ライフサイエンスコーパス: dimethylamino

1 peridyl) and (1-NMe2-2-BH2-C6H4)2 (4; NMe2 = dimethylamino).

2 ,5-tetrakis(amino)benzene compounds, bearing dimethylamino (1), piperidin-1-yl (3), or morpholin-1-yl

3 available 2-(dicyclohexylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl that has been useful in C-N

4 ew ligand, 2-(dicyclohexylphosphino)-4'-(N,N-dimethylamino)-1,1'-biphenyl, was synthesized.

5 2,4,6-Tris(dimethylamino)-1,3,5-triazine was prepared to complete t

6 e-containing inhibitors [S-(R*,R*)]-N-[4-[2-(dimethylamino)-1-(1H-imidazole-1-yl)propyl]-phenyl]2-ben

7 y with the discovery of the lead compound 3-(dimethylamino)-1-(4-hexylphenyl)propan-1-one).

8 enhancement of the dansyl fluorescence of 5-(dimethylamino)-1-(naphthalenesulfonyl)glutamylglycylargi

9 of type I IDI from crystals soaked with (N,N-dimethylamino)-1-ethyl diphosphate (NIPP), a potent tran

10 of a fluorogenic sulfonamide derivative, 5-(dimethylamino)-1-naphthalenesulfonamide (dansylamide, DN

11 = 23.680(5) A; (2) (DMAPA)PbBr4 (DMAPA = 3-(dimethylamino)-1-propylamine), which crystallizes in P21

12 )- or 2-(1'-hydroxy-4'-methylphen-2'-yl)-4,6-dimethylamino-1,3,5-triazine with ICl provides species d

13 Derivatives of isomeric 2-(hydroxytolyl)-4,6-dimethylamino-1,3,5-triazines have been synthesized in h

14 ased on the solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN) for application

15 ive displacement of the fluorescent probes 5-dimethylamino-1-naphthalenesulfonamide and dansyl-l-prol

16 (R)-4-(3-Dimethylamino-1-phenylsulfanylmethyl-propylamino)-N-{4-[

17 Forosamine (4-dimethylamino)-2,3,4,6-tetradeoxy-beta-D-threo-hexopyran

18 new environment-sensitive fluorophore, 6-N,N-dimethylamino-2,3-naphthalimide (6DMN).

19 ,N-dimethylaminophthalimidoalanine and 6-N,N-dimethylamino-2,3-naphthalimidoalanine amino acids.

20 new series of novel P450 substrates using 6-dimethylamino-2-naphthaldehyde (6-DMANA), which has a gr

21 D-Desosamine, or 3-(dimethylamino)-3,4,6-trideoxyglucose, is an unusual suga

22 D-desosamine (1) is a 3-(N,N-dimethylamino)-3,4,6-trideoxyhexose found in a number of

23 Desosamine is a 3-(dimethylamino)-3,4,6-trideoxyhexose found in some macrol

24 Desosamine is a 3-(dimethylamino)-3,4,6-trideoxyhexose found, for example,

25 methyl-3-pyridinol (1b), and 2,4-dimethyl-6-(dimethylamino)-3-pyridinol (1d) were thus prepared from

26 e-2-ylidene; (R = 4-H, 1; 4-tert-butyl, 2; 4-dimethylamino, 3; 5-dimethylamino, 4); L = SMe(2), b; di

27 A structurally similar analog, 1-(2-dimethylamino-3-methyl-butyryl)-azetidine-2-carbonitrile

28 ubstitution from azido (3a) to amino (3b) to dimethylamino (3c) groups.

29 ompared to those of DMABN and 2-cyano-7-(N,N-dimethylamino)-4,5,9,10-tetrahydropyrene, and we show th

30 caspase-based HTS assay, 2-amino-3-cyano-7-(dimethylamino)-4-(3-methoxy-4,5-methylenedioxyphenyl)-4

31 no)-4H-chrom ene (1c) and 2-amino-3-cyano-7-(dimethylamino)-4-(5-methyl-3-pyridyl)-4H-chromene (4e),

32 H, 1; 4-tert-butyl, 2; 4-dimethylamino, 3; 5-dimethylamino, 4); L = SMe(2), b; dimethyl sulfoxide (DM

33 ctivity was inhibited by the CK2 inhibitor 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole DMAT w

34 Inhibition of CK2 kinase by 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole result

35 s (4,5,6,7-tetrabromo-1H-benzotriazole and 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole) and g

36 (i.e. 4,5,6,7-tetrabromo-1H-benzimidazole, 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole, tetra

37 o-4-(3-bromo-4,5-dimethoxyphenyl)-3-cyano-7-(dimethylamino)-4H-chrom ene (1c) and 2-amino-3-cyano-7-(

38 The 2-amino-4-aryl-3-cyano-7-(dimethylamino)-4H-chromenes also were found to be highly

39 unreacted starting material or with added 3-(dimethylamino)-5,5-dimethyl-2-cyclohexen-1-one.

40 N-Ac-Trp, indole, N-Ac-Gly, fluorescein, 1-(dimethylamino)-5-naphthalenesulfonate, and pyrene bound

41 (caging group) for carboxylic acids, the 2-(dimethylamino)-5-nitrophenyl (DANP) group, is described.

42 generated by covalently attaching a single 2-dimethylamino-6-acyl-naphthalene group to the N-terminal

43 inhibitors indolopyridone-1 (INDOPY-1) and 4-dimethylamino-6-vinylpyrimidine-1 (DAVP-1).

44 ne (7,8-DHF) and its synthetic derivative 4'-dimethylamino-7,8- dihydroxyflavone (4'-DMA-7,8-DHF) to

45 N-(6-oxo-5,6-dihydrophenanthridin-2-yl)(N,N-dimethylamino)acetamide hydrochloride (PJ34), using virt

46 nium diiodide), and acridine orange (3,6-bis(dimethylamino)acridinium chloride), as well as 140 copie

47 ectivity in comparison to ARs; related 6-N,N-dimethylamino analogue 30 was 5HT2R-selective.

48 placing desosamine with varied synthetic N,N-dimethylamino anchoring groups.

49 cell growth and tubulin polymerization, the dimethylamino and bromo cis-stilbenes were the most pote

50 ologically and pharmaceutically important o-(dimethylamino)aryl ketones, acridones, acridinium salts,

51 In contrast, the dimethylamino-aza-BODIPY derivative, 3c, showed negligib

52 the quencher nucleosides possessing 6-{4-[(4-dimethylamino)azo]phenyl}pyrrolocytosine (DABCYLpC) and

53 The method is based on detection of the 4-(dimethylamino)azobenzene-4'-sulfonyl derivative of l-met

54 gy transfer, using lipid II analogues with a dimethylamino-azobenzenesulfonyl quencher in the lipid c

55 rifluoromethyl)benzene, 4-methoxybenzene, 4-(dimethylamino)benzene, 4-(methylthio)benzene), di- and t

56 or systems were camphorquinone (CQ)/ethyl 4-(dimethylamino)benzoate (EDMAB) with or without [3-(3, 4-

57 novel self-cure system mediated by ethyl 4-(dimethylamino)-benzoate (4E) and hydroxyapatite (HAp).

58 D(4), D(6), and D(10)) deuterium enriched 4-(dimethylamino)benzoic acid (DMABA) N-hydroxysuccinimide

59 4-(Dimethylamino)benzoic acid, 1-naphthylacetic acid, and 9

60 gue of the widely studied chromophore 4-(N,N-dimethylamino)benzonitrile (DMABN).

61 l)-N-hydroxybenzamide (3c) and (E)-4-((2-(4-(dimethylamino)benzoyl)-2-methylhydrazono)methyl)-N-hydro

62 ition, the effect of compounds (E)-4-((2-(4-(dimethylamino)benzoyl)hydrazono)methyl)-N-hydroxybenzami

63 Notably, the 3,5-bis(N,N-dimethylamino)benzyl cation is predicted to have a tripl

64 nylcarbamoyl)acrylic acid (3) and (E)-N'-(4-(dimethylamino)benzylidene) diazenecarboximidhydrazide (5

65 The antiangiogenic drugs included (Z)-3-[4-(dimethylamino)benzylidenyl]indolin-2-one (a platelet-der

66 The new p-dimethylamino biphenyl ligand bears electronic similarit

67 ve probed the structures of the isomeric N,N-dimethylamino biphenyl ligands by X-ray crystallographic

68 ene)Cl2 with 2-dicyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl as the ligand, both electron-rich

69 utational study investigating substituted 2-(dimethylamino)biphenyl-2'-carboxaldehydes as substrates

70 izes gas-phase ion/molecule reactions of tri(dimethylamino)borane (TDMAB), which rapidly derivatizes

71 resent study, ion-molecule reactions of tris(dimethylamino)borane followed by collisionally activated

72 eries of mono- or bis(boryl) alkynes bis{bis(dimethylamino)boryl}ethyne, 1-phenyl-2-bis(dimethylamino

73 mation of a sterically unprotected terminal (dimethylamino)borylene complex that has a short metal-bo

74 mino)borylethyne, and 1-trimethylsilyl-2-bis(dimethylamino)borylethyne led to the isolation of hither

75 s(dimethylamino)boryl}ethyne, 1-phenyl-2-bis(dimethylamino)borylethyne, and 1-trimethylsilyl-2-bis(di

76 series of novel heterocyclic analogues of 3-(dimethylamino)butyl dimethylcarbamate (DMABC, 4).

77 ortho-Fries rearrangement and gave 6,6'-bis((dimethylamino)carbonyl)-7,7'-dihydroxy-8,8'-biquinolyl (

78 7,7'-Bis(((dimethylamino)carbonyl)oxy)-8,8'-biquinolyl (5) was prep

79 tetramethyl-1,2-ethylenediamine with 3,6-bis(dimethylamino) chalcogenoxanthones to give S- and Se-con

80 For the first time, 10-dimethylamino derivatives of benzo[h]quinoline 6 and ben

81 -methyl-N-4-carboxyphenylamino)phenyl]1-(N,N-dimethylamino) diazen-1-ium-1,2-diolate (PABA/NO) result

82 -[4-(N-methylamino)benzoyloxy]phenyl} 1-(N,N-dimethylamino)diazen-1-ium-1,2- diolate (PABA/NO) were s

83 methyl-N-4-carboxyphenylamino) phenyl] 1-N,N-dimethylamino)diazen-1-ium-1,2-diolate (PABA/NO), which

84 An electron enriched 2,4-(dimethylamino)diketiminato backbone is described, which

85 We show that N,N-(dimethylamino)dimethylchlorosilane (DMAS-Cl) reacts at t

86 tsi) (7a), Ga(Me(2)Ntsi) (7b); Me(2)Ntsi = [(dimethylamino)dimethylsilyl]bis(trimethylsilyl)methyl) m

87 r chloro (CHQ) or exchanging the hydroxy for dimethylamino (DMAQ and DMAQ-Cl) or sulfhydryl (TQ) sign

88 relies on the derivatization reaction of 2-(dimethylamino)ethanethiol (DMAET), 2-(diethylamino)ethan

89 2-(Diethylamino)ethanethiol (DEAET) and 2-(dimethylamino)ethanethiol (DMAET), the thiol-containing

90 ectron-rich alkenes, exemplified by tetrakis(dimethylamino)ethene, TDAE, and on additional driving fo

91 yl)triethylammonium bromide (QX-314), and 2-(dimethylamino)ethyl 4-(butylamino)benzoate (tetracaine),

92 proportionation of CuBr/Me6TREN (TREN = tris(dimethylamino)ethyl amine to Cu(0) powder and CuBr2 in w

93 st effective compounds in the series, 2-(N,N-dimethylamino)ethyl isothiocyanate, selectively reacts w

94 agarose and a copolymer of acrylamide and 2-(dimethylamino)ethyl methacrylate (DMAEM) cross-linked wi

95 er brushes, consisting of dual-responsive 2-(dimethylamino)ethyl methacrylate (DMAEMA) and light-sens

96 linker, and 1-allylpiperazine (1-ALPP) or 2-(dimethylamino)ethyl methacrylate (DMAEMA), in combinatio

97 from solution using poly(butadiene-block-2-(dimethylamino)ethyl methacrylate) (PB-b-PDMAEMA) diblock

98 polymer micelles comprising cationic poly(2-(dimethylamino)ethyl methacrylate) (PDMA) coronas and hyd

99 lamide) (PNIPAM) and pH responsive poly(N,N-(dimethylamino)ethyl methacrylate) (PDMAEMA) and their co

100 polyzwitterion brushes derived from poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) in water vap

101 Poly(isoprene-block-styrene-block-(N,N-dimethylamino)ethyl methacrylate) is synthesized and use

102 [2-(dimethylamino)ethyl methacrylate] (DMAEMA) was homopolym

103 Cationic poly[2-(dimethylamino)ethyl methacrylate] and anionic poly(acryl

104 )](6)](9+) (n = 0, 1, 2; Me(6)tren = tris(2-(dimethylamino)ethyl)amine), were synthesized to permit c

105 enyl]pyrimidine (1a) and amide 4,6-bis(4[(2-(dimethylamino)ethyl)carboxamido]phenyl)pyrimidine (2a) c

106 N-[2-(Dimethylamino)ethyl]-2-[4-(4-methylpiperazino)phenyl]qui

107 gues derived from the anticancer agent N-[2-(dimethylamino)ethyl]-9-aminoacridine-4-carboxamide (AAC)

108 A antagonist, SB-699551 (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methy

109 n of suitable Cu complexing ligands {tris[2-(dimethylamino)ethyl]amine (Me6TREN) and tris[(2-pyridyl)

110 ethoxygeldanamycin, and 17-demethoxy-17-[[2-(dimethylamino)ethyl]amino]-geldanamycin.

111 topoisomerase II inhibitor AQ4 [1,4-bis{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-anthracene-9,10

112 based on the parent thioether 4,6-bis[4-[[2-(dimethylamino)ethyl]mercapto]phenyl]pyrimidine (1a) and

113 3] (M = Li, Na, K), characterized as tris{2-(dimethylamino)ethyl}amine (L) complexes [(L)M][HBPh3], a

114 hite light: (1) alpha-(DMEN)PbBr4 (DMEN = 2-(dimethylamino)ethylamine), which adopts a unique corruga

115 ntraperitoneally with an hsp90 inhibitor, 17-dimethylamino-ethylamino-17-demethoxygeldanamycin (17-DM

116 edioxythiophene) (PEDOT) treated by tetrakis(dimethylamino)ethylene (TDAE) have large n-type voltages

117 ation reagent derived from CF3I and tetrakis(dimethylamino)ethylene (TDAE) was found to be effective

118 ed by mixing C2F5I and n-C4F9I with tetrakis(dimethylamino)ethylene (TDAE) were effective in their nu

119 In this work, we utilized a 7-dimethylamino flavylium heterocycle to construct a panel

120 e dismutase, or NOX4 inhibitors fulvene-5, 6-dimethylamino-fulvene, and proton sponge blue.

121 of a salt bridge between the desosamine N,N-dimethylamino functionality of the natural substrate YC-

122 exposure to HCl vapor, which protonates the dimethylamino group and inhibits the electron-donating p

123 specific interactions between the protonated dimethylamino group and the acidic amino acid residues A

124 These advanced lead compounds possess a dimethylamino group at the 6 position.

125 uted with an electron withdrawing protonated dimethylamino group at the para position, hydrogen coord

126 subunit, (2) either an N-methylamino or N,N-dimethylamino group attached in a para orientation relat

127 A m-dimethylamino group is crucial to achieve high photochem

128 the more-hindered DA product 8 (ortho to the dimethylamino group) over the less-hindered product 9 (p

129 ver the less-hindered product 9 (para to the dimethylamino group), despite the higher energy TS for 8

130 ogen-bonding network with the deoxysugar C3' dimethylamino group.

131 nvolving replacement of the C8 methyl with a dimethylamino group.

132 ylidene ligand IPr((NMe2)2) incorporates two dimethylamino groups as backbone substituents enhancing

133 The number of amino-, methylamino-, and dimethylamino groups has a significant effect on these p

134 ve site metal via its hydrazide carbonyl and dimethylamino groups.

135 ketones, acetals, ethers, silyl ethers, and dimethylamino groups.

136 ar levels are controlled by dimethylarginine dimethylamino-hydrolase (DDAH).

137 Dimethylarginine-dimethylamino-hydrolase protein expression was reduced a

138 reakdown (decreased hepatic dimethylarginine-dimethylamino-hydrolase) and/or increased production.

139 goes hepatic metabolism via dimethylarginine-dimethylamino-hydrolase, and is derived by the action of

140 hyl)carbene]pentacarbonylchromium (3a), and [dimethylamino(iso-propyl)carbene]pentacarbonylchromium (

141 Sequential formation of dimethylamino isocyanate (Me2N-NCO), 1,1-dimethyldiazene

142 and UV excitation energies of the transient dimethylamino isocyanate and 1,1-dimethyldiazene have be

143 igand bears electronic similarities to the o-dimethylamino isomer, but it also possesses structural s

144 yl)cyclopent-2-ene-1-ylidene]chromi um (5), [dimethylamino(methyl)carbene]pentacarbonylchromium (3a),

145 s (24-56 y old) using (123)I-labeled 2-((2-((dimethylamino)methyl) phenyl)thio)-5-iodophenylamine (AD

146 y reported compounds of this series, 2-(2'-((dimethylamino)methyl)-4'-(2-(18)F-fluoroethoxy)phenylthi

147 hoxy)phenylthiol)benzenamine (1) and 2-(2'-((dimethylamino)methyl)-4'-(3-(18)F-fluoropropoxy)phenylth

148 2-(2'-((Dimethylamino)methyl)-4'-(4-(18)F-fluorobutoxy)phenylthi

149 toxy)phenylthiol)benzenamine (3) and 2-(2'-((dimethylamino)methyl)-4'-(5-(18)F-fluoropentoxy)phenylth

150 the 4'-position on phenyl ring B of 2-(2'-((dimethylamino)methyl)-4'-(fluoroalkoxy)phenylthio)benzen

151 2-((2-((Dimethylamino)methyl)phenyl)thio)-5-(123)I-iodophenylami

152 The DoL of 2-[(dimethylamino)methyl]naphthalene (dman) that proceeds wi

153 (E = Ga; 79%) (Mamx = 2,4-di-tert-butyl-6-[(dimethylamino)methyl]phenyl) reacted with dilithioferroc

154 eceptor parameters with (11)C-3-amino-4-(2-[(dimethylamino)methyl]phenylthio)benzonitrile ((11)C-DASB

155 nd, N-(3-chloro-4-methylphenyl)-N'-[2-[([5-[(dimethylamino)-methyl]-2-furyl]-m ethyl)-sulfanyl]ethyl]

156 tor N-(3-chloro-4-methylphenyl)-N'-{2-[({5-[(dimethylamino)-methyl]-2-furyl}-methyl)- sulfanyl]ethyl}

157 The protein kinase C inhibitor 2-{8-[(dimethylamino)-methyl]-6,7,8,9-tetrahydropyrido[1,2-a]in

158 ring a methoxy, methylsulfanyl, methylamino, dimethylamino, methyl, or oxo group at position 6, or 2,

159 ased electron density in the vicinity of the dimethylamino moiety, for example induced by hydroxylati

160 yanthracene-9,10-dion e], a prodrug with two dimethylamino N-oxide groups, is converted to the topois

161 Mn(I) tricarbonyl complex with the ligand 5-(dimethylamino)-N, N-bis(pyridin-2-ylmethyl) naphthalene-

162 mes greater than that determined for (E)-4'-(dimethylamino)-N-methyl-4-stilbazolium hexafluorophospha

163 e technologically important material (E)-4'-(dimethylamino)-N-methyl-4-stilbazolium tosylate; (ii) re

164 han that of the commercial chromophore E-4'-(dimethylamino)-N-methyl-4-stilbazolium.

165 AQ4N [1,4-bis{[2-(dimethylamino-N-oxide)ethyl]amino}-5,8-dihydroxyanthrace

166 crystallographic model of 1,1-dicyano-2-[6-(dimethylamino)naphthalen-2-yl]propene (DDNP) bound to an

167 a-e as mixed analogues of archetypal 1,8-bis(dimethylamino)naphthalene ("proton sponge") 1 and quino[

168 1,8-Bis(dimethylamino)naphthalene ("Proton Sponge") and bromomal

169 yl- and 2,7-dialkynyl derivatives of 1,8-bis(dimethylamino)naphthalene ("proton sponge") have been ob

170 3A4(C58,C64) labeled with 6-(bromoacetyl)-2-(dimethylamino)naphthalene (BADAN), 7-(diethylamino)-3-(4

171 tive of the superbasic proton sponge 1,8-bis(dimethylamino)naphthalene (DMAN) and covalently linked i

172 P), 3-hydroxypicolinic acid (3-HPA), 1,8-bis(dimethylamino)naphthalene (DMAN), 1,8,9-anthracentriol (

173 The strong non-nucleophilic base bis(dimethylamino)naphthalene (Proton Sponge, PS) has been f

174 d full-length utrophin on 6-propionyl-2-(N,N-dimethylamino)naphthalene actin depolymerization.

175 This labeled version of CheY has the (dimethylamino)naphthalene fluorophore from Badan [6-brom

176 The fluorescent amino acid 2-amino-3-(5-(dimethylamino)naphthalene-1-sulfonamide)propanoic acid (

177 ies 20 kcal mol(-1) greater than that of bis(dimethylamino)naphthalene.

178 ene fluorophore from Badan [6-bromoacetyl-2-(dimethylamino)naphthalene] attached to the thiol group o

179 quently labeled with the N-cyclohexyl-N'-(4-(dimethylamino)naphthyl)carbodiimide (NCD-4) fluorophore,

180 y at room temperature, generating 3-(4,5-bis(dimethylamino)napthalen-1-yl)furan-2,5-dione (4-maleican

181 benzyl (Bz); pyridyl (Py); imidazolyl (Im); dimethylamino (NMe(2)); (tert-butylphenyl)pyridyl (TBP);

182 ) = 50 nM) and 21 (EC(50) = 90 nM) bearing a dimethylamino or piperidinyl group, respectively, at pos

183 e remaining PMO analogues having morpholino, dimethylamino, or N-methylamino phosphorodiamidate linka

184 oligonucleotides modified with 2'-O-[2-[(N,N-dimethylamino)oxy] ethyl] (2'-O-DMAOE) are described.

185 These studies identified an analog, dimethylamino-parthenolide (DMAPT), which induces rapid

186 We also identified 5-chloro-N-(4-(dimethylamino)phenethyl)-3-hexyl-1H-indole-2-carboxamide

187 bust CB1 allosteric modulator 5-chloro-N-(4-(dimethylamino)phenethyl)-3-pentyl-1H-indole-2-carboxamid

188 tent CB1 allosteric modulator 5-chloro-N-(4-(dimethylamino)phenethyl)-3-propyl-1H-indole-2-carboxamid

189 n of ML to its structural moieties (i.e., 4-(dimethylamino)phenol (DAP) and (8-aminoquinolin-2-yl)met

190 descending rank order for cytotoxicity was 3-dimethylamino-phenol > 2,2,6,6-tetramethyl-4-piperidone

191 dition products, two of which (involving the dimethylamino phenyl unit) are shown to form in a nonsta

192 istical dynamics in the cyclization onto the dimethylamino phenyl unit, though.

193 properties of dipolar chromophores having 4-(dimethylamino)phenyl electron donor (D) and pyridinium a

194 The cycloadducts with a 4-(dimethylamino)phenyl group on the maleimide nitrogen ato

195 The 3-(dimethylamino)phenyl groups at the alpha position prove

196 -neutral phenyl groups, electron-rich 4-(N,N-dimethylamino)phenyl substituents, and electron-poor pyr

197 -butyl, isobutyl, phenyl, 4-methylphenyl, 4-(dimethylamino)phenyl) to yield the corresponding amines

198 The fluorescent substrate 4-(4-(dimethylamino)phenyl)-1-methylpyridinium (APP(+)) exhibi

199 ide uses a fluorescein isothiocyanate/4-((4-(dimethylamino)phenyl)azo) benzoic acid (FITC/DABCYL) FRE

200 N,N'-((4-(Dimethylamino)phenyl)methylene)bis(2-phenylacetamide) wa

201 the other hand, with a 2-methoxyphenyl, a 2-(dimethylamino)phenyl, or a 3-methoxypropyl substituent,

202 oid receptor (GR) antagonist (11, 17)-11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,

203 ogical blockade of PRs by RU-486 [11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

204 e effects was inhibited by RU486 (11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

205 r antagonist RU486 [mifepristone (11beta-[p-(dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

206 lation was inhibited using RU486 (11beta-[p-(Dimethylamino)phenyl]-17beta-hydroxy-17-(1-propynyl)estr

207 Using this strategy, two compounds 2-[4-(dimethylamino)phenyl]imidazo[1,2-a]pyridine-8-ol (1) and

208 6-heptatrienal (AR-3) and 3,7-dimethyl-9-(4'-dimethylamino-phenyl)-2,4,6,8-nonatetraenal (AR-4), and

209 and two new retinal analogs, 3-methyl-7-(4'-dimethylamino-phenyl)-2,4,6-heptatrienal (AR-3) and 3,7-

210 One compound, (Z)-3-(4-dimethylamino-phenyl)-2-phenyl-acrylonitrile, was used f

211 (123)I-IMPY (6-iodo-2-(4'-dimethylamino-)phenyl-imidazo[1,2-a]pyridine) is a novel

212 0 of cTnI and the nonfluorescent acceptor 4-(dimethylamino)phenylazophenyl-4'-maleimide (DABM) attach

213 various numbers of electron-donating 4-(N,N-dimethylamino)phenylethynyl (1-4) or electron-withdrawin

214 6-Thiolato-substituted 2-(4'- N,N-dimethylamino)phenylimidazo[1,2- a]pyridines ( RS-IMPYs;

215 aluated (18)F-labeled IMPY [6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine] derivatives

216 The diol was reacted with tris(dimethylamino)phosphane and consecutively with H2(17)O t

217 mantylammonium fluoride (TMAAF), and hexakis(dimethylamino)phosphazenium fluoride (HDMAPF).

218 Only basic phosphines, such as tris(dimethylamino)phosphine, allow for the synthesis of a st

219 on led to the identification of 1,1'-bis[bis(dimethylamino)phosphino]ferrocene "DMAPF", a readily ava

220 le reaction with 1H-benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (BOP) and

221 ides and ureas with benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate (BOP), bas

222 nucleosides and 1H-benzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphate (BOP).

223 t has been found that 1,4-butanediylbis[tris(dimethylamino)]phosphonium dication is a very efficient

224 ive fluorescent amino acids derived from the dimethylamino-phthalimide family.

225 ly efficacious PI3K/mTOR inhibitor 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-

226 Additionally the N,N-dimethylamino PMO-DNA chimeras were found to stimulate R

227 nd, N-(4-(3-bromoanilino)quinazolin-6-yl)-3-(dimethylamino)propanamide (5), did not show covalent bin

228 identified two compounds, AT791 {3-[4-(6-(3-(dimethylamino)propoxy)benzo[d]oxazol-2-yl)phenoxy]-N,N-d

229 le myofibrils cross-linked with 1-ethyl-3-[3(dimethylamino) propyl] carbodiimide to prevent shortenin

230 n-based ligand that contains a hemilabile 3-(dimethylamino)propyl substituent.

231 (+/-)-Citalopram (1, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisob

232 ary development of our lead 2-cyano-3-(1-(3-(dimethylamino)propyl)-2-methyl-1H-indol-3-yl)-N-octylacr

233 pCB-coated surface via simple 1-ethyl-3-(3-(dimethylamino)propyl)-carbodiimide and N-hydroxysuccinim

234 h the carboxylic acid activator 1-ethyl-3-(3-dimethylamino)propyl)carbodiimide (EDC) and the catalyst

235 ailable peptide coupling agent 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide (EDC).

236 le cross-linking protocol with 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide (EDC).

237 1,3-indandione-1-hydrazone and 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide.

238 ite electrode (PGE) by coupling agents of N-(dimethylamino)propyl-N'-ethylcarbodiimide hydrochloride

239 nonselective PKC inhibitor Go6983 (3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-ind

240 ining molecules on tissue with 1-ethyl-3-[3-(dimethylamino)propyl]-carbodiimide hydrochloride and (ii

241 asic than parental superbase N,N',N"-tris[(3-dimethylamino)propyl]-guanidine (tris-DMPG), whereas est

242 [Cu(I)(MeAN)](+) (MeAN = N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) leads to a low-temperature s

243 ](2+) ((S)P(MeAN), MeAN: N-methyl-N,N-bis[3-(dimethylamino)propyl]amine) that featured an elongated O

244 h the zero-length cross-linker 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC) and analyzed by

245 1-Ethyl 3-[3-(dimethylamino)propyl]carbodiimide (EDC) was found to pro

246 s, a zero-length cross-linker, 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide (EDC), and the Paracoc

247 ne side chain of lisinopril by 1-ethyl-3-[3-(dimethylamino)propyl]carbodiimide hydrochloride/N-hydrox

248 N-octylacrylamide (2) confirmed the tertiary dimethylamino-propyl moiety as critical for inhibition o

249 e identification of compound OL-1 (2-(11-(3-(dimethylamino)propylidene)-6,11- dihydrodibenzo[b,e]oxep

250 itive poly(N-isopropylacrylamide)-co-(3-(N,N-dimethylamino)propylmethacrylamide) microgel (poly(NIPAM

251 pyridine] has been prepared from 3-lithio-4-(dimethylamino)pyridine (5) and triphenylacetaldehyde (3)

252 Acyl pyridinium salts derived from 4-(dimethylamino)pyridine (DMAP) and benzoic anhydride are

253 4-(N,N-Dimethylamino)pyridine (DMAP) and benzyltrimethylammoniu

254 iting diverse reactivity with phosphines, 4-(dimethylamino)pyridine (dmap) and chlorophosphines, prov

255 he complex 8 of isopinocampheylborane and p-(dimethylamino)pyridine (DMAP) can be obtained with >99%

256 d)(PPh(3))(2) (nbd = 2,5-norbornadiene)/N,N-(dimethylamino)pyridine (DMAP) catalyzed polymerization o

257 ssisted heating and a catalytic amount of 4-(dimethylamino)pyridine (DMAP) further improved the yield

258 oup on each blade of the triptycene and a 4-(dimethylamino)pyridine (DMAP) unit to selectively delive

259 nion binding catalyst in combination with 4-(dimethylamino)pyridine (DMAP), both employed at a 5 mol

260 rmaceuticals, reacts with model substrate 2-(dimethylamino)pyridine (py-NMe2; py = 2-pyridyl) to give

261 nor ligands (1-methylimidazole [MIM], 4-(N,N-dimethylamino)pyridine [DMAP], pyridine, and 1-octylimid

262 ting the kinetics of the reaction between 4-(dimethylamino)pyridine and DCM.

263 rough the interplay of benzoic anhydride, 4-(dimethylamino)pyridine as a nucleophilic catalyst, and a

264 The cation forms a Lewis adduct with 4-(N,N-dimethylamino)pyridine but a frustrated Lewis pair (FLP)

265 ional and the experimental data for the N,N-(dimethylamino)pyridine compound demonstrate nearly isoen

266 anhydride with butanol using the catalyst 4-(dimethylamino)pyridine in a microscale batch reactor.

267 A N,N-(dimethylamino)pyridine monomer is incorporated into the

268 nd (3) either an N-methylaniline or a 2-(N,N-dimethylamino)pyridine ring.

269 Alternatively, addition of DMAP (DMAP = 4-(dimethylamino)pyridine) to [2](+) results in coordinatio

270 Ph2 NSiMe3)2; Mes = 2,4,6-Me3C6H2; DMAP = 4-(dimethylamino)pyridine) which exhibits the unprecedented

271 Using 4-(dimethylamino)pyridine, a corresponding Lewis-base adduc

272 Lewis bases [THF, 4-(dimethylamino)pyridine, and PMe(3)] coordinate to the si

273 OR > O(2)CR, but in the presence of added 4-(dimethylamino)pyridine, DMAP (1 equiv), the order is cha

274 FeL(n) (L = N(2), n = 1,2; CO, n = 2; 4-(N,N-dimethylamino)pyridine, n = 1) resulted in a doubly redu

275 AP [1, 3-(2,2,2-triphenyl-1-acetoxyethyl)-4-(dimethylamino)pyridine] has been prepared from 3-lithio-

276 chloride in CH(2)Cl(2) in the presence of 4-(dimethylamino)-pyridine (DMAP) plus N,N-diisopropylethyl

277 ullerene-carboxylic acid (C60A) and either a dimethylamino-pyridine (DMAP) or a phenothiazine-pyridin

278 th cyanogen bromide (CNBr) or with 1-cyano-4(dimethylamino)-pyridinium tetrafluoroborate (CDAP) to fo

279 I)](+) (2; L(Me(2))N = N,N-bis(2-[2-(N',N'-4-dimethylamino)pyridyl]ethyl)methylamine) is described, t

280 Here we use this substrate, 4-(4-(dimethylamino)styrl)-N-methyl-pyridinium (ASP+), in comb

281 opamine (DA) transporter (DAT), termed 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP+), to illu

282 using a fluorescent substrate of DAT, 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP+).

283 the fluorescent DAT substrate ASP(+) [4-(4-(dimethylamino)styryl)-N-methylpyridinium] revealed that

284 y of the 4-(di-cyanomethylene)-2-methyl-6-p-(dimethylamino)styryl-4H-pyran (DCM) laser dye in deutera

285 t dopamine transporter substrate trans-4-[4-(dimethylamino)styryl]-1-methylpyridinium (ASP(+)) in hum

286 dition of electron-donating groups such as a dimethylamino substituent at the 7 position greatly enha

287 Under neutral conditions, the dimethylamino substituent coordinates to the ruthenium c

288 is achieved by a combined ortho-CN and meta-dimethylamino substituent electronic effect that largely

289 Mechanistic studies show that the dimethylamino substituent is partially dissociated from

290 d by molecular modeling, we replaced the N,N-dimethylamino substituents in tetramethylrhodamine with

291 -9,10-dione] by reduction of the N-oxides to dimethylamino substituents.

292 Compound 9u (with a dimethylamino substitution) was the most active inhibito

293 sults led to the finding that daminozide (N-(dimethylamino)succinamic acid, 160 Da), a plant growth r

294 alkenylsilane reagents and 1.5 equiv of tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF)

295 on will form by reaction of silane with tris(dimethylamino)sulfonium difluorotrimethylsilicate (TASF)

296 Structural studies confirmed this N,N-dimethylamino tail moved toward the DFG motif to form a

297 Indeed, introduction of an N,N-dimethylamino tail resulted in 4b, which showed almost 5

298 nctional-group tolerant, with alkene, ether, dimethylamino, trifluoromethyl, ester, cyano, halide, hy

299 moted aza-Diels-Alder reaction between 6-[2-(dimethylamino)vinyl]-1,3-dimethyluracil and aldimines ha

300 sisting of triazacryptand coupled to 3,6-bis(dimethylamino)xanthylium, whose fluorescence increased 1