ライフサイエンスコーパス: dipeptidase

1 been shown to function as a Cys-Gly-specific dipeptidase.

2 e and brain N-acetylated alpha-linked acidic dipeptidase.

3 opeptidase, and peptidase E, an Asp-specific dipeptidase.

4 idase E (PepE) is an N-terminal Asp-specific dipeptidase.

5 d rat brain N-acetylated alpha-linked acidic dipeptidase.

6 eins gamma-glutamyl transpeptidase (GGT) and dipeptidase.

7 nterococci, is a zinc-containing d-Ala-d-Ala dipeptidase.

8 share sequence homology with other bacterial dipeptidases.

9 of overexpression in CRC compared to AT was Dipeptidase 1 (DPEP1).

10 d dipeptidase-3 (MBD-3)] from membrane-bound dipeptidase-1 (MBD-1) deficient mice.

11 found that a protease, cytosolic nonspecific dipeptidase 2 (CNDP2), catalyzes their formation.

12 ein (NLDL), N-acetylated alpha-linked acidic dipeptidase 2 (NAALAD2), and prostate-specific membrane

13 membrane-bound dipeptidases [membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (

14 und dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3)] from membrane-bound dipeptidase-1

15 of control, n = 3, p < .0005) and dipeptidyl dipeptidase (374 +/- 79.1% of control, n = 3, p < .005),

16 we show that inhibitors of mosquito peptidyl dipeptidase, a peptidase related to mammalian angiotensi

17 activity (intralysosome) to a region of high dipeptidase activity (cytosol).

18 transfer of dipeptides from a region of low dipeptidase activity (intralysosome) to a region of high

19 It had very low dipeptidase activity against D-Ala-D-Ser, unlike VanX, a

20 and partially purified native AbpB displayed dipeptidase activity and degraded human type VI collagen

21 tified clinical isolates lacking D-Ala-D-Ala dipeptidase activity and unable to grow on D-Ala-D-Ala b

22 bond showed endopeptidase to be superior to dipeptidase activity for APCE.

23 observed reactivity change from the peptidyl dipeptidase activity of ACE to the carboxypeptidase acti

24 rovar Typhimurium strain contain an aspartyl dipeptidase activity that is dependent on Mn(2+).

25 The pcgL gene conferred D-Ala-D-Ala dipeptidase activity upon Escherichia coli K-12 but did

26 Furthermore, no difference in total cellular dipeptidase activity was detected between the mutant and

27 and the E181A VanX mutant has no detectable dipeptidase activity, yet maintains near-stoichiometric

28 SMA and its N-acelylated-alpha linked-acidic dipeptidase activity.

29 coelution of PM20D2 with beta-alanyl-lysine dipeptidase activity.

30 ain contained a cytosolic beta-alanyl-lysine dipeptidase activity.

31 NAALADase (N-acetylated-alpha-linked-acidic dipeptidase), an enzyme responsible for the hydrolysis o

32 Human renal dipeptidase, an enzyme associated with glutathione metab

33 vity of the brush border enzymes, dipeptidyl dipeptidase and alkaline phosphatase, was assayed by the

34 D-Ala-D-Ser has a polar effect on both D, D-dipeptidase and D,D-carboxypeptidase activities.

35 VanX and VanY have strict D,D-dipeptidase and D,D-carboxypeptidase activity, respectiv

36 tidase, rat N-acetylated alpha-linked acidic dipeptidase, and human prostate-specific membrane antige

37 netically deficient in or overexpressing the dipeptidase angiotensin-converting enzyme (ACE), we have

38 on with a vac-encoded exocytic COOH-terminal dipeptidase, angiotensin converting enzyme, to allow lib

39 ved for the product complexes of isoaspartyl dipeptidase, d-aminoacylase, and dihydroorotase from the

40 giotensin I-converting enzyme (ACE, peptidyl dipeptidase, EC 3.4.15.2) is a key enzyme in cardiovascu

41 rotein is a D-alanyl-D-alanine (D-Ala-D-Ala) dipeptidase essential for resistance to the glycopeptide

42 by binding to the accessory molecule CD26, a dipeptidase expressed on the surface of activated T cell

43 PepV, a dipeptidase found in culture fluids of Streptococcus gor

44 The closest homologue to the human renal dipeptidase from a fully sequenced microbe is Sco3058 fr

45 ivities is a previously characterized isoAsp dipeptidase from E. coli, the product of the iadA gene.

46 Isoaspartyl dipeptidase from Escherichia coli functions in protein d

47 Homology was found with a putative dipeptidase from Streptococcus pyogenes and nonspecific

48 from Streptococcus pyogenes and nonspecific dipeptidases from Lactobacillus helveticus and Lactococc

49 ht end of Tn5382 and downstream of the vanXB dipeptidase gene exhibit significant homology to genes e

50 The Salmonella dipeptidase gene, designated pcgL, appears to have been

51 ndent receptors, two OmpA family proteins, a dipeptidase, GlpQ, two alkaline phosphatases, 3-phytase,

52 Isoaspartyl dipeptidase (IAD) is a member of the amidohydrolase supe

53 gonist, NS5, to prolidase (PEPD), a cellular dipeptidase implicated in primary immune deficiencies in

54 iotensin-converting enzyme (ACE), a peptidyl dipeptidase implicated in regulation of blood pressure a

55 w report the identification of a D-Ala-D-Ala dipeptidase in the gram-negative species Salmonella ente

56 mutant of gene all3922 encoding isoaspartyl dipeptidase in the model heterocyst-forming cyanobacteri

57 alysis confirms the placement of isoaspartyl dipeptidase into the urease-related amidohydrolase super

58 specific cell types showed that isoaspartyl dipeptidase is present at significantly lower levels in

59 ked HBC-3 cells into wild-type or dipeptidyl dipeptidase IV (DPPIV) knockout blastocysts.

60 Using a dipeptidyl dipeptidase IV genetic marker system to follow the fate

61 N-acetylated alpha-linked acidic dipeptidase-like protein (NAALADase L), encoded by the N

62 2 or PSMA), N-acetylated alpha-linked acidic dipeptidase-like protein (NLDL), N-acetylated alpha-link

63 Membrane-bound dipeptidase (MBD) participates in the degradation of glu

64 e developed mice deficient in membrane-bound dipeptidase (MBD, EC 3.4.13.19), the enzyme believed to

65 Membrane dipeptidase (MDP) is a zinc metalloenzyme located in the

66 hed the identity of the receptor as membrane dipeptidase (MDP), a cell-surface zinc metalloprotease i

67 oding previously unidentified membrane-bound dipeptidases [membrane-bound dipeptidase-2 (MBD-2) and m

68 zing enzyme N-acetylated alpha-linked acidic dipeptidase (NAAG peptidase activity) or glutamate carbo

69 nhibition of xPSM N-acetyl-alpha-linked acid dipeptidase (NAALADase) enzymatic activity.

70 rain enzyme N-acetylated alpha-linked acidic dipeptidase (NAALADase) has been shown to remove sequent

71 N-acetylated alpha-linked acidic dipeptidase (NAALADase) hydrolyzes acidic peptides, such

72 en known as N-acetylated alpha-linked acidic dipeptidase (NAALADase), and is identical to the prostat

73 ropeptidase N-acetylated alpha-linked acidic dipeptidase (NAALADase).

74 ties of the N-acetylated alpha-linked acidic dipeptidase (NAALADase).

75 Prolidase, also known as Xaa-Pro dipeptidase or peptidase D (PEPD), is a ubiquitously exp

76 ic space of Salmonella, suggesting that this dipeptidase participates in peptidoglycan metabolism.

77 Previously, the gene for a general dipeptidase (pepDA) was isolated from a gene bank of Lac

78 structure of Salmonella typhimurium aspartyl dipeptidase, peptidase E, was solved crystallographicall

79 des of the X-proline type are cleaved by the dipeptidase prolidase.

80 The effects of the compounds on X-Pro dipeptidase (prolidase) and leucyl aminopeptidase are al

81 Proline dipeptidase (prolidase) was purified from cell extracts

82 Quiescent cell proline dipeptidase (QPP) is an intracellular serine protease th

83 ovel serine protease, quiescent cell proline dipeptidase (QPP), with substrate specificity similar to

84 e that we have termed quiescent cell proline dipeptidase (QPP).

85 protein with sequence similarity to VanX, a dipeptidase required for resistance to vancomycin.

86 ted both alkaline phosphatase and dipeptidyl dipeptidase specific activity by 116 +/- 5.4% and 256 +/

87 enterica harbours a periplasmic D-Ala-D-Ala dipeptidase (termed PcgL), which confers the ability to

88 VanX is a zinc-dependent D-alanyl-D-alanine dipeptidase that is a critical component in a system tha

89 eptidase IV (DP-IV) is a cell surface serine dipeptidase that is involved in the regulation of the in

90 Biosynthesis of MCTR3 was mediated by dipeptidases that cleaved the cysteinyl-glycinyl bond of

91 ases beta-aspartyl-arginine) and isoaspartyl dipeptidase (that produces aspartate and arginine).

92 ovel serine protease, quiescent cell proline dipeptidase, that we have recently isolated and cloned.

93 -containing D-alanyl-D-alanine (D-Ala-D-Ala) dipeptidase VanX has been detected in both Gram-positive

94 ptidase and N-acetylated alpha-linked acidic dipeptidase, while immunoblots using monoclonal antibody

95 y X-ray crystallography and reveals a Zn(2+)-dipeptidase with a unique overall fold and a well-define

96 have shown that it is indeed an Asp-specific dipeptidase with properties very similar to those of ser

97 proteins currently annotated as nonspecific dipeptidases within the amidohydrolase superfamily.