ライフサイエンスコーパス: diisopropyl

1 2,9-dimethyl-1,10-phenanthroline; dipp = 2,9-diisopropyl-1,10-phenanthroline (dipp); tfpb(-) = tetrak

2 ethyl-(1-heptenyl)silanol ((E)-1) and of (E)-diisopropyl-(1-heptenyl)silanol ((E)-2) with 2-iodothiop

3 Single-crystal X-ray diffraction analysis of diisopropyl 2-iodoxyisophthalate 6b showed intramolecula

4 which are nonnucleophilic bases, 4-ethyl-2,6-diisopropyl-3,5-dimethylpyridine (4) is also such a base

5 ative aldehyde (the "monomeric" aldehyde) is diisopropyl-3-formyl-4-(2-methylprop-1-enyl)cyclopent-3-

6 -diquinolyl)naphthalene, 2, and 1,8-bis(2,2'-diisopropyl-4,4'-diquinolyl)naphthalene, 3, in 42% and 4

7 -diquinolyl)naphthalene, 8, and 1,8-bis(2,2'-diisopropyl-4,4'diquinolyl)naphthalene N,N'-dioxide, 9,

8 The N-heterocyclic carbene 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (Pr(i)2NHCMe2

9 ) = +11.8 kcal/mol is found when the NHC 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene is employed a

10 4,6-triisopropylphenyl, NHC(iPr2)(Me2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) is obtained

11 Pr(2)Me(2))(4)H](+) (1, I(i)Pr(2)Me(2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene) with oxygen

12 (Pr(i)(2)NHCMe(2) = C(11)H(20)N(2) = 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene).

13 ine-2,6-dicarboxamide, (NO2)L = N,N'-bis(2,6-diisopropyl-4-nitrophenyl)pyridine-2,6-dicarboxamide), a

14 ore in the complexes LCuOH (L = N,N'-bis(2,6-diisopropyl-4-R-phenyl)pyridine-2,6-dicarboxamide, R = H

15 es: see text] The diradical methylenebis(1,5-diisopropyl-6-oxoverdazyl) was synthesized by benzoquino

16 Diethyl (7, MRS4084) and diisopropyl (8, MRS4074) phosphotriesters were highly pr

17 '-diacridyl)naphthalene, 2, and 1,8-bis(4,4'-diisopropyl-9,9'-diacridyl)naphthalene, 3, did not show

18 tion-state structure of THF solvated lithium diisopropyl amide (LDA) in hydrocarbon solvent was chose

19 te consisting of pinacolone enolate, lithium diisopropyl amide, lithium oxide, and HMPA in the ratio

20 d for the N,N-diethyl amides 5a than the N,N-diisopropyl amides 5b.

21 h a general difunctionalization using simple diisopropyl azodicarboxylate (DIAD) as a radical trap.

22 ol in the presence of triphenylphosphine and diisopropyl azodicarboxylate (DIAD) is utilized to prepa

23 nmoser's salt, Togni's reagent, Selectfluor, diisopropyl azodicarboxylate (DIAD), MeSX) in high regio

24 riphenylphosphine (Ph(3)P) with an excess of diisopropyl azodicarboxylate at 0-25 degrees C resulted

25 fferent solvents (acetonitrile, benzene, 1,3-diisopropyl-benzene) for the charge separation and the c

26 Ortholithiation of 3-fluorophenyl-N,N-diisopropyl carbamate by lithium diisopropylamide (LDA)

27 oates (TIB esters) and secondary dialkyl N,N-diisopropyl carbamates have been reported to be resistan

28 roxy phosphonic acid mono methyl esters with diisopropyl carbodiimide at ambient temperature leads to

29 on a cyclopropyl derivative of Bingel and a diisopropyl cyclohexyl C60 alcohol (4a) as synthesized b

30 With N,N-bis(2,6-diisopropyl)dihydroimidazolium chloride (10) as the liga

31 Diisopropyl ester 16 (MRS2978) of (1'S,2'R,3'S,4'R,5'S)-

32 The dimethyl and diisopropyl esters of 2-iodoxyisophthalic acid were prep

33 Radicals derived from dioxane and diisopropyl ether by flash photolysis of DTBP in etherea

34 ther volatile anesthetics, diethyl ether and diisopropyl ether, reduce the quenching caused by haloth

35 inhibitors phenylmethylsulfonyl fluoride and diisopropyl fluoride were found to have a profound effec

36 ed by both phenylmethylsulfonyl fluoride and diisopropyl fluoride.

37 FXIa(G193E) inhibition by diisopropyl fluoro-phosphate was approximately 30-fold s

38 exclusive substrate specificities, PON1 and diisopropyl fluorophosphatase (DFPase) have essentially

39 Purified PKA was blocked by diisopropyl fluorophosphate (1 mm), phenylmethylsulfonyl

40 Diisopropyl fluorophosphate (DFP) causes neurotoxicity r

41 ates with challenging leaving groups such as diisopropyl fluorophosphate (DFP) or venomous agent X, c

42 The irreversible AChE inhibitor diisopropyl fluorophosphate (DFP) usually caused a susta

43 Diisopropyl fluorophosphate (DFP) was used as a nerve ga

44 The addition of a CE inhibitor, diisopropyl fluorophosphate (DFP), to mouse serum in vit

45 l phosphoproteins evoked by the OP compound, diisopropyl fluorophosphate (DFP).

46 of the nerve agent organophosphate substrate diisopropyl fluorophosphate (DFP).

47 erties of thrombin by hirudin and trypsin by diisopropyl fluorophosphate abolished the observed RhoA

48 4-(2-aminoethyl)benzenesulfonyl fluoride and diisopropyl fluorophosphate completely inhibited Abeta d

49 the partial inhibition of enzyme activity by diisopropyl fluorophosphate or phenylmethylsulfonyl fluo

50 The enzyme was inhibited by diisopropyl fluorophosphate, a general serine class inhi

51 All enzymes were inhibited by diisopropyl fluorophosphate, a general serine class inhi

52 Diisopropyl fluorophosphate, a transition-state analog i

53 Seprase could be affinity-labeled by [3H]diisopropyl fluorophosphate, but the proteolytically ina

54 e agents, including celecoxib, rofecoxib and diisopropyl fluorophosphate, demonstrate a distribution

55 peptides with a serine proteinase inhibitor, diisopropyl fluorophosphate, indicated that they were ac

56 factor to achieve deactivation, 5 x 10(-7) M diisopropyl fluorophosphate, or the neutrophil immobiliz

57 Diisopropyl fluorophosphate, which inhibits NTE esterase

58 y inhibited by the serine esterase inhibitor diisopropyl fluorophosphate, which specifically and stoi

59 14C-Diisopropyl fluorophosphate-radiolabeled CM from MP24.15

60 d by the classical serine protease inhibitor diisopropyl fluorophosphate.

61 ked by serine-protease inhibitors, including diisopropyl fluorophosphate.

62 roteinase domain, which was labeled by [(3)H]diisopropyl fluorophosphate.

63 nctional and bound the active-site inhibitor diisopropyl fluorophosphate.

64 pecific for thrombin (reversed with inactive diisopropyl-fluorophosphate [DFP]-thrombin) and mediated

65 The native structure and a complex with diisopropyl fluorophosphonate (DFP, a potent serine hydr

66 In contrast, the substrate specificity for diisopropyl fluorophosphonate (P-F bond) was substantial

67 ion of GlpG with 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate, both mechanism-based inhi

68 ture of the covalent adduct between GlpG and diisopropyl fluorophosphonate, which mimics the oxyanion

69 ptin, angiotensin II, bradykinin, anti-PRCP, diisopropyl-fluorophosphonate (DFP), phenylmethylsulfony

70 Sequence data and 3H-diisopropyl fluorphosphate labeling results suggest that

71 emonstrate that the conformations of the N,N-diisopropyl groups in the amide moiety of 2 have a large

72 alence (ESMV) occurs in the 1,2-diphenyl-1,2-diisopropyl hydrazine radical cation, a molecule in whic

73 nd intravenously administered technetium 99m diisopropyl-imino-diacetic acid were imaged simultaneous

74 opyl ketone > t-Bu-C( horizontal lineO)-Ph > diisopropyl ketone >> t-Bu2C horizontal lineO > ClSiMe3

75 Typical examples are di-n-propyl and diisopropyl ketones (both of which produce CH(3)CH=OCF(3

76 < trans-2,3-dipropyl approximately trans-2,3-diisopropyl < cis-hexamethylene.

77 ity measurements of acetone, eucalyptol, and diisopropyl methanephosphonate.

78 tituted PTE upon addition of two inhibitors, diisopropyl methyl phosphonate and triethyl phosphate, a

79 In the case of the PTE-diisopropyl methyl phosphonate complex, the phosphoryl o

80 or acetonitrile, dimethyl methylphosphonate, diisopropyl methyl phosphonate in positive polarity and

81 tructure of PTE complexed with the inhibitor diisopropyl methyl phosphonate, which serves as a mimic

82 Two nerve agent simulants, diisopropyl methylphosphonate (DIMP) and di-methyl methy

83 of protonation on the nerve agent simulants diisopropyl methylphosphonate (DIMP) and dimethyl methyl

84 ical warfare agent (CWA) surrogate compound, diisopropyl methylphosphonate (DIMP), demonstrated that

85 l phosphate, dimethyl methylphosphonate, and diisopropyl methylphosphonate were captured by passing a

86 Diisopropyl methylphosphonate, GB impurity, was not reco

87 eridine moiety with either N,N-dipropyl, N,N-diisopropyl, N,N-dibutyl, p-methylpiperidine, or N,N-bis

88 ution reactions of N-Boc-pyrrolidine and N,N-diisopropyl-o-ethylbenzamide were performed using these

89 tentorin (1,3,4,6,8,10,11,13-octahydroxy-2,5-diisopropyl-phenanthro[1,10,9,8,o,p,q,r,a]per ylene-7,14

90 Propofol (2,6-diisopropyl phenol), a widely used systemic anesthetic,

91 olin-2-ylidene; Py = pyridine; IPr = 1,3-bis(diisopropyl)phenylimidazol-2-ylidene; dbabh = 2,3:5,6-di

92 dbabhNO (10) (Mes = mesityl; SIPr = 1,3-bis(diisopropyl)phenylimidazolin-2-ylidene; Py = pyridine; I

93 ntly bound transition state analog inhibitor diisopropyl phosphate (DIP).

94 Diisopropyl phosphofluoridate (DFP) at high concentratio

95 ate hydrolase, with the ability to hydrolyze diisopropyl phosphofluoridate and other nerve agents.

96 methyl]-3-methylpseudouridine-3'-(methyl-N,N-diisopropyl)phosphoramidite, is reported.

97 Diisopropyl phosphorofluoridate (DFP) is an organophosph

98 Diisopropyl phosphorofluoridate (DFP) produces organopho

99 reaction of Cl2(*-) with the model compound diisopropyl phosphorothioate.

100 ompounds resulting in dimethyl, diethyl, and diisopropyl phosphoryl adducts have been monitored with

101 Starting material N-(O,O-diisopropyl phosphoryl)-trans-4-hydroxy-L-proline is con

102 t contain a new TREN-based ligand [(3,5-(2,5-diisopropyl-pyrrolyl)(2)C(6)H(3)NCH(2)CH(2))(3)N](3-) ([

103 0 laboratory steps mediate the conversion of diisopropyl squarate to (+/-)-hypnophilin (8).

104 tained even when both substrates include 2,6-diisopropyl substituents.

105 l substitutions on silicon, the dimethyl and diisopropyl, were examined.