ライフサイエンスコーパス: direct repeat

1 r genome is 46,214 bp with a 237 bp terminal direct repeat.

2 the 10 loci contained exact integers of the direct repeat.

3 vealed a tandem PhoP dimer that bound to the direct repeat.

4 occurred at position 6488 generating a 3 bp direct repeat.

5 egion flanked at each terminus by a sizeable direct repeat.

6 two GATA-binding motifs and three octameric direct repeats.

7 typically consist of a tandem arrangement of direct repeats.

8 instability of DNA segments flanked by short direct repeats.

9 mino-acid (aa) direct repeats, and two 88-aa direct repeats.

10 scription by binding in tandem to target DNA direct repeats.

11 displays a 4977-bp deletion flanked by short direct repeats.

12 containing small palindromes embedded within direct repeats.

13 ying genes of unknown function surrounded by direct repeats.

14 and most of these elements are organized as direct repeats.

15 p single deletion in mtDNA, without flanking direct repeats.

16 degree of specificity is associated with the direct repeats.

17 t to a series of non-homologous short (6 bp) direct repeats.

18 flanked on either side by 3.73-kb identical direct repeats.

19 ent of a PolII complex, is also unstable for direct repeats.

20 te is located) adjacent to a series of short direct repeats.

21 from cut sites within, or adjacent to, short direct repeats.

22 e half sites that constitute the overlapping direct repeat 1 (DR1) and direct repeat 2 (DR2) motifs a

23 templates for these template switches, with direct repeat 1 (DR1) and DR2 for primer translocation a

24 cleavage generates the plus-strand primer at direct repeat 1 (DR1).

25 binding to the PPAR response element, called direct repeat 1 (DR1).

26 end of the minus-strand DNA overlapping the direct repeat 1 in avihepadnaviruses.

27 tes proopiomelanocortin through binding of a direct repeat 1 response element in the promoter, and th

28 y shift assay shows that TR4 can bind to the direct repeat 1 sequence element (AGGTTAAAGGTCT, nucleot

29 initiate plus-strand DNA synthesis from the direct repeat 2 (DR2) located near the opposite end of t

30 te the overlapping direct repeat 1 (DR1) and direct repeat 2 (DR2) motifs and two forkhead factor bin

31 omni immunoglobulin-binding protein A (IbpA) direct repeat 2 Fic domain (DR2/Fic) for natural host ta

32 sequence (174,601 bp) flanked by a terminal direct repeat (2,910 bp).

33 vated the human ABCA1 promoter, via the same direct repeat 4 (DR4) promoter element as LXR/RXR.

34 ated by a 4-nucleotide spacer similar to the direct repeat 4 element and is designated as a putative

35 receptor/retinoid X receptor (LXR/RXR) on a direct repeat 4 element in the CETP promoter.

36 ponse GADD45beta gene by binding to a distal direct repeat 4 site of the GADD45beta promoter.

37 X receptor (RXR) or CAR-RXR heterodimers to direct repeat-4 type nuclear receptor-binding sites foun

38 e mature dorsal spinal cord, expression of a direct repeat 5 RA response element (DR5-RARE) transgene

39 site (TSS) identified 3 conserved hexameric direct repeat-5 elements, RARE1, -2 and -3, and a half s

40 w that the transposon is flanked by an 18-bp direct repeat, a copy of which is also present at the ta

41 efore these deletions, were flanked by short direct repeats, a unique signature of intrachromosomal i

42 These sequences are arranged as direct repeats, an arrangement that can be recognized by

43 xclusively A+T-containing segment, five 9-bp direct repeats, an inverted repeat, and a sigma(A)-depen

44 we created plasmid x chromosome, chromosomal direct repeat and allelic recombination substrates in wh

45 n (UTR) upstream of synA was found to have a direct repeat and an inverted repeat that overlapped thr

46 in intergenic regions and RNAs from the long direct repeat and hok/sok elements.

47 NA packaging (pac) site containing two 21-bp direct repeats and a major terminase cleavage site in th

48 While direct repeats and imperfectly homologous sequences appe

49 mes is due primarily to the transposition of direct repeats and insertion sequence (IS) elements.

50 ICE6013 is flanked by 3-bp direct repeats and is demarcated by 8-bp imperfect inver

51 4-bp region containing the deletion had four direct repeats and one inverted repeat.

52 surrounding the deletion contained two 4-bp direct repeats and that a hairpin structure could be for

53 motifs, inverted repeats, mirror repeats and direct repeats and their associated subsets of cruciform

54 d repeats, inverted repeats, mirror repeats, direct repeats and their corresponding subsets: crucifor

55 Perfect direct repeats and, in particular, the prominent 13 bp r

56 Comparative analysis suggests that a short direct repeat, and a secondary structure including the t

57 R) as scored using a reporter that harbors a direct repeat, and are prone to gross chromosomal rearra

58 ovar Typhimurium strain LT2 was analyzed for direct repeats, and 54 sequences containing variable-num

59 es at a tRNA-methionine locus, is flanked by direct repeats, and encodes a P4-like integrase.

60 spontaneous point mutation, deletion between direct repeats, and intergenomic recombination.

61 ng elements are flanked by either 8- or 9-bp direct repeats, and they differ significantly in size co

62 and cleavage site, three 46-amino-acid (aa) direct repeats, and two 88-aa direct repeats.

63 imilarity); (ii) a central domain containing direct repeats; and (iii) a C-terminal domain that is si

64 erminal inverted repeats, usually flanked by direct repeats; and compared IS-interrupted sequences wi

65 ides an explanation of why both inverted and direct repeats are maintained and how they contribute to

66 Segments flanked by short direct repeats are relatively common in different region

67 s accommodate simultaneous binding of Int to direct-repeat arm sites and indirect-repeat core sites a

68 by recombinational events between nontandem direct repeats as short as 8 bases, and (iii) substituti

69 The presence of A-tails and flanking direct repeats associated with these sequences supported

70 etion inactivated lpr0035, removed the 49-bp direct repeat at the 5' junction of pLP45, and locked pL

71 us type 1 (HSV-1) a sequence is present as a direct repeat at the two termini of the 152-kilobase vir

72 re maintained in all isolates, the number of direct repeats at a locus was polymorphic.

73 The deletions had no or small direct repeats at the breakpoint region.

74 correspondence to the position of two 13-bp direct repeats beginning at nucleotides 8470 and 13 447.

75 ectly bound a region of DNA containing three direct repeats between Pmra and the mraZ gene.

76 ions, each comprised of a novel set of three direct-repeat binding sites spaced 21 bp apart on center

77 A consensus sequence for the two direct repeats bound by HrpY is proposed.

78 deleted, binding was still specific for the direct repeat but was much weaker and appeared to requir

79 eak was made between two copies of a 1290-bp direct repeat by mobilizing a P transposon.

80 with cell source) GC-rich copies of a 102-bp direct repeat (called IR 4) flanked by small unique sequ

81 We show here that transgenes with intrinsic direct repeats can also induce PTGS at a very high frequ

82 HR between linked, direct repeats can occur by gene conversion without an a

83 A single direct-repeat cassette of the element (2x CLE) enhances

84 pes can amplify by unequal exchanges between direct repeats (CD), and both are rare in unselected cul

85 ses its own CRISPR array with short and long direct repeats, cleaves target RNA, and exhibits collate

86 ions, we regularly detected the formation of direct repeats close to the break sites, independent of

87 lA box is 17 nucleotides long and contains a direct repeat comprised of two hexamers separated by 5 n

88 t tcpA, two toxbox elements are present in a direct repeat configuration and both are required for ac

89 ntly, when the RFB is positioned between the direct repeat, conservative gene conversion events predo

90 the nanomolar range, and binds to these two direct repeats cooperatively.

91 strated that COUP-TFII binds to an imperfect direct repeat COUP-TFII recognition sequence (termed her

92 ne conversion and increased both spontaneous direct repeat deletion and spontaneous allelic conversio

93 in vivo trans-complementation assay in which direct repeat deletion through template switching recons

94 o test the recombination-related property of direct repeat deletion, were encapsidated in virions eng

95 ined by using a previously described in vivo direct-repeat deletion assay.

96 cant association of the endpoints with short direct repeats, despite the fact that several such repea

97 repeats, as well as the short host sequence direct repeats diagnostic of insertion.

98 A mutation in the downstream direct repeat DNA sequence allowed high mobility complex

99 Finally, we show that a direct repeat DNA sequence within the hrtAB promoter is

100 s target genes containing two hexanucleotide direct repeat DNA-response elements separated by one bas

101 ange the affinity of AraC for binding to two direct-repeat DNA half-sites.

102 An evolutionarily conserved direct repeat (DR) element, a canonical binding site for

103 s based on target sequences (spacers) in the direct repeat (DR) region (14).

104 CARs are inactive on classical CAR-inducible direct repeat (DR)-4 elements, yet efficiently transacti

105 GTTCA-like direct repeat with a 4 bp spacer [direct repeat (DR)-4)].

106 We report here the generation of a Direct Repeat (DR)-GFP reporter-based mouse model to stu

107 evious report has identified a non-consensus direct repeat (DR-1) element in the RXRgamma2 gene promo

108 ear orphan receptors EAR2 and EAR3 through a direct-repeat (DR) motif.

109 five Rep monomers bind five tetranucleotide direct repeats; each repeat is recognized by two Rep mon

110 definitive, a protein complex that binds to direct repeat elements in the embryonic and fetal beta-t

111 4) were previously shown to bind in vitro to direct repeat elements in the mouse and human embryonic

112 of 220- to 390-nucleotide degenerate tandem direct repeats encoding putative DNA binding proteins.

113 r receptors comprise the DNA-binding core of direct repeat erythroid definitive, a protein complex th

114 ene repressor activity, which we named DRED (direct repeat erythroid-definitive).

115 ng consistency of raw and final data and for directing repeat experiments.

116 Additionally, direct repeats flank two-thirds of the reported mitochon

117 eparated by a coupling sequence derived from direct repeats flanking chromosomal copies of ICEF as a

118 f the element, that corresponded to the 3-bp direct repeats flanking the chromosomal forms.

119 s reports, several of these Ds elements lack direct repeats flanking the deletion junctions and fille

120 -related integration and excision genes, and direct repeats flanking the island, suggest it moves as

121 f conserved sequences, which contained short direct repeats, flanking a variable region.

122 SP-responsive genes were not preceded by the direct repeats found in S. pneumoniae.

123 rm reveals the loss of three of 10 imperfect direct repeats from the central region of the lumenal do

124 The fluorescent yellow direct-repeat (FYDR) mice described here carry two diffe

125 ct or by monomeric DNAs containing a pair of direct repeat GAA.TTC sequences.

126 aliana, was previously shown to contain four direct repeats (Gap boxes, located between -237 and -181

127 by slipped mispairing between 2 copies of a direct repeat (GCGAGCACGAC) separated by 4 bp.

128 ssion of ATPase(-) Rad54 reduced spontaneous direct repeat gene conversion and increased both spontan

129 dent single-strand annealing at the flanking direct repeats, generating a deletion.

130 ing HeLa cell lines harbouring an integrated direct repeat green fluorescent protein reporter for DSB

131 at ComE protects sequences inclusive of both direct repeats, has an equilibrium dissociation constant

132 DNA damage and on both interchromosomal and direct repeat heteroallelic recombination.

133 e, consisting of two motifs of two imperfect direct repeat hexamers spaced by four nucleotides and a

134 nting analysis that includes three imperfect direct repeat hexamers that are needed for full occupanc

135 nting analysis that includes three imperfect direct repeat hexamers.

136 (ssDNA) via a few bases (<5 nt) or extensive direct repeat homologies (>20 nt).

137 es gene expression via binding to the AGGTCA direct repeat hormone response element.

138 Alternatively, direct repeat HR can occur by gene conversion with a cro

139 NA-PKcs on DSB-induced HR, we integrated neo direct repeat HR substrates carrying the I-SceI recognit

140 The element is bordered by two 17-bp direct repeats identical to those found flanking staphyl

141 res the presence of a LytTR family consensus direct repeat in order to stably bind DNA.

142 sequences to stimulate deletion of flanking direct repeats in Escherichia coli.

143 That H. pylori possesses direct repeats in regions where potential gene rearrange

144 gested that purified ComE binds to two 11-bp direct repeats in the nlmC-comC promoter region, where C

145 ed by DNase I protection assays to a pair of direct repeats in the P2 and P3 promoter regions of the

146 ntly as a monomer to each toxbox in the tcpA direct repeat, in accordance with what we observed previ

147 ISs and their sequence elements-inverted and direct repeats-in raw read data or contigs using flexibl

148 The deleted region, which is flanked by two direct repeats, includes three exons of STX16, the gene

149 ound in the database were flanked by 9-14 bp direct repeats, indicating that their transposition was

150 a primary determinant of PTGS referred to as direct repeat-induced PTGS (driPTGS).

151 increase in genome instability, detected as direct-repeat instability.

152 oreover, we determined that a minimum of two direct repeats is required to form a stable complex and

153 al sequence composed of four 12-bp imperfect direct repeats (iterons) in the pBtoxis minireplicon was

154 Two 6 bp direct repeats located at the ends of this region appear

155 A spacers interspersed direct repeat locus containing 32 nearly perfect 29-bp r

156 due to asymmetric insertion of IS6110 in the direct repeat locus.

157 nclude the dnaA-dnaN and NTF regions and the direct repeat locus.

158 yping based on the polymorphism in the 36-bp direct-repeat locus was also performed.

159 of toxboxes organized as either inverted or direct repeats may be required for full activation.

160 s in increased mitochondrial frameshifts and direct-repeat mediated deletions but has no effect on th

161 r the first time in mammalian cells, a short direct repeat-mediated noncanonical splicing event induc

162 system to simultaneously monitor spontaneous direct-repeat-mediated deletions (DRMDs) in the nuclear

163 enetic reporter to measure the rate at which direct-repeat-mediated deletions arise in the mitochondr

164 which these deletions arise is unknown, but direct-repeat-mediated deletions involving polymerase sl

165 ast that have an impact on the generation of direct-repeat-mediated deletions.

166 recombination (HR; using fluorescent yellow direct repeat mice), and transcript levels for several r

167 HR in vivo, we have used fluorescent yellow direct repeat mice, in which an HR event at a transgene

168 Meanwhile, two copies of a 146-bp direct repeat motif flanking the deleted region were fou

169 Within the enhancer is a TGACCT direct-repeat motif, required for enhancer activity, tha

170 combinant Ear2 specifically binds the TGACCT direct-repeat motif.

171 es, Xenopus treacle has 11 highly homologous direct repeats near the center of the protein molecule s

172 ected region of 26 to 28 bp encompassing two direct repeats, NTTAAG-n5-WTTAAG, 10 bp upstream of the

173 A direct repeat of 17-24 bases was found on the ends of al

174 he ATPA regulatory element 1 is an imperfect direct repeat of a nuclear receptor response element (A/

175 A direct repeat of an 8-base AU sequence within the 3'-non

176 Hap1 is unusual in binding a direct repeat of CGG triplets, in contacting a TA in the

177 9 proviruses analyzed were flanked by a 6-bp direct repeat of host sequences, as is characteristic fo

178 R64 and R100, which are joined at a 1,953-bp direct repeat of IS100.

179 A perfect direct repeat of the delivered DNA, and inverted and imp

180 odimer, BR-Base-a1-Acid-a1-BR, can bind to a direct repeat of the GCN4 half-site in vivo, leading to

181 A direct repeat of the pentamer GGGGC is present adjacent

182 proximal portion of the enhancer contains a direct repeat of two E-Box motifs, which contributes mos

183 A functional retinoic acid response element direct repeat of two novel motifs separated by a 5-bp sp

184 he enhancer (URE) consisting of three tandem direct repeats of 47 bp.

185 This upstream region contained five direct repeats of 59 base pairs (bp) that increased thym

186 as a highly cooperative dimer by recognizing direct repeats of 7-bp motifs with a 4-bp spacer.

187 spot' of recombination composed of multiple direct repeats of a 5 bp sequence motif, which recombine

188 At least two direct repeats of AGGTCA-like sequences with 4-base spac

189 C. trachomatis Tarp possesses up to six direct repeats of approximately 50 amino acids each.

190 Direct repeats of Arabidopsis telomeric sequence were co

191 ons are situated within tandem or non-tandem direct repeats of at least 5-bp and may be explained by

192 g analysis revealed that MtrA recognizes two direct repeats of GTCACAgcg-like sequences and that MtrA

193 We found that p53REs are not only direct repeats of half-sites; rather, two p53 half-sites

194 show acts with high efficiency via terminal direct repeats of only 28 bp and with reduced but measur

195 containing the inverted repeat of pAM373 and direct repeats of pAD1 was mobilized efficiently by pAD1

196 silencing induced by a transgene with three direct repeats of the beta-glucuronidase (GUS) open read

197 Synthetic DNA cassettes harboring direct repeats of the CLE motif were placed upstream fro

198 strong TRE consisting of two nearly perfect direct repeats of the consensus nuclear hormone receptor

199 ulated genes have defined canonical RAREs as direct repeats of the consensus RGKTCA separated by 1, 2

200 have recently been identified that resemble direct repeats of the hexameric half-site (ADR3).

201 rom a 2-bp difference between the downstream direct repeats of the P2 and P3 sites.

202 Direct repeats of the sequence TGT-N(11)-ACA and a stati

203 We found that a minimum of three direct repeats of the sequence TTTTGAT is required for T

204 splicing factor composed almost entirely of direct repeats of the tetratricopeptide repeat (TPR) pro

205 opy F'(128) plasmid, where lac is flanked by direct repeats of the transposable element IS3 (1258 bp)

206 bers of nucleotides between distantly spaced direct repeats of three or more base pairs.

207 ty in either assay, either by removal of the direct repeat or by mutation of RAD52, increased the rel

208 pair of repeat tracts where n> or =60 in the direct repeat orientation in vitro.

209 s a pair of ToxT binding sites arranged in a direct repeat orientation upstream of the core promoter

210 a pair of long GAA.TTC repeat tracts in the direct repeat orientation.

211 esent in a single plasmid DNA and are in the direct repeat orientation.

212 usly, one MDS and its outgoing (3') pointer (direct repeat) overlap intron splice sites, indicating t

213 Inverse repeat p53REs favor the H14 mode and direct repeat p53REs may have high possibilities of othe

214 c switch, including PhoP with its associated directed repeat PHO box, candidate motifs for two SARPs,

215 ansversions affecting nucleotides within two direct repeats present in the TcpP-binding region (TGTAA

216 ic homologous recombination between flanking direct repeats, primarily Ty1 elements.

217 o1 promotes replication fork barrier-induced direct repeat recombination but intriguingly limits reco

218 mologue Rqh1 for DNA repair and promotion of direct repeat recombination in the fission yeast Schizos

219 lays a major role in limiting Exo1-dependent direct repeat recombination induced by replication fork

220 Direct repeat recombination induced by ultraviolet light

221 ly unstable and is lost at high frequency by direct repeat recombination involving the loop sequence.

222 We show here for the first time that direct repeat recombination, dependent on Rad22 and Rhp5

223 Rates of mutations, direct repeat recombination, or retrotransposition were

224 fect unequal sister-chromatid recombination, direct-repeat recombination, or mutation.

225 ral genome with a single fully reconstituted direct repeat region (DR) with both terminal cleavage an

226 pacers" separating insertion elements in the direct repeat region of the M. tuberculosis genome.

227 tion may be possible through the inverted or direct repeat regions, while horizontal gene transfer se

228 One mutation defined a cis-acting adjacent direct repeat required for optimal spxB transcription.

229 PAT and kangaroo both contain split direct repeat (SDR) termini, and here we show that DIRS-

230 lindrome separated by 17 bases) and DR-11 (a direct repeat separated by 11 bases) in the 5'-flanking

231 hormone receptor-binding hexad arranged as a direct repeat separated by one nucleotide (DR-1) in the

232 trated that FsrA also binds to two imperfect direct repeats separated by 13 bp, based on the consensu

233 r, conversion frequencies were identical for direct repeats separated by 3800 bp of transcriptionally

234 se proteins generally binds to two imperfect direct repeats separated by a number of bases that place

235 tection region in the P1 promoter contains a direct repeat sequence (GTTAAN(6)GTTAA [where N is any n

236 btr is relieved and Btr binds to a conserved direct repeat sequence adjacent to feuA to activate tran

237 sults, we concluded that SaeR recognizes the direct repeat sequence as a binding site and that bindin

238 DMD methylation is in turn controlled by a direct repeat sequence immediately downstream of the DMD

239 The data also demonstrate that deletion of a direct-repeat sequence restricts the mobility of pLP45 a

240 promoter region containing a 37-bp imperfect direct-repeat sequence.

241 Btr binds to two direct repeat sequences adjacent to the -35 region; reco

242 interaction of TcpP with nucleotides of the direct repeat sequences appears to be a prerequisite for

243 lves an initial pairing of the complementary direct repeat sequences followed by complete hybridizati

244 in a manner dependent on the availability of direct repeat sequences in the transgene.

245 on of a double-strand break (DSB) flanked by direct repeat sequences is mediated by single-strand ann

246 s specifically to dsDNA containing the oriT2 direct repeat sequences, confirming their role in transf

247 criptional terminator stem-loop and a set of direct repeat sequences, DRa and DRb, located at the 5'

248 a short stretches [5-20 nucleotides (nt)] of direct repeat sequences, yielding deletions of interveni

249 episomal and chromosomal targets containing direct repeat sequences.

250 rization thus drive Hap1 selectivity for CGG direct repeat sites that contain an asymmetrically posit

251 n many aspects, e.g., having TIR signals and direct repeats, small in size, noncoding, able to fold i

252 D surface is operative for dimerization with direct repeats spaced by 4 base pairs (DR-4) and with th

253 ity factor binds in vitro to three imperfect direct repeats, spaced 10 base pairs apart, in a sequent

254 tescibacteria LexA-binding motif has unusual direct-repeat structure, and comparative analyses reveal

255 the saddle-shaped TBP molecule, with its two direct-repeat subdomains and pseudo-two-fold symmetry.

256 quence comprising two loosely conserved 8-bp direct repeat subunits separated by 3 nucleotides.

257 entical inverted repeats and enclosed within direct repeats, suggesting that these genetic regions mi

258 ases) genomes, that have similarly extensive direct repeats, suggests that recombination between such

259 hanisms by which TERT domains and RNA motifs direct repeat synthesis.

260 wo GATA motifs in palindromic (Pal-GATA) and direct-repeat (Tandem-GATA) arrangements, respectively,

261 inding of OmpR family response regulators to direct-repeat targets.

262 of these regions revealed two sets of a TCT direct repeat [TCT-N8-TCT] present at positions (-107 to

263 composed of multiple copies of 23-amino-acid direct repeats, termed DR2 and DR1.

264 Trans-splicing of eri-6/7 is mediated by a direct repeat that flanks the eri-6 gene.

265 mutations are associated with palindromic or direct repeats that are either perfect or imperfect.

266 The latter was flanked by inverted/direct repeats that are substrates of SB.

267 It carries 3 tandem direct repeats that comprise 58% of the protein.

268 eous deletion mutations often occur at short direct repeats that flank inverted repeat sequences.

269 ers P(RE), P(I), and P(AQ) by binding to two direct repeats that flank the promoter -35 element.

270 donor DNA, deletions of up to 5 kb involving direct repeats that flank the psbA gene were obtained.

271 Recombination between direct repeats that flank the R-M cassette allows for it

272 results in instability of sequences between direct repeats that is dependent on transcription of the

273 by site-specific recombination within 60 bp direct repeats that mark the junctions between ICEBs1 an

274 n size from 81 to 107 bp, and are flanked by direct repeats that vary in length from 6 to 8 bp.

275 rains lacked the missing DNA between the two direct repeats that was found in all large ascospore-der

276 Our results show that MelR binds as a direct repeat to site 2 and site 2' with the C-terminal

277 We showed that MelR binds as a direct repeat to these sites, and we proposed a model to

278 ases has no effect on strand misalignment at direct repeats to produce deletion.

279 oters contain a common regulatory element, a direct repeat typical of OmpR-class transcription factor

280 The aims of this study were to apply direct repeat unit (dru) typing in a large collection of

281 DNA sequence analysis of the direct repeat units within the mec determinant of 30 USA

282 r and that phosphorylated HssR binds to this direct repeat upon exposure of S. aureus to high concent

283 Mutation of this 70-bp UTR and of the direct repeat upregulated both syn and ctr transcription

284 tinylated oligoribonucleotide containing the direct repeat was used as an affinity ligand to purify t

285 recent study, the abundant presence of short direct repeats was documented by comparative bioinformat

286 tion between long CTG.CAG tracts oriented as direct repeats was extraordinarily high; recombinants we

287 d by bacteriophage P1 loxP sites oriented as direct repeats was inserted within a selected gene.

288 The two direct repeats were believed to be responsible for the d

289 he delivered DNA, and inverted and imperfect direct repeats were detected in the same transgene locus

290 uences and status of the 11 bp TIRs and 8-bp direct repeats were determined.

291 Two conserved 7-bp direct repeats were found immediately upstream of the fs

292 Furthermore, similar direct repeats were found upstream of cslAB, comED, comX

293 The P1 phage loxP sites are identical 34-bp direct repeats, whereas the phiC31 phage attB/attP sites

294 of (i) a variable region containing multiple direct repeats which differ in number and sequence from

295 ent PXR DNA-binding motif is the AGTTCA-like direct repeat with a 4 bp spacer [direct repeat (DR)-4)]

296 bsite appears to be oriented as an imperfect direct repeat with its adjacent subsite, although base s

297 heritability, we propose that the intrinsic direct repeat within a transgene may act as a primary de

298 iations resulting from loss or gain of long, direct repeats within the protein coding sequences.

299 in an 11.3-kb segment of DNA flanked by 7-bp direct repeats within the serotype 4 strain which is not

300 iously showed that CpG-rich imperfect tandem direct repeats within three different mouse DMDs (Snurf/