ライフサイエンスコーパス: directionally

1 on, which guides the cancer cells to migrate directionally.

2 uronal activity in an opposite manner and bi-directionally.

3 two hexamers that encircle and unwind DNA bi-directionally.

4 cipher chemoattractant gradients and migrate directionally.

5 n catch a ride on the cytoskeleton to travel directionally.

6 Notably, RNAPII at enhancers transcribes bi-directionally a novel class of enhancer RNAs (eRNAs) wit

7 ion in relative growth rate, appears to vary directionally across geographic gradients.

8 ation in metazoa by communicating signals bi-directionally across the plasma membrane.

9 adhesion receptors that transmit signals bi-directionally across the plasma membranes.

10 ions lead to 68% of walkers taking two steps directionally along a three-foothold track.

11 tein production, in which ribosomes move uni-directionally along an mRNA strand, building amino acid

12 nizes cells by hauling packets of components directionally along microtubules.

13 Drp1 oligomers also translocate directionally along mitochondria.

14 rtificial, linear molecular motors that move directionally along polymeric tracks to transport cargoe

15 more than the ability to simply translocate directionally along ss-DNA.

16 In the model, choice variability could be directionally altered through amplification or dampening

17 Serotonin bi-directionally and differentially modulated glutamatergic

18 ws neighboring cells to polarize and migrate directionally and form characteristic chains of cells ca

19 l snapshots of the enzyme cleaving substrate directionally and sequentially from the 5' terminus.

20 ing (macrocycle) is continuously transported directionally around a cyclic molecular track when power

21 ther, the linearized vector and PCR products directionally assemble into a recombinant molecule throu

22 ly, asymmetric die-1 expression controls the directionally asymmetric expression of gustatory recepto

23 lectivity in the retina relies critically on directionally asymmetric GABA release from the dendritic

24 , the rate of movement of CESA particles was directionally asymmetric in mutant lines that exhibited

25 transcription factor die-1 is expressed in a directionally asymmetric manner in the gustatory neuron

26 esponsiveness, one manifestation of which is directionally asymmetric motion visual evoked potentials

27 ovement with a centrifugal bias and, through directionally asymmetric synaptic connections with the d

28 saurid archaeocete skulls are distinctly and directionally asymmetrical.

29 FtsK translocates dsDNA directionally at >5 kb/s, even under strong forces.

30 The FtsK translocase pumps dsDNA directionally at approximately 5 kb/s and facilitates ch

31 zide-polyethylene glycol-dithiol, is used to directionally attach the Fc, or nonbinding region of the

32 ufficient to silence the active VSG gene and directionally attenuate the ES by disruptor of telomeric

33 The nerve growth cone is bi-directionally attracted and repelled by the same cue mol

34 Loss of PINK1 also produced specific, directionally balanced defects in mitochondrial transpor

35 icted to the germinal centre but migrated bi-directionally between dark and light zones.

36 from 4 to 20 bp and, in some cases, leads to directionally biased 3' --> 5' sliding.

37 hybridization and subsequent backcrosses are directionally biased and that the only likely cross betw

38 Here, we describe how such directionally biased data can be used to estimate the ne

39 astrocyte polarization, IF transport becomes directionally biased from the cell center toward the cel

40 ms fibrils through cell contacts and creates directionally biased geometry.

41 unwinding of double-stranded RNA in a 5'-3' directionally biased manner and RNA strand annealing act

42 Further, we found a cell type-specific, directionally biased synaptic plasticity of two major ty

43 During segregation, movement is directionally biased, speed is comparable between origin

44 vidually released MTs and clusters of MTs is directionally biased: motion is directed away from the e

45 ngiogenic sprouting, endothelial "tip cells" directionally branch from existing vessels in response t

46 both primary and cell-line cultures migrated directionally but slowly toward the anode in an electric

47 t C-I bond breaking yielded IPh that rotated directionally by three different angles, with the second

48 any cardiovascular and neural responses that directionally challenge blood pressure regulation, reduc

49 urces of theory to address sustainability in directionally changing social-ecological systems, apply

50 world in which many key process controls are directionally changing?

51 generate a focused cDNA library that was bi-directionally cloned into a transitive RNAi vector that

52 present a rapid, high-efficiency system for directionally cloning PCR-amplified, PCR-mutated, or syn

53 an be broken down into two separate streams, directionally coding for elementary motion and figure mo

54 s at least three nonstructural proteins that directionally complement one another; 3A disrupts the Go

55 P = 9.1 x 10(-3)), while the 1q22 locus was directionally concordant and nominally significant (rs13

56 ed, genome-wide association studies revealed directionally concordant association of rs10749571 with

57 Thus, polarized M2a macrophages drive a directionally concordant expansion of the iTreg-Th17 cel

58 a) concentration due to rs3777392, which was directionally concordant with the OR observed for a simi

59 rm size in serum due to rs2457564, which was directionally concordant with the OR observed in PROMIS

60 Observational and causal estimates were directionally concordant, except for LDL-C.

61 of pure metals for selected wavelengths, and directionally confined waves similar to those found in o

62 The network model was comprised of two uni-directionally connected neuronal populations of spiking

63 This conclusion is supported by an excess of directionally consistent and nominally significant signa

64 ed measures analysis of variance); >90% were directionally consistent and reached nominal significanc

65 dent PMI cohort (n=15; P<2.30E-4); >85% were directionally consistent and reached nominal significanc

66 total n = 2,579), and the influence remained directionally consistent and significant (p = 0.007).

67 These two loci also yielded directionally consistent associations in a previous meta

68 The meta-analysis showed directionally consistent associations with BMI for all 1

69 59816 (HNF1A), and rs11206510 (PCSK9) showed directionally consistent associations with CHD in the 3

70 sus quartile 1 of the multi-SNP score showed directionally consistent associations with the hypothesi

71 6 previously established BMI variants showed directionally consistent effect estimates in our GWAS (b

72 Cangrelor resulted in directionally consistent effects on the primary end poin

73 ems of the Earth's vegetated surface through directionally consistent influence on vegetation greenne

74 grel compared with those of clopidogrel were directionally consistent regardless of aspirin dose, alt

75 The remaining horses shifted from a faster, directionally consistent response with the symmetric bar

76 trends with anthropometric traits that were directionally consistent with earlier reports in adults.

77 onfidence interval: 4.56 to 7.49), which was directionally consistent with previous observations.

78 In addition, associations of 14 loci are directionally consistent with previous reports.

79 o biases in perceptual choices, which can be directionally controlled through non-invasive brain stim

80 n (BF) to the lateral habenula (lHb) that bi-directionally controls the valence of aggressive interac

81 le -880Delta to increase NPY expression were directionally coordinate in vivo (on human traits) and i

82 two metabolic fluxes, v(1) and v(2), are (1) directionally coupled, if a non-zero flux for v(1) impli

83 with the weakness in stroke survivors being directionally dependent (P < 0.01).

84 The reflectivity of HFL was directionally dependent and increased with eccentricity

85 inducible by electric field stimulation with directionally dependent electrical excitation thresholds

86 We attribute this in part to directionally dependent group velocities of optical phon

87 conductance data with modeling, we show that directionally dependent magnitude differences, not tempo

88 rain regulates EMT in a strain magnitude and directionally dependent manner.

89 red muscle activation patterns contribute to directionally dependent weakness following stroke.

90 nsformations in a two-dimensional system are directionally dependent, and confer pronounced plasticit

91 The effect was also directionally dependent, where cyclic strain applied ort

92 hermore, these changes were greater than, or directionally different from, the breath-hold/airflow co

93 ipoles that create an environment favoring a directionally discontinuous channel hydrogen-bonded wate

94 Adult height has shown directionally diverse associations with several age-rela

95 lar machines, the macrocycle distribution is directionally driven away from its equilibrium value wit

96 Endothelial cells (ECs) migrate directionally during angiogenesis and wound healing by p

97 igin of replication (oriP) is transcribed bi-directionally during reactivation and that both leftward

98 zed in a porous matrix, and the proteins are directionally eluted from the beads and captured on a me

99 ck DV ordering along the LM tectal axis, but directionally extend interstitial branches that establis

100 Although directionally favorable, denosumab was not statistically

101 In the hypha, cytoplasm flows directionally from cell to cell through septal pores.

102 migrate actively in the allantois, and move directionally from the allantois into the proximal epibl

103 Trypanosoma brucei undergoes cytokinesis uni-directionally from the anterior tip of the new flagellum

104 experiments demonstrated that HP1 spread bi-directionally from the tethering site and associated wit

105 nates from vertically porous structures from directionally grown ice crystals and simultaneously indu

106 eudopodial branching is locally regulated to directionally guide angiogenesis.

107 Acanthamoeba move directionally in a three-dimensional (3D) agar system as

108 genomic lagging strand mismatches occurs bi-directionally in E. coli and that, while all MutS-recogn

109 Acanthamoeba trophozoites move directionally in response to an EF in a two-dimensional

110 at random in the absence of an EF, but move directionally in response to an EF.

111 ection of chemoattractant gradients and move directionally in response to bacterial infections and ti

112 nce, little is known about how cells migrate directionally in response to traveling waves.

113 nd Dictyostelium discoideum, orient and move directionally in very shallow chemical gradients.

114 linker with two flanking priming sites to bi-directionally initiate the primer-extension reactions to

115 y complementary oligonucleotides are ligated directionally into a zero background BsaI/ccdB-based exp

116 Upon injury, keratinocytes migrate directionally into the wound bed to initiate re-epitheli

117 Keratinocytes migrate directionally into the wound bed to initiate re-epitheli

118 rain registers visual and auditory inputs to directionally localize an interesting environmental feat

119 nylbutyrate versus NaPBA, NH3 -AUC0-24hr was directionally lower on glycerol phenylbutyrate in each s

120 neutral with respect to HDL cholesterol, and directionally lowered the ratio of total to HDL choleste

121 In vitro, they can mobilize nucleosomes bi-directionally, making it difficult to envision how they

122 Adaptation enables eukaryotic cells to directionally migrate over a large dynamic range of chem

123 of GMFbeta disrupted the ability of cells to directionally migrate to a gradient of fibronectin (hapt

124 Here, we show that planarian stem cells directionally migrate to amputation sites during regener

125 sion, resulting in a failure of monocytes to directionally migrate toward CXCL12.

126 beta contributes to cellular polarization in directionally migrating cells via effects on Rho GTPase

127 mmetric front-rear Cdc42-GTP distribution in directionally migrating cells.

128 ling signaling events at the leading edge of directionally migrating cells.

129 Given that activity bi-directionally modifies synaptic levels of PSD-95, our fi

130 sensitive period during which DA and 5-HT bi-directionally modulate adult aggression.

131 sed using viral-mediated gene transfer to bi-directionally modulate AMPAR activity in the NAc core.

132 enous expression of SNX26 was shown to be bi-directionally modulated by neuronal activity.

133 ms delayed relative to the hippocampus, with directionally modulated grid cells and forward replay ex

134 show that the preferred firing directions of directionally modulated grid cells in rat entorhinal cor

135 We also find that the strength of LE is bi-directionally modulated, in a homeostatic manner, by sni

136 t zebrafish are highly sensitive to drugs bi-directionally modulating brain monoamines, generally par

137 e alphav integrin to migrate efficiently and directionally on CAF-derived matrices.

138 e demonstrate that CV membranes also move bi-directionally on microtubules between the cortex and the

139 of secretory vesicle fusion and re-assembled directionally on vesicle membranes.

140 omosomes can exert focal, nonoverlapping and directionally opposed influences on CT asymmetry within

141 Under conditions of ischaemia, there is a directionally opposite autonomic response with a signifi

142 ditions of myocardial ischaemia, there was a directionally opposite cardiac autonomic response with a

143 Concurrent directionally opposite changes in infarcted and noninfar

144 , it has not been possible to define serial, directionally opposite changes in resorption of infarcte

145 e loci show sex-divergent effects, including directionally opposite effects between sexes at the SIM1

146 mimic or antagomir oligonucleotides yielded directionally opposite effects on contraction rate in pr

147 overexpression of wild-type sorcin displayed directionally opposite effects on L-type Ca2+ channel fu

148 ate 2 populations of single units exhibiting directionally opposite firing when atrial pressure is pe

149 al acoustic changes and/or changes that were directionally opposite to treatment responders.

150 he patients the change in PAWP and E/e' were directionally opposite.

151 ariance determines if phenotypes will evolve directionally or whether they reside at an evolutionary

152 These antibodies were directionally orientated as receptors by thin film depos

153 y, divisions and migration were primarily bi-directionally oriented along the ghost fiber longitudina

154 which serve as hydrogen-bond acceptor sites, directionally orienting the hydrogen atoms of the interf

155 n order to exert traction forces on and move directionally over the dermis.

156 s the paired genes into three categories (co-directionally-paired genes or CDPGs, convergently-paired

157 sotropic wetting on one-dimensional (1D) and directionally patterned surfaces, as well as the technic

158 ne secretion of exosomes powerfully promotes directionally persistent and effective cell motility by

159 exosomes from late endosomes is required for directionally persistent and efficient in vivo movement

160 Our results suggest that vinculin promotes directionally persistent cell migration and tension-depe

161 Further, directionally persistent cell migration was inhibited su

162 agamma effectors in the pathways controlling directionally persistent motility.

163 to stabilize forward-directed protrusion and directionally persistent movement.

164 All RINs then transition to a less directionally persistent multipolar phase of migration.

165 tribution of step lengths, 2) motion that is directionally persistent over short time scales, and 3)

166 Later in infection, motility is faster and directionally persistent, resulting in long, straight ac

167 rns of migration are intrinsically random or directionally persistent.

168 roblasts and epithelial cells from random to directionally persistent.

169 nanocrawler, which reversibly moves along a directionally polar complementary road controlled by aff

170 leads to a chemically ratcheted walk along a directionally polar DNA track.

171 either an N- or a C-terminal alkylamine for directionally preferred peptide immobilization.

172 sence of ClpP ClpA translocates polypeptides directionally, processively and in discrete steps simila

173 other modulating this binding, can transform directionally random DNA fluctuations into directed moti

174 Thus, Egr1 and REST can bi-directionally regulate Ca(V)3.2 promoter activity and mR

175 NR1 phosphorylation was bi-directionally regulated after DFP in striatum versus hip

176 ing the phase of hormone repression, of a bi-directionally regulated hormone target gene, and provide

177 he only phage integrase system available for directionally regulated site-specific DNA integration in

178 We found that synaptic activity bi-directionally regulates neuronal Tet3 expression.

179 n is confined to cytolytic granules that are directionally released following target cell recognition

180 otion that are kinetically captured and then directionally released.

181 e association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic gr

182 inar cells, which function to synthesize and directionally secrete digestive enzymes into a central l

183 ess responses, and most were associated with directionally selected traits, which may have been an ad

184 uption of viral compartment is transient and directionally selected.

185 ned from 75 IC neurons could be described as directionally selective (423, 63%), hemifield (220, 32%)

186 een thought to contain two distinct types of directionally selective (DS) ganglion cell: a bistratifi

187 The excitatory and inhibitory inputs to directionally selective (DS) ganglion cells are themselv

188 SACs exhibit opposite polarity, directionally selective (DS) light responses, depolarizi

189 graphic distribution of synaptic inputs to a directionally selective (DS) rabbit retinal ganglion cel

190 (BT), brisk-sustained (BS), local edge (LE), directionally selective (DS)], comparing small vs. large

191 We then used this strategy to create directionally selective ablations of three distinct path

192 Drosophila, the T4 cells of the medulla are directionally selective and necessary for ON motion beha

193 ng, we found that these neuron types are not directionally selective and that selectivity arises in t

194 sectors of the starburst dendritic field are directionally selective by virtue of a mutually inhibito

195 To address this issue, we recorded from directionally selective cells in visual area MT of monke

196 The ON-OFF directionally selective cells of the retina respond pref

197 another such that the number of neurons with directionally selective curves progressively increased a

198 r pathways, whose selective damage may cause directionally selective eye movement disorders.

199 These results reveal that directionally selective fMRI patterns in motor system ar

200 Directionally selective fMRI patterns in PPC, however, w

201 tion, thereby demonstrating the existence of directionally selective fMRI patterns within each stage

202 ic arm also receives local inhibitory inputs directionally selective for inward motion opposing the e

203 in the population of superior coding ON-OFF directionally selective ganglion cells (DSGCs) genetical

204 l and global forms of inhibition controlling directionally selective ganglion cells (DSGCs) in the ma

205 e, we present evidence for a third strategy: directionally selective ganglion cells (DSGCs) in the mo

206 lay a predictable, causal role in-generating directionally selective hippocampal responses.

207 neurons in area MT, which depend in turn on directionally selective inputs from area V1.

208 Recent evidence indicates that directionally selective light responses occur first in t

209 ompartments, respectively, and underlies the directionally selective light responses of the dendrites

210 ely, and greatly reduced or eliminated their directionally selective light responses.

211 ry systematically with stimulus direction in directionally selective middle temporal (MT) neurons, le

212 R6, express glutamate immunoreactivity as do directionally selective motion-sensitive tangential neur

213 levels and the temporal tuning of the first directionally selective neuron in the ON motion pathway

214 he first robust evidence for the presence of directionally selective neuronal populations in human pr

215 odulation acts directly on the inputs to the directionally selective neurons and supports efficient n

216 to record and manipulate all major inputs to directionally selective neurons in Drosophila.

217 Directionally selective responses in these RGCs were sub

218 eration of directional selectivity in ON-OFF directionally selective retinal ganglion cells (DS RGCs)

219 oubt on earlier assumptions that PI provides directionally selective signals to MT and instead sugges

220 In the fly visual system, directionally selective small-field neurons called T4 an

221 Most of the recorded units were directionally selective.

222 indicating that the presynaptic neurons were directionally selective.

223 xcitatory input to the LGMD is intrinsically directionally selective.

224 -modulated sweeps at that intensity and were directionally selective.

225 selective (DS) ganglion cells are themselves directionally selective.

226 entricity from near the center of gaze, with directionally selectivity tuned in a Gaussian manner.

227 e modality specific (odor > tone attention), directionally sensitive (forward > backward connections)

228 hat the observed head-orientation coding and directionally sensitive cells are essential components o

229 racellular signal but responds by initiating directionally sensitive migration to a persistent signal

230 s are ATP-dependent machines responsible for directionally shifting nucleosomes along DNA.

231 Directionally similar effects were observed for the abov

232 anolazine in patients with BNP >80 pg/ml was directionally similar for recurrent ischemia (HR: 0.78;

233 This change is directionally similar to the androgen-induced lipolytic

234 Directionally similar, but smaller and nonsignificant, t

235 onses measured by many of the techniques are directionally similar, in others they are divergent.

236 Directionally, similar results were also seen with Ad-PL

237 stals, but rather arrays of simple particles directionally sintered into porous sheets.

238 he first time, fine and equiaxed crystals in directionally solidified Al-10Si braze alloy.

239 a hypereutectic Al-40 wt.%Cu alloy has been directionally solidified under various axial magnetic fi

240 e movements, and that this interaction has a directionally specific component.

241 rom stromal-specific FGF7 and FGF10 delivers directionally specific instruction from stroma to epithe

242 unwinding duplex DNA in an ATP-dependent and directionally specific manner and play essential roles i

243 ses in a systematic, temporally precise, and directionally specific manner to generate depth-sign sel

244 gain of responses of neurons in area MT in a directionally specific manner to generate selectivity fo

245 l PMd more than controls in order to perform directionally specific movements before training.

246 sses proceed under mild conditions, with the directionally specific nature of mechanical forces provi

247 These results demonstrate a directionally specific paracrine signaling from epitheli

248 of a motor task, consisting of repetition of directionally specific voluntary thumb movements, before

249 helial-to-stromal communication that also is directionally specific.

250 involved in initially polarizing cells, Sdf1 directionally stabilizes cell protrusions promoted by ce

251 proteolytic component ClpP, processively and directionally steps along the polypeptide backbone with

252 replication origins and later 'migrated' bi-directionally, suggesting that ssDNA formation is associ

253 Previously, we showed that RepD recruits directionally the PcrA helicase to the pC221 oriD, remai

254 both neuronal populations were connected bi-directionally, the relative alpha phase determined the d

255 pbeta) family use RanGTP to transport cargos directionally through the nuclear pore complex (NPC).

256 temperature and that composition is changing directionally through time, potentially in response to c

257 the roof plate boundary organiser signals bi-directionally to acutely coordinate the development of a

258 ns, the growth cones, navigate by responding directionally to guidance cues that pattern the embryoni

259 ots possess the ability to sense and respond directionally to other chemical and physical stimuli, se

260 We find that body size evolved directionally toward phyletic giantism an order of magni

261 CD4 single positive (SP) thymocytes migrated directionally toward the medulla, where they accumulated

262 for neuronal guidance, in which axons extend directionally toward their target tissues.

263 motility or the ability of cells to migrate directionally towards a cocktail of chemoattractants.

264 ere a linear assembly of tumor cells migrate directionally towards blood vessels on fibronectin-colla

265 ex formation initiate at the PAM and proceed directionally towards the distal end of the target seque

266 s remaining in the midline no longer migrate directionally towards the genital ridges, but instead ra

267 Two different MMM grew directionally towards the LECs, whereas non-metastatic m

268 Hexanucleotide repeat expansion in the bi-directionally transcribed C9orf72 gene is the most frequ

269 We investigated the bi-directionally transcribed Na/phosphate cotransporter gen

270 Recent studies have identified bi-directionally transcribed RNAs emanating from these enha

271 we showed that the entire D4Z4 repeat is bi-directionally transcribed with the generation of small s

272 hat the heme-bound form of IsdX1 rapidly and directionally transfers heme to IsdC, a NEAT protein cov

273 H) protein harboring a NEAT domain binds and directionally transfers heme to the Isd system via the c

274 cells, predicting that Usher proteins may be directionally transported as complexes in hair cells and

275 sisting of motor and regulatory proteins are directionally transported down the axis of a cell at con

276 ation ratchet in which the macrocycle can be directionally transported in either direction along an a

277 tiary amine gradient, anionic molecules were directionally transported up to several millimeters.

278 redox-mediated, disulfide-exchange reaction directionally transports the bipedal molecules away from

279 alls of the apparatus, the HD cells remained directionally tuned as if the walls were an extension of

280 uronal activity in the frontal eye field was directionally tuned before both primary and secondary sa

281 The distribution of directionally tuned cells in these dimensions was nonuni

282 on result from shifts in the balance between directionally tuned excitation and inhibition mediated b

283 how direction selectivity is implemented by directionally tuned excitatory and inhibitory mechanisms

284 r (NMDAR) conductances in DSGC dendrites and directionally tuned inhibition provided by the upstream

285 We found that, even without directionally tuned inhibition, direction selectivity ca

286 ms (e.g., maximum likelihood) that read from directionally tuned mechanisms near the end of the motio

287 be driven by inhibitory interactions between directionally tuned motion detectors.

288 The inhibitory inputs onto DSGCs are directionally tuned to the antipreferred (null) directio

289 ion at the first harmonic frequency and were directionally tuned.

290 the nucleosome can unwrap asymmetrically and directionally under force.

291 ermines whether the macrocyclic products are directionally uniform or scrambled.

292 nucleus prepositus caused HD cells to become directionally unstable under dark conditions without aff

293 y composed of two distinct components: (1) a directionally untuned component, which appears to play t

294 eading population of cells that moves highly directionally, while cells behind this group are undirec

295 to efficiently capture and push microtubules directionally with leading plus ends.

296 e invasion in gradient hydrogels occurred bi-directionally with sprout alignment observed in the dire

297 has a class 17 myosin motor domain, moves bi-directionally, with myosin-5 and kinesin-1 cooperating i

298 nt to transcription initiation site slide bi-directionally, with the third nucleosome remaining at th

299 that MAPs with asymmetric friction can move directionally within actively moving microtubule pairs t

300 , including pseudorabies virus (PRV), spread directionally within the nervous systems of their mammal