ライフサイエンスコーパス: dimerization domain

1 this motif reveal a novel and stable helical dimerization domain.

2 the basic region of the TCP DNA binding and dimerization domain.

3 n/release of the PHK catalytic domain by the dimerization domain.

4 Two, however, were found in the core of the dimerization domain.

5 terminal DNA-binding domain and a C-terminal dimerization domain.

6 ff domains at opposite ends and sides of the dimerization domain.

7 erminal DNA-binding domain and an N-terminal dimerization domain.

8 terminal helices in each monomer that form a dimerization domain.

9 hain strategy that duplicated the C-terminal dimerization domain.

10 terminal DNA-binding domain and a C-terminal dimerization domain.

11 e serine receptor without the leucine zipper dimerization domain.

12 s strikingly similar to the ALDH superfamily dimerization domain.

13 functional domain and a leucine zipper as a dimerization domain.

14 -DNA recognition is enhanced by a C-terminal dimerization domain.

15 d helix-turn-helix topology and a C-terminal dimerization domain.

16 bunit, -D148FL-YI-EAH-DGW163-, serves as the dimerization domain.

17 onfirming that the C-terminus is the primary dimerization domain.

18 tive-site cysteines with respect to the DsbC dimerization domain.

19 omplete EMAP protein separated by a putative dimerization domain.

20 a weak homodimer even in the absence of its dimerization domain.

21 unaffected by mutations in the ERK putative dimerization domain.

22 tion of a six-residue portion of the C-helix dimerization domain.

23 allel orientation mediated by the N-terminal dimerization domain.

24 tively to DNA via an attached leucine zipper dimerization domain.

25 A-binding domain of the regulator toward the dimerization domain.

26 de formation within the PKGIalpha N-terminal dimerization domain.

27 of two distinct domains: a core domain and a dimerization domain.

28 ition 20 (Cys-20) of the TCP DNA-binding and dimerization domain.

29 cluding a chimera lacking the alphaE-catenin dimerization domain.

30 s bind opposing faces of the H-NS N-terminal dimerization domain.

31 splicing activity, which required the c-jun dimerization domain.

32 the crystal structure of the Xenopus laevis dimerization domain.

33 ed a significant deletion within a predicted dimerization domain.

34 A/p50) and IkappaBalpha encompasses only the dimerization domains.

35 AK2 activity independent of their N-terminal dimerization domains.

36 ation within Cx43CT, likely corresponding to dimerization domains.

37 in the coactivator-binding region, 1 in the dimerization domain, 2 around the ligand entrance site,

38 led three structural elements: an N-terminal dimerization domain, a C-terminal helix-turn-helix DNA-b

39 binding domain with a core Rossmann fold, a dimerization domain, a middle domain, a C-terminal domai

40 sm was facilitated by the acquisition of the dimerization domain, a single step that can in principle

41 veral interaction modules that include a PB1 dimerization domain, a TRAF6 (tumor necrosis factor rece

42 mposed of three domains: a carboxyl-terminal dimerization domain; a central DNA-binding, helix-turn-h

43 Targeted alanine mutations in the dimerization domain (aa 1-27) decrease phosphatase activ

44 Instead, the retroviral dimerization domain adopts a compact architecture charac

45 Amino acid substitutions in the dimerization domain affect functional TMEM16A-CaCC chann

46 r containing an N-terminal four-helix bundle dimerization domain, against which its two PH domains pa

47 n entire catalytic domain but with an intact dimerization domain, also showed isomerase activity, alb

48 onnects the inhibitor site to the N-terminal dimerization domain, although this linker determines the

49 Conversely, when IkappaBalpha binds to the dimerization domains, amide exchange throughout the DNA-

50 on of the basic helix-loop-helix DNA binding/dimerization domain and a more C-terminal region involve

51 l-defined structural models for an authentic dimerization domain and also emphasize that many feature

52 s suggest that TrbB lacks both an N-terminal dimerization domain and an alpha-helical domain found in

53 These cysteine residues serve as a dimerization domain and bind a Zn(2+) cation in a tetrat

54 r is composed of two domains, the N-terminal dimerization domain and C-terminal DNA-binding domain, w

55 MAP65 family proteins contain an N-terminal dimerization domain and C-terminal MT interaction domain

56 chitecture that includes an extended helical dimerization domain and earmuff domains at opposite ends

57 mology region but also directly involves the dimerization domain and especially its portion containin

58 interacts with PKR through its dsRNA binding/dimerization domain and inhibits its kinase activity.

59 p100 strongly interacts with its N-terminal dimerization domain and nuclear localization sequence, t

60 ding domain lies immediately adjacent to the dimerization domain and overlaps it.

61 bundle and the beta-barrel subdomains of the dimerization domain and reduce the structural stability

62 omoted mainly by a thermosensing loop in the dimerization domain and residues in the adjacent C-termi

63 Chimeras consisting of the dimerization domain and the alpha-helical linker of the

64 ture of the Escherichia coli MutL C-terminal dimerization domain and the likelihood of its conservati

65 natively unstructured linker connecting the dimerization domain and the Sin3A interaction domain of

66 The linkers between the dimerization domain and the WH domains in Tfg1 and Tfg2

67 h other AP-2 proteins in the DNA-binding and dimerization domain and weak similarity in the N-termina

68 P-epsilon(14) contains only DNA-binding and -dimerization domains and may function as a dominant-nega

69 an N-terminal DNA-binding domain, a central dimerization domain, and a C-terminal FeoA (previously S

70 nal microtubule-binding domain, a C-terminal dimerization domain, and a centriolar localization domai

71 dimerization domain was replaced by the cFos dimerization domain, and a Tam/Squelcher mutant in which

72 he tail of Smy1-which binds Myo2-its central dimerization domain, and its kinesin-like head domain ar

73 orms of E2, E2R, contain only the C-terminal dimerization domain, and repress the normal function of

74 D4 has four predicted DNA-binding domains, a dimerization domain, and two LXXLL motifs characteristic

75 n domain from the C-terminal DNA binding and dimerization domains, and we show that the C-terminal cl

76 ried within the hydrophobic core of the RelB dimerization domain appears to influence the conformatio

77 ructural integrity and function of the novel dimerization domain are essential for PKD-mediated regul

78 entral DNA-binding domain and the C-terminal dimerization domain are intrinsically disordered.

79 MarR regulators in that its DNA-binding and dimerization domains are clustered together.

80 In the NapA structure, the core and dimerization domains are in different positions to those

81 r-helix bundle, which is the phosphorylation-dimerization domain, are important for localization.

82 ely, these data highlight roles for the Stu2 dimerization domain as a scaffold for factor binding tha

83 istinct DNA-binding domains and that lacks a dimerization domain as well as a transcriptional activat

84 te- and urea-resistant NEMO dimers through a dimerization domain at the amino terminus of NEMO that o

85 forms a flattened V shape with the RI alpha dimerization domain at the point of the V and the cAMP-b

86 binds PtdOH with its N terminus and contains dimerization domains at its C terminus.

87 C-terminal tandem helix-hairpin-helix (HhH2) dimerization domain, bind to ssDNA.

88 g the ligand-binding domains but lacking the dimerization domains, bound RANK-L with a KD of approxim

89 to gp96 is also dependent on the C-terminal dimerization domain but not the N-terminal ATP-binding p

90 tructurally similar in their DNA binding and dimerization domains but differ in their transactivation

91 an action requiring both the beta1Pix DH and dimerization domains but not beta1Pix GEF activity.

92 gene products have a common DNA binding and dimerization domain, but MEF2 transcripts are alternativ

93 the AML1 DNA-binding domain and the ETO NHR2-dimerization domain, but not the ETO NHR1 domain, are cr

94 e conclude that there is no finite M6P/IGF2R dimerization domain, but rather that interactions betwee

95 have a common amino-terminal DNA binding and dimerization domain, but the four vertebrate MEF2 gene t

96 Lipid-binding sections overlapped with the dimerization domains, but also included a phox-homology

97 tably, one such isoform, FOXP2.10+, contains dimerization domains, but no DNA-binding domain, and dis

98 e domain is connected to a central, globular dimerization domain by a long antiparallel coiled coil.

99 REL has a conserved N-terminal DNA-binding/dimerization domain called the Rel homology domain (RHD)

100 nding domains, explaining how changes in the dimerization domain can alter both kinds of DNA binding.

101 Thus, the agnoprotein dimerization domain can be targeted for the development

102 The dimerization domain can independently direct its own fol

103 e relative orientation of helices in the PHK dimerization domain can reorient, via cogwheeling (rotat

104 howed that R822P substitution in the cyclase dimerization domain causing congenital early onset blind

105 Furthermore, the dimerization domain (CC) of PML was responsible for the

106 ly reported that CCM3 contains an N-terminal dimerization domain (CCM3D) and a C-terminal focal adhes

107 s pombe contains a bZIP (DNA-binding/protein dimerization) domain characteristic of ATF/CREB proteins

108 ve disposition of the earmuff domains to the dimerization domain, characteristics of the earmuff doma

109 e domain is connected to a central, globular dimerization domain, commonly called the "hinge" domain,

110 the WDR62 C-terminal region harbors a novel dimerization domain composed of a putative loop-helix do

111 Nanog protein exists as a dimer with the dimerization domain composed of a simple repeat region i

112 The addition of a strong coiled-coil dimerization domain conferred the superior inhibition ag

113 It contains a DNA-binding domain and a dimerization domain, connected by a flexible linker regi

114 he N-terminal DNA-binding and the C-terminal dimerization domains, connected by a 75-residue linker,

115 In this study, the crystal structure of the dimerization domain, consisting of residues 270-370, is

116 phenotype was dependent on the presence of a dimerization domain contained within the CRY2-fused tran

117 The C-terminal dimerization domain contains a unique solvent accessible

118 terotypic interactions between Smc1 and Smc3 dimerization domains create stable V-shaped Smc1/Smc3 he

119 BD) and in most cases a conserved C-terminal dimerization domain (CTD).

120 We first identify a PGL dimerization domain (DD) and determine its crystal struc

121 We show that the LDB1 dimerization domain (DD) is necessary and, when fused to

122 ced by attaching a DNA binding domain to the dimerization domain derived from a site-specific transcr

123 es autophosphorylation of a histidine in the dimerization domain (DHp).

124 interdomain linker can profoundly affect the dimerization domain-DNA-binding domain interactions in A

125 , is more directly involved in the protein's dimerization domain-DNA-binding domain interactions.

126 ikely are the indirect result of the altered dimerization domain-DNA-binding domain interactions.

127 omain into close proximity to the C-terminal dimerization domain (EIC), thereby permitting in-line ph

128 DGCR8 to bind heme, it must dimerize using a dimerization domain embedded within its heme-binding dom

129 s) contains a highly conserved 27-amino-acid dimerization domain enabling the protein to form a homod

130 structure of the AChE region functions as a "dimerization domain," facilitating intracellular transpo

131 (RSV) and HIV-1 to the chemically inducible dimerization domain FK506-binding protein (FKBP) or to t

132 The HKRD is a dimerization domain for PHYB homo and heterodimerization

133 eviously reported a crystal structure of the dimerization domain from human DGCR8, which demonstrated

134 asmic domain of c-MET fused to a coiled coil dimerization domain from the nuclear pore complex.

135 rotein chimeras comprising unrelated protein dimerization domains fused to thioredoxin superfamily en

136 sequential alanine-substituted mutants of a dimerization domain-green fluorescent protein fusion sho

137 The N-terminal dimerization domain has an unusual mode of dimerization;

138 hanism of inter-receptor interaction nor the dimerization domain has yet been identified.

139 sequence contains a MADS-box DNA-binding and dimerization domain; however, it does not appear to sole

140 Our results provide a mechanism by which a dimerization domain in a bHLH factor behaves as a switch

141 yl peptide bonds found on either side of the dimerization domain in close proximity to the substrate

142 luate the secondary structure of the minimal dimerization domain in genomes isolated from Moloney mur

143 provide evidence for the presence of a novel dimerization domain in multiple plant bHLH proteins.

144 e C-terminal region of TnrA corresponds to a dimerization domain in other MerR family proteins.

145 ng (PPB) domain of cdAE1 moves away from the dimerization domain in response to increasing alkalinity

146 Likewise, the presence of the NPRA dimerization domain in RetGC1/NPRA chimera specifically

147 he identification and crystal structure of a dimerization domain in the C-terminal ectodomain of gp41

148 In subsequent mapping using hybrid dimerization domains in RetGC1/NPRA chimera, multiple Re

149 tedly, structural analysis revealed that the dimerization domains include the calmodulin-binding neck

150 was rescued by the addition of a coiled-coil dimerization domain, indicating that the parental single

151 the PI[3,4,5]P(3)-binding pocket and the PH/dimerization domain interface.

152 The RNA dimerization domain is a potential target for antiretrov

153 class, the N-terminal regulatory arm of one dimerization domain is capable of interacting with the D

154 vitro association of peptides containing the dimerization domain is consistent with a homotypic prote

155 This dimerization domain is important for channel assembly in

156 found 1) that it is a homodimer, 2) that the dimerization domain is located in the amino-terminal MSD

157 ure for which dimerization via an N-terminal dimerization domain is necessary for optimal catalytic a

158 We hypothesize that the SOX9 dimerization domain is necessary to remodel the Col2a1 c

159 Serine 146 within the dimerization domain is phosphorylated and mutation of se

160 The C-terminal dimerization domain is rich in alpha-helices and shows d

161 soluble and difficult to purify, whereas its dimerization domain is the opposite.

162 he constitutive mutations in the core of the dimerization domain lead to a weakening of the support f

163 head (nucleotide-binding domain [NBD]) and a dimerization domain linked by a 50 nm long intramolecula

164 e, two N-terminal regions interact to form a dimerization domain linking two kinase domains together.

165 within the RRM2 that removes the N-terminal dimerization domain, may produce unassembled truncated R

166 /mol for the noncovalent interaction between dimerization domain monomers.

167 ession of the sequential alanine-substituted dimerization domain mutants in type II selenodeiodinase-

168 t accounts for CD in patients harboring SOX9 dimerization domain mutations.

169 The dimerization domain (nervy homology region 2) of ETO is

170 al regions, including the two alpha-helices, dimerization domain, nuclear localization sequence, and

171 ld typical of this enzyme family but lacks a dimerization domain observed in other intradiol dioxygen

172 in conformation and in dimer geometry to the dimerization domain of a bacterial transcription factor.

173 Substitutions of Arg(838) in the dimerization domain of a human retinal membrane guanylyl

174 A-SREBP-1 consists of the dimerization domain of B-SREBP-1 and a polyglutamic acid

175 e tight Kar9 interaction with the C-terminal dimerization domain of Bim1 (EB1 orthologue).

176 lacks the C-terminal DNA binding and protein dimerization domain of c-Myc.

177 ce is structurally related to the N-terminal dimerization domain of Cdc27, demonstrating that both Cd

178 endent interaction with the bZIP DNA binding/dimerization domain of CREB.

179 pled with immune depletion assays to map the dimerization domain of D1.

180 GST pulldown assays demonstrate that the dimerization domain of DP1 interacts with all three of t

181 ucted a series of chimeras comprising of the dimerization domain of DsbC, with or without the adjacen

182 ibe the structure of the extended C-terminal dimerization domain of DSX F as determined by multidimen

183 er, we found that the C-terminal DNA binding/dimerization domain of E2 is also required for efficient

184 ucing a cysteine substitution (S260C) in the dimerization domain of EnvZc, we were able to crosslink

185 e folding energy landscape of the N-terminal dimerization domain of Escherichia coli tryptophan repre

186 he solution structure of Trim5alpha BCC, the dimerization domain of Fv1 (Fv1Ntd), and the hybrid rest

187 LI, which is an engineered derivative of the dimerization domain of GCN4, a yeast transcription facto

188 e domain (TM1), similar to the transmembrane dimerization domain of glycophorin A.

189 ucture of Hha in complex with the N-terminal dimerization domain of H-NS (H-NS(1-46)) to 3.2 A resolu

190 Hha binds the dimerization domain of H-NS and may contact DNA via posi

191 gene silencing by binding to the N-terminal dimerization domain of H-NS and modifying its selectivit

192 Hha is known to interact with the N-terminal dimerization domain of H-NS; however, the manner in whic

193 abetes-associated mutation G20R perturbs the dimerization domain of HNF-1alpha, an intertwined four-h

194 ive region occurred at the N-terminus of the dimerization domain of Ku70.

195 e show that the carboxy-terminal DNA-binding/dimerization domain of LANA provides the principal inter

196 ion A (DsbA) proteins and the amino-terminal dimerization domain of macrophage infectivity potentiato

197 ssociated with cleavage of a fragment of the dimerization domain of MgrA without change in MgrA phosp

198 ned the crystal structure of the C-terminal, dimerization domain of Mif2p.

199 re a direct physical interaction between the dimerization domain of MukB and the C-terminal domain of

200 The dimerization domain of N was mapped through studies of t

201 usion protein containing the DNA binding and dimerization domain of NFI-A and the Drosophila engraile

202 ro binding experiments show that DNA-binding/dimerization domain of NRF-1 and the N-terminal half of

203 the 106-to-131 domain, corresponding to the dimerization domain of P and the C-terminal domain of FA

204 amino acids in the N-terminal leucine zipper dimerization domain of PKG Ibeta required for its bindin

205 lacking significant sequence similarity, the dimerization domain of SARS-CoV N protein has a fold sim

206 the crystal structure of the N-terminal homo-dimerization domain of Schizosaccharomyces pombe Cdc23 (

207 An N-terminal dimerization domain of SIP sits across the saddle-shaped

208 Several mutations in the dimerization domain of SoxR disrupted intersubunit commu

209 is has identified Cys(203) in the C-terminal dimerization domain of SsrB as the redox-active residue

210 ng NLD truncation mutants indicated that the dimerization domain of the NLD is confined to the conser

211 Those studies revealed that the dimerization domain of the protein forms an amphipathic

212 is a dimeric protein and that the N-terminal dimerization domain of the protein is dispensable for re

213 effective therapeutic approaches against the dimerization domain of the protein to inhibit its critic

214 flexibility in the globular interior and/or dimerization domain of the protein, and near-UV circular

215 omain of KorA is structurally similar to the dimerization domain of the tumour suppressor p53.

216 The dimerization domain of the yeast transcription factor GC

217 ast, a chimeric Arrow protein containing the dimerization domain of Torso acted as a potent amplifier

218 First, the dimerization domain of TRF2 is required to inhibit ATM a

219 and 2 inherited two missense variants in the dimerization domain of VAC14, p.Ala582Ser and p.Ser583Le

220 on requires the carboxy-terminal DNA-binding/dimerization domain of Z and the amino-terminal DNA-bind

221 nd require the DNA-binding, transposase, and dimerization domains of Abp1 to maintain transcriptional

222 e analysis of the N-terminal DNA binding and dimerization domains of HIF-1alpha and HIF-2alpha does n

223 a would fold upon binding to the p50 and p65 dimerization domains of NF-kappaB, permitting the negati

224 ad mutations in the putative DNA-binding and dimerization domains of rv2887, a gene encoding a transc

225 o activating mutations in the DNA binding or dimerization domains of STAT3 (p.K392R, p.M394T, and p.K

226 stalks in which a portion of the tether and dimerization domains of the E. coli b subunits were repl

227 zation, a process mediated by an N-terminal "dimerization domain" of RFX5 (RFX5(N)) and a C-terminal

228 ions far from the active site with the TFIIF dimerization domain on the Pol II lobe and the winged he

229 kappaBalpha as well as IkappaBalpha bound to dimerization-domain-only constructs or full-length NFkap

230 d PI[3,4,5]P(3), and mutations targeting the dimerization domain or the PH domain's PI[3,4,5]P(3)-bin

231 Likewise, deletion of p62 N-terminal dimerization domain or the TRAF6 binding site had simila

232 ain (N-TAD) (but not the DNA binding domain, dimerization domain, or C-terminal transactivation domai

233 We find that the dimerization domain overlaps with both the DNA binding d

234 a larger construct, P3P4, which includes the dimerization domain P3.

235 The CheA dimerization domain (P3) aligns roughly antiparallel to

236 ver, nearly all activity is lost without the dimerization domain (P3).

237 4) project downward below the ring, the CheA dimerization domains (P3) link neighboring rings to form

238 ic mice also expressing RARalpha linked to a dimerization domain (p50-RARalpha model) exhibited a dou

239 dedness of a loop at the base of the helical dimerization domain plays a critical role.

240 Coiled-coil dimerization domain, present in many bacterial TCPs, pot

241 aspartate receptor, Tar, to a leucine zipper dimerization domain produces a hybrid, lzTar(C), that fo

242 P)H binding domain (residues 150-250), and a dimerization domain (residues 325-451).

243 ings identify and characterize the essential dimerization domain responsible for post-translational a

244 ATRIP coiled-coil domain with a heterologous dimerization domain restored stable binding to ATR and l

245 , RanBP9-Delta1/N60, which contains the LisH dimerization domain, retained the capacity to form self-

246 lex between Hha/YmoA and the H-NS N-terminal dimerization domain reveals that the origin of the selec

247 tations have relatively small effects on the dimerization domain's ability to bind arabinose or to di

248 The heads are followed by a coiled-coil dimerization domain (S2) and a carboxy-terminal globular

249 motions between the two myosin heads and the dimerization domain (S2) in smooth muscle myosin II dete

250 LD) and an elongated, alpha-helical scaffold/dimerization domain (SDD).

251 like domain (ULD), and a C-terminal scaffold/dimerization domain (SDD).

252 Deletion of the dimerization domain sequences from DsbA2 produced the mo

253 ormed a molecular-dynamics study of the H-NS dimerization domain, showing that the parallel complex i

254 ranscription ability of wild-type SOX9 and a dimerization domain SOX9 mutant.

255 onstituting the apical loops and part of the dimerization domain, suffice for localization.

256 he carboxyl-terminal DNA binding and protein dimerization domain suggest that looping is dependent on

257 ta identify the DNA-binding domain as an ARF dimerization domain, suggest that ARF dimers bind comple

258 ) by using the CENP-B (centromere protein-B) dimerization domain suppressed the temperature sensitivi

259 First, the Borealin dimerization domain suppresses dynamic exchange at the c

260 d characterize the essential residues in the dimerization domain that are responsible for the post-tr

261 gions of TFIIF subunits Tfg1 and Tfg2 form a dimerization domain that binds the Pol II lobe on the Rp

262 tivity, as well as conferring changes in the dimerization domain that connect functionally with remot

263 termediate scaffold domain, and a C-terminal dimerization domain that contributes to oligomerization.

264 humanized mAb directed against the HER-2/neu dimerization domain that inhibits receptor signaling.

265 chromophore, followed by a carboxy-terminal dimerization domain that often transmits the light signa

266 an be overcome by fusion of the fragments to dimerization domains that facilitate correct assembly.

267 oteins with diverse activities through their dimerization domain, the chromoshadow domain.

268 In addition to the DNA-binding and protein dimerization domain, the E proteins share two highly con

269 BP-1a and -1c have identical DNA binding and dimerization domains; thus, the failure of the more abun

270 nswered question in the SMR field is how the dimerization domain (TM4) is coupled with the substrate-

271 between residues 39 and 140 and the primary dimerization domain to a region between residues 119 and

272 Moreover, the addition of a heterologous dimerization domain to Atg1 resulted in elevated kinase

273 KA), which uses a single face on its docking/dimerization domain to interact with multiple A-kinase a

274 cleocapsid (NC) domain replaced by a foreign dimerization domain to substitute for the assembly funct

275 tein with sequence similarity in a conserved dimerization domain to the LIM-domain binding 1/Chip pro

276 Proteins that employ dimerization domains to bind cooperatively to DNA have a

277 g domain from GAC1 or fusion of heterologous dimerization domains to eIF2gamma and GLC7, respectively

278 notypes can be bypassed by fusion of ectopic dimerization domains to Mek1, suggesting that the functi

279 we introduce chemically inducible, exogenous dimerization domains to the neuroligin molecule, effecti

280 modimeric V-shaped enzyme that consists of a dimerization domain, two alpha-helical linkers, and two

281 yltransferases (O-MTases) and display a weak dimerization domain unique to MTases.

282 posed on the protein surface, connecting the dimerization domains via a few interactions.

283 intracellular signaling domain of Mpl and a dimerization domain was constitutively expressed in popu

284 and a Tam/Squelcher mutant in which the cJun dimerization domain was deleted.

285 The dimerization domain was localized to an evolutionarily c

286 ecificity of GCAP binding imparted by RetGC1 dimerization domain was not directly related to promotin

287 e created a Tam/Fos mutant in which the cJun dimerization domain was replaced by the cFos dimerizatio

288 tion homology lectin domain and a C-terminal dimerization domain, we find that the C-terminal domain

289 dimer proteins and small-molecule inducible dimerization domains, we demonstrate robust and quantita

290 we present the crystal structure of the QkI dimerization domain, which adopts a similar stacked heli

291 activity in cells; this explains why the EB1 dimerization domain, which disrupts native EB dimers, ex

292 are formed by its C-terminal domain (CTD), a dimerization domain, which was found to adopt different

293 e proline-rich linker between the ATPase and dimerization domains, which generates a large central ca

294 rotein containing two domains, an N-terminal dimerization domain with a fold not previously observed,

295 The amino-terminal region forms a tight dimerization domain with a novel structural fold that in

296 sing the hydrophobic cavity and the critical dimerization domain with an improved binding affinity ov

297 omain and the carboxy terminus consists of a dimerization domain with similarity to the SinR:SinI spo

298 the alpha-helix that connects the N-terminal dimerization domain with the C-terminal thioredoxin doma

299 GCAPs, but replacing its kinase homology and dimerization domains with those from RetGC1 restored GCA

300 A putative HOP1-dependent dimerization domain within the C terminus of Mek1 has be