ライフサイエンスコーパス: diffusional

1 g process, involving transcriptional status, diffusional ability of chromatin, and physical interacti

2 at small molecules such as O(2) have similar diffusional access to the complexed HYP in each of the p

3 We model both diffusional and conformational fluctuations in a Langevi

4 ential for achieving a high throughput rate, diffusional and dissipative dynamical factors must also

5 , while the 'primed' unbound state is highly diffusional and only weakly biased to step towards the M

6 namical states including epochs of directed, diffusional, and stalled motion.

7 roteins can refine coarse-grain estimates of diffusional anisotropy for adenine nucleotides in the ca

8 these by the model-free formalism with axial diffusional anisotropy further reveal significant ms to

9 ease macromolecular diffusivity and increase diffusional anisotropy in a site-specific manner that de

10 fusivity decreased by 0.16 in all zones, and diffusional anisotropy increased 1.1-fold in the surface

11 of the half-sarcomere further suggests that diffusional anisotropy may lead to modest adenine nucleo

12 ching, to measure diffusion coefficients and diffusional anisotropy of 70 kDa dextran in cartilage du

13 ordered tissues such as articular cartilage, diffusional anisotropy was dependent on site in the tiss

14 oint photobleaching was developed to measure diffusional anisotropy.

15 This resulted in a significant increase in diffusional anisotropy.

16 cular dynamics (MD) simulations and implicit diffusional approaches.

17 enerally uses monoexponential fitting of the diffusional attenuation of pulsed-field gradient stimula

18 he more mature calyx, there is a far smaller diffusional barrier attributable to the highly fenestrat

19 omodulators, the hydrophilic cytosol poses a diffusional barrier for the efficient delivery of AEA to

20 This method uses the design of a diffusional barrier to increase the resolution that can

21 l, a prototypic metabolic sensor, revealed a diffusional barrier within the submembrane space, preven

22 the advancing phagocytic cup by an expanding diffusional barrier.

23 een amply documented and discuss the role of diffusional barriers and other processes in the generati

24 l environment, phosphotransfer systems shunt diffusional barriers and secure regimented signal transd

25 is not well understood, but the existence of diffusional barriers has been proposed.

26 nitric oxide, 2) show that extra-erythocytic diffusional barriers mediate most of this effect, and 3)

27 ecific locations on membranes and by forming diffusional barriers that restrict lateral diffusion of

28 by acting as molecular scaffolds and forming diffusional barriers.

29 solution, She1 binds tightly to and exhibits diffusional behavior along microtubules.

30 study provides a comparative picture of the diffusional behavior in both environments.

31 Upon degradation of the actin skeleton, the diffusional behavior in the plasma membrane was strongly

32 mparison with unfixed control proteins whose diffusional behavior may or may not differ from that of

33 From the diffusional behavior of nanoparticles in heterogeneous h

34 ization occurs at spine heads because of the diffusional bottleneck created by the spine neck.

35 ng step is the diffusion through the aqueous diffusional boundary layer.

36 ake process is diffusion through the aqueous diffusional boundary layer; as such, the overcoated PDMS

37 To overcome the diffusional broadening and have a mobility based resolut

38 k for the quantitative interpretation of the diffusional broadening and the apparent molar mass value

39 ovides a high hydrodynamic resolution, where diffusional broadening of the sedimentation boundaries i

40 emporal response and significantly decreases diffusional broadening of the signal in FEEM as compared

41 on mobility spectrometers, in particular (a) diffusional broadening which leads to degradation of ins

42 istances within the flow tubes, with minimal diffusional broadening, is demonstrated using an ultrami

43 and t(-1/2), as prescribed for instrumental (diffusional) broadening.

44 heless, and somewhat counterintuitively, the diffusional Brownian motion determines the fundamental l

45 This contribution exceeds that due to diffusional Brownian motion during the passage.

46 lectrolytes to the anodic enzyme and the gas-diffusional cathode design provides the passive supply o

47 lation spectroscopy (FCS) to investigate the diffusional characteristics of functional agonist-occupi

48 local chain conformational properties, local diffusional characteristics, and phase discrimination af

49 Interestingly, all four chimeras had similar diffusional characteristics, approximately 45% of each c

50 cross-linked dimers are formed during random diffusional collisions.

51 Furthermore, the recent observation of diffusional "compartmentalization" has suggested that di

52 n reduced the cytoplasmic, but not membrane, diffusional component of NBD-stearic acid movement 2-fol

53 ep size and direction suggest a considerable diffusional component to its step, which differs from Ki

54 Lung and muscle O2 diffusional conductances were computed from these measur

55 depend on the ratio of the surface and bulk diffusional constants, pK(a) values of surface protolyti

56 ed heterogeneous catalysts are free from the diffusional constraints placed on all known porous solid

57 b initio calculations, taking into account a diffusional contribution according to the encounter pair

58 Diffusional contributions are taken into account using t

59 spine neck during spine motility alters the diffusional coupling between spine and dendrite and sign

60 explained by heterogeneity in spine sizes or diffusional coupling between spines and their parent den

61 We found that spine/dendrite diffusional coupling is heterogeneous and uncovered a cl

62 The regulation of diffusional coupling provides a possible mechanism for d

63 limits for nanocrystal stability by surface diffusional creep and dislocation plasticity, respective

64 n map delineating the predominant regimes of diffusional creep at low stress and high temperature and

65 stalline order and lead to processes such as diffusional creep, sliding and rotation.

66 crystal slip serves as a stimulus to surface diffusional creep.

67 ndary, rather than grain boundary sliding or diffusional creep.

68 esonance method for acquiring and displaying diffusional data that defines highly ordered myofiber pa

69 Since diffusional delivery of substances will not induce appre

70 bly and de novo reassembly model and the non-diffusional displacive model.

71 because it regulates the bioavailability and diffusional distance of endothelial-derived NO.

72 cell densities creating prohibitively large diffusional distances for nutrients.

73 rriers are significant and varied; increased diffusional distances, elevated interstitial fluid press

74 t this cofactor activity is limited to short diffusional distances.

75 kage between coenzyme binding energetics and diffusional domain motion impinges directly on the molec

76 prising odd-even effect in the translational diffusional dynamic properties of n-alkanes in their liq

77 y condition, a source for supplying internal diffusional dynamics.

78 e resultant thin-layer voltammogram shows no diffusional effect, which simplifies the theoretical mod

79 iers, and geometries, as well as kinetic and diffusional effects, providing a tool for hypothesis tes

80 Our measures of diffusional efficiency are shown to decrease as a functi

81 diated PG uptake, cytoplasmic oxidation, and diffusional efflux of the PG metabolite.

82 complementary AFM measurements to probe the diffusional electroactivity of AQDS.

83 tate ion-pair, [C1(2+), I(-)](+*), underwent diffusional electron-transfer oxidation of iodide that d

84 ed reactions (where the rates of the initial diffusional encounter and of structural fluctuations det

85 is indicates that electrostatics control the diffusional encounter but not the dissociation rate, whi

86 m, whereby proteins are pre-aligned in their diffusional encounter by long-range electrostatic attrac

87 h response onset and recovery are set by the diffusional encounter frequency between proteins on the

88 ctions of EXO substrates are rate limited by diffusional encounter of enzyme and substrate, explainin

89 itions that are slow on the timescale of the diffusional encounter of noninteracting FAS2 and AChE.

90 We are able to rule out diffusional encounter of O(2) with protein, an outer-sph

91 This value approaches that expected for the diffusional encounter of the enzyme and its substrate.

92 quasi-kinetic search process to emulate the diffusional encounter of two proteins and to identify lo

93 he native dimer hydrolyzes multiple ATPs per diffusional encounter with an actin filament.

94 larger cell surface would make recapture by diffusional encounter with the endocytic retrieval machi

95 We propose that before diffusional encounter, the ensemble of accessible confor

96 s by enhancing the rate of success of random diffusional encounters but also play a role in protein f

97 was estimated to be longer than the time for diffusional encounters with other oligomers at typical c

98 complex mechanism than simple restriction of diffusional entry and exit from the active center.

99 did not affect entry of membrane proteins or diffusional entry of small cytosolic proteins.

100 alytic throughput (k(cat)/K(m)) and rates of diffusional entry of trifluoroketones to the active cent

101 reakpoint of the decay kinetics demonstrates diffusional equilibration between spine and dendrite dur

102 A and AMPA receptors and is followed by fast diffusional equilibration within the spine head.

103 Ions with these short lifetimes are not in diffusional equilibrium with nonsolvent nucleophiles, an

104 Thus, a diffusional event is coupled to the chemical step of Ado

105 structural properties (using stereology) and diffusional exchange characteristics (using measurement

106 is known about the structural development or diffusional exchange characteristics of the Igf2null(+/-

107 cental Igf2 regulates the development of the diffusional exchange characteristics of the mouse placen

108 uctions in its cellular compartments and its diffusional exchange characteristics.

109 nstrate that local synaptic activity reduces diffusional exchange of GluR1 between synaptic and extra

110 aqueous gap junction channels that allow the diffusional exchange of ions and small metabolites betwe

111 When ER topology is altered, the long-range diffusional exchange of proteins in the ER network and t

112 ee STIM1 and Orai1, which engage in constant diffusional exchange with extrajunctional pools.

113 enomena, highlighting proton chemical and/or diffusional exchanges between water and starch.

114 The diffusional exponent (n) values of Peppas equation expla

115 or being affected by the overlapping of the diffusional fields without previous considerations.

116 ffect with the consequent overlapping of the diffusional fields.

117 rofiles in the rock matrix and the estimated diffusional flux from the rock matrix suggest that the e

118 Thermophoresis is the directed net diffusional flux of molecules and colloidal particles in

119 Also the diffusional flux of P as measured with the DGT technique

120 ts total concentration change is dictated by diffusional fluxes into and out of the interface.

121 rge-scale DNA motions through reports of the diffusional freedom of a single fluorophore.

122 in Au-IO films stems from the generation of diffusional gradients within the pores of the mesostruct

123 show a general approach for rapid control of diffusional growth through nanoparticle self-assembly on

124 The detection is based on diffusional hindrance by the insulating objects which al

125 The greater diffusional hindrance in DC tumors was correlated with h

126 The diffusional hindrance of the glycocalyx along the cell s

127 lons to the tubular ER, as well as for their diffusional immobility and oligomerization.

128 an diffusion in resting receptors but nearly diffusional in active receptors; (iii) whereas resting a

129 f Drosophila early embryos, characterized by diffusional interactions and weak binding, differing fro

130 It was found that diffusional interactions between the tip and the substra

131 icrom above a biological cell, tip-substrate diffusional interactions were greatly diminished at a sc

132 pK(a) values, self-assembly equilibria, and diffusional kinetics.

133 of apparent diffusion coefficient (ADC) and diffusional kurtosis (K) were derived by using maximal b

134 uctural asymmetry with tractography based on diffusional kurtosis imaging (DKI), which improves upon

135 Diffusional kurtosis imaging (DKI), which measures the n

136 rostructural changes along WM pathways using diffusional kurtosis imaging (DKI).

137 s derived from a two-compartment WM model of diffusional kurtosis imaging (WM-DKI), including intra-a

138 Diffusional kurtosis showed different spatiotemporal dyn

139 h due to influence of neighboring cells, and diffusional lag times.

140 ese signals combine to create spatiotemporal diffusional landscapes that precisely regulate the devel

141 d us to investigate fast reactions up to the diffusional limit including reactions of highly reactive

142 Adipocytes can rapidly reach the diffusional limit of oxygen during growth; hypoxia is th

143 attraction decreases the bundling time to a diffusional limit, which is determined by the capture cr

144 raditional methods for encapsulation lead to diffusional limitations imposed by the size of the capsu

145 solution value) is observed, consistent with diffusional limitations on substrate access to the enzym

146 combustion reactions place heavy emphasis on diffusional limitations, as reaction scales become comme

147 ty in reactions suffering from steric and/or diffusional limitations.

148 fused membranes is obtained by studying the diffusional lipid dynamics with fluorescence recovery af

149 KPS method, thus facilitating prediction of diffusional loss and penetration of gases and particles,

150 Diffusional loss of analyte into the confining layer was

151 ng of DADMe-ImmH is 50-fold more likely than diffusional loss of the inhibitor from the erythrocyte.

152 apturing inhibitor molecules is greater than diffusional loss to the extracellular space.

153 ed to the microbead forming solution however diffusional losses of riboflavin occurred during the sub

154 -core silica materials providing the shorter diffusional mass transfer path for solutes are less affe

155 The transition between diffusional mass transport and thin-layer regime is desc

156 ower concentrations is chiefly controlled by diffusional mass transport from the solution to the sens

157 ase the quenching is dominated by a dynamic (diffusional) mechanism.

158 Diffusional membrane permeability (P(d)) for the Xenopus

159 The diffusional merge of these oppositely supercoiled domain

160 by the use of a novel microscopic tool, the diffusional microburet (DMB), suitable for fine chemical

161 ivery of molecules into single cells using a diffusional microburet, DMB.

162 and subtraction of absorbing molecules with diffusional microburets (DMBs), as well as more complex

163 Diffusional migration of SSB helps in the local displace

164 uids to diffraction-limited dimensions where diffusional mixing is rapid and efficient.

165 ing time of 12 mul liquids from 170 min, for diffusional mixing, to less than 23 s.

166 recovery after photobleaching to measure the diffusional mobilities of chimeras consisting of green f

167 We then studied the diffusional mobilities of emerin, MAN1, and LBR using fl

168 In cells loaded with excess cholesterol, the diffusional mobilities of GFP-HRas, GFP-NRas, and GFP-KR

169 Consistent with this finding, the diffusional mobilities of tumor-derived sequence-specifi

170 studied their intracellular localization and diffusional mobilities using fluorescence recovery after

171 R3 mobility may be higher than its intrinsic diffusional mobility because of additional ATP- and micr

172 of the attendant, radically enhanced, atomic diffusional mobility inside actively deforming shear ban

173 , our results suggest that the regulation of diffusional mobility is induced by a reduction in cell v

174 ion and/or aggregation, we have measured the diffusional mobility of green fluorescent protein (GFP)

175 We measured the diffusional mobility of human CFTR in the plasma membran

176 lesterol loading) had similar effects on the diffusional mobility of raft and nonraft proteins.

177 Accelerated diffusional mobility of raft-associated lipids was shown

178 onded to ER cholesterol changes with altered diffusional mobility, suggesting that erlins themselves

179 he reactive surfaces and a decrease in their diffusional mobility.

180 clear mRNP trafficking are consistent with a diffusional model.

181 terahertz region, where the higher frequency diffusional modes are strongly overlapped with libration

182 n switching K5s between force generation and diffusional modes of MT binding.

183 ge number of contributions ranging from slow diffusional modes to underdamped librations and intramol

184 -headed KIF1A was reported to undergo biased diffusional motion along microtubules.

185 observed sizes for confinement of chromatin diffusional motion are similar to the estimated sizes of

186 cted by the mutations is indeed the relative diffusional motion of the domains.

187 ambient viscosity implies that the tethered diffusional motion of the ISP is part of the rate limita

188 Conversely, at faster scan rates the diffusional motion of the molecule limits the simulated

189 The diffusional motion on the membrane, characterized by sin

190 he relative contributions of vibrational and diffusional motion.

191 systems also exhibit dissimilar traits when diffusional motions and residence times of single constr

192 Large, diffusional motions are often on timescales that are dif

193 t upper limit to folding speed once the bulk diffusional motions become sufficiently rapid.

194 The speed of simple diffusional motions, such as the formation of loops in t

195 ction, which limits opportunities to observe diffusional motions.

196 This observation of diffusional movement of a protein on ssDNA introduces a

197 e synapse, spontaneous activity confines the diffusional movement of GluR1 to restricted subregions o

198 tail-microtubule binding may also influence diffusional movement of kinesin-1 on microtubules, and k

199 errupted with frequent directional switches, diffusional movement, and pauses.

200 un length or any selective inhibition of the diffusional movement.

201 and there was a dramatic 20-fold decrease in diffusional movements of cytoplasmic dynein beads on mic

202 We also observed significant diffusional noise of G-actin monomers, which leads to sm

203 ions demonstrate that under these conditions diffusional overlap between neighboring SWNTs is signifi

204 onal solid metal UMEs (e.g., Pt, Au), due to diffusional overlap between neighboring SWNTs.

205 To limit diffusional overlap of current, only 20-30% of the micro

206 ogically consequential in contexts where the diffusional path of oxygen is not water dominated.

207 tudies were conducted to determine whether a diffusional pathway for solutes exists from the ciliary

208 consistent with the existence of an anterior diffusional pathway in the human eye.

209 ese bilayers around the gA channel creates a diffusional pathway next to the mouths of the channel th

210 e mesoporous zeolitic materials that combine diffusional pathways on two different size scales.

211 eld glued bilayers of 2 and 3 having similar diffusional pathways, as judged by He/N2 selectivities.

212 en transversal and longitudinal sarcoplasmic diffusional pathways.

213 ution by reducing the detrimental effects of diffusional peak broadening and increasing peak widths.

214 tion, and a triangular peak when there is no diffusional peak broadening.

215 True water diffusional permeability (2.7 +/- 0.4 microm/s) is shown

216 shown to be 39 +/- 6% greater than apparent diffusional permeability for 8 oocytes.

217 omoter (P0) regulates the development of the diffusional permeability properties of the mouse placent

218 vesicles showed that glucagon increased the diffusional permeability to the ammonia analog [(14) C]m

219 meability may be referred to as the apparent diffusional permeability, P, to acknowledge this potenti

220 late intracellular lifetime to true membrane diffusional permeability.

221 s suggest that HIV maturation involves a non-diffusional phase transition in which the detaching laye

222 s application owing to its dependence on the diffusional potentials of inorganic ions.

223 For example, the promotion of diffusional problems (e.g., pH gradients, substrate or p

224 However, to establish what diffusional process is the bottleneck for Li-ion transpo

225 displacive deformation, is accomplished via diffusional process mainly, due to the high homologous t

226 is not hydride transfer and must be either a diffusional process or a conformational change.

227 Because the rate of a diffusional process such as protein folding is controlle

228 h the TiO(2)-anatase crystal, an anisotropic diffusional process that can be up to an order of magnit

229 e and guanidine penetrate the BBB by a minor diffusional process with no appreciable transport via sa

230 asing plasma ALA concentrations suggesting a diffusional process.

231 t inhibitor) and, therefore, appears to be a diffusional process.

232 nding proteins, and intra- and intercellular diffusional processes.

233 ke by cells most likely arises from passive, diffusional processes.

234 Measurements of diffusional properties as a function of viscosity and pr

235 cal conductivity to link the latter with the diffusional properties of TATS.

236 imaging to characterize the organization and diffusional properties of the PM in the early embryonic

237 valuate, quantify and map heterogeneities in diffusional properties within complex hierarchically por

238 es are known to affect protein stability and diffusional properties.

239 lso been developed to elucidate chemical and diffusional proton exchange phenomena, and to improve th

240 del compound, trimethylpyruvate, to act as a diffusional quencher of indole fluorescence in solution.

241 The first involves diffusional quenching of the excited state by Br(-) with

242 decomposition of the current into transient diffusional, radial convectional, and axial convectional

243 s 10 times that for alpha-D-glucose, and the diffusional rate constants should be essentially the sam

244 ibe new, molecular-surface-based models, for diffusional reaction boundary criteria and compare resul

245 ferritic alloy, is effective in reducing the diffusional relaxation along the interface between the p

246 Viscosity experiments suggest that diffusional release of product is not rate-determining f

247 We also constrain the molecular diffusional resistance above the ocean surface-an import

248 xidative phosphorylation, increased cellular diffusional resistance and inhomogeneities in oxygen sup

249 alculated charge transfer resistance and the diffusional resistance components is evaluated.

250 hifts in both charge transfer resistance and diffusional resistance.

251 ith the significant coupling between overall diffusional rotation and internal motion expected to exi

252 line array of molecular rotors with inertial diffusional rotation at the nanoscale, characterized by

253 dynamics simulations, indicate that inertial diffusional rotation is characterized by a broad range o

254 fusion of the whole gA dimer, giving rise to diffusional rotation of the dimer about the channel axis

255 th and direction, diffusion sensitivity, and diffusional sampling to determine the optimal achievable

256 In such a membrane-dominated diffusional scheme, the influence of cholesterol on oxyg

257 The strength of diffusional screening is also related to the number of c

258 er relationship supports our hypothesis that diffusional screening is present in this system.

259 o determine whether and if so to what extent diffusional screening may operate in placental villi.

260 le-attached head, the other head undergoes a diffusional search for its next site, the outcome of whi

261 on polymeric surfaces as a means to expedite diffusional search processes in molecular engineered sys

262 al intermediates and reduce the dimension of diffusional search represents a novel and effective mech

263 how Rad4 pauses to recognize lesions during diffusional search, we examine conformational dynamics a

264 within the contact pair becomes slower than diffusional separation (k(-d)), causing deviation from t

265 reaction goes against this proposal, as the diffusional separation of CO(2) would be on the order of

266 ay channel for the geminate radical pairs is diffusional separation to free radicals.

267 associated with covalent bond formation and diffusional separation to the solvent-separated ion pair

268 ates of variable size that segregated due to diffusional sieving of small, mobile M1-AQP4-enriched ar

269 ement this strategy in a native microfluidic diffusional sizing platform, allowing us to achieve dete

270 However, it does not address the diffusional spread of the reaction boundary from the cos

271 d Tbeta4 and the consequent reduction in the diffusional spread of the Tbeta4-actin complex were pred

272 duct reprotonation, respectively, and that a diffusional step, such as substrate binding, may be rate

273 formation/disruption cycles with intervening diffusional steps result in larger DNA loops, leading to

274 Store microanatomy suggests that diffusional strictures may account for this paradox.

275 n of antibiotics in the soil solution, their diffusional supply, and the exchange kinetics between di

276 Herein, we demonstrate that diffusional surface voltammetry (DSV), which embodies fi

277 These Munc18-1 and syntaxin-1A diffusional switches were blocked by the expression of M

278 ional static hybridization, which depends on diffusional target delivery, with signals obtained in a

279 The mean diffusional time constant of the wild type and variants

280 of the pH oscillations was smaller than the diffusional timescale of the particles, whereas disorder

281 ions of BSA or L-FABP, proteins that exhibit diffusional transfer kinetics.

282 nctions at the MEJ was assessed by measuring diffusional transfer of biocytin and Cy3.

283 rane ligand transport was developed in which diffusional transfer of ligand between membrane and prot

284 The ion exchange reaction occurs through diffusional transfer of molecules between the ion exchan

285 lly with the tubulin COOH terminus to permit diffusional translocation of MCAK along the surface of M

286 need to explicitly account for kinetics and diffusional transport (and localization) of enzymes, sub

287 thin such arrays has a significant impact on diffusional transport as the pore size is reduced to the

288 port by Si transporters at low Si(OH)(4) and diffusional transport controlled by the capacity of intr

289 key limiting factors of filopodial length is diffusional transport of G-actin monomers to the polymer

290 These findings suggest that diffusional transport of macromolecules is anisotropic i

291 oscope (SECM-AFM) has been used to probe the diffusional transport of target electroactive solutes in

292 response controlled by the nanopore-mediated diffusional transport of tetrabutylammonium ions to the

293 hought to be much too large to undergo rapid diffusional transport through mucus barriers.

294 can be exchanged across the gel scaffold by diffusional transport.

295 maller than the value predicted for a purely diffusional transport.

296 a nanoscale arrangement that supports rapid diffusional transport.

297 ng sedimentation fluxes with periods of high diffusional transport.

298 Our data suggest that diffusional trapping through protein-protein interaction

299 osmotic fragility of infected cells based on diffusional uptake via PESAC and the two-compartment geo

300 40% compared with WT), and no change in the diffusional water permeability (P(d)).