ライフサイエンスコーパス: dienoic

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1 iHPODE) and 10,13-dihydroperoxyoctadeca-8,11-dienoic acid (10,13-diHPODE), were postulated as key int

2 ron reduced product, 10-hydroxyoctadeca-8,12-dienoic acid (10-OH-18:2), as well as the one-electron r

3 vestigated using 10-hydroperoxyoctadeca-8,12-dienoic acid (10-OOH-18:2), a diagnostic probe of hydrop

4 tron reduction products, 10-oxooctadeca-8,12 dienoic acid (10-oxo-18:2) and 10-oxodec-8-enoic acid (1

5 tatively identified as 12-epoxyoctadeca-9,15-dienoic acid (12-epoxy-18:2Delta(9,15)) in cultures supp

6 ts in equal amounts: 13-hydroxyoctadeca-8,12-dienoic acid (13-OH-18:2) and the keto fatty acid 13-oxo

7 of Mn-PGHS with 13-hydroperoxyoctadeca-8,12-dienoic acid (13-OOH-18:2) generated two products in equ

8 and the keto fatty acid 13-oxooctadeca-8,12-dienoic acid (13-oxo-18:2).

9 using 15-HETE or 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid (20-HEDE), attenuated autoregulation of CBF

10 operoxides, 9,12-dihydroperoxyoctadeca-10,13-dienoic acid (9,12-diHPODE) and 10,13-dihydroperoxyoctad

11 hydrolyzes 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to 2-hydroxypenta-2,4-dienoic acid

12 2,3-DHB) to 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA), a BphD substrate, which was subseq

13 drolysis of 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA), in which the substrate is subject

14 metabolite 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA).

15 4-dienoic acid (HOPDA) to 2-hydroxypenta-2,4-dienoic acid (HPD) and benzoate.

16 15S)-hydroxy-9, 11-epoxymethanoprosta-5Z,13E-dienoic acid (U46619), also causes platelet aggregation

17 20-HETE agonist, 20-hydroxyeicosa-6(Z) 15(Z)-dienoic acid (WIT003) induced mitogenesis in HUVECs and

18 st catalytic desymmetrization of a prochiral dienoic acid by enantioselective bromolactonization.

19 xy-3-methoxyphenyl)acryloyl]-5 -oxohepta-4,6-dienoic acid ethyl ester], 23 [7-(4-hydroxy-3-methoxyphe

20 ubstrate analog 13(S)-hydroxyoctadeca-9Z,11E-dienoic acid have been determined.

21 ar, compound 13e featuring a phenylpenta-2,4-dienoic acid substituent was shown to be antiproliferati

22 mon 12,15-epoxy-13,14-dimethylnonadeca-12,14-dienoic acid with even-numbered alkyl moiety.

23 ) and densipolic (12-hydroxyoctadec-cis-9,15-dienoic acid) acids.

24 omerization of sorbic acid ((2E,4E)-hexa-2,4-dienoic acid) and singlet oxygen formation to quantify t

25 hoxy-2,6,8-trimethyl-10-phenyldeca-4(E),6(E)-dienoic acid) present in all MCs/Nod.

26 in a total synthesis of 13-oxotridec-9E,11E-dienoic acid, confirming the identity of this product th

27 oxy-3-methoxyphenyl)acryloyl]5- oxohepta-4,6-dienoic acid], and 39 [bis(3,4-dimethoxyphenyl)-1,3-prop

28 Dienoic eicosanoids derived from phospholipid arachidoni

29 Furthermore, the levels of cytokines and dienoic eicosanoids produced in response to an intraperi

30 , decrease the production of proinflammatory dienoic eicosanoids with a concomitant increase in the s

31 o the conjugated dibromodiene 5b [5'(E)] and dienoic ester 7b [5'(E),7'(E)].

32 roM and cytostatic at > or =11 microM, while dienoic esters 16a,b showed activity against both varice

33 3-iodoacrylate gave stereodefined access to dienoic esters 7 (E,E) and 16 (E,Z).

34 In addition to (2Z,4E)-dienoic esters, some (2Z,4E,6E)- and (2Z,4E,6Z)-trienoic

35 gest that oral exposure to the monoenoic and dienoic fatty acid component of dietary fat selectively

36 ARgamma activation observed for nitrated 1,4-dienoic fatty acids (E-9-NO2-18:2, E-10-NO2-18:2, E-12-N

37 sed a corresponding increase in the level of dienoic fatty acids.

38 several positional and geometric conjugated dienoic isomers of linoleic acid, which have been shown

39 n phospholipids due to reduced conversion of dienoic to trienoic fatty acids in the endoplasmic retic

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