ライフサイエンスコーパス: differentiated

1 lioid and sarcomatous components), or poorly differentiated.

2 that were morphologically classified as well differentiated.

3 r expressed epithelial markers and were more differentiated.

4 SAM binds to the unique iron atom of a site-differentiated [4Fe-4S] cluster and is reductively cleav

5 The CSF RT-QuIC differentiated 94% of cases of sporadic Creutzfeldt-Jako

6 joint assembly, 1 mm IVPA-US catheter size, differentiated A-line strategy, and real-time image proc

7 t preclinical prostate tumor models could be differentiated according to hemosiderin iron accumulatio

8 ogate checkpoints that prevent conversion of differentiated acinar cells to proliferative ductal prog

9 We found that DNA methylation at birth differentiated ADHD trajectories across multiple genomic

10 Daily exposure of differentiated adipocytes to blue light resulted in decr

11 fects of mono-ethylhexyl phthalate (MEHP) in differentiated adipocytes.

12 sion in both white adipose tissue and 3T3-L1 differentiated adipocytes; in the latter, Pep19 activate

13 ly, relatively undifferentiated and strongly differentiated adult castes.

14 gic levels of OSM impair barrier function in differentiated airway epithelium.

15 nomic regions harboring variants with highly differentiated allele frequencies among the ancestral po

16 ical isolates within each outbreak, and also differentiated among the three outbreak strains and epid

17 Differentiated analysis of MR imaging subgroups again re

18 tivated nonexhausted phenotype, but was less differentiated and associated with coexpression of multi

19 However, the molecular identity of the differentiated and dedifferentiated states in vivo has b

20 that certain compositions cannot be clearly differentiated and lie in a "confused" region (0.3-0.7 c

21 Differentiated and transplanted RGC-like cells derived f

22 the state of pluripotency and when cells are differentiated, and that this effect allows a more preci

23 ferentiated], intermediate-grade [moderately differentiated], and high-grade [poorly differentiated],

24 erences in patient pathways to care call for differentiated approaches to patient-centered care.

25 atient care seeking and suggested a need for differentiated approaches, by province, to respond to va

26 mblages on formerly connected islands are as differentiated as assemblages on islands that have never

27 ling SS18-SSX-driven oncogenesis in cells as differentiated as preosteoblasts.

28 n A state, and two solution species that are differentiated based on a cis- or trans-configured Glu(1

29 eaking the network metrics into subsets that differentiated between contacts with yearlings, ewes wit

30 on, miR-125a-5p, miR-125b-5p, and miR-143-3p differentiated between healthy control subjects and pati

31 , item discrimination (how well the question differentiated between high and low abilities), and aver

32 MeMSChem profiles also partially differentiated between individuals, suggesting that ever

33 tion of three classes of KMO inhibitors with differentiated binding modes and kinetics.

34 t in conventional methods, and show that all differentiated bodies have isotopically heavier magnesiu

35 nd induced an epithelial phenotype in poorly differentiated breast cancer cells.

36 rent antibody isotypes can be quantitatively differentiated by adopting secondary antibodies.

37 the economic burden of dengue in any region, differentiated by four very different domains of cost it

38 ytes cultured in hypoxia and normoxia can be differentiated by their lipid profiles.

39 tive samples of men in each country who were differentiated by their underlying reasons for their pro

40 destruction of the epithelial barrier in the differentiated Caco-2 cells in vitro.

41 s inhibited (14)C-D-glucose transport across differentiated Caco-2/TC7 cell monolayers, but they inhi

42 advanced (unresectable or metastatic), well differentiated carcinoid tumours of the lung or thymus,

43 striking nuclear atypia and invasive, poorly differentiated carcinoma.

44 t does not alter the numbers of activated or differentiated cardiac fibroblasts in vivo.

45 stem cells, mesoderm, cardiac mesoderm, and differentiated cardiomyocytes.

46 ll-enriched (CD34(+) and CD34(+)CD38(-)) and differentiated (CD34(-)) cells derived from individuals

47 d were associated with higher counts of late differentiated CD8+ T cells.

48 eep was unrelated to epigenetic age and late differentiated cell counts, but was related to a decline

49 similar levels of efficacy and contained all differentiated cell lineages.

50 ome, RNAs isolated from undifferentiated and differentiated cell populations of normal, spontaneously

51 Osteocytes are the terminally differentiated cell type of the osteoblastic lineage and

52 t is adapted to the specialized functions of differentiated cell types and opens new research avenues

53 However, TKIs primarily target differentiated cells and do not eliminate leukemic stem

54 orithms to separate the progenitors from the differentiated cells and reconstruct the lineage hierarc

55 the accumulation of polyubiquitin chains in differentiated cells and stabilized by the proteasome in

56 crotubule dynamics and functions in vivo, in differentiated cells and tissues, remains under-explored

57 mans indicates that TSCM cells are minimally differentiated cells at the apex of the hierarchical sys

58 We investigated whether differentiated cells can give rise to SPEM using a nonge

59 We found that differentiated cells derived from isogenic iPSCs and nt-

60 alternatives for generating patient-specific differentiated cells for disease modeling and preclinica

61 molecular and functional characteristics of differentiated cells from human PSCs are primarily attri

62 g action of mtROS and inflammasomes in fully differentiated cells in the retina, the removal of the d

63 The reprogramming of differentiated cells into induced pluripotent stem cells

64 the generation of essential sphingolipids in differentiated cells is not well understood.

65 Characterization of differentiated cells is performed via flow cytometry and

66 Furthermore, endocytic capacity in fully differentiated cells is rapidly modulated by changes in

67 for nucleotide analogues to inhibit HIV-1 in differentiated cells low in dNTPs.

68 liferation in response to IL-7, whereas more differentiated cells proliferated poorly.

69 al endothelial cells (HCEnCs) are terminally differentiated cells that have limited regenerative pote

70 Such an approach can produce differentiated cells to study physiology or pathophysiol

71 hes, which have revealed that, although some differentiated cells utilize conserved strategies to rem

72 tform can thus rapidly generate high quality differentiated cells, both neurons and potentially other

73 In differentiated cells, chromosomes are packed inside the

74 ble to self-renew, proliferate, and generate differentiated cells, consistent with a progenitor/stem

75 To investigate the mechanisms that maintain differentiated cells, here we inducibly delete the histo

76 ch is a non-limiting enzyme of glycolysis in differentiated cells, was tightly regulated in stem cell

77 ors as the initial step in the production of differentiated cells.

78 endolymphatic sacs demonstrates two types of differentiated cells.

79 ctivities and distinguishes pluripotent from differentiated cells.

80 toplasm in pluripotent P19 cells, but not in differentiated cells.

81 emotherapy-induced cell death less than more differentiated cells.

82 he distribution of transposable elements and differentiated chromosome blocks into two groups consist

83 ion, albeit in GSK-3beta independent manner, differentiated colon cancer in claudin-3-/- mice versus

84 The most differentiated compound, D3-2, displayed a 180-fold high

85 h increasing mesenchymal phenotype in poorly differentiated CRC cell lines as a consequence of repres

86 formed to identify protein combinations that differentiated CRC or advanced adenoma from control samp

87 lar transit amplifying (TA) and a definitive differentiated (D) CD31hiVEGFR2hi/extracellular populati

88 Benefit from chemotherapy for well-differentiated/de-differentiated (WD/DD) liposarcomas ha

89 ersal donor cells for applications where the differentiated derivatives lack HLA class II expression.

90 sarcoma represents focal progression of well-differentiated disease into a more aggressive, metastasi

91 re, caudate functional connectivity patterns differentiated distinct corticostriatal pathways associa

92 patients with data available for analysis; g differentiated docetaxel (a US Food and Drug Administrat

93 ical in neurons, which comprise vast, highly differentiated domains such as the axon and dendrites.

94 other effector cells develop into terminally differentiated effector (TE) cells with limited survival

95 activated CD4(+) T cell produces terminally differentiated effector cells and renews itself for cont

96 l CD4(+) and CD8(+) T cells exhibit a highly differentiated effector memory phenotype in comparison w

97 cell, effector memory T cell, and terminally differentiated effector T cell populations to the CD3 an

98 naive, effector memory (EM), and terminally differentiated EM (TEMRA) cells.

99 Many terminally differentiated endocrine cell types, however, remain enr

100 y, D cells highly expressed genes related to differentiated endothelium including Ets1&2, Gata2, Cd31

101 (K10) are the primary keratins expressed in differentiated epidermis.

102 strate fundamentally new roles of TMEM16A in differentiated epithelial cells: TMEM16A provides a mech

103 aled a higher mean vessel density and poorly differentiated extracellular matrix (ECM) in MDA-MB-231

104 Clonal expansions have differentiated from a naive to effector phenotype associ

105 tly reprogrammed from human somatic cells or differentiated from an iPSC intermediate, the overview p

106 miR-29b promotes atrophy of myotubes differentiated from C2C12 or primary myoblasts, and conv

107 Sex chromosomes differentiated from different ancestral autosomes in var

108 The populations were significantly differentiated from each other (overall FST=0.23), and t

109 rboxylic acids and sulfonamides could not be differentiated from each other.

110 air shaft progenitors in the matrix that are differentiated from follicular epithelial cells expressi

111 s the nuclear lamina architecture in neurons differentiated from FXTAS iPS cells.

112 estigated its function in cerebral organoids differentiated from gene-edited hESCs lacking RB.

113 ts provide a description of V2a interneurons differentiated from hPSCs that may be used to model cent

114 fat precursors and in human brown fat cells differentiated from human neck brown preadipocytes.

115 This cell population can be successfully differentiated from human pluripotent stem cells (hPSCs)

116 t human microglial-like cells (iMGLs) can be differentiated from iPSCs to study their function in neu

117 ients with antibody-mediated conditions were differentiated from multiple sclerosis with high accurac

118 zymes that displace mismatched bases, and is differentiated from other DNA-targeted chemotherapeutics

119 migration utilizing airway mucosal barriers differentiated from primary human airway basal cells and

120 iated muscle is energy-dynamic but not fully differentiated from smooth muscle.

121 Currently, hepatocyte-like cells differentiated from stem cells still fall short of recap

122 ed reticulon-1 mRNA expressed in macrophages differentiated from the BM of UV-chimeric mice.

123 Even the Virus-Low group was differentiated from the No-Virus group by 100 genes, som

124 This population became less differentiated from the other populations suggesting eff

125 but distinct from Seneca's main writings are differentiated from the rest of the corpus by subtle but

126 RPE cells differentiated from these hiPSCs contained morphological

127 ing from (2)H-labeled tracers are completely differentiated from those arising from (13)C-labeled tra

128 ecies present at a particular site cannot be differentiated from those species present at the other g

129 the highest clustering level, the algorithm differentiated functionally adaptive and maladaptive gro

130 Twelve patients with well-differentiated gastroenteropancreatic (GEP) NETs took pa

131 ells revealed the collapse of the terminally differentiated gene program, indicated by a loss of beta

132 Importantly as metabolites differentiated genotype, genotype-differentiating metabo

133 d extent of conidial swelling, production of differentiated germination-structures and septate germli

134 Conidia swelled, formed differentiated germination-structures and then produced

135 h markers tended to be in well-to-moderately differentiated glands with nuclear polarization, but exc

136 hormone gene, Lhb We demonstrate that poorly differentiated gonadotropes express a TET1 isoform lacki

137 ectable or metastatic), non-functional, well-differentiated (grade 1 or 2) NETs of lung or gastrointe

138 Pathology review indicated a poorly differentiated, grade 3 invasive ductal carcinoma and du

139 es and only to few atrial cells (<5%) of the differentiated heart.

140 nfection activated cellular PLK1 in PHHs and differentiated HepaRG cells.

141 ctive tropism for the apical surface of well-differentiated human airway epithelia (HAE).

142 ed hepatocyte-like cells to their terminally differentiated human counterparts using defined phenotyp

143 ol for deriving colonic organoids (COs) from differentiated human embryonic stem cells (hESCs) or ind

144 RNA sequencing following CLOCK knockdown in differentiated human neurons in vitro.

145 We differentiated human pluripotent stem cells (hPSCs) into

146 and CD200R identified peanut-specific highly differentiated IL-4(+) IL-5(+) Th2 cells.

147 Finally, in brown adipocytes differentiated in culture, MLL4 identifies primed SEs of

148 nses could be recapitulated in wt mast cells differentiated in the absence of succinate.

149 mune responses of moDCs with those that were differentiated in the presence of CXCL4.

150 Tolerogenic dendritic cells were differentiated in the presence of IL-10 from PBMCs of pa

151 uced in vitro in esophageal epithelial cells differentiated in the presence of IL-13.

152 the extreme winter, 14 genomic regions were differentiated in the surviving southern population; fou

153 species consists of provenances that are not differentiated in their thermal responses, thus rejectin

154 d macrophage differentiation, sJIA monocytes differentiated in vitro toward macrophages, away from th

155 e test allows the major prion subtypes to be differentiated in vivo.

156 e curves with the allergens in BAT allowed a differentiated individual dissection of relevant sensiti

157 The differentiated induction of detoxification enzymes by 2,

158 ll-accepted treatment for patients with well-differentiated inoperable or metastatic NETs and disease

159 ic grade (G1, G2, or G3, for low-grade [well differentiated], intermediate-grade [moderately differen

160 The GAS M protein, by which strains are differentiated into >220 different emm types, is immunog

161 ibe an in vitro method by which hPSCs can be differentiated into 3D retinas with at least some import

162 We show that ADSCs differentiated into adipocytes and accumulated lipids in

163 transplanted into injured adult mouse lungs differentiated into all major airway and alveolar lineag

164 ne-deficient mice, SF3B1 mutated MDS-RS HSCs differentiated into characteristic ring sideroblasts, th

165 duced pluripotent stem cells (hiPSCs) can be differentiated into CMs (hiPSC-CMs) that model cardiac c

166 demonstrate that alphaSMA-tdTomato(+) cells differentiated into Col2.3-GFP(+) cells composed of both

167 When HD NPCs were further differentiated into DARPP32-positive neurons, these HD n

168 how that these iPSC lines can be efficiently differentiated into hematopoietic stem cell precursors,

169 mmitted epithelial progenitors of the ureter differentiated into intermediate cells at E14.5.

170 e or non-classical subsets, and subsequently differentiated into M1 pro- or M2 anti-inflammatory macr

171 hiPSCs can be differentiated into mature and functional dopaminergic (

172 , but this capacity was lost after the cells differentiated into mature fibrochondrocytes.

173 derwent extensive somatic hypermutation, and differentiated into memory B cells.

174 Huh7 cells and to C2C12 mouse myoblasts that differentiated into myotubes.

175 HIOs in vitro migrated into the mesenchyme, differentiated into neurons and glial cells and showed n

176 Primary cultures of porcine RPE cells were differentiated into polarized RPE monolayers on permeabl

177 anded to generate large numbers of cells and differentiated into presumably all the cell types of the

178 lularized renal scaffolds with basal medium, differentiated into proximal and distal tubules as well

179 Transplanted Sox10(+) stem cells differentiated into smooth muscle cells to stabilize fun

180 CAF-like phenotype, suggesting that they had differentiated into the subpopulations of cells that sup

181 The habenula is an epithalamic structure differentiated into two nuclear complexes, medial (MHb)

182 that MT dynamics are strongly suppressed in differentiated keratinocytes in two distinct steps due t

183 physiologic function of in vitro and in vivo differentiated kidney tissue, strategies for engraftment

184 The mammary gland epithelium consists of differentiated luminal epithelial and basal myoepithelia

185 t express NKX2-1 but are initially devoid of differentiated lung lineage markers.

186 achieves efficient replication in terminally differentiated macrophages despite the restriction facto

187 icular, the human progenitor cell population differentiated, matured, and integrated into the rodent

188 Adoptive transfer of in vitro differentiated MCs restored thrombosis.

189 givalis mutant strains to show that pathogen-differentiated mDCs from primary human-monocytes display

190 r than 35 cells CD8CD28 end-stage terminally differentiated memory T cells/muL rejected, median pretr

191 Moreover, differentiated monocytes presented with profound transcr

192 of glutamate was also increased in TGF-beta1-differentiated myofibroblasts compared with controls, wh

193 late, and citrate were observed in TGF-beta1-differentiated myofibroblasts.

194 that Hmox1(-/-) SCs are shifted toward more differentiated myogenic population.

195 However, in poorly differentiated NETs, (18)F-FDG PET/CT plays a significan

196 In 11 (39.2%) of 28 patients with poorly differentiated NETs, the management decision was based o

197 velopment, and transcellular transmission in differentiated neural progenitor cells (dNPCs) and neuro

198 of the tumorigenesis and treatment of poorly differentiated neuroendocrine tumors.

199 However, terminally differentiated, neuronal SH-SY5Y cells release significa

200 educed the number and function of terminally differentiated NKT and gammadelta T cells in the thymus,

201 Here we have engineered and developmentally differentiated NKX2-1GFP reporter pluripotent stem cells

202 GSCs more potently than it did the growth of differentiated non-stem glioma cells (NSGCs).

203 efficient genome amplification in both well-differentiated (nondividing) HAE and dividing HEK293 cel

204 ome, and HBoV1 replicates only in terminally differentiated, nondividing cells.

205 l of cancer drugs compared with GC of a more differentiated origin.

206 The numbers of tumor driver mutations are differentiated (p < 0.05) over the racial groups in five

207 ls are anti-proliferative in benign and well-differentiated pancreatic cells, TGFbeta appears to prom

208 re podocytes undergo a deregulation of their differentiated phenotype and proliferate.

209 ority of NK cells in human lungs, had a more differentiated phenotype, and more frequently expressed

210 myocytes many days before cells manifest the differentiated phenotype.

211 ansition from progenitor cells to terminally differentiated photoreceptors.

212 This gives us a uniquely differentiated picture of the neural substrate for the f

213 as long been recognized that Earth and other differentiated planetary bodies are chemically fractiona

214 analysis confirmed CHX10(+) cells within the differentiated population, which consisted primarily of

215 cycle, RNA-Seq was carried out on triplicate differentiated populations of NIKS (uninfected) and NIKS

216 PEM derives from proliferating stem cells or differentiated, post-mitotic zymogenic chief cells in th

217 SeptiCyte Lab strongly differentiated postcardiopulmonary bypass and clinically

218 a large population of individual granules in differentiated primary bronchial epithelial cells using

219 s an autonomous parvovirus that infects well-differentiated primary human airway epithelia (HAE) in v

220 he osteotropic PC-3M-Pro4Luc2 PCa cells with differentiated primary human osteoblasts induced CRIPTO

221 Pressed honey, can be marked as a differentiated product with a higher mineral content and

222 Vdelta2 T cells presented a terminally differentiated profile, expressed granzyme B and maintai

223 therapeutic potential of stem cells or their differentiated progenies will depend on their capacity t

224 ukemia stem cells (LSCs) compared with their differentiated progeny.

225 iphosphate (UTP)-stimulated ion transport in differentiated, pseudostratified epithelia derived from

226 A second experiment revealed that adults differentiated recombined and standard combinations when

227 tely differentiated], and high-grade [poorly differentiated], respectively), chromogranin A, and prol

228 ndicated poised state of NtcA enables a more differentiated response to nitrogen limitation and can b

229 ted optimal cut-off absorbance-value of 2.1, differentiated S. pneumoniae from all but one other miti

230 of West African children with SCD, cluster 1 differentiated SCD severity using a published scoring in

231 train A-85/14, and a PCR was formulated that differentiated serovar 16 isolates from all 15 known ser

232 These differentiated Sertoli cells remained mitotically active

233 We demonstrate that terminally differentiated SH-SY5Y cells have neuronal morphology an

234 We found that exposure of neuronally differentiated SH-SY5Y cells to AM, OT and PT triggered

235 s of single-stained cells, and such patterns differentiated short from long time-to-progression with

236 ial fusion protein optic atrophy 1 (OPA1) in differentiated skeletal muscle by reducing OPA1 gene exp

237 this striated muscle-specific enzyme in more differentiated skeletal muscle remain unknown.

238 n of resident vascular progenitor cells from differentiated SMCs is a normal physiological process th

239 nduction of the transcription factor Klf4 in differentiated SMCs is essential for SMC reprogramming i

240 high, individuals developed stable and more differentiated social ties compared to when perceived ri

241 These biotypes cannot be differentiated solely on the basis of clinical features,

242 m CE polarity are required for commitment to differentiated somatic cell fates.

243 ly, this work provides in vivo evidence that differentiated somatic cells can be reprogrammed into ca

244 stem cells are fundamentally different from differentiated somatic cells in their innate immunity, w

245 tion owing to recent language formation from differentiated sources [27-31].

246 histotypes comprised a mixed papilloma/well-differentiated squamous cell carcinoma (wdSCC), exhibiti

247 WGS analysis differentiated ST382 from a clonal complex 1 outbreak st

248 ng constitutively to maintain VSMCs in their differentiated state and, thereby, inhibit aberrant sign

249 Thus, LDB1 maintains the terminally differentiated state of beta cells and is a component of

250 switched perivascular cells promoted a less differentiated state, characterized by enhanced ECM prod

251 rs is delayed, and they never attain a fully differentiated state.

252 henotype that developed toward a more mature differentiated status.

253 alling regions exist at the apical border of differentiated surface cells.

254 iomarkers from different data platforms that differentiated survivors and fatalities early after infe

255 t by passaging an H9N2 strain three times in differentiated swine airway epithelial cells.

256 e, naive T cell (CD8+CD45RA+CCR7+), and late differentiated T cells (CD8+CD28-CD45RA-).

257 elopment and indicates that intrahepatically differentiated T cells contribute to the CD4(+) T-cell p

258 Many studies have highlighted the role of differentiated T lymphocytes in psoriasis progression.

259 -17A production from murine T helper type 17-differentiated T lymphocytes.

260 d 352 patients with RAI-avid metastatic well-differentiated TC treated with (131)I by an empiric fixe

261 d synthesis in MPEC compared with terminally differentiated Teff.

262 ion studies employing a series of sterically differentiated tertiary amines suggest that the steric n

263 Additional analysis of in vitro-differentiated Th0, Th1, and Th2 cultures identified CD2

264 onfirmed that the production of IFN-gamma by differentiated Th1 cells is more sensitive to 3-BrPa tha

265 tor commitment, T-bet acts as a repressor in differentiated Th1 cells to prevent abberant autocrine t

266 ly stimulated antigen-specific population of differentiated Th1 cells.

267 have never been connected, and both are more differentiated than local assemblages sampled up to two

268 Contrast material maps clearly differentiated the distributions, with gadolinium solely

269 me warming dominated the climate impacts and differentiated the EVI trend.

270 This may result in highly differentiated therapeutics with greater efficacy and/or

271 , and cortical stroma; p-Creb was present in differentiated thick ascending limb of Henle, collecting

272 Patients with metastatic differentiated thyroid cancer (DTC) may be prepared usin

273 Several susceptibility loci of differentiated thyroid cancer (DTC) were identified by p

274 opulation-based cohort of patients with well-differentiated thyroid cancer (WDTC) treated or not with

275 included cohorts of persons treated for well-differentiated thyroid cancer and persons with no surger

276 lar thyroid cancer is the second most common differentiated thyroid cancer histological type and has

277 SDHD in autophagy-associated pathogenesis of differentiated thyroid cancer.

278 logical features of human RAS-driven, poorly differentiated thyroid cancers.

279 in face recognition, and ultimately leads to differentiated tissue properties between face- and place

280 d a high level of aneuploidy in post-mitotic differentiated tissue.

281 that this isoform is also expressed in other differentiated tissues, and that it is regulated by an a

282 Fibroblasts differentiated to adipocytes and treated with TIP39 also

283 In contrast, genetically corrected ESCs differentiated to CD4 + or CD8 + single-positive T cells

284 show that Lmo2-/- mouse embryonic stem cells differentiated to Flk-1+ haemangioblasts, but less effic

285 These can be expanded and differentiated to form an epithelial layer expressing K1

286 oidal endothelial cells (LSECs) are uniquely differentiated to fulfill important organ-specific funct

287 suggesting that microenvironments are highly differentiated transcription domains.

288 r experiments revealed that intrahepatically differentiated Treg cells relocated to the inflamed aort

289 g in mice the genes encoding both factors in differentiated Tregs, we show that Thpok and LRF are red

290 o therapy if there is negative feedback from differentiated tumor cells that inhibits the rate of tum

291 ement and vascular patterning approaches, we differentiated tumors displaying innate versus acquired

292 the growth of significantly larger and less differentiated tumors when injected into nude mice.

293 Functional human epicardial cells differentiated via this protocol may constitute a potent

294 y switch between two stable states (stem and differentiated) via an unstable (committed) state.

295 of perception, we identified processes that differentiated voice-hearers from non-voice-hearers and

296 s genetic consequences expected to result in differentiated wave-front populations with low genetic v

297 eumatology, we have to approach AD in a more differentiated way (ie, to dissect and stratify the comp

298 from chemotherapy for well-differentiated/de-differentiated (WD/DD) liposarcomas has been reported to

299 tro, yet retain the capacity to become fully differentiated when placed into conditions that mimic th

300 uzumab expressed EMT markers and were poorly differentiated, whereas tumors exposed to the combinatio