ライフサイエンスコーパス: diethylamino

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1 Treatment with NSC23766 (N(6)-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidiny

2 e of stereoselectivity was developed using 3-diethylamino-1-propanol (deapH) in lieu of BnOH and NEt(

3 eceptor antagonist JNJ-31020028 (N-(4-(4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl)-3-fluo

4 m in some food samples, which used 3',6'-bis(diethylamino)-2-{[(1E)-(4-ethoxyphenyl) methylene] amino

5 The deprotonation of pentacarbonyl[(3-diethylamino-2,4-dimethyl)cyclobut-2-ene-1-ylidene]chrom

6 lculations were performed on pentacarbonyl[3-diethylamino-2,5-dimethyl)cyclopent-2-ene-1-ylidene]chro

7 the parent compound 4-guanidinophenyl (E)-4-diethylamino-2-hydroxy-alpha-methylcinnamate hydrochlori

8 ylation reactions to generate MEGX and omega-diethylamino-2-hydroxymethyl-6-methylacetanilide.

9 yeast actin by a sulfhydryl reagent CPM [7-(diethylamino)-3-(4'-maleimidophenyl)-4-methylcoumain] wa

10 yl)-2-(dimethylamino)naphthalene (BADAN), 7-(diethylamino)-3-(4'-maleimidylphenyl)-4-methylcoumarin (

11 The modification of Cys(154) with 7-(diethylamino)-3-(4'-maleimidylphenyl)-4-methylcoumarin (

12 by site-directed mutagenesis, labeled with 7-diethylamino-3-((((2-iodoacetamido)ethyl)amino)carbonyl)

13 on maxima of a solvatochromic fluorophore (7-diethylamino-3-((((2-maleimidyl)ethyl)amino)carbonyl) co

14 of the enzyme was developed by conjugating 7-diethylamino-3-((((2-maleimidyl)ethyl)amino)carbonyl)cou

15 te maleimide, SDSM) and membrane-permeable 7-diethylamino-3-(4'-maleimidyl)-4-methylcoumarin (CPM).

16 nal sarcoplasmic reticulum is labeled with 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin (C

17 ar quantities of the fluorogenic maleimide 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin (C

18 de, 3-(N-maleimidopropionyl)-biocytin, and 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin al

19 th the fluorescent monofunctional reagents 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin an

20 and ryanodine receptor type 1 (RyR1) with 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin, a

21 ry-based peptide sequencing, we identified 7-diethylamino-3-(4'-maleimidylphenyl)-4-methylcoumarin-th

22 NMT1 and NMT2 based on detection of CoA by 7-diethylamino-3-(4-maleimido-phenyl)-4-methylcoumarin.

23 ET) between a protein fusion LuxP-EGFP and 7-diethylamino-3-[N-(2-maleimidoethyl)carbamoyl]coumarin (

24 For the first-time 7-Diethylamino-3-thenoylcoumarin (DETC) is used as the pho

25 cer dye, rhodamine B ([9-(2-carboxyphenyl)-6-diethylamino-3-xanthenylidene]-diethylammonium chloride)

26 -ylidene]chromi um (1d) and pentacarbonyl[(3-diethylamino-4-methyl-2-phenyl)cyclobut-2-ene-1-ylidene]

27 Appp-S-(7-diethylamino-4-methyl-3-(4-succinimidylphenyl)) coumarin

28 ey contained 156 mmol/kg Cu-I, 10 mmol/kg 9-(diethylamino)-5-[4-(15-butyl-1,13-dioxo-2,14-dioxanodecy

29 The lipid soluble fluorophore Nile Red (9-diethylamino-5-benzo[alpha]phenoxazinone) is used to flu

30 can be replaced by a triazole system, the 5-(diethylamino)acetamido substituent found in 8a is requir

31 spontaneously NO-releasing salts 1a (R(2)N = diethylamino) and 1b (R(2)N = pyrrolidino) to prodrugs 2

32 In particular, the MediaChrom bearing a diethylamino as an electron-donating group and a trifluo

33 Here, we describe diethylamino-azo-diethylamino (DAD), a third-generation

34 methylbenzophenone, 2-adamantanone, 4,4'-bis(diethylamino)benzophenone, and 1,2-diphenylcyclopropen-3

35 The 3-(diethylamino)benzyl (DEABn) group has been studied for r

36 The two most potent compounds 10-[4'-(N-diethylamino)butyl]-2-chlorophenoxazine (10B) and 10-[4'

37 For example, the introduction of a [4-(diethylamino)butyl]amino side chain into the 2-position

38 merization process which afforded 7,7'-bis(((diethylamino)carbonyl)oxy)-6,6'-diiodo-8,8'-biquinolyl (

39 Sphingolipid phosphate analogues bearing 7-(diethylamino)coumarin (DECM) and 4-bromo-5-hydroxy-2-nit

40 of glycine was covalently coupled to the 7-(diethylamino)coumarin (DECM) caging group.

41 ith the fluorescent probe 3-(bromoacetyl)-7-(diethylamino)coumarin (PgammaBC, Pgamma-24-45BC) have be

42 gh molecular weight carbonylated LPP with 7-(diethylamino)coumarin-3-carbohydrazide (CHH) and analyze

43 at Cys197 with N-[2-(1-maleimidyl)ethyl]-7-(diethylamino)coumarin-3-carboxamide (MDCC).

44 We present the synthesis of [7-(diethylamino)coumarin-4-yl]methyl (DEACM)-caged phosphor

45 protein MDCC-PBP, N-(2[1-maleimidyl]ethyl)-7-diethylamino-coumarin-3-carboxamide phosphate binding pr

46 ethylamino)-cyclopropenium chloride and tris(diethylamino)-cyclopropenium iodide reveal the presence

47 Here, we describe diethylamino-azo-diethylamino (DAD), a third-generation photoswitch that

48 diazen-1-ium-1,2-diolate (13 and 18), 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate (14 and 19), or ni

49 thione (GSNO) or diethylammonium (Z)-1-1(N,N-diethylamino)diazen-1-ium-1,2-diolate (DEA NONOate) to h

50 ctile response to the NO donor sodium 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate was not altered.

51 Using the NO generator 1-(N,N-diethylamino)diazen-1-ium-1,2-diolate, we were able to g

52 photochemistry of the sodium salt of 1-(N,N-diethylamino)-diazen-1-ium-1,2-diolate (3) has been inve

53 on with cGMP-elevating agents such as 2-(N,N-diethylamino)-diazenolate-2-oxide diethylammonium salt (

54 rmed with NO or the NO donors NOC9 or 2-(N,N-diethylamino)-diazenolate-2-oxide.sodium salt.

55 erivatization of protonated analytes by (N,N-diethylamino)dimethylborane in a Fourier transform ion c

56 solation of a disulfide intermediate (Z)-2-[(diethylamino)disulfan-yl]-2-[(1H-pyrazol-5-yl)imino]acet

57 sence of acid, heating a solution of (Z)-2-[(diethylamino)disulfanyl]-2-[(1,3-dimethyl-1H-pyrazol-5-y

58 2-(Diethylamino)ethanethiol (DEAET) and 2-(dimethylamino)et

59 of 2-(dimethylamino)ethanethiol (DMAET), 2-(diethylamino)ethanethiol (DEAET), and 2-mercaptoethanol

60 e deprotection of aromatic methyl ethers, 2-(diethylamino)ethanethiol, is reported.

61 that progesterone, imipramine and 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one (U18666A) strong

62 ic delivery of (1R-1-benzo thiophen-5-yl-2[2-diethylamino)-ethoxy] ethanol hydrochloride (T-588) prev

63 ties), our initial lead, T3.5 (3-chloro-6-(2-diethylamino-ethoxy)-10-(2-diethylamino-ethyl)-acridone)

64 uscarinic receptor antagonist aprophen [(N,N-diethylamino)ethyl 2,2-diphenylpropionate], were synthes

65 moresponsive synthetic hydrogels based on 2-(diethylamino)ethyl acrylate, which support long-term hum

66 well-defined styrene-functionalized poly(2-(diethylamino)ethyl methacrylate) macromonomer as a react

67 he deprotecting reagent and the byproduct 2-(diethylamino)ethyl methyl sulfide into the aqueous phase

68 lthio)phenyl)(naphthalen-1-yl)methanone O-2-(diethylamino)ethyl oxime (MND) exhibited the best safety

69 ich protect mice against 4.2 LD(50) of S-(2-(diethylamino)ethyl) O-isobutyl methanephosphonothioate w

70 Melanin targeted N-(2-(diethylamino)ethyl)-18F-5-fluoropicolinamide was used as

71 le by Bu and colleagues (1) introduces N-[2-(diethylamino)ethyl]-(18)F-5-fluoropicolinamide ((18)F-P3

72 In this study, N-[2-(diethylamino)ethyl]-4-(18)F-fluorobenzamide ((18)F-FBZA)

73 hylamino)ethyl]benzenesulfonamides and N-[2-(diethylamino)ethyl]benzenemethanesulfonamides have been

74 and two compound classes consisting of N-[2-(diethylamino)ethyl]benzenesulfonamides and N-[2-(diethyl

75 One such benzamide, N-(2-diethylamino-ethyl)-4-(4-fluoro-benzamido)-5-iodo-2-meth

76 .5 (3-chloro-6-(2-diethylamino-ethoxy)-10-(2-diethylamino-ethyl)-acridone), demonstrates unique syner

77 te portion of aprophen by replacement of the diethylamino group.

78 agents, (12)C4-, (12)C2(13)C2-, and (13)C4-5-diethylamino-naphthalene-1-sulfonyl chloride (DensCl), i

79 can regulate calcium signaling, including 8-(diethylamino)octyl-3,4,5-trimethoxybenzoate and 2-aminoe

80 um chelators 3,4,5-trimethoxybenzoic acid 8-(diethylamino)-octyl ester (TMB-8) and 2-[(2-bis-[carboxy

81 bitor of intracellular Ca2+ mobilization, 8-(diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochlori

82 e), the intracellular Ca(2+) channel (8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate), CaM (N-(6

83 elator, or with the combined presence of [8-(diethylamino)-octyl-3,4,5-trimethoxybenzoate, HCl] (TMB)

84 1 micromol/ 3,4,5-trimethoxybenzoic acid 8-[diethylamino]octyl ester, an intracellular Ca2+ antagoni

85 tion, adding R 2NN(O)NO-GlcNAc (where R 2N = diethylamino or pyrrolidin-l-yl and GlcNAc = N-acetylglu

86 FM4-64 [N-(3-triethylammoniumpropyl)-4-(6-(4-diethylamino)phenyl)-hexatrienyl)pyridinium dibromide].

87 pound, N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrie nyl )pyridinium dibromide (

88 tracer N-(3-triethylammoniumpropyl)-4-(6-(4-(diethylamino)phenyl)hexatrienyl)pyridinium dibromide.

89 FM4-64 [N-(3-triethylammoniumpropyl)-4-(6-(4-diethylamino)phenyl)hexatrienyl)pyridinium dibromide] dy

90 /2-chloro-(epsilon-amino-Lys(75))-[6-[4-(N,N-diethylamino)phenyl]-1 ,3,5-triazin-4-yl]calmodulin] sho

91 ts using 2-chloro-(amino-Lys(75))-[6-[4-(N,N-diethylamino)phenyl]-1,3,5-triazin-4-y l]calmodulin (TA-

92 The most potent hit compound, N-[4-(diethylamino)phenyl]-5-methyl-3-phenylisoxazole-4-carbox

93 n, 2-chloro-(epsilon-amino-Lys75)-[6-(4-N, N-diethylamino-phenyl)-1,3,5-triazin-4-yl]-calmodulin (TA-

94 sized by the reaction of Pb-oleate with tris(diethylamino)phosphine selenide are highly sensitive to

95 cid in the reaction can also react with tris(diethylamino)phosphine to create bis(diethylamido)phosph

96 nd (1)H NMR show that water reacts with tris(diethylamino)phosphine to create bis(diethylamido)phosph

97 two expected contributing structures, and 2-(diethylamino)propane and 1,8-diazabicyclo[6.3.1]dodecane

98 observed following reaction with 1-ethyl-3-[(diethylamino)propyl]carbodiimide.

99 d 3 and the monosubstituted compounds 2-(N,N-diethylamino)pyrene (1) and 2-cyanopyrene (2) have been

100 our approach, we synthesized 2-cyano-7-(N,N-diethylamino)pyrene (3), a pyrene analogue of the widely

101 ffinity labeling (PAL) agent, 5-azido-2-(N,N-diethylamino)pyridine, was studied in aprotic and protic

102 derivatives or 1,3,5-benzenetriamine and 4-(diethylamino)salicylaldehyde, while a second series resu

103 es used the fluorescent DAT substrate, 4-[4-(diethylamino)-styryl]-N-methylpyridinium iodide (ASP(+))

104 double labeled with a fluorescent dye, 4-(4-diethylamino-styryl)-N-methylpyridinium iodide, for NTs

105 The diethylamino-substituted derivative has a proton associa

106 esis of a new tricyclic cytidine analogue, 8-diethylamino-tC (8-DEA-tC), that responds to DNA duplex

107 peridyl) and (1-NEt2-2-BH2-C6H4)2 (3; NEt2 = diethylamino), were synthesized, and their structural fe

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