ライフサイエンスコーパス: differentiation process

1 e not been thought to play a role in the mDA differentiation process.

2 res additional signals that will trigger the differentiation process.

3 believe they are important regulators of the differentiation process.

4 multiple epigenomic marks during a cellular differentiation process.

5 luripotent cells, which decreased during the differentiation process.

6 STAT4 signaling pathway during the early Th1 differentiation process.

7 genes are coordinately regulated during the differentiation process.

8 increase dramatically and rapidly during the differentiation process.

9 dykinin in the middle and late stages of the differentiation process.

10 ession of TRIB3 in these cells inhibited the differentiation process.

11 criptional regulators of the human monocytic differentiation process.

12 hly dynamic and gradually expands during the differentiation process.

13 anscript during the first 4 days of the hESC differentiation process.

14 lities offer a clonal perspective of the HSC differentiation process.

15 ed by decidual laminins, also inhibited this differentiation process.

16 for predetermination of cell fate during the differentiation process.

17 ll interfering RNAs against FA2H inhibit the differentiation process.

18 modifications occurred throughout the entire differentiation process.

19 rved in cells at the beginning or end of the differentiation process.

20 icroRNAs at every stage of the mature B-cell differentiation process.

21 cycle regulation for mESCs to enter into the differentiation process.

22 n expression on the cell surface during cell differentiation process.

23 inhibitor, to these mice blocked the stromal differentiation process.

24 the cerebral cortex might be involved in the differentiation process.

25 and these genes are downregulated during the differentiation process.

26 ghtly regulated with the host cell cycle and differentiation process.

27 ble but also biologically relevant to muscle differentiation process.

28 ges, although MyoD is present throughout the differentiation process.

29 ance of its stringent regulation during this differentiation process.

30 cement of Wnt4 expression and stimulated the differentiation process.

31 ssion in these cells efficiently blocked the differentiation process.

32 icated they are likely to be involved in the differentiation process.

33 ted cells occurred through a Notch-dependent differentiation process.

34 rentiation are expressed during the terminal differentiation process.

35 sequential passage of the cells through the differentiation process.

36 mad4 by RNA interference inhibited the trans-differentiation process.

37 molecules and cytokine receptors direct the differentiation process.

38 ndependent HIF functions are crucial to this differentiation process.

39 protein expression and an attenuation of the differentiation process.

40 signaling mechanisms that participate in the differentiation process.

41 c cells, nuclear Tmod may be involved in the differentiation process.

42 /EBPbeta expression and in turn initiate the differentiation process.

43 derstanding the mechanisms that regulate the differentiation process.

44 e the expression of BMP4 and DCN during this differentiation process.

45 death stimuli is an implicit feature of the differentiation process.

46 that are regulated in the early phase of the differentiation process.

47 tributable to a delay in the timing of their differentiation process.

48 d new insights into the complex postsynaptic differentiation process.

49 s of a polysaccharide as part of a patterned differentiation process.

50 regions that support different phases of the differentiation process.

51 und that this change was a final step in the differentiation process.

52 Skeletal myogenesis is a well-studied differentiation process.

53 erentiating myoblasts and by maintaining the differentiation process.

54 is required to act downstream of E2F4 in the differentiation process.

55 evaluate regulatory factors involved in this differentiation process.

56 the ligand is present from the onset of the differentiation process.

57 agment that was robustly induced during this differentiation process.

58 and up-regulation of Smad7 could inhibit the differentiation process.

59 ytokine staining at various times during the differentiation process.

60 P activation of TRIP-1 evokes a TGFbeta-like differentiation process.

61 e ability of 1,25(OH)(2)D(3) to alter the Th differentiation process.

62 n CIITA-deficient CD4 T cells during the Th1 differentiation process.

63 ng a role for LXR-dependent signaling in the differentiation process.

64 nimal promoter during the early phase of the differentiation process.

65 ast, are normally incapable of reversing the differentiation process.

66 eurons in cell culture throughout the entire differentiation process.

67 establishing ordered structures along their differentiation process.

68 rs are coordinated and integrated during the differentiation process.

69 ency and regulate gene expression during the differentiation process.

70 er regulatory relationships specific to this differentiation process.

71 , to model regulatory networks specific to a differentiation process.

72 rtant role as a coregulator of the erythroid differentiation process.

73 oRdelta, which appears to help regulate this differentiation process.

74 s essential for this crossover/non-crossover differentiation process.

75 r checkpoint in the T(CM) to T(EM) phenotype differentiation process.

76 for hypothesis generation of underlying ESC differentiation processes.

77 se epidermis impaired both proliferation and differentiation processes.

78 almost exclusively involved in morphogenetic differentiation processes.

79 nderlie cell fate establishment and terminal differentiation processes.

80 fy essential regulators of complex mammalian differentiation processes.

81 ds generated crust and underwent large-scale differentiation processes.

82 rocks reflects 146Sm decayand earlyplanetary differentiation processes.

83 k of requirement for HMGN1 in these cellular differentiation processes.

84 teasome in controlling the proliferation and differentiation processes.

85 ly underlie these endothelial patterning and differentiation processes.

86 r 1 (Tcf1) is essential for several of these differentiation processes.

87 ling, muscle contraction, cell migration and differentiation processes.

88 transformation usually inhibits normal cell differentiation processes.

89 tors are involved in a variety of growth and differentiation processes.

90 ics in regulating stem cell self-renewal and differentiation processes.

91 oth during development and in adult cellular differentiation processes.

92 genetic pathways governing various cellular differentiation processes.

93 rocess neodymium in the Earth, and not early differentiation processes.

94 r state by inhibiting the plasticity of cell differentiation processes.

95 transcription factors activate a variety of differentiation processes.

96 of core formation and other early planetary differentiation processes.

97 tive and quantitative monitoring of neuronal differentiation processes.

98 essors with crucial roles in development and differentiation processes.

99 fferentiation is closely related to neuronal differentiation processes.

100 pects of development, embryogenesis and cell differentiation processes.

101 as drivers of multiple Notch-mediated immune differentiation processes.

102 play key roles in P. patens development and differentiation processes.

103 g with gene transcription to define cellular differentiation processes.

104 s seed formation is coupled with two plastid differentiation processes.

105 of mRNAs that characterize each stage in the differentiation process, (2) that gene expression can be

106 ADAM 12 is up-regulated at the onset of the differentiation process, ADAM 12-mediated activation may

107 entiation but were essential to complete the differentiation process and drive migration of maturing

108 1 (CRLF1), which is up-regulated during the differentiation process and has been previously implicat

109 to the promoters of RFGs coincides with the differentiation process and is attenuated once renal epi

110 in gene expression is initiated early in the differentiation process and is maintained until terminal

111 itries that are controlled by RNA during the differentiation process and that, when deregulated, lead

112 f great interest to understand the bacteroid differentiation process and the roles of energy storage

113 ely expressed at restricted times during the differentiation process and used differential display re

114 tigate the relationships between alternative differentiation processes and pattern formation processe

115 R protein expression was enhanced during the differentiation process, and coincubation with its ligan

116 ic cell concentrations, robust regulation of differentiation processes, and robust pulses of cells or

117 Central to this differentiation process are epigenetic modifications wit

118 gnal transduction mechanisms that drive this differentiation process are still not fully understood.

119 These differentiation processes are associated with restricted

120 These carefully regulated differentiation processes are controlled by networks of

121 Thus, some of the fiber differentiation processes are likely mediated by RTK-dep

122 r, the molecular mechanisms underlying these differentiation processes are poorly understood.

123 and priming, suggesting that these divergent differentiation processes are programmed soon after the

124 EKLF also plays a role during the subsequent differentiation process, as it induces p21(WAF1/CIP1) ex

125 WAF) and p27(Kip), were monitored during the differentiation process, as were levels and activities o

126 monolayer systems that fail to reproduce the differentiation processes associated to multilayered sys

127 he molecular signals that drive the synaptic differentiation process at individual synapses in the ce

128 The increased cycling reflects the perturbed differentiation process, because Id1 null HSCs more read

129 corin, an anti-fibrosis agent, prevents this differentiation process by blocking TGF-beta1.

130 Reducing the stochastic effects of the differentiation process by correcting for cell type comp

131 he Hdac inhibitors, (ii) facilitation of the differentiation process by overexpression of the N-termi

132 Akt1 and Akt2 also contribute to the differentiation process by promoting the survival of the

133 To the extent that their fate choice and differentiation processes can be understood and manipula

134 These results suggest that during the early differentiation process CD4 T cells acquire a mixed Th1/

135 Throughout this stepwise differentiation process, changes in anterior neural, ret

136 + cells mechanical properties throughout the differentiation process could enable development of new

137 clude regulators of migration, apoptosis and differentiation, processes crucial for normal developmen

138 e bacteria undergo a host-directed multistep differentiation process culminating in the formation of

139 onal development includes altered maturation/differentiation processes, disturbances in cell-cell com

140 AR3 may antagonize AR activity and halt the differentiation process driven by AR and androgen.

141 Megakaryocytopoiesis is a complex differentiation process driven by the hormone thrombopoi

142 Myogenesis is a tightly regulated differentiation process during which precursor cells exp

143 Cellular differentiation processes during normal embryonic develo

144 en Notch and EGFR signaling that governs the differentiation processes during this period.

145 ssentially every developmental checkpoint or differentiation process encountered by lymphocytes.

146 a selective role for TAF8 in a specific cell differentiation process(es).

147 Through an unusual differentiation process examined in this review, these f

148 Muscle tissue in the early stages of the differentiation process exhibited distinctly higher T1 (

149 Thus, in a late cellular differentiation process, Foxp3 defines Treg cell functio

150 ninvasive in vivo monitoring of the myogenic differentiation process from muscle precursor cells to m

151 This differentiation process from Sox10(+) stem cells to myof

152 time-lapse video microscopy of the stepwise differentiation processes from single progenitors.

153 eby KLF4 regulates genes associated with the differentiation process has not been studied.

154 imuli and the importance of C/EBPbeta to the differentiation process have led us to hypothesize a rol

155 While key differentiation processes have been characterized at the

156 nd pairs that act in the context of specific differentiation processes have been described.

157 Through an unusual differentiation process, human trophoblast progenitors (

158 Within 2 h of initiation of the differentiation process, HuR complexes containing C/EBPb

159 y human development, we closely examined the differentiation process in adherent colonies of human em

160 t are activated sequentially and control the differentiation process in an overlapping manner.

161 TCR-mediated stimulation to induce the same differentiation process in both immature CD2(-/low) and

162 otch signalling is a key event in the normal differentiation process in breast tissue.

163 critical upstream regulatory role in the mDA differentiation process in human pluripotent stem cells.

164 d 1,25-dihydroxy-vitamin D3 that promote the differentiation process in keratinocytes.

165 tial molecular regulators in vitro of the NE-differentiation process in lung cancer.

166 n human neurogenesis, we compared the neural differentiation process in mesenchymal stem cells (MSCs)

167 cyte differentiation in vivo we examined the differentiation process in mice null for the expression

168 roles in many cell processes, including the differentiation process in several different lineages.

169 g that SOCS-3 can contribute to the myoblast differentiation process in the absence of IGF-I.

170 took advantage of the local synchrony of the differentiation process in the paraxial mesoderm.

171 arkers for the analysis of determination and differentiation processes in complex epithelia, such as

172 Ps) are secreted growth factors that promote differentiation processes in embryogenesis and tissue de

173 are essential for pattern formation and cell differentiation processes in mammals.

174 Notch signaling controls diverse eukaryotic differentiation processes in multiple cell types, thus d

175 cal mechanisms that underlie development and differentiation processes in the Drosophila embryo.

176 There is growing evidence that the differentiation processes in the fetal and adult thymus

177 NT2-mediated regulation of proliferative and differentiation processes in the smooth muscle and may b

178 s involved in embryogenesis, development and differentiation processes in vertebrates.

179 ing signaling molecules that can guide these differentiation processes in vitro, and will be describe

180 As can exert critical control over mammalian differentiation processes in vivo.

181 nderstanding the molecular mechanisms of the differentiation process, in particular neuroendocrine (N

182 highlighted its putative function in neural differentiation processes, including axon guidance as su

183 t revealed a transcriptional reversion of CM differentiation processes, including reactivation of lat

184 1 cells, a physiological C/EBPbeta-dependent differentiation process indicating that the cooperation

185 be important for cell cycle progression and differentiation processes indicating that a complex netw

186 Furthermore, PPARgamma agonists enhanced the differentiation process initiated by ET-743.

187 olecular effectors involved in executing the differentiation process initiated by TCR-ligand interact

188 ns directly affects flocculation, a cellular differentiation process initiated under conditions of nu

189 CD8 T cells undergo expansion and a dynamic differentiation process into functionally different subp

190 34+ cells, and expelled nuclei, during their differentiation process into red blood cells at days 11,

191 rce of metastatic progenitor cells through a differentiation process involving EMT and mesenchymal-ep

192 etween survival metabolism and growth and/or differentiation processes involving cellulose synthesis.

193 We further show that the differentiation process is associated with a striking mo

194 The glial differentiation process is characterized by a marked dow

195 antitative analysis shows that the endocrine differentiation process is consistent with a simple mode

196 In vitro, this differentiation process is facilitated by confluency, fo

197 occurs in the presence of TRAP and that the differentiation process is mediated through the Smad2/3

198 contrast, in ulcerative colitis, a Th2-like differentiation process is paramount, which results in e

199 Regulation of this differentiation process is poorly understood, but involv

200 This differentiation process is tightly controlled by exogeno

201 lecular functions and its roles in any given differentiation process is unknown.

202 The differentiation process is very costly and time-consumin

203 -like peptide (ILP) signaling in sex-related differentiation processes is attracting increasing atten

204 enetic enzymes contribute to development and differentiation processes is largely unclear.

205 An essential feature of the differentiation processes is the assembly of a rigid, ce

206 idermis forms during the course of a complex differentiation process known as cornification, which cu

207 ukemia (AML) is characterized by an impaired differentiation process leading to an accumulation of im

208 obium microsymbionts undergo an irreversible differentiation process leading to the development of el

209 , underwent cell differentiation in vivo The differentiation process led to suppression of p63-expres

210 ach cell line proceeded to completion of the differentiation process like the wild-type cells with th

211 networks using expression data observed in a differentiation process may help identify context-specif

212 Abnormalities of this differentiation process may underlie development of some

213 e degeneration occurs due to an osteoblastic differentiation process mediated by the low-density lipo

214 prevented premature initiation of the fiber differentiation process mediated by the NAC SECONDARY WA

215 ing-dependent systems, such as the epidermal differentiation process, must effectively respond to var

216 on changes in two divergent terminal myeloid differentiation processes, namely MAC and OC differentia

217 and performed a comparative study during the differentiation process, observing significant differenc

218 Simultaneously, a dynamic differentiation process occurs, resulting in the formati

219 on persists concerning their function in the differentiation process of cardiomyocytes.

220 alt and sour, and recapitulate the molecular differentiation process of endogenous taste buds.

221 application toward our understanding of the differentiation process of iPSCs toward hematopoietic pr

222 dermal barrier defects caused by an aberrant differentiation process of keratinocytes are comparably

223 These results thus suggest a delay in the differentiation process of Klhl6-deficient B cells betwe

224 d Wnt signaling likely regulates the overall differentiation process of nail/claw formation.

225 rn of connectivity are likely to control the differentiation process of newly generated neurons and e

226 anscription factors that are involved in the differentiation process of numerous tissues, including t

227 data demonstrate a key role for Rsk1 in the differentiation process of PC12 cells.

228 fied may improve our understanding of the de-differentiation process of prostate tumors.

229 the expression and function of Ascl1 in the differentiation process of specific neuronal subtypes du

230 a(z) into PC12 cells markedly attenuated the differentiation process of these cells induced by a cAMP

231 dying the mechanism involved in the terminal differentiation process of these postmitotic cells.

232 ide key insights into poorly understood cell differentiation processes of considerable physiologic re

233 terogeneity truly recapitulates multilineage differentiation processes of normal tissues remains unkn

234 twork (GRN) regulating the specification and differentiation processes of pigment cells, we experimen

235 rogress in understanding its precise role in differentiation processes of the mature peripheral immun

236 the epigenetic mechanisms that program this differentiation process on a genome-wide scale are large

237 gonistic factors at low levels, early in the differentiation process or in pluripotent stem cells, co

238 ific to adipogenesis, as another mesenchymal differentiation process, osteoblastogenesis, is enhanced

239 hepatocytes, despite being far along in the differentiation process, possess the capacity for extens

240 cells with cathepsin B inhibitors during the differentiation process reduces cell fusion and bone res

241 Megakaryopoiesis is a 2-step differentiation process, regulated by thrombopoietin (TP

242 Adipogenesis is a key differentiation process relevant to obesity and associat

243 t the downstream target genes regulating the differentiation process remain largely unknown.

244 or populations at intermediate stages of the differentiation process remain to be established.

245 les in the mucosal defense system, but their differentiation process remains poorly understood.

246 however, the molecular mechanism behind this differentiation process remains unclear.

247 This differentiation process required Wt1 expression in this

248 ession during macrophage and oligodendrocyte differentiation, processes requiring membrane growth.

249 liferation of keratinocytes and the terminal differentiation process, resulting in an in vivo-like mo

250 tor requirement controlling each step of the differentiation process, resulting in the production of

251 Live imaging of the differentiation process reveals that cells on the outer

252 me binucleate as they complete the 'terminal differentiation' process soon after birth and are not ab

253 spermatogenesis is an elaborately organized differentiation process, starting with diploid spermatog

254 cell structure, motility, transport and cell differentiation processes such as sporulation, heterocys

255 nonosteoblastic cells without activating the differentiation process, suggesting that its activity is

256 ished by reversing the natural developmental differentiation process, suggesting that the two mechani

257 differences and may arise from activation or differentiation processes taking place in the cells.

258 We have developed a differentiation process that converts human embryonic st

259 marrow myeloid progenitor cells by a complex differentiation process that culminates in fusion of mon

260 hese cells must undergo a targeted, stepwise differentiation process that follows a normal developmen

261 lial-to-mesenchymal transition (EMT) is a de-differentiation process that has been implicated in meta

262 stem cells give rise to all blood cells in a differentiation process that involves widespread epigeno

263 a novel role of iron in modulating a B cell differentiation process that is critical to the generati

264 ell type, called a spore, during a multistep differentiation process that is initiated in response to

265 Endomitosis is a unique megakaryocyte (MK) differentiation process that is the consequence of a lat

266 These data suggest a differentiation process that orchestrates the vasculariz

267 teins will help to elucidate the presynaptic differentiation process that ultimately leads to synapse

268 standing of the melting, melt-extraction and differentiation processes that intervene between the mag

269 endochondral ossification are the cartilage differentiation processes that lead to skeletal formatio

270 eration of fibroblasts and myofibroblasts by differentiation processes that require extensive alterat

271 g protein 1) that are critical to the B cell differentiation processes that underpin Ab and autoantib

272 Thus, plastids in the SAM undergo distinct differentiation processes that, depending on their linea

273 cells followed by the execution of myogenic differentiation, processes that are coordinated by myoge

274 as levels of E1 remained constant during the differentiation process, the levels of ubiquitin-conjuga

275 st be in part a consequence of shallow-level differentiation processes, though such processes remain

276 II collagen, are degraded at the end of the differentiation process through induction of matrix meta

277 face reconstituted epithelium throughout the differentiation process to 21 days.

278 ce in macrophage activity is the result of a differentiation process to either M1 or M2 phenotypes.

279 ailability, this organism undergoes a simple differentiation process to form cysts that are resistant

280 in actively repressing effector or terminal differentiation processes to promote memory CD8(+) T cel

281 n, it is often necessary to compare multiple differentiation processes triggered by different externa

282 an generate some CD80(+) mTECs in a stepwise differentiation process via YFP(-)Ly51(low)CD80(low) int

283 STAT3 promoted THi development, whereas this differentiation process was greatly impaired in STAT3-de

284 o of Ig L chain usage indicated that a local differentiation process was taking place in arterial wal

285 The role of SOX18 in the differentiation process was validated by using lineage-t

286 the role of Wnt signalling in regulating the differentiation process we manipulated key nodes of this

287 chanisms that orchestrate the stage-specific differentiation process, we developed a computational fr

288 o determine the function of BMP2 during this differentiation process, we employed a primary culture s

289 the function of specific PKC isotypes in the differentiation process, we employed an established mode

290 To assess mechanisms underlying this differentiation process, we searched for muscle specific

291 esponsiveness is set only during the NK cell differentiation process, we transferred mature NK cells

292 At three time points during this differentiation process, we used high-throughput sequenc

293 refore investigated whether defects in these differentiation processes were due to an inability to im

294 ling dynamic networks is applicable to other differentiation processes where time-course genome-scale

295 ls, resulting in defects in cell renewal and differentiation processes which lead to malignancy.

296 ity to receptor-mediated apoptosis along the differentiation process, which becomes the major mechani

297 d glucocorticoid hormones during the cardiac differentiation process, which when coupled with further

298 data provide new insights on the chromoplast differentiation process while enriching our knowledge of

299 tion and de novo occupation occur during the differentiation process, with higher overall nucleosome

300 les to function as molecular switches in the differentiation process without tipping the balance towa