ライフサイエンスコーパス: dinucleotide repeat

1 includes a polypyrimidine-rich region and CA dinucleotide repeat.

2 in repetitive DNA, requiring as little as a dinucleotide repeat.

3 ir association with homopolymeric tracts and dinucleotide repeats.

4 AST phenotype and low levels of mutations at dinucleotide repeats.

5 which defines a novel function for exonic CA dinucleotide repeats.

6 rn of the mutation rate variation within the dinucleotide repeats.

7 lexibility of two kinds of nicked DNA and AT dinucleotide repeats.

8 ibit microsatellite instability at mono- and dinucleotide repeats.

9 The gene has several stretches of dinucleotide repeats.

10 y been shown that this mutation destabilizes dinucleotide repeats 150-fold and that this effect is pr

11 airs (bp) upstream of the start site, and GT dinucleotide repeats 50 to 800 bp downstream in the plus

12 A novel polymorphic dinucleotide repeat, 6E3.2, present in one of the ordere

13 inated sequence (IES) is bounded by 5'-TA-3' dinucleotide repeats, a feature common to some classes o

14 A survey of dinucleotide repeats across the entire Arabidopsis genom

15 etected as induced instability of a (CA)(29) dinucleotide repeat and by increased mutagenesis in a ch

16 The inheritance of an intronic dinucleotide repeat and seven single nucleotide polymorp

17 ning simple repeats, including 28 (55%) with dinucleotide repeats and 6 (11%) with trinucleotide repe

18 s including single nucleotide polymorphisms, dinucleotide repeats and microsatellites have been ident

19 yzed as haplotypes consisting of each of the dinucleotide repeats and the flanking Alu insertion/dele

20 Most frameshifts were detected within dinucleotide repeats and there were prominent mutational

21 e had a strongly elevated mutation rate in a dinucleotide repeat, and the rate was not further elevat

22 s, the Bethesda consensus panel of mono- and dinucleotide repeats, and coding mononucleotide repeats

23 Mononucleotide and dinucleotide repeats are rarely found in ORFs, and when

24 Dinucleotide repeats are ubiquitous features of eukaryot

25 d inexact repeat lengths (e.g., 1.9 bp for a dinucleotide repeat), are accommodated by the method and

26 ta = 0 was observed with a fully informative dinucleotide repeat at COL4A5, and flanking recombinatio

27 CpG dinucleotide repeats at 10 bp intervals were found to pl

28 Notably, the dinucleotide repeats [AT]n, [AC]n, and [AG]n are signifi

29 this allele does not alter mutation rates at dinucleotide repeats, at nonrepeating sequences, or for

30 phenotype was specific, as mutation rates at dinucleotide repeats, at unique sequences, or for TNR co

31 Dinucleotide repeats, because of their repetitive nature

32 reading frame but did include a polymorphic dinucleotide repeat (CA)17.

33 Taken together, these data indicate that dinucleotide repeats can form secondary structures that

34 alleles with greater numbers (12 or more) of dinucleotide repeats, compared with 9 of 11 cases with g

35 r a pyrimidine rich region consisting of two dinucleotide repeats containing 23 and 20 TC pairs separ

36 In barley, characterization of 290 dinucleotide repeat-containing clones from SSR-enriched

37 frequency data from 115 microsatellites with dinucleotide repeats distributed along the human genome

38 also identified a highly polymorphic simple dinucleotide repeat DNA polymorphism in this gene that w

39 Dinucleotide repeat DNA with the pattern (GA)(n)/(TC)(n)

40 Substitution of the dinucleotide-repeat-element with a non-Z-DNA-forming seq

41 an uncommon event, genotyping of polymorphic dinucleotide repeat elements from 4 different chromosoma

42 Direct TA dinucleotide repeats exist at the termini of all CREE.

43 e susceptibility to glomerulosclerosis, that dinucleotide repeat expansion may be a novel mechanism f

44 induces both clonal selection and reversible dinucleotide repeat expansion.

45 , consisting of the allele frequency of 5252 dinucleotide repeats from the Genome Database.

46 ied a highly polymorphic chromosome 2q21-q33 dinucleotide repeat genetic marker (D2S141) physically l

47 t cancer, we genotyped a newly identified GT dinucleotide repeat [(GT)(n)] polymorphism located in th

48 the effect on homologous recombination of a dinucleotide repeat, (GT)29, which has been shown to sti

49 ide repeat were much lower than those of the dinucleotide repeat in both cell types.

50 measured the spontaneous mutation rate of a dinucleotide repeat in diploid human foreskin fibroblast

51 n EGFR overexpression and the length of a CA dinucleotide repeat in intron 1 was observed, a variant

52 A polymorphic dinucleotide repeat in the fifth intron allowed us to ma

53 We also find a variable length (CA)-dinucleotide repeat in the second intron, which may have

54 ertions and deletions of integral numbers of dinucleotide repeats in a microsatellite sequence.

55 and the presence of homopolymeric tracts and dinucleotide repeats in coding sequences, H. pylori, lik

56 High levels of MSI at mononucleotide and dinucleotide repeats in colorectal cancer (CRC) are attr

57 or EMAST with low levels of MSI at loci with dinucleotide repeats in CRC.

58 nged by HP0638 knockout had five or seven CT dinucleotide repeats in the 5' region, resulting in a fr

59 e length polymorphism of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promot

60 e allelic frequencies of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promot

61 ion, a greater number of guanosine thymidine dinucleotide repeats in the heme oxygenase-1 gene promot

62 Length polymorphisms in the number of GT dinucleotide repeats in the HO-1 gene (HMOX1) promoter i

63 anucleotide repeats, but an exception is the dinucleotide repeats in the pilin locus.

64 The potential use of dinucleotide repeats in this manner would represent a no

65 lleles were characterized: two carry a 24 TA dinucleotide repeat insertion in the 5'-upstream promote

66 Because dinucleotide repeat instability is known to increase whe

67 A (GT)(n) dinucleotide repeat located in the promoter region of th

68 calized and specifically bind in vitro to GA dinucleotide repeats located within POS9.

69 Three dinucleotide repeat loci also were examined.

70 from radiation-reduced hybrids, polymorphic dinucleotide repeat loci, and end sequences of YACs and

71 However, the highly variable nature of dinucleotide repeats makes them particularly interesting

72 kers, one located in intron 8 and another, a dinucleotide repeat marker, AFMa086wg9, located within i

73 rmative gastric adenocarcinomas using two 5q dinucleotide repeat markers for LOH analysis.

74 dic PD, and 180 matched normal controls with dinucleotide repeat markers in these genes.

75 se-control study and included 10 polymorphic dinucleotide repeat markers linked to CYP2D6 to determin

76 YP2D6 and Parkinson's disease, but two of 10 dinucleotide repeat markers linked to CYP2D6 were associ

77 sease that is in linkage disequilibrium with dinucleotide repeat markers mapping near CYP2D6 on ch22q

78 bility (MSI-L) when analysed using mono- and dinucleotide repeat markers, and showed a significant ex

79 lymorphic sites and linkage analysis of four dinucleotide repeat markers, two within and two flanking

80 reened the human genome with 300 polymorphic dinucleotide-repeat markers using an unconventional stra

81 f the 74-member pedigree were genotyped with dinucleotide-repeat markers.

82 s in MMR genes of H. influenzae strain Rd on dinucleotide repeat-mediated PV rates was investigated b

83 ave been limited only to the p-1562 and (CA) dinucleotide repeat microsatellite polymorphisms in the

84 We estimate that dinucleotide repeat microsatellites are an average of 3.

85 h repair (MMR) and is defined with mono- and dinucleotide repeat microsatellites.

86 e deficit of diversity is less for SSRs with dinucleotide repeat motifs than for SSRs with repeat mot

87 on and observed the same correlation between dinucleotide repeat number and exon 9 splicing efficienc

88 change within d(TG/AC)n, one of the frequent dinucleotide repeats of the mammalian genome.

89 o changes in mutation rate were observed for dinucleotide repeats or at the CAN1 reporter gene.

90 The CT dinucleotide repeat pattern in the putative HP0638 signa

91 rains in which HP0638 was in frame, a six-CT dinucleotide repeat pattern was dominant in Western coun

92 The HP0638 frame status and CT dinucleotide repeat patterns were identical for 9 of 11

93 Mb, formatted with 200 STSs that include 25 dinucleotide repeat polymorphic markers and more than 80

94 A CA dinucleotide repeat polymorphism (5'ALR2; located at -21

95 A dinucleotide repeat polymorphism in a tau intron was ide

96 Results of this study indicate that the GT dinucleotide repeat polymorphism in ER-alpha gene promot

97 equences of all intron/exon boundaries and a dinucleotide repeat polymorphism in intron 16.

98 Allografts were assessed by (Ca)n dinucleotide repeat polymorphism studies in cells from p

99 Recently, a dinucleotide repeat polymorphism was identified in the p

100 These dinucleotide repeat polymorphisms were detected in chrom

101 Dinucleotide repeat polymorphisms were identified after

102 combination with one of a panel of anchored dinucleotide repeat primers.

103 gth heteroplasmy was also observed in the AC dinucleotide repeat region, as well as other locations.

104 tability of endo-gen-ous tetranucleotide and dinucleotide repeat sequen-ces.

105 s in rates of frameshift mutations between a dinucleotide repeat sequence [(CA)(17)] and a tetranucle

106 We used a polymorphic dinucleotide repeat sequence in a genomic clone of NACP

107 We have introduced a dinucleotide repeat sequence into the telomerase-express

108 Our previous report shows that a d(CG)n dinucleotide repeat sequence located proximally upstream

109 In this article, the effect of a d(CG) DNA dinucleotide repeat sequence on RNA polymerase II transc

110 eam of the polyadenylation site in exon 6, a dinucleotide repeat sequence was identified.

111 e specificity for the loss of two bases in a dinucleotide repeat sequence within the HSV-tk locus.

112 en the 2-nucleotide gap is associated with a dinucleotide repeat sequence, sequence slippage re-align

113 The NRE contains a stretch of dinucleotide-repeat sequence that is able to adopt a Z-D

114 Recombinant GBP protein did not bind to dinucleotide repeat sequences other than (GA)(n)/(CT)(n)

115 ates of mutations, particularly at mono- and dinucleotide repeat sequences.

116 rmostable DNA ligases was measured for model dinucleotide repeat sequences.

117 buffer also increased ligation fidelity for dinucleotide repeat sequences.

118 , we measured insertion-deletion mutation of dinucleotide-repeat sequences (microsatellite instabilit

119 lternative, MSH3-like activity that restored dinucleotide repeat stability and sensitivity to chromat

120 An example of a variable dinucleotide repeat that affects splicing is a TG repeat

121 gle-unit insertion/deletion in a 5' flanking dinucleotide repeat that governs expression of each vmc

122 an AT-rich region that contains a dA/dT(23) dinucleotide repeat that has properties of a DNA unwindi

123 Dinucleotide repeat tracts are destabilized by mismatch

124 ous to the E. coli MMR pathway and active on dinucleotide repeat tracts, defects in H. influenzae MMR

125 hin the larger introns include a polymorphic dinucleotide repeat, two tandem repeats, and a putative

126 The GLYT-1 gene contains three sets of dinucleotide repeats, two AC repeats, and one TG repeat

127 ed oligonucleotides on ligation fidelity for dinucleotide repeats was determined using the nucleoside

128 rosatellite loci containing trinucleotide or dinucleotide repeats were amplified from infected tissue

129 n all cases, the mutation frequencies of the dinucleotide repeats were higher than those of the tetra

130 tations in spel1 decrease the stability of a dinucleotide repeat when it is copied into the site of a

131 ncreased rate of instability in long runs of dinucleotide repeats when analyzed after 10-12 fly gener

132 (16-fold) elevation in the instability of a dinucleotide repeat, whereas Msh2-deficient and Msh2 Msh

133 ted increase element (AIE; unique stretch of dinucleotide repeats), which were responsible for age-re

134 CA)13-EGFP, a plasmid that contains a (CA)13 dinucleotide repeat, which disrupts the reading frame of

135 The homopolymeric nucleotide tracts and dinucleotide repeats, which potentially regulate the on-

136 dition, we have identified a new polymorphic dinucleotide repeat within intron 4 of TNFR2.