ライフサイエンスコーパス: dipolar coupling

1 ts of local backbone structure (NMR residual dipolar couplings).

2 on despite having a larger cross-section for dipolar coupling.

3 is obtained from the presence of the 13C-14N dipolar coupling.

4 e analyzed in terms of the DQ relaxation and dipolar coupling.

5 at approximately 165 ppm and lacks (15)N for dipolar coupling.

6 dipolar coupling, and solution NMR residual dipolar coupling.

7 et of experimental NMR methyl group residual dipolar couplings.

8 , as manifested by their strong (19)F-(29)Si dipolar couplings.

9 s constraints, including the methyl residual dipolar couplings.

10 uring NMR relaxation parameters and residual dipolar couplings.

11 tive magnitude of the respective (15)N-(17)O dipolar couplings.

12 l shifts as well as (1)H-(15)N heteronuclear dipolar couplings.

13 using NMR spectroscopy by employing residual dipolar couplings.

14 tra suitable for the measurement of residual dipolar couplings.

15 lies on the basis of statistical analysis of dipolar couplings.

16 ct 1JCalphaC' scalar and 1DCalphaC' residual dipolar couplings.

17 nd accurately measure numerous heteronuclear dipolar couplings.

18 13C and 15N) and refinement against residual dipolar couplings.

19 by complete cross-validation of the residual dipolar couplings.

20 aints in the form of backbone (15)N residual dipolar couplings.

21 x orientations were determined from residual dipolar couplings.

22 ear Overhauser enhancement data and residual dipolar couplings.

23 aeolicus LpxC-TU-514 complex using residual dipolar couplings.

24 -(1)H(N) as well as (13)C(alpha)-(1)H(alpha) dipolar couplings.

25 otope-filtered NMR experiments, and residual dipolar couplings.

26 using NMR order tensor analysis of residual dipolar couplings.

27 rder parameters from the (13)C-(1)H residual dipolar couplings.

28 AF) allowed us to measure 86 N-H(N) residual dipolar couplings.

29 ion of holo-ACPP to ACPS by fitting residual dipolar couplings.

30 Residual dipolar couplings ( (1) D HN and (1) D CalphaHalpha) ind

31 ed via 2H quadrupolar couplings, C-H and N-H dipolar couplings, 13C chemical shift anisotropies, and

32 hemical shifts are encoded by the (1)H-(15)N dipolar couplings, 2D dipolar-encoded HETCOR (i.e., de-H

33 The measured 1H-15N residual dipolar coupling agrees with the atomic coordinates from

34 Residual dipolar couplings allowed not only the identification of

35 easurement of a broad range of heteronuclear dipolar couplings, allowing for a complete mapping of pr

36 Dipolar coupling also dominates for the axial boron atom

37 emical shift analysis, backbone N-H residual dipolar couplings, amide proton NOEs, and R(2) relaxatio

38 Six dipolar couplings among five resolved (13)C-labeled atom

39 Dipolar coupling analysis indicates that for most of the

40 Our residual dipolar coupling analysis reveals nonrandom conformation

41 According to residual dipolar coupling analysis, the gross structures of the A

42 Using the solution NMR methods of residual dipolar coupling analysis, we determine that significant

43 sive set of hetero- and homonuclear residual dipolar coupling and 31P chemical shift anisotropy restr

44 utilize the PISEMA pulse sequence to measure dipolar coupling and chemical shift, the two key paramet

45 ngle, small-angle X-ray scattering, residual dipolar coupling and inter-domain NOE nuclear Overhauser

46 r of RNA elements was determined by residual dipolar coupling and paramagnetic relaxation experiments

47 ed in aqueous solution by using NMR residual dipolar coupling and spin labeling methods and is based

48 stants are proportional to the square of the dipolar coupling and the spectral overlap integral betwe

49 se of the 19F spin increases the homonuclear dipolar coupling and thus the distance reach.

50 Cross validation against both the dipolar coupling and X-ray scattering data suggests that

51 upolar splittings together with (1)(5)N/(1)H dipolar couplings and (1)(5)N chemical shifts, using two

52 d with measurements of long-range (1)H-(13)C dipolar couplings and (13)C relaxation times.

53 Structural refinement of (1)H-(15)N dipolar couplings and (15)N chemical shifts measured by

54 NMR data including residual dipolar couplings and (15)N relaxation data demonstrated

55 surement of previously inaccessible residual dipolar couplings and (15)N relaxation parameters.

56 ndent 13C and 15N spectra, 13C-1H and 15N-1H dipolar couplings and 1H rotating-frame spin-lattice rel

57 easily acquired NMR data, including residual dipolar couplings and amide proton exchange rates.

58 ing an extensive set of restraints including dipolar couplings and backbone torsion angles.

59 loyed oriented solid-state NMR data, such as dipolar couplings and chemical shift anisotropy measured

60 NMR observables such as dipolar couplings and chemical shift anisotropy, which a

61 culated by linear regression of the residual dipolar couplings and chemical shifts at increasing alig

62 h distance- and mobility-dependent (1)H-(1)H dipolar couplings and detecting it through polysaccharid

63 ta on the two proteins derived from residual dipolar couplings and distance restraints from site-spec

64 istic APP-TM population observed by residual dipolar couplings and double electron-electron resonance

65 parable accuracy in back-calculated residual dipolar couplings and J-couplings across hydrogen bonds

66 troscopy, including measurements of residual dipolar couplings and molecular dynamics simulations, to

67 n excellent agreement with measured residual dipolar couplings and order parameter S(2).

68 Compared to residual dipolar couplings and PRE, modulation of the helical pro

69 Residual dipolar couplings and residual chemical shift anisotropy

70 e revealed by distance-dependent (13)C-(13)C dipolar couplings and spin diffusion.

71 segment (P2a.1-J2a.1 refined using residual dipolar couplings and the modeling program MC-Sym) we ha

72 nnealing driven by experimental NMR residual dipolar couplings and X-ray scattering data.

73 in, and distance, hydrogen bonding, residual dipolar coupling, and dihedral angle constraints were us

74 recently measured chemical shift anisotropy, dipolar coupling, and residual dipolar coupling data.

75 olid-state NMR chemical shift anisotropy and dipolar coupling, and solution NMR residual dipolar coup

76 equence was used to measure the internuclear dipolar coupling, and the results demonstrate (1) the me

77 (3)JH(N)H(alpha) scalar couplings, residual dipolar couplings, and (1)H-(15)N NOEs, we have optimize

78 rporating backbone chemical shifts, residual dipolar couplings, and amide proton distances into the R

79 to <S(2)NH(jump)> derived from the residual dipolar couplings, and an axially symmetric order parame

80 d peptide would be evident in local residual dipolar couplings, and possibly differences in homonucle

81 spectroscopy using chemical shifts, residual dipolar couplings, and spin relaxation.

82 the measurement of long-range heteronuclear dipolar couplings, and that they provide inaccurate valu

83 order parameters are based on heteronuclear dipolar couplings, and they are correlated to assigned c

84 However, in these experiments, all weak dipolar couplings are suppressed.

85 Residual dipolar couplings are used in a new way for residue sele

86 ether with spectroscopic selections based on dipolar couplings as well as two-dimensional spin-diffus

87 By measuring (1)H-(15)N dipolar-coupling as well as (15)N R1 and R1rho relaxatio

88 ed additional structural information through dipolar couplings, as follows: (1) to the nearest proton

89 Based on intermolecular dipolar coupling at positions 26, 44, and 64, these seco

90 A residual-dipolar-coupling-based refinement approach can be used t

91 The 700 Hz dipolar coupling between (13)C(alpha) and its directly b

92 gnetic behavior by effective lowering of the dipolar coupling between particles.

93 Dipolar coupling between spin labels across the dimer re

94 duced changes in distance as measured by the dipolar coupling between spin labels introduced onto the

95 owerful structural biology tool in which the dipolar coupling between two unpaired electron spins (si

96 tional resonance SSNMR measurements of (13)C dipolar couplings between backbone F23 and I26 of hIAPP

97 s to accurately measure strong heteronuclear dipolar couplings between directly bonded nuclei.

98 fsets of 13C carbonyl resonances and 13C-13C dipolar couplings between the labeled methyl and carbony

99 Averaging of the homonuclear (13)C/(13)C dipolar couplings, by MAS of the sample, enables the use

100 lution due to the efficient averaging of the dipolar couplings can be attained at MAS frequencies of

101 er alignment media, but the magnitude of the dipolar couplings can be easily scaled up by increasing

102 On the other hand, weak heteronuclear dipolar couplings can be measured using laboratory-frame

103 unction with other NMR experiments, residual dipolar couplings can provide valuable insights into the

104 We used NMR residual dipolar couplings, carbon spin relaxation (R(1) and R(2)

105 izing orientational restraints from residual dipolar couplings collected on solution NMR samples is p

106 NMR residual dipolar couplings confirm the crystal structures to be a

107 The value of the dipolar coupling constant, 5250 +/- 90 Hz, corresponds t

108 e resolved and well simulated using distinct dipolar coupling constants DCalphaH and DCalphaD for the

109 specific (1)H-(13)C/(1)H-(15)N heteronuclear dipolar coupling constants for CAP-Gly and CTD CA, repor

110 one-shot determination of accurate residual dipolar coupling constants from a single NMR spectrum.

111 e a helical structure that predicts residual dipolar coupling constants that are incompatible with th

112 0 experimental nuclear Overhauser effect and dipolar coupling constraints ( approximately 17 constrai

113 The residual dipolar coupling data and NMR chemical shift data sugges

114 mall angle X-ray scattering and NMR residual dipolar coupling data demonstrates unambiguously that th

115 -H, N-C', Calpha-Halpha, Calpha-C') residual dipolar coupling data in five independent alignment medi

116 d diubiquitin, characterized by the residual dipolar coupling data measured at several pH conditions.

117 NMR chemical shifts and residual dipolar coupling data reveal Ca(2+)-dependent difference

118 al contributions; when coupled with residual dipolar coupling data, a KGSrna ensemble revealed a prev

119 The collection of residual dipolar coupling data, amide protection factors, and par

120 present NMR resonance assignments, residual dipolar coupling data, functional analysis, and a struct

121 As judged from the dipolar coupling data, the remainder of the structure is

122 using nuclear Overhauser effect and residual dipolar coupling data.

123 t anisotropy, dipolar coupling, and residual dipolar coupling data.

124 NMR dipolar couplings (DCs) depend intrinsically on both mol

125 e difference between two successive residual dipolar couplings (DeltaRDCs) involving C6/8-H6/8, C3'-H

126 tein, the magnitude and sign of the residual dipolar couplings depend on the orientation of each bond

127 Through measurements of dipolar-coupling derived order parameters of bond motion

128 agreement with (+/-20%) the root-sum-squared dipolar couplings determined from the crystal structure.

129 ttering, nuclear magnetic resonance residual dipolar couplings, dipolar electron-electron resonance s

130 ng 2D NMR NOESY, ROESY, T-ROESY and residual dipolar coupling experiments in a range of solvents, alo

131 (13)C relaxation and residual dipolar coupling experiments revealed interhelical flexi

132 MR chemical shift perturbation, and residual dipolar coupling experiments support the idea that the d

133 and (13)C-(1)H, (15)N-(1)H, and (13)C-(15)N dipolar couplings for all labeled residues.

134 Measurement of residual dipolar couplings for membrane proteins will dramaticall

135 shifts and paramagnetically induced residual dipolar couplings for six different lanthanide ions.

136 Measuring residual dipolar couplings for the different bound states clearly

137 Measurements of (1)H-(13)C dipolar couplings for the two species of Ala-PLB showed

138 chemical shift and (1)H-(15)N heteronuclear dipolar coupling frequencies as orientation constraints

139 ependent (15)N chemical shift and (1)H-(15)N dipolar coupling frequencies.

140 omain walls, but their density is limited by dipolar coupling from their fringing magnetic fields.

141 somers to deconvolve the influence of SAM-LC dipolar coupling from variations in molecular geometry,

142 ited not only from the inclusion of residual dipolar couplings from partially aligned samples but als

143 hyperpolarized LLS, induced by heteronuclear dipolar couplings, generates strongly enhanced antiphase

144 5)N chemical shift anisotropy and (1)H/(15)N dipolar couplings have been analyzed using short-time av

145 of a large set of protein backbone one-bond dipolar couplings have been carried out to refine the st

146 erived data (relaxation parameters, residual dipolar couplings, hydrogen exchange rates, pK(a) values

147 Backbone amide chemical shifts, residual dipolar couplings, hydrogen-deuterium exchange, and (15)

148 nst the (13)C(alpha)-(13)C' and (13)C'-(15)N dipolar couplings improves the agreement between experim

149 gree of headgroup mobility that averages the dipolar coupling in the liquid crystalline phase.

150 sample was determined by measuring the 15N-H dipolar coupling in the triflic acid salt of the complet

151 ment media and N-C', H(N)-C', and C alpha-C' dipolar coupling in two alignment media can be accounted

152 We show that N-H dipolar couplings in 11 different alignment media and N-

153 ial buildup (DeltaS/S < 0.2) yield effective dipolar couplings in agreement with (+/-20%) the root-su

154 clude the measurement of (1)H-(13)C residual dipolar couplings in Ala(beta) methyls, characterization

155 in leads to a change in sign of the residual dipolar couplings in local regions of the polypeptide; t

156 landscape of the complex using NMR residual dipolar couplings in replica-averaged metadynamics simul

157 tion was made possible by measuring residual dipolar couplings in weakly oriented micelle samples of

158 Finally, distributions of residual dipolar couplings indicate that the two domains tumble a

159 Measurements of C-H and N-H dipolar couplings indicate that, on the sub-microsecond

160 ly align the water dipoles, nearest-neighbor dipolar coupling interactions, and Coulombic repulsion.

161 ulation of helix estimated from the residual dipolar couplings is in excellent agreement with that de

162 al transition moment and the axis of maximum dipolar coupling, is also confirmed by magnetophotoselec

163 n arranged in such a way that their in-phase dipolar coupling leads to a collective excitation of the

164 The interchain (13)C-(19)F dipolar coupling measured in a rotational-echo double-re

165 w that 15N chemical shift anisotropy and N-H dipolar coupling measured on these powder samples can be

166 Furthermore, residual dipolar couplings measured for MBD3 bound to methylated

167 fragments that are consistent with multiple dipolar couplings measured in a single alignment medium

168 teronuclear relaxation experiments, residual dipolar coupling measurements and analytical ultracentri

169 Spin-spin dipolar coupling measurements confirmed that in the nano

170 NMR analysis and residual dipolar coupling measurements indicate that the isolated

171 Residual dipolar coupling measurements indicate that the structur

172 NMR carbon spin relaxation data and residual dipolar coupling measurements reveal a flexible yet stac

173 roximity between V3 and K17, and (13)C-(13)C dipolar coupling measurements reveal proximity between t

174 ve to the unphosphorylated complex, residual dipolar coupling measurements reveal that the structures

175 Residual dipolar coupling measurements, however, demonstrate unam

176 S(2) order parameters derived from residual dipolar coupling measurements.

177 troscopy, supplemented by extensive residual dipolar coupling measurements.

178 ng chemical shift perturbations and residual dipolar coupling measurements.

179 asis of this information and of NMR residual dipolar couplings measurements.

180 Residual dipolar coupling methods have revealed the presence of e

181 rge g-anisotropy is shown to result in large dipolar couplings near g( parallel) and uniquely anisotr

182 infer that water exhibits distinct (1)H-(1)H dipolar coupling networks with the backbone and side-cha

183 h measurements of intermolecular (13)C-(13)C dipolar couplings observed in PITHIRDS-CT experiments.

184 teraction strength, we elucidate the role of dipolar coupling of molecular monolayers to their enviro

185 Residual dipolar coupling of partially aligned protein and the NM

186 ), the close to zero values for the residual dipolar couplings of the backbone amides, and minimal de

187 15)N spin relaxation and (15)N,(1)H residual dipolar couplings of the covalent ChVLig-AMP intermediat

188 veal enantiotopic recognition using residual dipolar couplings or to determine the absolute configura

189 sites based on either spatial proximity (via dipolar couplings) or through-bond connectivity (via sca

190 his study is in good agreement with residual dipolar coupling, paramagnetic resonance enhancement, sm

191 NMR residual dipolar coupling (RDC) analysis of GGC in a DNA-origami

192 rget site have been investigated by residual dipolar coupling (RDC) and paramagnetic relaxation enhan

193 -coupling((3)J(H(N))(H(alpha))) and residual dipolar coupling (RDC) data calculated from the REMD tra

194 to best reproduce the experimental residual dipolar coupling (RDC) data for this system, as both che

195 only unassigned chemical shifts and residual dipolar coupling (RDC) data.We introduce a geometric opt

196 -D exchange, backbone dynamics, and residual dipolar coupling (RDC) experiments reveal regions of fle

197 g internal from overall motions and residual dipolar coupling (RDC) measurements for determining the

198 also supported by the results from residual dipolar coupling (RDC) measurements obtained using Pf1-p

199 on CEACAM1-IgV dimerization and use residual dipolar coupling (RDC) measurements to characterize the

200 k alignment of soluble proteins for residual dipolar coupling (RDC) measurements.

201 l hexaphosphate (IHP), using 15N-1H residual dipolar coupling (RDC) measurements.

202 dynamics (MD) trajectories and NMR residual dipolar coupling (RDC) measurements.

203 We have applied the residual dipolar coupling (RDC) method to investigate the solutio

204 ow the plasticity in the model-free residual dipolar coupling (RDC) order parameters and in an ensemb

205 ports the acquisition of (1)H-(15)N residual dipolar coupling (RDC) values for individual subunits in

206 The residual dipolar coupling (RDC) values of the two tripeptide unit

207 nd complexed to HPr), combined with residual dipolar coupling (RDC), small- (SAXS) and wide- (WAXS) a

208 me P450(cam) (CYP101) obtained from residual dipolar coupling (RDC)-restrained molecular dynamics (MD

209 ethodology that simultaneously uses residual dipolar couplings (RDC) and the small-angle X-ray scatte

210 dynamics (MD) simulations with NMR residual dipolar couplings (RDC) measured in elongated RNA.

211 , is known from an extensive set of residual dipolar couplings (RDC), previously used to refine its s

212 Using NMR residual dipolar coupling (RDCs), we characterized Na+-induced ch

213 n of orientational constraints from residual dipolar couplings (RDCs) and chemical shift anisotropy (

214 spectroscopy (NOESY) spectroscopy, residual dipolar couplings (RDCs) and paramagnetic relaxation enh

215 ntation restraints derived from NMR residual dipolar couplings (RDCs) and semiquantitative distance r

216 a combination of a large number of residual dipolar couplings (RDCs) and trans-hydrogen bond NMR met

217 NMR residual dipolar couplings (RDCs) are exquisite probes of protein

218 Residual dipolar couplings (RDCs) are important probes in structu

219 Residual Dipolar Couplings (RDCs) are integral to the refinement

220 Residual dipolar couplings (RDCs) can provide a means of assignin

221 NMR residual dipolar couplings (RDCs) carry rich dynamics information

222 of the 70-residue protein eglin C, residual dipolar couplings (RDCs) for HN-N and HA-CA bond vectors

223 tural abundance one-bond (1)H-(13)C residual dipolar couplings (RDCs) for menthol measured in the gel

224 Alternatively, one can measure residual dipolar couplings (RDCs) for natural abundance lipid sam

225 ents and the experimentally derived residual dipolar couplings (RDCs) for the complex.

226 measurement of backbone (1)H-(15)N residual dipolar couplings (RDCs) from samples of two different c

227 re multiple independent sets of NMR residual dipolar couplings (RDCs) has made it possible to charact

228 Residual Dipolar Couplings (RDCs) have emerged in the past two de

229 xperiment was applied for measuring residual dipolar couplings (RDCs) in an 8 kDa protein Z-domain al

230 The invariance of NMR residual dipolar couplings (RDCs) in denatured forms of staphyloc

231 proach based on measurement of many residual dipolar couplings (RDCs) in differentially orienting aqu

232 Residual dipolar couplings (RDCs) measured for internally rigid m

233 High precision residual dipolar couplings (RDCs) measured for the backbone (1)H-

234 S data, supplemented by NMR-derived residual dipolar couplings (RDCs) measured in a weakly aligning m

235 However, NMR residual dipolar couplings (RDCs) measured under three different

236 tes between dipolar interactions to residual dipolar couplings (RDCs) of individual consecutive H(N)-

237 rs such as chemical shifts (CSs) or residual dipolar couplings (RDCs) on structural propensity are kn

238 In principle, residual dipolar couplings (RDCs) provide a useful complement to

239 Analysis of residual dipolar couplings (RDCs) shows that binding of MalF-P2 i

240 Residual dipolar couplings (RDCs) were measured for (15)N-(1)H am

241 domain orientation restraints from residual dipolar couplings (RDCs) without a need for a previously

242 Y spectrum revealed many long-range residual dipolar couplings (RDCs), and detailed analysis of magne

243 , as mapped by NMR spin relaxation, residual dipolar couplings (RDCs), and scalar couplings, illustra

244 Residual dipolar couplings (RDCs), commonly measured for biologic

245 Residual dipolar couplings (RDCs), in combination with molecular

246 The use of NMR-derived residual dipolar couplings (RDCs), in magnetically aligned media,

247 entional 1D and 2D NMR spectra, and residual dipolar couplings (RDCs), is reported.

248 EST) NMR spectroscopy for measuring residual dipolar couplings (RDCs), which provide unique long-rang

249 tively with NMR chemical shifts and residual dipolar couplings (RDCs).

250 ally enriched RNA samples using NMR residual dipolar couplings (RDCs).

251 other, using 'relativistic' sets of residual dipolar couplings (RDCs).

252 can be achieved by refinement with residual dipolar couplings (RDCs).

253 a SMM with the evaluation of large residual dipolar couplings (RDCs).

254 oyed relies principally on backbone residual dipolar couplings recorded in three different alignment

255 bin can also explain the pattern of residual dipolar couplings reported previously for denatured stat

256 many of the analogous amides in the residual dipolar coupling-restrained ubiquitin ensemble are subst

257 hydrogen bond constraints, and 362 residual dipolar coupling restraints derived from a series of two

258 , a nearly complete set of backbone residual dipolar coupling restraints was recorded for the fusion

259 60-kDa protein has been built using residual dipolar coupling restraints.

260 alone, but the addition of NMR RDC (residual dipolar coupling) restraints improves the structure mode

261 The direction of maximum dipolar coupling shifts from the out-of-plane direction

262 did not result in a loss of the (13)C-(13)C dipolar couplings, showing that these couplings are prim

263 Analysis of NMR residual dipolar couplings shows that CBD12 assumes on average an

264 ased on NOE distance restraints and residual dipolar couplings, shows that the NHR and CHR helices re

265 our unfolded ensemble dominate the residual dipolar coupling signal, whereas the uniformity of the s

266 f scalar couplings and additional long-range dipolar couplings significantly enhances signal to noise

267 olution NMR study of unbound Ly49A, aided by dipolar coupling technology.

268 he basis of a very extensive set of residual dipolar couplings, than for any single static NMR struct

269 -sweep spectra show evidence of intercluster dipolar coupling that can be simulated using an uncouple

270 Many of these same residues have residual dipolar couplings that deviate from structural predictio

271 r ensemble consistent with measured residual dipolar couplings that revealed dynamic motions up to mi

272 iment DROSS, we resolved (13)C-(1)H residual dipolar couplings that were interpreted with a statistic

273 ha, HN-N, and Calpha-C' J-modulated residual dipolar couplings, the backbone rmsd improves to 0.22 A.

274 By examining the (13)C-(14)N dipolar coupling through low-field (B0 = 3 T) (13)C{(1)H

275 Dipolar coupling to additional peptides is weaker than t

276 f water protons through their time-dependent dipolar coupling to paramagnetic probes, here nitroxide

277 ulations on Cu(phacac)(2), indicate enhanced dipolar coupling to the d(xz) --> d(xy) transition of th

278 transfer (DREPT), allows for a wide range of dipolar couplings to be encoded, providing high resoluti

279 We obtained these results by using residual dipolar couplings to characterize the dynamics of ubiqui

280 ly improves the fit of experimental residual dipolar couplings to structural coordinates.

281 13)C chemical shifts and (13)C-(1)H residual dipolar couplings under magic-angle spinning.

282 the issue, we have measured the NMR residual dipolar couplings using alignment media of stretched gel

283 ng chemical shift perturbations and residual dipolar couplings was employed to obtain a structural mo

284 agnetic relaxation enhancement, and residual dipolar couplings, we have characterized structural and

285 Using residual dipolar couplings, we show that the four structural unit

286 filamentous phage liquid crystalline media, dipolar couplings were also measured when the protein wa

287 Large, well-resolved (1)H and (11)B dipolar couplings were also observed.

288 rotational Overhauser effects, and residual dipolar couplings were constructed.

289 Data from NMR chemical shifts and residual dipolar couplings were used to guide the construction of

290 Backbone residual dipolar couplings were used to provide long range orient

291 NMR chemical shift data and residual dipolar couplings were used to show that the local secon

292 e experimental data afforded by NMR residual dipolar couplings (which yield both orientational and sh

293 s alignment-inducing agents to gain residual dipolar couplings, which are valuable restraints for mac

294 c relaxation enhancements (PRE) and residual dipolar couplings, which reveal an additional long-range

295 lations with various data sets indicate that dipolar couplings will be critical for obtaining accurat

296 al field spectroscopy correlating (15)N-(1)H dipolar coupling with (15)N chemical shift to determine

297 SR) signal of N@C(60) through intramolecular dipolar coupling with a strength of 27.0 MHz.

298 paring calculated (1)H-(13)C methyl residual dipolar couplings with measured values, and the level of

299 Measurement of (19)F-(19)F dipolar couplings within each CF(3) moiety revealed that

300 ant correlation was found, with both sets of dipolar couplings yielding a correlation coefficient of