ライフサイエンスコーパス: diphenylene

1 oluble organic radicals containing a 1,3-bis(diphenylene)-2-phenylallyl (BDPA) core is reported.

2 ign and synthesis of a water-soluble 1,3-bis(diphenylene)-2-phenylallyl (BDPA) radical via the conjug

3 ADPH oxidase, and the flavoprotein inhibitor diphenylene iodinium (DPI) block TSP2 synthesis.

4 g(H)-V) relationship was shifted -43 mV, and diphenylene iodinium (DPI)-inhibitable inward current re

5 AA activated diphenylene iodinium (DPI)-inhibitable inward current re

6 Diphenylene iodinium also reversed the slowing of tau(ta

7 Diphenylene iodinium inhibited this increase in O(2)(*)(

8 current was confirmed by its sensitivity to diphenylene iodinium, an inhibitor of NADPH oxidase.

9 ession in RPTCs, whereas rotenone, catalase, diphenylene iodinium, and apocynin decreased it.

10 inhibitors of either flavoprotein oxidases (diphenylene iododonium) or NOX enzymes (GKT136901).

11 th ebselen (3.6 +/- 0.2 versus 1.1 +/- 0.2), diphenylene iodonium (3.6 +/- 0.2 versus 1.0 +/- 0.1), a

12 ion was inhibited by NADPH oxidase inhibitor diphenylene iodonium (DPI) and mitochondria electron cha

13 Addition of the antioxidant diphenylene iodonium (DPI) diminished DMXAA-induced IFN-

14 The presence of diphenylene iodonium (DPI) inhibited ROS production by U

15 cking the activity of the NADPH oxidase with diphenylene iodonium (DPI) inhibits ROS formation and ph

16 cells could be attenuated in the presence of diphenylene iodonium (DPI), an inhibitor of the NADPH ox

17 inhibited by an inhibitor of NADPH oxidase, diphenylene iodonium (DPI), and by antioxidants, N-acety

18 ed by NADPH oxidase inhibitors, apocynin and diphenylene iodonium (DPI), but not the xanthine/xanthin

19 as inhibited by the NADPH oxidase inhibitors diphenylene iodonium (DPI), imidazole, and pyridine.

20 gene expression was inhibited by antioxidant diphenylene iodonium (DPI), which is consistent with the

21 nd Tiron (5 mmol/L) and the flavin-inhibitor diphenylene iodonium (DPI, 20 micromol/L) abolished nore

22 tion in LPS-stimulated HMs were inhibited by diphenylene iodonium (nonspecific inhibitor for flavin-c

23 ial cells with the NAD(P)H oxidase inhibitor diphenylene iodonium abolishes RSV-induced STAT activati

24 Scavenging reactive oxygen species with diphenylene iodonium also blocks both priming and ERK ph

25 vious studies with NADPH oxidase inhibitors, diphenylene iodonium and apocynin, suggested that NADPH

26 hils treated with the flavoprotein inhibitor diphenylene iodonium and in neutrophils from patients wi

27 gnificantly retarded in the presence of both diphenylene iodonium and MnTMPyP.

28 trast, inhibitors of NADPH oxidase activity, diphenylene iodonium and staurosporine, as well as antio

29 The NADPH inhibitor diphenylene iodonium and the superoxide dismutase mimeti

30 t ascorbate, or the ROS-generation inhibitor diphenylene iodonium attenuated gravitropism while enhan

31 Antioxidants and the oxidase inhibitor diphenylene iodonium blocked ERK phosphorylation, but sp

32 ocalized near nectary pores and inhibited by diphenylene iodonium but not by cyanide or azide, sugges

33 re treated with the NADPH oxidase inhibitors diphenylene iodonium chloride and apocynin.

34 The NADPH oxidase inhibitor diphenylene iodonium chloride did not affect the calcium

35 Cu) and inhibitors of NADPH oxidases (e.g., diphenylene iodonium chloride), enzymes responsible for

36 s, and in wild-type plants by treatment with diphenylene iodonium chloride, an inhibitor of hydrogen

37 endent production of hydrogen peroxide via a diphenylene iodonium chloride-sensitive calcium-dependen

38 en, catalase, and the flavoprotein inhibitor diphenylene iodonium each attenuated PDGF- and Rac1-medi

39 dies and inhibition experiments using CO and diphenylene iodonium indicate that only the low spin hem

40 wever, the antioxidants N-acetylcysteine and diphenylene iodonium inhibited both AA- and Ang II-induc

41 Treatment of cells with diphenylene iodonium inhibited virus-induced oxidative s

42 etylcysteine or the flavin protein inhibitor diphenylene iodonium is demonstrated to reduce oxidant l

43 e, which generates superoxide and H2O2, with diphenylene iodonium or apocynin decreased Ang II-induce

44 reatment of rat VSMCs with the NOX inhibitor diphenylene iodonium or the antioxidants N-acetylcystein

45 In addition, NADPH oxidase inhibitor diphenylene iodonium significantly inhibited the TDCA-in

46 Inhibitors of Rac1 (NSC23766), NOX (diphenylene iodonium), and NOX1 (small interfering RNA [

47 alone, 5.0+/-1.1-fold; NAC, 1.8+/-0.2-fold; diphenylene iodonium, 1.4+/-0.3-fold migration; and ebse

48 with a farnesyltransferase inhibitor or with diphenylene iodonium, a flavoprotein inhibitor.

49 was effectively blocked by pretreatment with diphenylene iodonium, a NADPH oxidase inhibitor.

50 ss, ERL-induced cytotoxicity was reversed by diphenylene iodonium, a NOX complex inhibitor.

51 Furthermore, diphenylene iodonium, an inhibitor of flavin-containing

52 (ROS) dependent because it was inhibited by diphenylene iodonium, an inhibitor of NADPH oxidase, and

53 and was inhibited by 1-methylcyclopropene or diphenylene iodonium, an inhibitor of NADPH oxidase.

54 s H2O2 activates only p38MAPK (14-fold), and diphenylene iodonium, an NADH/NADPH oxidase inhibitor, a

55 ects were attenuated by N-acetylcysteine and diphenylene iodonium, an NADPH oxidase inhibitor.

56 inhibited by the NAD(P)H oxidase inhibitor, diphenylene iodonium, as well as by overexpression of do

57 nhibitor of flavoprotein-dependent oxidases, diphenylene iodonium, but not by inhibitors of various o

58 eine, the flavin-containing enzyme inhibitor diphenylene iodonium, or the glutathione peroxidase mime

59 NADPH oxidase function through the inhibitor diphenylene iodonium, the superoxide dismutase mimetic M

60 two inhibitors of ROS generation, azide and diphenylene iodonium, we found that perxoxidases generat

61 as abrogated by N-acetyl cysteine but not by diphenylene iodonium, which displayed prooxidant activit

62 an Arabidopsis thaliana azide-sensitive but diphenylene iodonium-insensitive apoplastic oxidative bu

63 njury correlated with the acute induction of diphenylene iodonium-sensitive NADPH-dependent superoxid

64 n (IL)-1beta stimulation of SMCs resulted in diphenylene iodonium-sensitive ROS production within int

65 or the NADPH oxidase inhibitors apocynin or diphenylene iodonium.

66 but was inhibited by the flavoenzyme blocker diphenylene iodonium.

67 uction was prevented by N-acetylcysteine and diphenylene iodonium.

68 acetylcysteine and a flavoprotein inhibitor, diphenylene iodonium.

69 ocarbamate, and the NADPH oxidase inhibitor, diphenylene iodonium.

70 NO), and by a nonspecific oxidase inhibitor, diphenylene iodonium.

71 nd mouse HSCs by the NADPH oxidase inhibitor diphenylene-iodonium (DPI) and in HSCs lacking the NADPH

72 mplex, which contains a catalytically active diphenylene squaramide moiety and two hydrogen-bond-acce

73 Thus, the diphenylene squaramide moiety is able to catalyze a Frie

74 ule, such as poly(para-phenylene), poly(4,4'-diphenylene vinylene) or polyfluorene through alpha- or