 WNT7b is expressed in cerebral cortical and diencephalic progenitor cells.

123 While diencephalic progenitors from R-cadherin-expressing regi

124 Furthermore, diencephalic progenitors that integrate heterotopically

125 omplex retroviral library was used to infect diencephalic progenitors.

126 cal TH-ir neurons but may include input from diencephalic projections as well.

127 We estimated diencephalic proliferative rates after labelling with br

128 d the alar hypothalamus, and caudally by the diencephalic prosomere p3.

129 ignificant diencephalic expansion, decreased diencephalic RA signaling, and increased diencephalic WN

130 ation of transitin mRNA is best shown in the diencephalic radial glia, as well as cerebellar Bergmann

131 es synthesis of methionine enkephalin in the diencephalic region of the brain.

132 ificant progress in the comprehension of the diencephalic region of Xenopus and show that the organiz

133 not preclude the development of a degree of diencephalic regionalization resembling that in normal m

134 y, suggesting that Bhlhb4 may have a role in diencephalic regionalization.

135 is double dissociation shows that the limbic-diencephalic regions damaged in amnesia and the neostria

136 mu-receptor mRNA was expressed in different diencephalic regions including the preoptic area, the be

137 acquisition of identity for these important diencephalic regions.

138 ng of limbic forebrain regions from midbrain/diencephalic regions.

139 tes at a left-to-medial site from the dorsal diencephalic roof, becomes displaced in position.

140 amus and dorsal thalamus, and functions as a diencephalic signaling center.

141 E, and that characteristic telencephalic and diencephalic signaling centers, the cortical hem and zon

142 evelopment.SIGNIFICANCE STATEMENT Changes in diencephalic size and shape, as well as SNPs associated

143 of RA signaling that is required to restrict diencephalic size during early forebrain development.SIG

144 en despite the absence of medial temporal or diencephalic strokes.

145 The habenula is a dorsal diencephalic structure consisting of medial and lateral

146 d herald a new understanding of why specific diencephalic structures are vital for memory.

147 it2 expression is strong in anterior ventral diencephalic structures but is absent from the ventral m

148 the neuroanatomy of medial temporal lobe and diencephalic structures important for memory, multiple m

149 ield into diencephalic territory and loss of diencephalic structures, indicating a role for Rtk1 in p

150 mRNAs showed substantial enrichment in basal diencephalic structures, particularly the hypothalamus,

151 ates, its expression is enriched in specific diencephalic structures, where the highest levels are ob

152 lary bodies, components of the corticolimbic-diencephalic subsystem subserving functionally later dev

153 ty of components of the extended hippocampal-diencephalic system to memory performance in MS patients

154 leus of channel catfish project to different diencephalic targets, single cells were intracellularly

155 mispositioned and appeared to arise from the diencephalic-telencephalic boundary.

156 1-positive telencephalic- and Foxg1-negative diencephalic territories.

157 tor leads to expansion of the eye field into diencephalic territory and loss of diencephalic structur

158 Diencephalic TH-ir neurons in the periventricular poster

159 c neurons in each of the major forebrain and diencephalic TH-positive cell groups expressed zDJ-1.

160 cephalon is, in fact, expression in adjacent diencephalic tissue, which expresses many of the same ge

161 he other was the absence of the dorsoventral diencephalic tract in Alligator which lacks a pineal gla

162 The constructed detailed diencephalic transcription factor gene expression map fu

163 This phenotype was recapitulated by diencephalic transections that removed the dopaminergic

164 Twelve patients (18%), predominantly with diencephalic tumor location, died of a specific medical

165 ntorial tumors (P = .008), optic pathway and diencephalic tumors (P = .012), and subtotal resection o

166 Patients with diencephalic tumors had inferior FFS and OS compared wit

167 are particularly required for patients with diencephalic tumors.

168 e hypothalamic cells derive from the rostral diencephalic ventral midline, lie above the prechordal m

169 A neurons precede RGC axons into the lateral diencephalic wall and like RGC axons also express GAP-43

170 ignaling required for entry into the lateral diencephalic wall to form the optic tracts.

171 nteraction with guidance cues in the lateral diencephalic wall, suggesting possible involvement of PK

172 sed diencephalic RA signaling, and increased diencephalic WNT and SHH signaling.