ライフサイエンスコーパス: directional selection

1 lar to those expected under models of recent directional selection.

2 ear several hallmarks of the effects of past directional selection.

3 e frequency spectra do not support models of directional selection.

4 We were unable to detect either balancing or directional selection.

5 e protein sequence has changed rapidly under directional selection.

6 tion-dependent traits, even under consistent directional selection.

7 inversion breakpoints or are near targets of directional selection.

8 hat some of the loci have experienced recent directional selection.

9 out the costs usually associated with strong directional selection.

10 suggests the possibility of species-specific directional selection.

11 were unavailable in populations subjected to directional selection.

12 equences of modular patterns being molded by directional selection.

13 ates evolution by increasing the strength of directional selection.

14 from 2008 to prospect for loci under recent directional selection.

15 between Oryza species were partly driven by directional selection.

16 vidence consistent with the action of linear/directional selection.

17 features characterising spatial variation in directional selection.

18 tion; and detect recent balancing as well as directional selection.

19 ersity can both be shaped by stabilizing and directional selection.

20 causative mutations as a response to strong directional selection.

21 extended haplotype, consistent with positive directional selection.

22 infer the mutation rate and the strength of directional selection.

23 hism similar to that observed under positive directional selection.

24 ws genealogy and extended LD consistent with directional selection.

25 rapid increases in frequency expected under directional selection.

26 ineage, features that point to the action of directional selection.

27 Estimates of the magnitude of directional selection (absolute value of beta) were expo

28 of the cardini group) provides evidence for directional selection across species.

29 These results are best explained by positive directional selection acting at or near intron 7 and dem

30 pulation differentiation are consistent with directional selection acting on the class IIalpha-linked

31 y scenarios and suggests a history of strong directional selection acting on the posterior lobe.

32 in both African and non-African samples; and directional selection, acting during the geographic expa

33 In contrast, directional selection acts to alter the developmental pr

34 In the presence of such strong directional selection, alleles enhancing a particular tr

35 ivity will evolve under conditions of strong directional selection, an observation that helps interpr

36 We analyze this interaction of directional selection and background selection and study

37 tive genetic variance of traits under strong directional selection and fixation of genes conferring t

38 y weak relative to classical models, such as directional selection and overdominance.

39 compared to orthologs, suggesting increased directional selection and/or relaxed selection on both g

40 he average recognition ability (a measure of directional selection) and the standard deviation of rec

41 dN/dS) are a clear indicator of positive, or directional, selection, and several recently developed m

42 om D. simulans suggests that many targets of directional selection are shared between these species.

43 re (1984-1997) that reported the strength of directional selection as indexed by standardized linear

44 these two proteins are evolving under strong directional selection, as has been reported for the alph

45 Most models of positive directional selection assume codominance of the benefici

46 g-term effects of genetic interactions under directional selection assuming no mutation or dominance,

47 ts, we found high incidence of signatures of directional selection at 19 loci.

48 on random field population genetics model of directional selection at DNA sites.

49 at there has been historical but not current directional selection at fimA between E. coli and Salmon

50 ed that thermogenic capacity is under strong directional selection at high altitude.

51 from all 6 populations identified signals of directional selection at known drug-resistance loci, inc

52 ngly suggest this reduction is due to recent directional selection at or near per within D. p. bogota

53 To characterize the signature of directional selection at this locus, we surveyed DNA seq

54 for all traits apart from horn growth, with directional selection being stronger under more adverse

55 vel, we find gene expression differences and directional selection between humans and chimpanzees mor

56 evidence for an unusual mix of balancing and directional selection but no evidence of stable geograph

57 Several other QTL experienced strong directional selection, but only in one site and seasonal

58 This is possibly influenced by directional selection, but the slightly higher variance

59 None of the mutations were suggestive of directional selection by ARTs.

60 We also demonstrate that directional selection can have marked effects on the mod

61 We show that directional selection, compared to stabilizing selection

62 ization) or greatest for traits under strong directional selection (condition dependence), but few st

63 heses, the femur was subject to little or no directional selection despite having shorter values by l

64 ion mean be close enough to the optimum that directional selection does not overwhelm balancing selec

65 sure or temporal variation in the targets of directional selection during breeding probably associate

66 and that inherited polymorphisms may undergo directional selection during clonal expansion of tumors.

67 volution is free to proceed at high rates of directional selection during the organization of a new s

68 Hv, we can quantitatively estimate that the directional selection exerted by Hv males on Hs females

69 simple mathematical model, we show that weak directional selection for a large neonate, a narrow pelv

70 ion subjected to 10 recurrent generations of directional selection for early flowering in a single te

71 two environments were considered separately, directional selection for height was detected under low

72 utionary partners that can alternate between directional selection for high fertilization ability and

73 e basis of the directionality of QTL, strong directional selection for increased achene size appears

74 static genetic variance and evidence of past directional selection for increased body size.

75 There is no indication of directional selection for increased human microsatellite

76 hes zero, providing the potential for strong directional selection for increasing predator speed at h

77 election on reproductive lifespan as well as directional selection for longer reproductive lifespan.

78 geographic hypotheses, the humerus was under directional selection for longer values by latitude.

79 ure of genetically based niche variation and directional selection for niche evolution in the experim

80 etic variation in the microhabitat niche and directional selection for niche evolution were not detec

81 genetic drift, even in the face of constant directional selection for one particular protein archite

82 ral accession, indicating past occurrence of directional selection for seed size.

83 ted a depressed He, consistent with positive directional selection for sulfa resistance mutations.

84 ryza sativa-infecting isolates showed higher directional selection from host and subsequently tends t

85 s coevolution processes is greatly driven by directional selection from host plants.

86 have found robust statistical evidence that directional selection has acted on male traits, by confi

87 Positive directional selection has driven the evolutionary fixati

88 ggesting that at least one episode of strong directional selection has occurred in the region.

89 stigation of nucleotide diversity supports a directional selection hypothesis.

90 o do so, we considered a coalescent model of directional selection in a sensible demographic setting,

91 ic hitchhiking, we analyze a simple model of directional selection in a subdivided population.

92 Evidence suggests that directional selection in allopolyploids rarely acted on

93 phic bottlenecks and detecting signatures of directional selection in bottlenecked populations, despi

94 Strong directional selection in concert with genetic hitchhikin

95 Colony size was under both stabilizing and directional selection in different years, and reversals

96 nd indicate that the putative involvement of directional selection in host-parasite coevolution and g

97 nity genes, suggesting an important role for directional selection in immune system protein evolution

98 e presence of glyphosate and strong negative directional selection in its absence may indicate that t

99 QTL) sign test to evaluate the importance of directional selection in phenotypic divergence.

100 an be mapped by looking for the signature of directional selection in polymorphism data.

101 However, the overall importance of directional selection in shaping the W chromosome is unk

102 genes whose regulation likely evolved under directional selection in the ancestral primate lineage.

103 stence and appears to have been under strong directional selection in the last 5,000 years, evidenced

104 aration of a founding population followed by directional selection in the new environment.

105 The combination of strong positive directional selection in the presence of glyphosate and

106 Responses to directional selection in the tibia and radius induced a

107 Long-term, single-trait, bi-directional selection in the Virginia chicken lines has

108 sumed to be a source of strong and sustained directional selection in the wild.

109 The FY region in the Hausa shows evidence of directional selection in two independent properties of t

110 d histone deacetylases have undergone strong directional selection, including a particularly strong s

111 re consistent with the action of positive or directional selection, including an 18-fold enrichment o

112 lly, the false-discovery rate is higher when directional selection involves a recessive rather than a

113 Directional selection is a major force driving adaptatio

114 One potential effect of directional selection is an increase in linkage disequil

115 The strongest evidence of directional selection is found in a region of bab2 that

116 ry phenotypes suggest stabilizing selection, directional selection is more commonly reported.

117 consensus among students of speciation that directional selection is the primary cause of speciation

118 Evolutionary theory predicts that directional selection leads to evolutionary change while

119 ecent selection, we find little evidence for directional selection, likely due to low statistical pow

120 selection is how sexual traits under strong directional selection maintain underlying genetic variat

121 oral head breadth show signs of responses to directional selection matching ecogeographic hypotheses,

122 owing a population bottleneck, the signal of directional selection may be hard to detect because many

123 id substitution are attributable to positive directional selection, not to a relaxation of purifying

124 hese parameters and the frequency with which directional selection occurs, the genomic scale over whi

125 owing asymmetric subgenome domestication for directional selection of long fibers.

126 nd some candidate duplicates where positive (directional) selection of beneficial mutations (Ka/Ks >

127 Recurrent directional selection on a partially recombining chromos

128 differential gene expression resulting from directional selection on blood feeding within a polymorp

129 f cichlid trophic evolution is the result of directional selection on chromosomal packages that encod

130 be explained by differences in the effect of directional selection on duplicated homoeologs.

131 of strongly selected deleterious mutations, directional selection on favorable alleles (causing hitc

132 goals were to characterize the signature of directional selection on FY*O in sub-Saharan Africa and

133 under high nutrients, we found evidence for directional selection on leaf number and height, and for

134 We demonstrated significant directional selection on multiple traits across populati

135 Directional selection on parasitoid behaviour in each te

136 Strong directional selection on Pgm-3 in this form, involves wo

137 onary "arms race." This could lead to strong directional selection on RNAi genes, but to date their e

138 We found evidence for across-treatment directional selection on the means for leaf number, flow

139 ion of allelic effects suggests a history of directional selection on the posterior lobe.

140 ariable conditions, which resulted in strong directional selection on thermal performance traits.

141 ycatchers (Ficedula hypoleuca), we show that directional selection on timing of reproduction intensif

142 tudy increased, but recently declined again, directional selection on timing of reproduction showed a

143 Also, our results suggest substantial directional selection on wing size but not shape.

144 Lack of convincing evidence for directional selection or selective sweeps argues against

145 When the population is subject to directional selection or to deleterious mutations, incre

146 r are consistent with stabilizing selection, directional selection, or diversifying selection.

147 tions displaying evidence of diversifying or directional selection, or mutations with a high selectio

148 ne Sry, which also appears to have undergone directional selection over a short evolutionary period.

149 earlier studies concluding that CPP is under directional selection over the climatic gradient of Nort

150 lls can explain how GCs maintain an adequate directional selection pressure over a large range of aff

151 rectional mutation pressure, rather than the directional selection pressure, is mainly responsible fo

152 If a trait has a history of directional selection, QTL effects should be mostly in t

153 lection occurs, the genomic scale over which directional selection reduces levels of linked variation

154 ifferent years, and reversals in the sign of directional selection regularly occurred.

155 wo of the six phages also imposed additional directional selection, resulting in strongly increased r

156 The roles of positive directional selection (selective sweeps) and negative se

157 id sequence of Adh-Twain evolved rapidly via directional selection shortly after it arose.

158 this gene across Africa with no evidence of directional selection suggesting a limited role for knoc

159 genetic variance, there was no indication of directional selection, suggesting instead a history of o

160 ngly variable levels of gene duplication and directional selection that correlate with their function

161 a classic example of a heritable trait under directional selection that does not result in an evoluti

162 s of guppies were subjected to an episode of directional selection that mimicked natural processes.

163 ber of immune-system genes that may be under directional selection (that is, selection favouring chan

164 y heritable variation and are under opposing directional selection, their evolution is constrained by

165 tion greatly, however, and that the apparent directional selection thereby caused can be substantial.

166 investigate the statistical power to detect directional selection through contrasts of DNA variation

167 ciation approach, we characterize signals of directional selection throughout the genome, identifying

168 ly related species could exert strong enough directional selection to cause evolution of these signal

169 ization (NEO-F), in which one copy undergoes directional selection to perform a novel function after

170 rk also challenges the long-standing view of directional selection towards optimal codons, and provid

171 it test for discriminating rejections due to directional selection (true positive) from those due to

172 Simulations of positive directional selection, under parameter values appropriat

173 l framework for the study of stabilizing and directional selection using data from between-species di

174 In O. rufipogon, the recent directional selection was found in the Pi-ta region, whi

175 Directional selection was predicted in part by drought c

176 Directional selection was rejected in three populations

177 lar rates when genes thought to evolve under directional selection were excluded from the analysis.

178 alancing selection, yet data consistent with directional selection were observed at other codons.

179 ncestral and maintained across species under directional selection, whereas the single-locus (superge

180 variation can be used to identify targets of directional selection, which are expected to have reduce

181 implementing a coalescent model of positive directional selection with arbitrary dominance.