ライフサイエンスコーパス: digestive

1 te of infection (cutaneous, inhalational, or digestive).

2 Diseases of digestive (110 922; 16%), genitourinary (82 505; 12%), a

3 n the Federation Francophone de Cancerologie Digestive 2000-05 phase 3 trial.

4 ory episodes occurred in 71 patients, mainly digestive (50%).

5 MET-hours/week; 95% CI, 0.51-0.87) than with digestive accessary organ cancers.

6 tomach, small intestine, and colorectum) and digestive accessory organs (pancreas, gallbladder, and l

7 erwise remain inaccessible to the host, such digestive actions alone cannot make up for dietary insuf

8 soforms may compensate for the loss of CELA1 digestive activity in the human pancreas.

9 Here, we resurrect digestive alcohol dehydrogenases (ADH4) from our primate

10 larify the influence of HFD in the motility, digestive and absorptive capacity, and intestinal barrie

11 Resistant starch (RS) has unique digestive and absorptive properties which may provide he

12 SP IgGs in patients with different (cardiac, digestive and asymptomatic) chronic Chagas disease manif

13 ults indicate that A. glabripennis modulates digestive and basal gene expression when larvae are feed

14 Moreover, host-encoded digestive and detoxification mechanisms likely render mi

15 into the intestine and are required for its digestive and endocrine functions.

16 partitioned the element predominantly within digestive and excretory tissues, including livers > meso

17 e. microbiomes) that play important roles in digestive and immune system functioning, yet cetacean mi

18 rain, peripheral contributions involving the digestive and immune systems are emerging as factors inv

19 NIH, the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Inst

20 y the NIH/National Institute of Diabetes and Digestive and Kidney Diseases (R01 DK078192) and an NIH/

21 National Institute of Diabetes and Digestive and Kidney Diseases and National Cancer Instit

22 ed by the National Institute of Diabetes and Digestive and Kidney Diseases brought together clinician

23 2013, the National Institute of Diabetes and Digestive and Kidney Diseases convened a multidisciplina

24 ed by the National Institute of Diabetes and Digestive and Kidney Diseases focused on research gaps a

25 ed in the National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Res

26 using the National Institute of Diabetes and Digestive and Kidney Diseases harmonized protocol.

27 ng in the National Institute of Diabetes and Digestive and Kidney Diseases NASH Clinical Research Net

28 f Health, National Institute of Diabetes and Digestive and Kidney Diseases Nutrition Obesity Research

29 National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes

30 n the The National Institute of Diabetes and Digestive and Kidney Diseases Repository and included in

31 National Institute of Diabetes and Digestive and Kidney Diseases, Intercept Pharmaceuticals

32 nstitute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute on Agi

33 dney is a National Institute of Diabetes and Digestive and Kidney Diseases-led consortium to optimize

34 g Source: National Institute of Diabetes and Digestive and Kidney Diseases.

35 nd the US National Institute of Diabetes and Digestive and Kidney Diseases.

36 ) and the National Institute of Diabetes and Digestive and Kidney Diseases.

37 , and the National Institute for Diabetes on Digestive and Kidney Diseases.

38 National Institute of Diabetes and Digestive and Kidney Diseases.

39 undation, National Institute of Diabetes and Digestive and Kidney Diseases.

40 orth America; and respiratory, neurological, digestive and liver-related conditions, viral infections

41 ddition of its vascular system to documented digestive and nervous systems resolves the internal orga

42 interactions with bacteria and a variety of digestive and protective enzymes including proteases, DN

43 pathogens and encourage an appropriate milk-digestive and protective gut microbiome.

44 mic losses with each approach, but maternal, digestive, and neonatal disorders, which represent only

45 serve as a simple model of microbial-animal digestive associations, yet poorly characterized.

46 ating marine bivalve Bankia setacea, wherein digestive bacteria are housed in a location remote from

47 the amount of monosaccharides yielded by the digestive breakdown of their actual available carbohydra

48 Digestive cancer, most frequently bowel, accounted for 4

49 isk, may reduce the observed disparities for digestive cancers.

50 diet, foraging behaviour, gut morphology and digestive capabilities all work together as one nutritio

51 demands along with decreased masticatory and digestive capacities is hypothesized to have been made p

52 ter-individual phenotypic variations such as digestive capacity.

53 and was recently potentially associated with digestive carcinogenesis.

54 key body-brain connection that monitors the digestive, cardiovascular, and respiratory systems.

55 beta-lactamase-producing Enterobacteriaceae digestive colonization by weekly active surveillance cul

56 fied, 43 meat proteins were found in the two digestive compartments, 20 proteins were specific to the

57 tical component for the gut to maintain milk-digestive competence.

58 als, but it typically causes respiratory and digestive complications as well as congenital bilateral

59 and immunoreactive with simulated intestinal digestive conditions (0-60 min).

60 Digestive conditions representative of the fed state con

61 strointestinal (GI) model that simulates gut digestive conditions to study the bioaccessibility and b

62 sive literature review of the in vivo infant digestive conditions, a gastrointestinal static in vitro

63 hance the stability of LDL-based nanogels in digestive conditions.

64 ponse of intake rate not directly related to digestive constraints may determine the dynamics of inta

65 the ARCAD (Aide et Recherche en Cancerologie Digestive) database were pooled.

66 ng digestive prophylactic methods (selective digestive decontamination [SDD], acidification of gastri

67 ster-randomized crossover study of selective digestive decontamination and selective oropharyngeal de

68 Selective digestive decontamination with systemic antimicrobial th

69 s cohort of patients not receiving selective digestive decontamination/selective oropharyngeal decont

70 comparable for patients receiving selective digestive decontamination/selective oropharyngeal decont

71 enzymes show that our ape ancestors gained a digestive dehydrogenase enzyme capable of metabolizing e

72 ls that have been shown to occur in the auto-digestive disease acute pancreatitis in vivo, consistent

73 Inverse associations were also observed for digestive disease mortality for men (HR, 0.41 [CI, 0.32

74 ggest possible targets for new therapies for digestive disease states.

75 related reviews, and abstracts presented at Digestive Disease Week.

76 073), musculoskeletal diseases (38 030), and digestive diseases (27 640), and the subcategories with

77 inflammatory bowel diseases (5%), and other digestive diseases (3%).

78 es (584 days per 100 000 person years; 31%), digestive diseases (314 days; 17%), and musculoskeletal

79 ndications for HPN were divided into primary digestive diseases (PDDs) and primary nondigestive disea

80 elicobacter pylori is associated with severe digestive diseases including chronic gastritis, peptic u

81 l burden of disease due to injury, neoplasm, digestive diseases, and maternal and neonatal disorders

82 cobacter species are associated with several digestive diseases.

83 covered a novel association between COPD and digestive diseases.

84 rs, haematological malignancies, and chronic digestive diseases.

85 to external injuries, circulatory disorders, digestive disorders, and cancer (as a potential placebo)

86 ory of traditional use to treat a variety of digestive disorders.

87 nt used in traditional medicine for treating digestive disorders.

88 wn prebiotic and supports the alleviation of digestive disorders.

89 were noted in the studies (aside from minor digestive disturbance).

90 leaf antioxidants were more sensitive to the digestive environment.

91 attributed to a profound down-regulation of digestive enzyme genes and trypsin activity, upon exposu

92 n chitinase (AMCase) can function as a major digestive enzyme that constitutively degrades chitin sub

93 Pancreatic ribonuclease (RNASE1) is a digestive enzyme that has been one of the key models in

94 models appear to recover via regeneration of digestive enzyme-producing acinar cells.

95 quences are less likely to be broken down by digestive enzymes and are thus more likely to be active

96 diverse ethnicity showed similar profiles of digestive enzymes and proteins involved in translation,

97 Given the resistance of the oocyst wall to digestive enzymes and the ability of oocysts to cause pa

98 Rgs proteins inhibit the release of digestive enzymes evoked by G-protein-coupled-receptor a

99 ity of Lf is limited as it is susceptible to digestive enzymes in gastrointestinal tract.

100 Additionally, the presence of digestive enzymes positively contributed to antioxidant

101 r cell homeostasis required for secretion of digestive enzymes relies on SNARE-mediated exocytosis.

102 ioxidant capacities and abilities to inhibit digestive enzymes were characterized.

103 the chosen food samples on lipid and starch digestive enzymes were determined by evaluating the lipa

104 ion characterised by premature activation of digestive enzymes within acinar cells, followed by necro

105 h an animal gut (replete with its associated digestive enzymes) to disrupt the barrier and permit ger

106 dedicated to the production of the secretory digestive enzymes, a highly attuned surveillance of unfo

107 ciency (PEI) reduces pancreatic secretion of digestive enzymes, including lipases.

108 n wheat ATI and two representative mammalian digestive enzymes, namely trypsin and alpha-amylase.

109 adults consistently regulated genes encoding digestive enzymes, possibly to complement channel resist

110 ivo and in vitro hydrolysis by human/porcine digestive enzymes, respectively, was examined.

111 and indirectly by impairing the activity of digestive enzymes, the latter event causing the accumula

112 The exocrine compartment makes and secretes digestive enzymes, while the endocrine compartment, orga

113 f phenolic interactions with proteins and/or digestive enzymes.

114 need to produce and secrete large amounts of digestive enzymes.

115 egraded by both the Lactobacillus strain and digestive enzymes.

116 e used to investigate their capacity against digestive enzymes.

117 resulted in reduced starch susceptibility to digestive enzymes.

118 erential rates of processing by lepidopteran digestive enzymes.

119 The digestion was performed with and without digestive enzymes.

120 termediate filaments proteins of simple-type digestive epithelia and provide important cytoprotective

121 gement events that drive gut lengthening and digestive epithelial morphogenesis.

122 both formulation and processing impacted the digestive fate of the biscuits.

123 could help to understand the pathogenesis of digestive features in mastocytosis as well as in other m

124 rst analysis of a cysteine protease from the digestive fluid of a carnivorous plant and confirms the

125 In contrast, the major endopeptidases in the digestive fluid of the Venus flytrap (Dionaea muscipula)

126 mental cues, one of which is bile, a complex digestive fluid that causes potent repression of SPI-1 g

127 sit time, presence of gastric lipase, sample/digestive fluids ratio, concentration and nature of the

128 ociated DDT and chlordane by A. brasiliensis digestive fluids was reduced by at least a factor of 10

129 ant extractability by Arenicola brasiliensis digestive fluids.

130 inting workflow for human feces and in vitro digestive fluids.

131 d garlic samples as well as blood plasma and digestive fluids.

132 tly different in patients with indeterminate/digestive form of Chagas disease (35.7%) compared with t

133 Wellcome Trust, Dutch Cancer Society, Dutch Digestive Foundation.

134 nteric nervous system (ENS) is essential for digestive function and gut homeostasis.

135 -localized cysteine protease compromised VAC digestive function and markedly reduced chronic infectio

136 a noninvasive luminal pathogen that impairs digestive function in its host in part by reducing intes

137 system that simulates the main physiological digestive functions of the upper tract of healthy adult

138 ated in their common goal, which is to unite digestive functions with protection from ingested enviro

139 only are probiotics considered beneficial to digestive health, but increasing evidence suggests direc

140 newborns considering their vulnerability and digestive immaturity.

141 This could be linked to mast cell-mediated digestive inflammation among patients with mastocytosis.

142 al modes of action such as RNA interference, digestive inhibition, pathogen enhancement, antimicrobia

143 ction by the exocrine pancreas, resulting in digestive insufficiencies.

144 The most frequent adverse events were digestive intolerance in the cinacalcet group and hypoca

145 drew from the trial to address long-standing digestive issues.

146 itro cultures of A. bisporus into artificial digestive juices at 37 degrees C.

147 hydrolysis by porcine enzymes than by human digestive juices.

148 from the National Institute of Diabetes and Digestive Kidney Diseases repository and tested for seve

149 The impact of milk pasteurization digestive kinetics and disintegration was tested with th

150 as to determine the potential of immobilised digestive lipase from Chinook salmon (Oncorhynchus tshaw

151 and degradation of the payload within acidic/digestive lysosomal compartments.

152 lopment (BMP2, BMP4, GJA3, GJB2), energy and digestive metabolism (MYH, TRHDE, ALDH1A3), and nervous

153 The primary outcome was pathology-confirmed digestive necrosis.

154 telet counts (P > 0.0001) were predictive of digestive necrosis.

155 se seen in sec13(sq198), suggesting that the digestive organ defects observed in sec13(sq198) are due

156 etinal lamination, although it did result in digestive organ defects similar to those seen in sec13(s

157 The nucleolar factor, digestive organ expansion factor (DEF), has a key role i

158 in the midgut gland, which is the principle digestive organ of gastropods.

159 ne, hyperacidifying the "green stomach"-like digestive organ, whereas subsequent ones carry hydrolase

160 rafish embryos develop rapidly; all of their digestive organs are mature in larvae by 5 days of age.

161 testinal tract, but their influence on other digestive organs is less well explored.

162 e found for malignant neoplasms, diseases of digestive organs, and diseases of the circulatory system

163 tumors of the lip, oral cavity and pharynx, digestive organs, respiratory tract, female genitalia an

164 ng compensatory and physical effects on both digestive parameters.

165 complexes could be used in the prognosis of digestive pathologies of clinical forms of Chagas diseas

166 n with the humoral response in patients with digestive pathologies.

167 In vitro digestive pattern of roe powder indicated higher amount

168 d fast transit times that typify caterpillar digestive physiology may prevent microbial colonization.

169 ve control measures are underway, the unique digestive physiology of these pests presents a significa

170 By out-sourcing this aspect of digestive physiology to our gut microbes, we maximize ou

171 Understanding of N. viridula digestive physiology will facilitate the design of new s

172 ecies-even pairs of grazers matched in size, digestive physiology, and location-and dietary similarit

173 ape the microbiota because of a gap in human digestive physiology, which is equipped to assimilate on

174 d inhibitors show a similar activity against digestive Plms I, II, and IV and >10-fold selectivity ve

175 d, or complained of back pain, migraines, or digestive problems at baseline.

176 tance by limiting toxin assimilation via the digestive process.

177 ng these fishes regarding their roles in the digestive processes of hosts feeding predominantly on po

178 The pancreas secretes digestive proenzymes typically in their monomeric form.

179 patients hospitalized in ICUs and evaluating digestive prophylactic methods (selective digestive deco

180 Chitinase and digestive protease transcript expression levels correlat

181 atment of the compounds with chymotrypsin, a digestive protease, did not affect the induced B lymphoc

182 Research in insect digestive proteases has revealed the crucial roles they

183 s is associated with premature activation of digestive proteases in the pancreas.

184 tall patches are not of significantly lower digestive quality than the pasture average.

185 ethanolamine (PEA) play an important role in digestive regulation, and we hypothesized they would als

186 ) included several sites in the respiratory, digestive, reproductive, and urinary systems.

187 rgery was performed in 24 patients (20%) and digestive resection was completed in 16.

188 luding LaMer growth, aggregative growth, and digestive ripening.Synthetic nanochemistry currently lac

189 Risks of digestive, skin, and musculoskeletal complications also

190 Furthermore, MIR2911 exhibited unusual digestive stability compared with other synthetic plant

191 l in vitro starch fractions such as: rapidly digestive starch (RDS), slowly digestive starch (SDS) an

192 h as: rapidly digestive starch (RDS), slowly digestive starch (SDS) and resistant starch (RS) of nati

193 ere, we demonstrate a previously undescribed digestive strategy in the wood-eating marine bivalve Ban

194 Mastocytosis patients with digestive symptoms displayed significantly increased kyn

195 y controls and mastocytosis patients without digestive symptoms.

196 modifications, we used a dynamic artificial digestive system (DIDGI(R)) that mimics the physicochemi

197 e radial nerve cords, circumoral nerve ring, digestive system (e.g., cardiac stomach) and body wall-a

198 s such as behavioral and neurological AE and digestive system AE.

199 E1 genes from Caniformia, which has a simple digestive system and lacks microbial digestion typical o

200 esults broaden the current knowledge of tick digestive system and may lead to the discovery of potent

201 ncer, associations with other cancers of the digestive system are poorly established.

202 ion within Teredinidae, the reduction of its digestive system by comparison with other family members

203 physical activity were associated with lower digestive system cancer risk (hazard ratio [HR], 0.74 fo

204 ted the role of physical activity in overall digestive system cancer risk.

205 k, was inversely associated with the risk of digestive system cancers, particularly digestive tract c

206 exercise was particularly beneficial against digestive system cancers, with the optimal benefit obser

207 24 person-years, we documented 1370 incident digestive system cancers.

208 at common carcinogenic pathways may underlie digestive system cancers.

209 Despite descriptions of the ctenophore digestive system dating to Agassiz [16] that identify tw

210 Digestive system development is orchestrated by combinat

211 Incident cancer of the digestive system encompassing the digestive tract (mouth

212 rved gene involved in the development of the digestive system in many animals, has an important role

213 participate in the building of a functional digestive system in metazoans, and genetic conditions in

214 an-specific functions of SPs and KLFs in the digestive system including the oral cavity, esophagus, s

215 Here we investigated stem-cell death in the digestive system of adult Drosophila melanogaster.

216 f ~65 kDa, present in the body periphery and digestive system of infective larvae (L3), as demonstrat

217 assiz [16] that identify two openings of the digestive system opposite of the mouth-called "excretory

218 ented soymilk storage and after the in vitro digestive system simulation (DSS).

219 s increased significantly after the in vitro digestive system simulation of the product.

220 erlying UFP-mediated lipid metabolism in the digestive system with clinical relevance to gut homeosta

221 ood uptake after injury, degeneration of the digestive system would often occur indicating limited en

222 n radial nerve cords, circumoral nerve ring, digestive system, tube feet and innervation of interossi

223 a life-threatening disorder of the lungs and digestive system.

224 us, such as the smooth-muscle actions of the digestive system.

225 fiber that is not digested in the mammalian digestive system.

226 ses in its capacity as the first part of the digestive system.

227 eptide digestion and absorption in the human digestive system.

228 oesophagus and other narrow orifices in the digestive system.

229 oted Treg accumulation within lesions of the digestive system.

230 ate normal functions and pathobiology in the digestive system.

231 in the development of mammalian nervous and digestive systems.

232 of which 12 kg would be absorbed into mussel digestive systems.

233 opods that are involved in the protection of digestive tissues against complement system-mediated dam

234 meal requires an interplay between multiple digestive tissues, sympathetic response pathways, and th

235 non-surgically inserted into a rodent lower digestive track to improve the imaging quality of deep-l

236 ach the region of interest through the lower digestive track, similar as a colonoscopy detector.

237 on sensitivity of deep-lying organs near the digestive track.

238 n epidermis and the mucosal epithelia of the digestive tract (K14 HPV49 E6/E7-Tg mice).

239 cer of the digestive system encompassing the digestive tract (mouth, throat, esophagus, stomach, smal

240 investment in muscularity, adiposity and the digestive tract allow for a larger brain.

241 The close proximity of the pancreas to the digestive tract allows EUS to obtain detailed images of

242 ecimens of which preserve traces of muscles, digestive tract and brain.

243 er ingestion, salmonellae traverse the upper digestive tract and initiate tissue invasion of the dist

244 However, PAs are unstable in the digestive tract and must be stabilized to allow oral adm

245 e functions of each anatomical region of the digestive tract are summarized.

246 he inverse association was more evident with digestive tract cancers (HR, 0.66 for >/=63.0 vs </=8.9

247 sk of digestive system cancers, particularly digestive tract cancers, in men.

248 /E7-Tg mice were highly susceptible to upper digestive tract carcinogenesis upon initiation with 4-ni

249 Invasive infections of the CNS or digestive tract caused by Candida species in previously

250 tions of the central nervous system (CNS) or digestive tract caused by commensal fungi of the genus C

251 Ready translocation in mice after digestive tract challenge demonstrates the potential of

252 The acquisition rate of digestive tract colonization during ICU stay was 7% (95%

253 we interpret as a lophophore, and a U-shaped digestive tract ending in a dorsolateral anus.

254 thelium is generated after the epidermis and digestive tract epithelia have matured, ensuring that bo

255 Understanding the basis for digestive tract functions is essential to understand dys

256 The mucous barrier of our digestive tract is the first line of defense against pat

257 the viability of these bacteria through the digestive tract may be relevant to evaluate their potent

258 nia pestis adopts a unique life stage in the digestive tract of its flea vector, characterized by rap

259 icrobial community that resides in the upper digestive tract of ruminant animals and is responsible f

260 g, copepods passed P. bursaria through their digestive tract only partially digested, releasing endos

261 Patients who underwent upper digestive tract reconstruction for caustic injuries by c

262 anatomical asymmetry in other regions of the digestive tract remain unknown.

263 t are highly prevalent across cancers of the digestive tract showed significantly higher abundances i

264 We analyzed DNA methylation profiles of the digestive tract surface and the central bulk and invasiv

265 uitoes host communities of microbes in their digestive tract that consist primarily of bacteria.

266 stigated in an in vitro mimetic model of the digestive tract using specific chemical traps.

267 The digestive tract was divided into 4 organs and subsequent

268 After killing, all parts of the digestive tract were analysed by a pathologist unaware o

269 taken along the longitudinal axis of the rat digestive tract were subjected to 16S rRNA gene sequenci

270 ion, associated with the colonization of the digestive tract with extended-spectrum beta-lactamase-pr

271 nsiderable carbonylation was observed in the digestive tract, especially under the acidic conditions

272 When limited to digestive tract, infection may resolve without IS reduct

273 ith unexplained invasive disease of the CNS, digestive tract, or both caused by Candida species.

274 in enteroendocrine cells in the lumen of the digestive tract, these results suggest that GABA in came

275 to food and bacterial constituents from the digestive tract.

276 tors with context-dependent functions in the digestive tract.

277 compounds in conditions simulating the human digestive tract.

278 coloplasty for caustic injuries of the upper digestive tract.

279 f probiotics to promote wound healing in the digestive tract.

280 estibility and fermentation model of the pig digestive tract.

281 the risk of cancers occurring throughout the digestive tract.

282 thway that stimulates the development of the digestive tract.

283 he peritrophic/mucous membrane in the larval digestive tract.

284 ies to treat diseases of the oral mucosa and digestive tract.

285 d under simulated in-vitro conditions of the digestive tract.

286 ins within the different compartments of the digestive tract.

287 link the external epidermis to the internal digestive tract.

288 to rapidly visualise mucosal surfaces in the digestive tract.

289 Anaerobic environments such as mammalian digestive tracts and industrial reactors harbor an abund

290 In most animals, digestive tracts harbor the greatest number of bacteria

291 Anthropogenic debris was extracted from the digestive tracts of fish and whole shellfish using a 10%

292 y is associated with microbes inhabiting the digestive tracts of ruminants and other animals, feeding

293 sizes and colors were found in 27.6% of the digestive tracts of the nine dominant species regardless

294 y, unique structural aspects of invertebrate digestive tracts that contribute to symbiont specificity

295 lia of human respiratory, genitourinary, and digestive tracts.

296 ide polymorphisms in pfmdr1, which encodes a digestive vacuole membrane-bound ATP-binding cassette tr

297 ISPR-Cas9-based gene editing, identified the digestive vacuole membrane-spanning transporter PfMDR1 (

298 were identified as a novel class of malaria digestive vacuole plasmepsin inhibitors by using NMR-bas

299 -product of hemoglobin catabolism within the digestive vacuole, where heme is predominantly sequester

300 Mutations in both digestive vacuole-resident transporters are thought to d

301 ve and -resistant parasites, causes enlarged digestive vacuoles, and renders chloroquine-resistant st