ライフサイエンスコーパス: diploid cell

1 on of male and female haploid gametes into a diploid cell.

2 isolated cytogenetic finding in an otherwise diploid cell.

3 from only one of two homologous alleles in a diploid cell.

4 regation yield four haploid gametes from one diploid cell.

5 ts influence expression of both alleles in a diploid cell.

6 ifferences in expression of two alleles in a diploid cell.

7 disadvantage of haploid cells compared with diploid cells.

8 DNA ploidy but results in immortalization of diploid cells.

9 /Bud10 in haploid cells and Bud8 and Bud9 in diploid cells.

10 nhances the invasive behavior of haploid and diploid cells.

11 sting it is imported via the same pathway in diploid cells.

12 of different mating type combine to produce diploid cells.

13 ortalized human cell lines as well as normal diploid cells.

14 mine chromatin organization in polyploid and diploid cells.

15 operate during initiation of instability in diploid cells.

16 phase transition of NIH 3T3 and normal human diploid cells.

17 complexes repress haploid-specific genes in diploid cells.

18 tioned adjacent to the a1-alpha2 operator in diploid cells.

19 odifications increased cytotoxicity in human diploid cells.

20 he vast majority of oocytes enter meiosis as diploid cells.

21 id cells and is necessary for sporulation in diploid cells.

22 r inactive X alleles present in normal human diploid cells.

23 in complete remission, all but 2 showed all diploid cells.

24 populations had the allelic loss present in diploid cells.

25 as affected, as demonstrated in heterozygous diploid cells.

26 e to environmental stresses not tolerated by diploid cells.

27 but does not obviously affect proliferating diploid cells.

28 is a clear determinant of gene expression in diploid cells.

29 referentially sensitive to AICAR compared to diploid cells.

30 etween human embryonic stem (hES) and normal diploid cells.

31 e, we examine genetic stability in tel1 mec1 diploid cells.

32 not seen in vegetatively dividing haploid or diploid cells.

33 Mmi1 cause high levels of UPD in vegetative diploid cells.

34 uirement for Plk1 than normal nontransformed diploid cells.

35 oses generates CIN in otherwise stable, near-diploid cells.

36 ic imprinted expression in the reconstructed diploid cells.

37 ement, producing haploid gametes/spores from diploid cells.

38 of template DNA, which is equivalent to 1-2 diploid cells.

39 MIP1, to be evaluated in vivo in haploid and diploid cells.

40 in organisms that are primarily comprised of diploid cells.

41 ence of a competing homologous chromosome in diploid cells.

42 er, were reduced in tetraploid compared with diploid cells.

43 The genetic data indicate that in a diploid cell, a heterozygous deletion mutation in the ge

44 In MATa/MATalpha diploid cells, a DSB induced by HO endonuclease was repa

45 -prostate cancer cells, including WI-38 lung diploid cells, A-431 epidermoid carcinoma cells, and HeL

46 Cultures enriched with not-diploid cells acquired a senescence-associated secretory

47 n mating-type gene expression in haploid and diploid cells affect NHEJ function, resulting in distinc

48 hat ethanol stimulates hyperfilamentation in diploid cells, again in a MAPK-dependent manner.

49 bition of Hsp90 with macbecin in sporulating diploid cells also blocked spore formation, underscoring

50 Nonswitching diploid cells also express Ash1, suggesting it could hav

51 clear homodimers in contact inhibited normal diploid cells and dimerization of p12 is a necessary pro

52 Both suppressor genes are dominant in diploid cells and lethal in haploid cells.

53 d poliovirus vaccine (IPV) produced in human diploid cells and live attenuated oral poliovirus vaccin

54 This system uses diploid cells and provides the possibility for allelic r

55 deletions of one copy of essential genes in diploid cells and purified spores containing the deletio

56 gnificant correlations between levels of not-diploid cells and senescence-associated features (SAFs).

57 ersions of the G subunit were expressed in a diploid cell, and affinity purification of cytosolic V1

58 on morphology, bipolar bud site selection in diploid cells, and cell separation.

59 ng force in the evolution of mitotic/somatic diploid cells, and cellular changes that increase the ra

60 YAR1 is transcribed in both haploid and diploid cells, and in haploid cells arrested in G1 with

61 cterized using a large dataset of 129 normal diploid cells, and is shown to exceed previously reporte

62 that the replication profiles of haploid and diploid cells are indistinguishable, indicating that bot

63 ly stall at such barriers in late S phase of diploid cells are left unresolved in the shortened S pha

64 The proportion of diploid cells, as determined by flow cytometry, varied f

65 null-targeting method can be applied to any diploid cell, at any locus for which a negative selectio

66 CDKN2 mutations develop as early lesions in diploid cells before aneuploidy and cancer during neopla

67 haploid cells bud in an axial manner, while diploid cells bud in a bipolar manner.

68 In diploid cells, but not in chromosomally unstable cells,

69 ia, however, FLO11 transcripts accumulate in diploid cells, but not in haploids.

70 Growth arrest of normal diploid cells by contact inhibition resulted in an induc

71 In contrast, diploid cells cannot mate because genes that encode comp

72 of both RST1 and RST2 (rst-) causes a/alpha diploid cells constitutively to express a-specific genes

73 active new system to address how postmitotic diploid cells contribute to repair.

74 we propose that Ume6 serves a unique role in diploid cells, coupling metabolic responses to nutrition

75 demonstrates that the loss of FoxM1 elicits diploid cell deficiency with enhanced arrests prior to m

76 ortex; in particular, the bipolar budding of diploid cells depends on persistent landmarks at the bir

77 To study the phenotype of C. albicans diploid cells depleted of CaCse4p, we deleted one copy o

78 We show here that normal diploid cells derived from AT patients do not exhibit co

79 ng regulation occurs during meiosis in which diploid cells divide to form haploid gametes.

80 but its function is not required for normal diploid cell division.

81 Colonies initiated with aged diploid cells do not show disadvantage in colony expansi

82 of accurately genotyping DNA from one single diploid cell equivalent.

83 A replication and promoting proliferation in diploid cells, even when developmental signals normally

84 xhibit an axial budding pattern, and a/alpha diploid cells exhibit a bipolar pattern.

85 it an axial budding pattern, whereas a/alpha diploid cells exhibit a bipolar pattern.

86 midway through meiosis, and homozygous ssp1 diploid cells fail to sporulate.

87 neage undergo mitotic proliferation to yield diploid cells, followed by endomitosis and acquisition o

88 of filamentous growth was also observed for diploid cells following MEK/ERK expression in liquid cul

89 ynamics observed in vivo in both haploid and diploid cells follows a process of dissociation-aggregat

90 velopmental switch: when FLO11 is expressed, diploid cells form pseudohyphal filaments; when FLO11 is

91 losses were also found in the corresponding diploid cells from premalignant epithelium in all three

92 In eukaryotes, diploid cells give rise to haploid cells via meiosis, a

93 siae is a highly regulated process wherein a diploid cell gives rise to four haploid gametes.

94 Meiosis is the cellular program by which a diploid cell gives rise to haploid gametes for sexual re

95 tion of interphase is similar in haploid and diploid cells, haploid cells spend longer in mitosis, in

96 tract-length changes are half as frequent in diploid cells harboring heterozygous HRAS1 minisatellite

97 Normal diploid cells have a limited replicative potential in cu

98 We show that normal diploid cells have a more robust error-correction machin

99 We show here that cultured normal human diploid cells have longer G overhangs at telomeres gener

100 Most normal human diploid cells have no detectable telomerase; however, ex

101 In wild-type diploid cells, heteroallelic recombination between his4A

102 cells: (i) normal telomerase-negative human diploid cells; (ii) normal cells transfected with the hu

103 acking of the two copies of the GAL locus in diploid cells in both activating and repressive conditio

104 egulated in meiosis-competent MATa/MAT alpha diploid cells in comparison with diploids or haploids ex

105 no drug-resistant mutants were obtained from diploid cells in our conditions.

106 yeast Saccharomyces cerevisiae is induced in diploid cells in response to nitrogen starvation and abu

107 romatin we have established 'isogenic' human diploid cells in which PARP1 and/or PARP2, or PARP3 are

108 o developed a protocol for null targeting of diploid cells, in which transfection of a DHFR-TS deleti

109 segregation compromises the proliferation of diploid cells, indicating that phenotypic changes that p

110 ed in G(1), S, and M phases and from meiotic diploid cells, indicating that they are constitutive com

111 a significant increase in the proportion of diploid cells, indicative of cell cycle arrest in G0-G1,

112 In Arabidopsis thaliana, a single diploid cell is specified as the premeiotic female gamet

113 nclear because the proliferation of cultured diploid cells is compromised by chromosome missegregatio

114 However, conditional gene inactivation in diploid cells is still difficult to achieve.

115 Both haploid and diploid cells lacking Akr1p grow slowly and develop defo

116 Loss of Nm23-H1 in diploid cells leads to cytokinetic furrow regression, fo

117 ell lines and compared to those on a healthy diploid cell line for cellular cytotoxicity.

118 Transfection of this stably diploid cell line with genomic DNA fragments from a huma

119 ctation for elements ascertained in a single diploid cell line.

120 xisting Dryvax vaccine for growth in a human diploid cell line.

121 traploid isogenic cells that had arisen from diploid cell lines displayed lower drug sensitivity than

122 nd apoptosis in cancer cells, whereas normal diploid cell lines, hTERT-RPE1 and MCF10A, survived a si

123 bsence of RAD52, repair is nearly absent and diploid cells lose the broken chromosome; however, in ce

124 tumors, but the mechanisms by which a stable diploid cell loses the ability to maintain genomic integ

125 In normal diploid cells, malattachments arise spontaneously and ar

126 p53 inactivation and c-myc overexpression in diploid cells markedly accelerates the spontaneous devel

127 educe the states of chromatin folding in the diploid cell nucleus.

128 ring phenotypes of recessive genes in normal diploid cells of about 10(-12).

129 Diploid cells of budding yeast produce haploid cells thr

130 Diploid cells of Chlamydomonas reinhardtii that are hete

131 he conservation of TADs between polytene and diploid cells of Drosophila.

132 resses this subject for vegetatively growing diploid cells of fission yeast Schizosaccharomyces pombe

133 In the diploid cells of most organisms, including humans, each

134 e ratio of normal to aneuploid nuclei in the diploid cells of patients with impaired spermatogenesis

135 In response to starvation, diploid cells of Saccharomyces cerevisiae undergo meiosi

136 In wild-type diploid cells of Saccharomyces cerevisiae, an HO endonuc

137 Diploid cells of the budding yeast Saccharomyces cerevis

138 In response to nitrogen starvation, diploid cells of the budding yeast Saccharomyces cerevis

139 Starvation of diploid cells of the budding yeast Saccharomyces cerevis

140 consequences of removing one copy of MAD2 in diploid cells of the budding yeast, Saccharomyces cerevi

141 salivary gland but not in the predominantly diploid cells of the embryo or larval imaginal discs and

142 In response to nitrogen starvation, diploid cells of the yeast Saccharomyces cerevisiae diff

143 Nitrogen-starved diploid cells of the yeast Saccharomyces cerevisiae diff

144 Diploid cells of the yeast Saccharomyces cerevisiae form

145 In response to nitrogen limitation, diploid cells of the yeast Saccharomyces cerevisiae unde

146 ion in the presence of a poor carbon source, diploid cells of the yeast Saccharomyces cerevisiae unde

147 In diploid cells of the yeast Saccharomyces cerevisiae, the

148 se regulatory pathways that also function in diploid cells, particularly those involved in S phase en

149 rol, nitrogen starvation, or sporulation (in diploid cells) pathways.

150 e regulation of genes specific to haploid or diploid cells plays a key role in determining which path

151 p53-mutant clones, including diploid cell populations, underwent expansion from 1 to

152 chanisms are likely to synergize to maintain diploid cell populations.

153 tify a population of proliferating Blimp1(+) diploid cells present within the spongiotrophoblast laye

154 Diploid cell progenitors with somatic genetic or epigene

155 These results suggest that in normal diploid cells, Ras proteins regulate oxidant production

156 Direct knockdown of H19 expression in diploid cells resulted in acquisition of polyploid cell

157 Normal human diploid cells senesce in vitro and in vivo after a limit

158 In diploid cells, sir mutants showed a twofold reduction in

159 In its absence diploid cells skip meiosis I and execute meiosis II divi

160 Finally, we report that diploid cells starved for glucose also initiate the fila

161 hat the poliovaccine was passaged in a human diploid cell strain.

162 Overexpression of cyclin D2 in diploid cells strongly potentiated the ability to prolif

163 of G1 to S phase transition in normal human diploid cells such as WI38, suggesting that the genetic

164 ice was able to yield HCCs composed of small diploid cells, suggesting that initiated cells are gener

165 d version of the E subunit from heterozygous diploid cells, suggesting that more than one E subunit i

166 i5 activator protein is not bound to URS1 in diploid cells, suggesting that recruitment of the Tup1-C

167 e give rise to teliospores, which are round, diploid cells surrounded by a specialized cell wall.

168 acts were more stable in the mitochondria of diploid cells than in haploids.

169 lves the fusion of haploid gametes to form a diploid cell that subsequently undergoes meiosis to gene

170 otype will surpass the viability of a normal diploid cell, the evolution of a neoplastic cell species

171 In diploid cells, the a1-alpha2 complex represses the trans

172 ng the proliferation and senescence of human diploid cells through a ROS signaling pathway.

173 defects in late anaphase and cytokinesis in diploid cells; thus one hypothesis is that the expressio

174 esponse, promoting the transition of the new diploid cell to vegetative growth.

175 RC) protein Cdc6 causes human nontransformed diploid cells to arrest nonlethally in G1-G1/S and S pha

176 ivision that halves the genetic component of diploid cells to form gametes or spores.

177 essential because they are better able than diploid cells to mechanically stabilize wounds, especial

178 Normal human diploid cells transiently expressing hTRT possessed telo

179 Rst1 and Rst2 are necessary for the a/alpha diploid cell type.

180 there are similarities between haploids and diploids, cell type-specific differences clearly alter t

181 thout perturbing cell proliferation in other diploid cell types.

182 iable haploid state that can be derived from diploid cells under in vitro and in vivo conditions, and

183 oublings (PDs), cultures of normal mammalian diploid cells undergo an irreversible growth arrest know

184 During meiosis, a diploid cell undergoes two rounds of nuclear division fo

185 -labeled cells showed that the percentage of diploid cells undergoing DNA synthesis, the progression

186 yces pombe mei3(+) gene is expressed only in diploid cells undergoing meiosis.

187 virus standard rabies virus, or with a human diploid cell vaccine (HDCV).

188 paired in vegetatively growing budding yeast diploid cells, via multiple interstitial interactions, a

189 directs bud emergence to the distal pole of diploid cells, was localized to the distal pole of haplo

190 hat proteins required for bipolar budding in diploid cells were required for haploid invasive growth.

191 ociation with pericentric heterochromatin in diploid cells, where it appears to have roles in chromos

192 Overexpression of FLO11 in diploid cells, which are otherwise not invasive, enables

193 In heterozygous diploid cells, wild-type Pol-gamma suppresses mutation-a

194 sizes in different model systems, including diploid cells with a chromosomal breakpoint that has bee

195 Diploid cells with a single copy of NDC1 can survive by

196 n with the homologous chromosome, whereas in diploid cells with an alpha mating type (matDelta/MATalp