ライフサイエンスコーパス: dipyrromethane

1 ied to a bis(dipyrromethane) and a porphyrin-dipyrromethane.

2 a 1-acyldipyrromethane in the presence of a dipyrromethane.

3 the availability of multigram quantities of dipyrromethanes.

4 the availability of multigram quantities of dipyrromethanes.

5 , and trace scrambling for alkyl-substituted dipyrromethanes.

6 The syntheses employ dipyrromethanes, 1-acyldipyrromethanes, and 1,9-diacyldi

7 dehyde followed by hydrodesulfurization gave dipyrromethane-1,9-(13)C, which upon condensation with a

8 at the 5-position or carbinol position, or a dipyrromethane-1,9-dicarbinol bearing an acetal group at

9 ne-1,9-(13)C, which upon condensation with a dipyrromethane-1,9-dicarbinol bearing three pentafluorop

10 es of the existing "2 + 2" (dipyrromethane + dipyrromethane-1,9-dicarbinol) method, such as absence o

11 of a 1-acyldipyrromethane and a 9-protected dipyrromethane-1-carbinol (derived from a 9-protected 1-

12 bearing an acetal group at the 5-position, a dipyrromethane-1-carbinol bearing an acetal group at the

13 reaction of a 1,9-diacyldipyrromethane and a dipyrromethane also gives the palladium porphyrin.

14 alkylboron motif bound to the pyrrole of the dipyrromethane and coordinated to the imidazole imino ni

15 with the anticipated nucleophilicity of the dipyrromethane and dipyrromethanemonocarbinol precursors

16 1-(p-Bromophenyl)nitrosoethylene reacts with dipyrromethanes and pyrrole to afford two isomeric oxime

17 by [2 + 2] condensation of the corresponding dipyrromethanes and subsequent oxidative aromatization.

18 plexation strategy has been applied to a bis(dipyrromethane) and a porphyrin-dipyrromethane.

19 able scrambling (LD-MS) for aryl-substituted dipyrromethanes, and trace scrambling for alkyl-substitu

20 a new method for effecting the oxidation of dipyrromethane-based macrocycles in organic solvents has

21 The condensation of an aldehyde with a dipyrromethane bearing a sterically unhindered aryl subs

22 eso-formyl substituents entails the use of a dipyrromethane bearing an acetal group at the 5-position

23 by preparing multigram quantities of diacyl dipyrromethanes bearing a variety of substituents.

24 substituted bis-formyldihydrodipyrrins 6 and dipyrromethane bis-carboxylic acids 7 in 5% TFA/CH2Cl2 (

25 eport here a neural stem cell specific boron-dipyrromethane (BODIPY) derivative compound of designati

26 aride (LPS) fluorescently labeled with boron dipyrromethane (BODIPY) first binds to the plasma membra

27 ertrade mark Red DND-99, DiOC6(3), and boron dipyrromethane (BODIPY)-ceramide, respectively.

28 The latter approach makes use of dipyrromethane building blocks bearing mono or tripodal

29 NaBH(4), acid-catalyzed condensation with a dipyrromethane, DDQ oxidation) afforded the desired free

30 )dipyrromethane or via presynthesis of a bis(dipyrromethane) derivative 22 (from bisnaphthaldehyde 12

31 esults in the formation of 5-alkoxy-5-phenyl dipyrromethane derivatives, which function as ready prec

32 rodipyrrins 9 with symmetrically substituted dipyrromethane diacids 10 (Method I).

33 nvolves the acid-catalyzed condensation of a dipyrromethane-dicarbinol and a dipyrromethane followed

34 e diacyl dipyrromethane to the corresponding dipyrromethane-dicarbinol is achieved with NaBH(4) in me

35 desirable features of the existing "2 + 2" (dipyrromethane + dipyrromethane-1,9-dicarbinol) method,

36 Two dipyrromethane + dipyrromethanedicarbinol routes to a me

37 tuents were prepared in yields of 24-49% via dipyrromethane + dipyrromethanedicarbinol routes, and th

38 Two complementary dipyrromethane + dipyrromethanemonocarbinol routes to a

39 olar nature of such doubly masked imidazolyl-dipyrromethanes facilitated handling.

40 We have generated a set of BODIPY (boron dipyrromethane) fluorophores, including one that is intr

41 nsation of a dipyrromethane-dicarbinol and a dipyrromethane followed by oxidation with DDQ.

42 acylation and bromination of a 5-substituted dipyrromethane followed by reduction.

43 , 4-, and 5-positions and the application to dipyrromethane formation.

44 for the preparation of unsymmetrical diacyl dipyrromethanes has been developed that involves (1) mon

45 roperties of a series of 2,6-diamidopyridine dipyrromethane hybrid macrocycles is presented.

46 preparation of a set of 15 diverse monoacyl dipyrromethanes in good yield at the multigram scale.

47 Other reactions of the 1,9-bis(RS)dipyrromethane include oxidation to give (i) the 1,9-bis

48 d by geminal substitution aromatization to a dipyrromethane is a competing side reaction.

49 ransition metal complexes (Mn --> Zn) of the dipyrromethane ligand, 1,9-dimesityl-5,5-dimethyldipyrro

50 The precursors include dipyrromethanes, monoacyldipyrromethanes, and diacyldipy

51 been developed to two beta-substituted bromo-dipyrromethane monocarbinols (Eastern halves).

52 examined for the direct 1,9-diacylation of a dipyrromethane or the 9-acylation of a 1-acyldipyrrometh

53 be achieved by employing (pentafluorophenyl)dipyrromethane or via presynthesis of a bis(dipyrrometha

54 rins, obtained in three steps from a 5-(aryl)dipyrromethane precursor, display remarkable features: (

55 The reactivity of nitrosoalkenes toward dipyrromethanes, pyrrole, and 2,5-dimethylpyrrole is des

56 er with readily available 5-aryl-substituted dipyrromethanes such as 5-mesityldipyrromethane to affor

57 The dipyrromethane synthesis was carried out using a 2:1 rat

58 The reaction is selective for dipyrromethanes that bear acyl groups at both the 1- and

59 A reliable means for converting a dipyrromethane to a 1-acyldipyrromethane-dialkylboron co

60 pyridyl thioester, reduction of the monoacyl dipyrromethane to the corresponding carbinol, and self-c

61 Reduction of the diacyl dipyrromethane to the corresponding dipyrromethane-dicar

62 The acylation of dipyrromethanes to form 1,9-diacyldipyrromethanes is an

63 hoxyphenylmethanol) with different meso-aryl dipyrromethanes under mild acid-catalyzed conditions.

64 A procedure for the diacylation of dipyrromethanes using EtMgBr and an acid chloride has be

65 Selected masked dipyrromethanes were characterized by (11)B and (15)N NM

66 Six meso-substituted dipyrromethanes were prepared by the reaction of 2-(n-de

67 1,9-bis(RS)dipyrrin or (ii) the 1,9-bis(RSO2)dipyrromethane, which underwent subsequent complexation

68 n good yields from a one-pot condensation of dipyrromethane with the aldehyde of a xanthene spacer fo

69 involves the selective monoacylation of the dipyrromethanes with a pyridyl thioester, reduction of t

70 tion of readily available 5-aryl-substituted dipyrromethanes with acenaphthenequinone leads to the tr