ライフサイエンスコーパス: dilator

1 ltrinitrate (GTN, an endothelium-independent dilator).

2 ons were biopsied and dilated with a balloon dilator.

3 due to the postulated additional endothelial dilator.

4 applied only to the region specified as the dilator.

5 ese enzymes converted CO from constrictor to dilator.

6 duction and converted CO from constrictor to dilator.

7 holine (ACh) and mediated by endothelial NOS dilator.

8 il, the Graether 2000, and the Morcher pupil dilator.

9 dilated with an angioplasty balloon or with dilators.

10 e were even less potent and less efficacious dilators.

11 Vessel dilator (100 ng/kg body weight per minute) given intrave

12 Vessel dilator, a 37-amino acid peptide hormone synthesized in

13 terial infusion of the endothelium-dependent dilator acetylcholine) in healthy volunteers before and

14 administration of the endothelium-dependent dilator acetylcholine.

15 achial infusion of the endothelium-dependent dilators acetylcholine (ACh) and bradykinin (BK) and the

16 ngs in response to the endothelium-dependent dilators acetylcholine and A23187 was greater in rings i

17 bral arterioles to the endothelium-dependent dilator, acetylcholine (10 micromol/L) was blunted in Mt

18 tters and hormones with both constrictor and dilator actions during hibernation are described.

19 ea (OSA) require increased pharyngeal muscle dilator activation during wakefulness to maintain upper

20 apy may be related to increased upper airway dilator activity in sleep and/or enhanced slow-wave slee

21 triction competes with endothelium-dependent dilator activity to determine post-exercise arterial fun

22 ed sleep-related suppression of upper airway dilator activity, p < 0.02.

23 ayer, which includes a marked increase in NO dilator activity.

24 c was not mediated by changes in endothelial dilator activity.

25 response curves to different constrictor and dilator agonists were obtained at an intraluminal pressu

26 illary block was not as large as that of the dilator anatomy according to the quantified values of AO

27 l thickness iris) to quantify the effects of dilator anatomy, (2) in the presence (+PB) versus absenc

28 uction may contribute to impaired functional dilator and hyperaemic responses at the venular level.

29 the cremaster muscle (0.5, 1, 3 Hz), venular dilator and hyperaemic responses to lower frequencies we

30 STG, including the activation of the pyloric dilator and pyloric neurons, an increase in the pyloric

31 activity was present in ciliary muscle, iris dilator and sphincter muscles, and blood vessel smooth m

32 ttenuation of vasodilation to cAMP-dependent dilators and enhanced vasoconstriction to ET-1.

33 The use of different dilators and tract size continues to be examined.

34 x, the physiology of the upper airway muscle dilator, and the stability of ventilatory control are im

35 The upper airway dilators are much more susceptible to a decrease in musc

36 The pyloric dilator axons of the stomatogastric nervous system in th

37 er vaccination) to the endothelium-dependent dilator bradykinin (BK) and the endothelium-independent

38 The peptide dilators calcitonin gene-related peptide (CGRP) and vaso

39 e (NO)-mediated artery function, and conduit dilator capacity (DC), a surrogate marker for arterial r

40 e was no evidence that adenosine can release dilator concentrations of K+ from skeletal muscle fibres

41 ictor response distinct from the multiphasic dilator/constrictor response to adenosine.

42 TER FROM 3.0 TO 5.4 MM IN 10 SECONDS, ACTIVE DILATOR CONTRACTION WAS APPLIED BY IMPOSING STRESS IN TH

43 The posterior location of the dilator contributes to the anterior iris bowing via a no

44 (4 mum, 1% of full thickness) versus a thick dilator (covering the full thickness iris) to quantify t

45 Vessel dilator decreased systemic vascular resistance 24%, pulm

46 ABSTRACT: Endothelial dilator dysfunction contributes to pathological vascular

47 AJ activity can account for the endothelial dilator dysfunction in old arteries.

48 junctions, which contributes to endothelial dilator dysfunction.

49 men with higher VM/VP ratios (i.e., greater dilator effect of a DI) tended to have greater methachol

50 nteric arteries (MAs) and veins (MVs) to the dilator effect of CCBs.

51 Second, the possible dilator effect of endothelin-B receptor activation was t

52 the constrictor effects exceeds that of the dilator effects by the magnitude of the TGF response.

53 lium is involved in both the constrictor and dilator effects of endothelin in rat pulmonary artery, c

54 ute hypertension and (2) block nNOS-mediated dilator effects of N-methyl-D-aspartate (NMDA) delivered

55 Vessel dilator enhanced sodium excretion 3- to 4-fold in CHF su

56 hypoxia is attenuated and replaced by other dilator factors.

57 ng the possibility that both constrictor and dilator fibres are present.

58 Carbachol was the most efficacious dilator, followed by isoprenaline.

59 ased screening method for identifying potent dilators from among the many thousands of available bitt

60 es of pravastatin-treated monkeys had better dilator function and plaque characteristics more consist

61 The endothelial dilator function appeared normal.

62 o adrenergic agonists as well as endothelial dilator function did not differ between PS and controls.

63 dministered high-dose folic acid on coronary dilator function in humans.

64 further characterization of constrictor and dilator function in mesenteric and caudal femoral arteri

65 Endothelial-dependent dilator function was determined by the topical applicati

66 Endothelial-dependent dilator function was preserved with PR.

67 oth muscle dilation (endothelial-independent dilator function) in all groups.

68 ss, together with testing of constrictor and dilator function.

69 mia adversely effects coronary microvascular dilator function.

70 While individual vasoconstrictor and dilator genes have been identified, the coordination of

71 dykinin (BK) and the endothelium-independent dilator glyceryl-trinitrate (GTN).

72 These results indicate that vessel dilator has significant beneficial diuretic, natriuretic

73 There was a significant correlation between dilator impairment and the degree of dyslipidemia record

74 p38 MAPK inhibitor, SB203580, prevented NMDA dilator impairment significantly less than the ERK MAPK

75 es to endothelium-dependent and -independent dilators in the ovine fetal pulmonary circulation.

76 onses to ET-1 and iloprost, a cAMP-dependent dilator, in vivo, plus the effects of such treatment on

77 also suggest that adenosine had little tonic dilator influence in CH rats breathing 12% O2 despite it

78 rats were more sensitive than N rats to the dilator influence of acute systemic hypoxia and this was

79 We suggest that in CH rats, the dilator influence of adenosine in acute hypoxia occurs v

80 Exposure to ONOO(-) reduced the dilator influence of K(v) channels in RSCAs.

81 to HG for 24 h showed a loss of K(v) channel dilator influence that also was partially restored by th

82 cle vasculature are largely blunted by local dilator influences, despite high instantaneous frequenci

83 lature after hemorrhage in favor of enhanced dilator mechanisms in premucosal vessels with enhanced c

84 ion was designed to determine whether vessel dilator might have similar beneficial effects in persons

85 ctions in serotonin delivery to upper airway dilator motoneuron activity may contribute to sleep apne

86 eceptor subtypes implicated in excitation of dilator motor neurons was evaluated in anesthetized, par

87 Pharyngeal dilator muscle activation (GGEMG) during wakefulness is

88 of local mechanisms in mediating pharyngeal dilator muscle activation in normal humans during wakefu

89 small upper airway with augmented pharyngeal dilator muscle activation maintaining airway patency awa

90 ortant in mediating the increased pharyngeal dilator muscle activation seen in sleep apnea patients d

91 imulus) were important in driving pharyngeal dilator muscle activation, one would predict that during

92 ich could not be explained by differences in dilator muscle activation.

93 aoral surface electrode to record pharyngeal dilator muscle activity (the genioglossus [EMGgg] normal

94 aoral surface electrode to record pharyngeal dilator muscle activity (the genioglossus [EMGgg]), we e

95 pper airway collapse is decreased pharyngeal dilator muscle activity during sleep.

96 ep apnea (OSA) may have augmented pharyngeal dilator muscle activity during wakefulness, to compensat

97 of two serotonin antagonists on upper airway dilator muscle activity, diaphragm activity, Sao2, and u

98 With reductions in dilator muscle activity, upper airway cross-sectional ar

99 riven primarily by posterior location of the dilator muscle and by dynamic pupillary block, but the e

100 is, we assessed the relationship between two dilator muscle electromyograms (EMGs, i.e., genioglossus

101 and collapsibility and enhanced upper-airway dilator muscle responses to avoid OSA.

102 The genioglossus is an upper airway dilator muscle, the length of which is directly related

103 ugh alpha-adrenergic stimulation of the iris dilator muscle.

104 chanics, ventilation, plus activation of two dilator muscles (genioglossus [GG] and tensor palatini [

105 Pharyngeal dilator muscles are clearly important in the pathogenesi

106 Pharyngeal dilator muscles are clearly important in the pathogenesi

107 Pharyngeal dilator muscles are clearly important in the pathophysio

108 Pharyngeal dilator muscles are important in the pathophysiology of

109 Upper airway dilator muscles are phasically activated throughout brea

110 The stimuli controlling pharyngeal dilator muscles are poorly defined.

111 ay have augmented serotonergic control of UA dilator muscles as a mechanism to prevent pharyngeal col

112 ta provide strong evidence that upper airway dilator muscles can be activated throughout inspiration

113 he complex lumen and marked expansion of the dilator muscles characteristic of 50- and 100-day untrea

114 activation is similar to that of pharyngeal dilator muscles during spontaneous and induced apneas, a

115 n is in the nucleus ambiguus innervating the dilator muscles of the soft palate, pharynx, and larynx,

116 mitigated by highly responsive upper-airway dilator muscles to avoid OSA.

117 way anatomy, (2) the ability of upper airway dilator muscles to respond to rising intrapharyngeal neg

118 increased mechanoreflex-mediated activity of dilator muscles while awake, but this reflex is inhibite

119 neuropil and orthodromically to the pyloric dilator muscles.

120 lung volume, and dysfunctional upper airway dilator muscles.

121 ate block, our data suggest that sympathetic dilator nerves are not responsible for limb vasodilatati

122 d to all six modulators, but the ventricular dilator neuron only responded to a subset of them.

123 imental phase resetting curves for a pyloric dilator neuron show satisfactory agreement.

124 he pyloric (PY) neurons, and the ventricular dilator neuron.

125 xon of the crustacean stomatogastric pyloric dilator neuron.

126 , gastric mill, lateral pyloric, and pyloric dilator neurons from male crabs of the species Cancer bo

127 We studied the axons of the pyloric dilator neurons in the stomatogastric nervous system of

128 tion being mediated by sensory nerve-derived dilator neuropeptides CGRP and substance P, and also nNO

129 dykinin (BK) and the endothelium-independent dilators NTG and verapamil (resistance vessel response).

130 or pupil expansion include the Beehler pupil dilator, nylon iris hooks, and pupillary rings, includin

131 Strikingly, acetylcholine, a powerful dilator of most vascular beds, virtually lost the abilit

132 Relaxin is a powerful dilator of systemic resistance arteries secreted by the

133 , organic nitrates are established selective dilators of conduit arteries.

134 t pial arteries constricted and responses to dilator opioids were blunted after fluid percussion inju

135 , five occurred during passage of the bougie dilator or nasogastric tube, and two occurred after surg

136 e normal 1:1 alternation between the pyloric dilator (PD) and LP neurons to patterns of 2:1, 3:1, or

137 The pyloric dilator (PD) neuron exclusively expresses D2Rs.

138 roperties and synaptic output in the pyloric dilator (PD) neuron, in part by reducing calcium current

139 lateral pyloric (LP) neuron and the pyloric dilator (PD) neurons after blocking action potential-med

140 The two pyloric dilator (PD) neurons are active in the pyloric rhythm, h

141 ic circuit of the spiny lobster, the pyloric dilator (PD) neurons are members of the pacemaker group

142 ndent Ca(2+) accumulation in the two pyloric dilator (PD) neurons of the pyloric network in the spiny

143 We previously showed that, in pyloric dilator (PD) neurons of the stomatogastric ganglion (STG

144 he peripheral motor axons of the two pyloric dilator (PD) neurons of the stomatogastric ganglion in t

145 sion in the two electrically coupled pyloric dilator (PD) neurons showed significant interanimal vari

146 hereas the anterior burster (AB) and pyloric dilator (PD) neurons were rhythmically active at a low f

147 Proctolin additionally acts on the pyloric dilator (PD) neurons, the pyloric (PY) neurons, and the

148 solate the anterior burster (AB) and pyloric dilator (PD) neurons.

149 pse from the lateral pyloric (LP) to pyloric dilator (PD) neurons.

150 burst amplitude and duration in the pyloric dilator (PD) neurons.

151 cemaker neurons anterior burster and pyloric dilator (PD).

152 s: the anterior burster (AB) and the pyloric dilator (PD).

153 The single-dilator percutaneous tracheostomy technique is a safe, c

154 e (average 70%), showing that the anatomy of dilator plays an important role in iris deformation duri

155 on, and a single muscle group--the laryngeal dilators--produces underwater calls.

156 ecause of an enhanced release of endothelial dilator prostaglandins and suggest that this vascular ad

157 dulated by substances such as endothelin and dilator prostaglandins, normoxic contraction is an intri

158 dilation, suggesting that it was mediated by dilator prostaglandins.

159 omerulus may counteract the effects of these dilator prostanoids and increase glomerular resistance.

160 ty of the iris to dilate owing to absence of dilator pupillae muscle.

161 IAs in the lateral pyloric (LP) and pyloric dilator (PY) cells, and the Drosophila shal current.

162 The impaired dilator reactivity in OZR reflects a loss in venular nit

163 , both post-capillary and collecting venular dilator reactivity within the skeletal muscle of obese Z

164 ACTION WAS APPLIED BY IMPOSING STRESS IN THE DILATOR REGION.

165 Furthermore, folate increased dilator reserve by 83% in abnormal segments (0.77 +/- 0.

166 in/g, placebo vs. folate, p < 0.05), whereas dilator reserve in normal segments remained unchanged (2

167 The dilator response (P < 0.05) and sensitivity (P < 0.05) t

168 infusion also resulted in greater epicardial dilator response after ACh among African Americans.

169 have a role in temperature sensation or the dilator response in human skin.

170 spontaneous myogenic tone, but enhanced the dilator response of penetrating arterioles to extralumin

171 perfusion (7.7+/-1.5% to 3.5+/-0.9%) and the dilator response of resistance vessels to acetylcholine

172 IR did not reduce the dilator response of the radial artery to glyceryltrinitr

173 gliben-clamide-sensitive afferent arteriolar dilator response to 1 microM PCO-400 (a benzopyran K(ATP

174 In addition, women with abnormal coronary dilator response to acetylcholine had less time free fro

175 LIGRL was selectively preserved, whereas the dilator response to acetylcholine was converted to const

176 rictor response to endothelin-1 and enhanced dilator response to acetylcholine was observed in CYP2J2

177 Animal studies have demonstrated that the dilator response to exogenous nitrovasodilators is exagg

178 However, neither the dilator response to nitroglycerin (21 +/- 14% vs. 18 +/-

179 None of the therapies improved the dilator response to nitroglycerin (all P>/=0.184).

180 no correlation between the magnitude of the dilator response to nitroglycerin and acetylcholine.

181 No therapy improved the dilator response to nitroglycerin.

182 contrast, in the umbilical vascular bed, the dilator response was not only prevented but reversed to

183 red for transmission or manifestation of the dilator response.

184 ation of other ion channels in mediating the dilator response.

185 with hypoxia, due to a smaller compensatory dilator response.

186 nistic effects on epicardial coronary artery dilator responses in atherosclerotic monkeys.

187 e of tamoxifen on epicardial coronary artery dilator responses in atherosclerotic, ovariectomized mon

188 n receptor as a modulator of coronary artery dilator responses in ovariectomized, atherosclerotic mon

189 Blood pressure, and constrictor and dilator responses in the aorta and mesenteric resistance

190 ed impairment of NO and K+ channel-dependent dilator responses may be responsible for the increased r

191 Estrogens have been shown to improve dilator responses of atherosclerotic coronary arteries.

192 The dilator responses of femoral arterial rings to acetylcho

193 ponses to air in CH, but reversed or reduced dilator responses to 12% O2 in N rats (to -2.4 +/- 1.3%

194 t of chronic 17beta-estradiol replacement on dilator responses to acetylcholine and sodium nitropruss

195 Similarly, dilator responses to acidosis were reduced by nearly 60%

196 ease), brachial artery endothelium-dependent dilator responses to hyperemia by ultrasonography (as an

197 predicted by a simple sum of the individual dilator responses to hypoxia alone and normoxic exercise

198 iography was used to measure coronary artery dilator responses to intracoronary infusions of acetylch

199 Dilator responses to leucine enkephalin and dynorphin, e

200 However, whether arteriolar dilator responses to NMDA are reduced during arterial hy

201 en-dependent, cytochrome P450 (CYP)-mediated dilator responses to shear stress in arterioles of NO-de

202 They also showed similar maximum dilator responses to topical adenosine (10(-3) M); 14.1

203 constricted or dilated with ACH had similar dilator responses with BK.

204 Additionally, with the impaired dilator responses, a modest increase in adrenergic const

205 Nitric oxide (NO) and K+ channel-mediated dilator responses, elicited by acetylcholine, iloprost,

206 h superoxide dismutase restored all examined dilator responses.

207 l muscle that is associated with accentuated dilator responsiveness to acute hypoxia and dilator subs

208 PSD95 appears to function as a critical 'dilator' scaffold in cerebral arteries by increasing the

209 The possible contribution of an endothelial dilator secondary to activation of adenosine receptors o

210 This enhanced dilator sensitivity is most evident in small premucosal

211 els within the physiological range, enhances dilator sensitivity of the coronary microcirculation thr

212 nitroprusside and the endothelium-dependent dilators serotonin, A23187, and substance P were obtaine

213 e, for example by facilitating conduction of dilator signals upstream.

214 ose responses to the endothelium-independent dilator sodium nitroprusside and the endothelium-depende

215 ig, pial arteries constrict and responses to dilator stimuli, including opioids, are blunted.

216 vessels to both physical and pharmacological dilator stimuli.

217 reased, consistent with removal of a hypoxic dilator stimulus that is waning in 7CH rats.

218 dilator responsiveness to acute hypoxia and dilator substances that are NO -dependent.

219 The contribution of the nitric oxide (NO) dilator system to cutaneous endothelial dysfunction is c

220 acheostomy by either the single- or multiple-dilator technique described by Ciaglia.

221 ue in 6:01 +/- 3:03 mins and by the multiple-dilator technique in 10:01 +/- 4:26 mins (p <.0006).

222 tracheostomy was performed using the single-dilator technique in 6:01 +/- 3:03 mins and by the multi

223 l tracheostomy than for the Ciaglia multiple dilator technique, pooled risk difference 0.12 (95% CI,

224 rs and to determine the efficacy of coronary dilators to attenuate their action.

225 ckade to reduce constrictor tone and augment dilator tone.

226 provide tonic, NO-dependent cerebrovascular dilator tone.

227 c oxide, contribute to resting microvascular dilator tone.

228 t one intrinsic neuron type, the ventricular dilator (VD) neuron, a highly organized and stereotyped

229 e discharges in the motoneurons: ventricular dilator (VD), PY, and LP.

230 ts only when the proper anatomic position of dilator was used.

231 eptive reflexes to phasic activity of airway dilators, we assessed genioglossal electromyogram (GG EM

232 icromol/L papaverine, a direct smooth muscle dilator, were impaired with the HM/LF diet in wild-type