ライフサイエンスコーパス: direct link

1 Investigating direct links across phenotypic hierarchies is fraught wi

2 ation and lung metastasis, consistent with a direct link among invadopodia, ECM degradation, and meta

3 In summary, our results reveal a direct link among TTP, IFN-gamma, and IL-23, indicating

4 ligase-mediated HPK1 degradation revealed a direct link and novel role of CUL7/Fbxw8 ubiquitin ligas

5 d by heavy isotope labeling, demonstrating a direct link between (promoting) vibrations in the protei

6 susceptibility to E. paraensei, providing a direct link between a gastropod immune molecule and resi

7 n at the transcription level, indicating the direct link between a nuclear receptor and the PI3K/AKT

8 observed link with mTOR activity suggests a direct link between a robust biomarker of healthy neurom

9 s is the first in-vivo study demonstrating a direct link between a structural abnormality of pulmonar

10 arboxylic acid cycle intermediate provides a direct link between aerobic metabolism and bacterial str

11 not alter MOR mRNA expression, suggesting no direct link between agonist treatment and MOR gene trans

12 n Akt-dependent manner and provide the first direct link between Akt and the regulation of IRES activ

13 Taken together, these results uncover a direct link between ALK1 and Notch signaling during vasc

14 ncoding key metabolic enzymes has provided a direct link between altered metabolism and cancer.

15 However, a direct link between alternative pre-mRNA splicing and sm

16 etween CSF Abeta levels and WM-LL suggests a direct link between amyloid pathology and WM macrostruct

17 These findings show a direct link between an intracellular GPCR and behavioura

18 present the first functional indication of a direct link between an NDM-linked activating mutation in

19 nsforming property of NPM/ALK and describe a direct link between an oncoprotein and an immunosuppress

20 akness and increased mortality, suggesting a direct link between anti-FHL1 responses and muscle damag

21 These results provide a direct link between APP and calcium signaling and might

22 Despite this, a direct link between ATF4 and the degree of proliferative

23 distance constraint model asserts there is a direct link between available degrees of freedom and coo

24 gene expression in developmental contexts, a direct link between B-type lamins and developmental gene

25 ntaining a single alkene side chain reveal a direct link between backbone rigidity and electron trans

26 for Ape1 in telomere protection, providing a direct link between base excision DNA repair activities

27 he calpain-2-PTPN13-c-Abl pathway provides a direct link between calpain-2 activation and abnormal ta

28 roles for CD4(+) T cells in CLL expansion, a direct link between CD38 expression by leukemic B cells

29 Together, these data reveal a direct link between cell signaling and Golgi architectur

30 ectional nuclear transport and demonstrate a direct link between cell-cycle machinery and dynein path

31 eneration, and spatial navigation, forging a direct link between cellular and systems neuroscience.

32 interference (RNAi) efficacy, establishing a direct link between cellular physiology and RNAi.

33 after colonization); this result provided a direct link between chitin utilization and symbiont pers

34 ation of sialoglycoproteins, demonstrating a direct link between cholesterol storage and abnormal rec

35 A direct link between cholinergic activity and complement

36 Our findings demonstrate the direct link between chromatin modification and higher-or

37 ding of rpS6 phospho-regulation and define a direct link between CK1 and translation initiation.

38 Together, our results confirm a direct link between cognitive performance and the dynami

39 However, a direct link between common genetic variation in DDC and

40 This provides a direct link between complex III as the main source of RO

41 horylation-independent signaling, implying a direct link between conformational behavior and the abil

42 However, a direct link between connectivity and recovery of genetic

43 e topography contributions, thus providing a direct link between contact line dynamics and roughness

44 Here, we report a direct link between Cox17, a protein involved in the ass

45 This finding postulates a direct link between CrPFO and hydrogenase and provides n

46 Together, our findings reveal a direct link between cyclin E and HIF-1 activities in mam

47 For the first time, a direct link between DAT availability and reward anticipa

48 Importantly, we demonstrated a direct link between DC dysfunction and impairments in CD

49 Taken together, we provide evidence for a direct link between developmental regulators, specific c

50 Further, we observe a direct link between disorder in one lattice modulation,

51 This demonstrates a direct link between disrupted attachment of myosin molec

52 Hence, we provide a direct link between DNA binding and the behaviour of Cbp

53 has been observed in the cell and provide a direct link between DNA methylation and the structure an

54 ir in response to DNA damage, thus drawing a direct link between DNA repair and cellular metabolism.

55 This mechanism thus provides a direct link between DNA synthesis and RNR regulation.

56 g of reward variability, thus establishing a direct link between dopamine and adaptation to reward va

57 Thus, our study provides a direct link between dynamic MTs and the postsynaptic str

58 Although no direct link between dystrophin and MTs has been document

59 following the Marinoan glaciation, or for a direct link between early animal evolution and redox con

60 itivity to per capita risk, providing a more direct link between empirical and theoretical studies wh

61 sed nitric oxide (NO(.)) production, but the direct link between endothelial dysfunction and aggravat

62 array of cichlid fish species, suggesting a direct link between environmental and evolutionary dynam

63 ore, measured alterations do not guarantee a direct link between enzyme and substrate.

64 ique function for RNF4, which may serve as a direct link between epigenetic DNA demethylation and DNA

65 surveyor of chromatin synthesis, providing a direct link between epigenetics and cell-cycle progressi

66 These results reveal an unanticipated direct link between ER homeostasis and the transcription

67 We show a direct link between Erbb2 activity and remodeling of myo

68 phorylated these sites in vitro, providing a direct link between ERK signaling and the transcriptiona

69 i-snRNP formation, our discovery points to a direct link between eviction-coupled erasure of the ubiq

70 Here we show a direct link between excess excitation energy and photoca

71 Our results provide a direct link between fate specification and morphogenetic

72 ilization of apo-ferrochelatase, providing a direct link between Fe-S biogenesis and completion of he

73 However, a direct link between FGF signaling and crystallin gene tr

74 Here, we present a direct link between GABA signaling and autistic perceptu

75 We observe a direct link between Galpha peptide binding and stabiliza

76 These data reveal a direct link between gastric filling with food and circad

77 gestational RA supplementation, supporting a direct link between GCN5, TACC1, and RA signaling in the

78 We found a direct link between gene triplication and defects in neu

79 Overall, these results define a direct link between genotoxic stress-activated c-Abl kin

80 illnesses such as schizophrenia, there is no direct link between genotype and phenotype.

81 d as if the task were to find a more or less direct link between genotypic and phenotypic levels, on

82 B-cell and myeloid development and provide a direct link between Gfi-1 and the B-cell transcriptional

83 Direct link between glutathione oxidation and copper com

84 the downstream molecules of HER2 pathway, no direct link between HER2 and NRF2 has ever been establis

85 their DNA helicase activity and establish a direct link between HIF-1 and the cell-cycle machinery.

86 chromatin within seconds, and demonstrate a direct link between higher-order chromatin structure and

87 cetyllysine-binding module and established a direct link between histone acetylation and DOT1L-mediat

88 nding module, thereby establishing the first direct link between histone methylation and the metazoan

89 indings reveal a previously unrecognized but direct link between HP1 and CPC localization in the cent

90 mory in the right amygdala, thereby making a direct link between human and animal research.

91 mTORC1 are only partially understood, and a direct link between hypoxia-driven physiological stress

92 These data provide the first evidence of a direct link between IDO1 expression and the oncogenic ac

93 s, PI3K/AKT/TOR, and MYC), eIF4F serves as a direct link between important steps in cancer developmen

94 fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging

95 o IL-17-mediated toxicity further suggests a direct link between inflammation and neurodegeneration i

96 lung disease, and we recently established a direct link between injury to the type II alveolar epith

97 Further, this report demonstrates a direct link between integrin alpha1beta1 function in ret

98 ies of human glioblastoma cells, providing a direct link between intracellular (and particularly nucl

99 We further discovered a direct link between intrinsic connectivity and gray matt

100 ropsychological models of OCD by providing a direct link between intrinsically abnormal functional co

101 ences the satiety hormone leptin; however, a direct link between iron and leptin has remained elusive

102 A direct link between IRX3 expression and regulation of bo

103 The data demonstrate a direct link between journey-dependent coding and memory

104 These findings establish a direct link between known temporal modulation tuning in

105 photoreceptor excited state, thus creating a direct link between lambda(max) and k.

106 To show a direct link between let-7 and IL-10, forced overexpressi

107 by mitochondrial depolarization, although a direct link between loss of mitochondrial membrane poten

108 duced GFI1 gene expression levels revealed a direct link between low GFI1 protein level and accelerat

109 concave trophic distribution implies a more direct link between lower and upper trophic levels, whic

110 These results imply a direct link between mammalian DNA replication, transcrip

111 These observations indicate a direct link between mass transfer from the subducted pla

112 a novel immune target of miR-10b, implying a direct link between metastasis capability and immune esc

113 Although a direct link between methamphetamine abuse and HIV-1 path

114 These results reveal a direct link between microsaccade production and the perc

115 our knowledge, our study provides the first direct link between microtubule defects and kinesin func

116 wing to its ability to provide a precise and direct link between microwave and optical frequencies.

117 Taken together, our results establish a direct link between misfolded mutant SOD1 and mitochondr

118 Our data thus establish a direct link between modification of epithelial polarity

119 Our findings establish a direct link between molecular function and the large-sca

120 sil data, and difficulties in establishing a direct link between morphological changes detectable in

121 nd the loss/reduction of adhesion suggests a direct link between morphology, biomechanics, and ecolog

122 The present data reveal the first direct link between mPT and seizure control, and provide

123 These results strongly support a direct link between mtDNA damage and cell cycle arrest.

124 Our findings show a direct link between mTORC1 and ERalpha, which further im

125 Presently, we have uncovered a direct link between mTORC1 and ERalpha.

126 ne expression and DNA methylation changes, a direct link between mutant DNMT3A, epigenetic changes an

127 ively, these findings provide evidence for a direct link between mutant Htt, mitochondrial dysfunctio

128 utations impede cargo transport, providing a direct link between neuroblastomas and neurodegeneration

129 n leukemia BM microenvironment illustrated a direct link between NF-kappaB activation and stromal-ass

130 This finding provides a direct link between NK-cell activation signals and KIR e

131 Thus, these results establish Dot6/Tod6 as a direct link between nutrient availability, Ribi gene reg

132 hip with weight gain; others have proposed a direct link between obesity and raised intracranial pres

133 The direct link between ONOO(-) and hyperalgesia was further

134 These results demonstrate a direct link between overproliferation and retinal dyspla

135 The results reveal a direct link between oxygenase catalysis and the regulati

136 on and proteasomal degradation and suggest a direct link between P450 phosphorylation, ubiquitination

137 e p53 regulatory network, miR-145 provides a direct link between p53 and c-Myc in this gene regulator

138 In this study, we identified a direct link between p53 function and MCT1 expression.

139 These data provide a direct link between pathology and mechanosensitive chann

140 explants from wild-type swine demonstrated a direct link between periciliary liquid (PCL) hydration a

141 ell type called the spore (sporulation), the direct link between PHB accumulation and efficiency of s

142 an development and behaviour and establish a direct link between Phf8 expression and serotonin signal

143 sed that YY1 is a phosphoprotein; however, a direct link between phosphorylation and the function of

144 iation of GR transactivation, establishing a direct link between Pin1 and the GR.

145 Our findings support a direct link between PINK1-mediated phosphorylation and p

146 These findings demonstrate a direct link between PKG signaling in distinct brain area

147 folate transport by mTOR signaling provide a direct link between placental function, gene methylation

148 The results demonstrate that there is a direct link between pneumococcal fermentative metabolism

149 g other characteristics, thus establishing a direct link between polar ejection forces and the direct

150 ediated permeability responses, indicating a direct link between PR and NR4A1.

151 egulation in T-cell progenitors and reveal a direct link between pre-TCR signaling and Notch1 express

152 neuronal calcium sensor-1 and speculate on a direct link between protein misfolding and calcium dysre

153 sed for structure determination, providing a direct link between protein structure, how a ligand bind

154 -mediated transcription, thus establishing a direct link between protein translation and HSF1 activit

155 r ambient and high CO2 conditions indicate a direct link between PS biosynthesis and ammonium assimil

156 However, no direct link between RABV and human disease has been defi

157 is in hotspot areas for radiation indicate a direct link between radiation and location of coronary s

158 Herein, we describe a direct link between rapid and short-lived poly(ADP-ribos

159 ven difficult to test this hypothesis, and a direct link between reactivity and electron donation has

160 e observations demonstrate an unexpected and direct link between recognition of CGIs by KDM2B and tar

161 I interferon (IFN-I) in lupus, suggesting a direct link between reduced CD11b activity and the chron

162 ene expression in tissues is suggestive of a direct link between repeated IgE-mediated activation of

163 egulated replication time and demonstrated a direct link between replication timing and gene expressi

164 Our work provides a direct link between RGM proteins and BMP signaling in vi

165 This route-switching provides a direct link between route selection and the folding and

166 These data provide a direct link between RSK2 and caspase-8 and identify a no

167 r tnfa in the mutant phenotype and suggest a direct link between SAH-induced methylation defects and

168 No evidence was found of a direct link between screening children and adolescents f

169 Our results reveal a direct link between selfhood and neural responses to hea

170 processing, in that they provide an unusual direct link between sensory (auditory/somatosensory) reg

171 These findings identify a direct link between sequence conservation and genomic fu

172 These findings emphasize a direct link between severity of acute injury and future

173 velopment and tumorigenesis, but until now a direct link between SF-1 and vascular remodeling has not

174 This finding demonstrates a direct link between single neurons and behavioral choice

175 Yet, a direct link between sleep restriction and alterations in

176 Pase activity of the motor, thus providing a direct link between structure and function.

177 gle-channel electrophysiology would enable a direct link between structure and function.

178 is that the central role of mTOR provides a direct link between T cell metabolism and function.

179 nce in situ hybridization (FISH), enabling a direct link between taxonomic identity and translational

180 a and PGC-1beta promoters, thereby forging a direct link between telomere and mitochondrial biology.

181 Here I reveal a direct link between temperature and ecologically relevan

182 ge, these findings show for the first time a direct link between TG2, NF-kappaB, and HIF-1alpha, demo

183 pecifically inhibited by IL-10, suggesting a direct link between the 5-lipoxygenase proinflammatory p

184 Our results demonstrate a direct link between the abrupt changes associated with v

185 Together, these data reveal a direct link between the abundance of Gag-specific expand

186 These results provide a direct link between the affinity of the TCR expressed by

187 These data reveal a direct link between the alpha4 integrin and actin polyme

188 rences between JAZ isoforms, and establish a direct link between the alternative splicing of JAZ pre-

189 wing and the Ne/ERN amplitude, questioning a direct link between the amplitude of this component and

190 bioactivity-guided fractionation revealed a direct link between the avoidance response of D. virgife

191 cteria in ferrous environments may provide a direct link between the biogeochemical cycles of nitroge

192 data provide in vitro evidence of a possible direct link between the CIA machinery and the mitoNEET c

193 Here, a direct link between the colloids concentration present i

194 This work reveals a direct link between the core reprogramming factors and m

195 These findings provide a direct link between the extracellular matrix-associated

196 containing RhoGEFs (RGS-RhoGEFs) represent a direct link between the G(12) class of heterotrimeric G

197 Our study provides a direct link between the growth factor signaling pathways

198 ToxT from binding to DNA in vitro provides a direct link between the host environment of V. cholerae

199 estoration of H3K4 methylation, suggesting a direct link between the IGF-1R signaling pathway and KDM

200 that context, GUCY2C signaling constitutes a direct link between the initiation of colorectal cancer

201 increasing experimental evidence suggests a direct link between the innate pentraxins and humoral Fc

202 measure silica particle spacings provides a direct link between the inter-particle spacing and the r

203 Desmin interacts with nebulin establishing a direct link between the intermediate filament network an

204 While this study provides a direct link between the kisspeptin pathway and metabolic

205 een criticized because they have not shown a direct link between the level of staffing and individual

206 Furthermore, these results provide a direct link between the lipid droplet and proteasomal pr

207 Studies of membrane proteins have revealed a direct link between the lipid environment and the struct

208 The direct link between the moving ribosome and RNAP provide

209 s a risk factor for thrombosis, although the direct link between the mutation and hemostatic disorder

210 pregulated upon injury, thus demonstrating a direct link between the neuroendocrine and cutaneous imm

211 Our findings support a direct link between the odds of depression and dietary G

212 Recent studies have shown that there is a direct link between the orientation of the nerve fibers

213 s provides evidence for theories proposing a direct link between the P300 component and the processin

214 Taken together, these observations provide a direct link between the periodic destruction of RAG-2 an

215 orrelates with trimer stability, providing a direct link between the presence of misfolded oligomers

216 A direct link between the primary cilia of mature dentate

217 Specifically, we forge a direct link between the PTEN-Akt-FOXO axis and the leuke

218 stic Cu64Zr36 metallic glass, we uncovered a direct link between the quasi-localized low-frequency vi

219 The results revealed a direct link between the thermal degradation of thiamine

220 Our results reveal a direct link between the transition to flowering and seco

221 Here, we demonstrate a direct link between the trial-to-trial variability of co

222 wever, the functional significance of such a direct link between the two types of developmental regul

223 dynamic acetylation is lost demonstrating a direct link between the two.

224 We now show a direct link between the XBP1 and NF-kappaB survival path

225 Metallothionein I as a direct link between therapeutic hematopoietic stem/proge

226 , and locomotor sensitization to cocaine, no direct link between these molecules has to date been exp

227 s and related metabolic diseases, although a direct link between these pathologies and HCCs has not b

228 ndothelium intermediate, providing the first direct link between these two precursor populations.

229 However, a direct link between TNR instability, the formation of no

230 This finding underscores the direct link between TRIM5 restriction and activation of

231 -type TTR but not L82A or L110A, providing a direct link between TTR-Abeta binding and TTR-mediated c

232 However, a direct link between tumour hypoxia and tolerance through

233 Our study reveals a surprising direct link between two major cellular transcriptional n

234 suppression of Wnt signalling and provides a direct link between two major dorsoventral morphogenetic

235 The hypothesis provides a direct link between V1 neural responses to a visual loca

236 des precise measurements of adaptation and a direct link between visual percepts and neural responses

237 f an organism's life history, and there is a direct link between visual pigment phenotypes and opsin

238 nt accessory olfactory bulb mitral cells-the direct link between vomeronasal sensory input and limbic

239 lication of our system, we used it to reveal direct links between antimalarial drugs and their native

240 However, direct links between climate and violence are unlikely b

241 To identify direct links between cytokinins and nodule organogenesis

242 unction and disease mechanisms and providing direct links between dysregulated metabolism and cancer.

243 We concluded that the direct links between fundamental drivers and growth rate

244 The multi-omics data are integrated through direct links between genes and proteins and further conn

245 As a result we are able to establish direct links between individual-level and population-lev

246 However, there are no direct links between LA and CeM.

247 d with reaction time facilitation, providing direct links between neural and performance metrics of m

248 enetically guided anatomical mapping provide direct links between neuron identity, peripheral anatomy

249 On all surfaces, populations exhibited direct links between surface residence time, rate of dif

250 owever, despite the convergence of evidence, direct links between the genetic and proteomic findings

251 The identification of direct links between the levels would facilitate use of

252 These transcriptional programs thus provide direct links between the mechanisms controlling the lami

253 n of gene expression and provide evidence of direct links between the two.

254 A more direct link can be shown with methods that manipulate os

255 symbioses(3,4), but there has yet to be any direct link demonstrated between iridescence and photosy

256 portantly, this study provides evidence of a direct link for crosstalk between T cells and epithelial

257 Direct links for each gene to UCSC eukaryotic and microb

258 ish biomass production provides an unusually direct link from biodiversity to critical ecosystem serv

259 In summary, we have described a direct link from CFTR to Ezrin to PI3K/AKT signaling tha

260 SC to this medial frontal area, suggesting a direct link from dorsal hippocampal networks involved in

261 by modulating dopamine signaling, although a direct link has never been demonstrated.

262 al instability of mitotic chromosomes, but a direct link has never been established.

263 However, a direct link has not been established between dopamine re

264 However, its direct link in vivo and the underlying mechanisms that c

265 atistical fidelity of the imperfect model, a direct link is developed between the predictive fidelity

266 To date, however, there has been no direct link made between noise exposure, cochlear neurop

267 However, no direct link of an interplay between the two phases has b

268 The only known direct link of p38 to translation machinery is the MAPK

269 Our results provide a direct link of the involvement of TaGT43-4, TaGT47-13, a

270 network, thus being unique in establishing a direct link of upstream effectors to a key neural crest

271 t least 1 order of magnitude, allowing for a direct linking of quantitative fluorescence analysis to

272 A direct-link PK/PD model predicting the time course of S6

273 This allowed development of a direct-link PK/PD model that predicted PBMC S6K1 inhibit

274 sized that impaired CN regulation provides a direct link to abnormal signaling of neuronal calcium ch

275 eletal muscle physiology, and they provide a direct link to androgen signaling.

276 y protein cortactin, potentially providing a direct link to Arp2/3-based actin dynamics during EGFR d

277 and suspensor but does not support a strong direct link to auxin response.

278 With a direct link to cancer, aging, and heritable diseases as

279 ply that automethylation of CARM1 provides a direct link to couple transcription and pre-mRNA splicin

280 d at a continental scale while maintaining a direct link to ecologically relevant, climate-related st

281 associated with sleep problems, evidenced no direct link to functional disability.

282 strongly supported by behavioral evidence, a direct link to neural oscillations and oscillatory entra

283 hese nutrient mobilization mechanisms have a direct link to seagrass-derived radial O2 loss and secre

284 ristic of a range of pyroxenes, confirming a direct link to the basaltic howardite-eucrite-diogenite

285 omic region and do not necessarily provide a direct link to the biological mechanisms underlying thei

286 Mediator-dependent manner, thus providing a direct link to the general transcription machinery.

287 pecific biochemical activity for Shq1p and a direct link to the H/ACA snoRNP.

288 demonstrate phosphoregulation of Mga and its direct link to virulence in M59 GAS strains.

289 hose products are involved in adhesion, with direct links to B-T cell interactions.

290 LDs' spatial-temporal dynamics, which showed direct links to cellular lipid metabolisms and can separ

291 al processes and stress responses, providing direct links to clock-controlled pathways and suggesting

292 emism, membership in a terrorist faction, or direct links to leadership.

293 acid converts the exocyclic double bonds to direct links to the ortho-positions of both adjacent mes

294 NA genes in genomic context are provided via direct links to the UCSC genome browsers.

295 Thus, a direct link was found between CP110 and CDK2 inhibitor a

296 A direct link was made to at least one form of cicatricial

297 The voice is the most direct link we have to others' minds, allowing us to com

298 ution of the retrieved DNA adducts hint at a direct link with an increase in NOCs and LPOs upon red (

299 e, Ca(2+) signals preceding egress and their direct link with motility, an essential virulence trait.

300 t risk factor for global disease burden, but direct links with cardiovascular disease mortality are l