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1 the affinity of outer arm dynein for Lis1 is directly modulated.
2 or the 4-Gbit/s link, a green laser diode is directly modulated.
3 results demonstrate that commensal bacteria directly modulate a critical control point of the ubiqui
4 of its host gene, dE2f1, upon DNA damage by directly modulating a dE2F1-dependent apoptotic transcri
5 ed on-off-keyed telecommunication signals by directly modulating a semiconductor laser's drive curren
8 e for a specific small heat shock protein in directly modulating actin thin filament length in cardia
9 ative compensatory system that could thereby directly modulate activity in motor circuits to attenuat
13 BCL6 validated targets, miR-155 and miR-361 directly modulate AID expression, indicating that via re
14 dy was to investigate whether tiotropium can directly modulate airway sensory nerve activity and ther
15 ndings suggest that DJ-1 may not function to directly modulate alpha-syn nor does DJ-1 appear to play
16 populations and the use of such tetramers to directly modulate an Ag-specific T cell response in vivo
20 s in epithelial cells of the collecting duct directly modulate aquaporin-2 levels and contribute to t
22 ent activation by the vocal motor system can directly modulate auditory sensitivity to self-generated
26 o investigate the potential for androgens to directly modulate bone resorption, we have examined avia
27 an effect as processors of computations that directly modulate both pre- and postsynaptic neurotransm
28 ch posits that top-down beta-band influences directly modulate bottom-up gamma band influences via cr
31 enes controlled by T-box riboswitches can be directly modulated by commonly used protein synthesis in
33 cell CO2 and ABA signal transduction are not directly modulated by guard cell photosynthesis/electron
34 us during successful associative binding was directly modulated by increases in spatial and temporal
37 lease at excitatory hippocampal synapses are directly modulated by Kv1 channel complexes predominantl
39 strating that extracellular Abeta levels are directly modulated by neuronal and synaptic activity.
41 se results therefore indicate that Kir2.3 is directly modulated by PKC phosphorylation of its channel
42 e show that the migration of GnRH neurons is directly modulated by Slit2 and Robo3, members of the ax
43 enes, suggesting that these genes either are directly modulated by the degree of epileptic activity o
44 r potency and uptake into bacterial cells is directly modulated by the length of the bridging linker,
47 entral nervous system (CNS) are likely to be directly modulated by the same metabolic pathways that r
51 establish that water molecular diffusion is directly modulated by underlying neuronal activity using
58 provide mechanistic insight into how oxygen directly modulates cardiac contractility and suggest tha
59 the finding that restoring CREB activity by directly modulating CBP levels in the brains of adult mi
60 e results thus suggest that PcG proteins can directly modulate cell growth in Drosophila, in part by
61 ussion of the role of activated protein C in directly modulating cell system biology, independent of
62 pectrum of differentially sialylated Nav can directly modulate channel gating, thereby impacting card
63 gulated canonical Wnt/beta-catenin signaling directly modulated chromatin structures of both MyoD and
64 chain fatty acids, but not hydrogen sulfide, directly modulate circadian clock gene expression within
65 ithin a different region of the hairpin that directly modulate cleavage rates, providing a modular as
67 These results demonstrate that ethanol can directly modulate cytoplasmic calcium levels in hypothal
70 e and show that the local tissue environment directly modulates DNA methylation patterns in normal di
71 it remains unknown whether 5-HT2B receptors directly modulate dopaminergic activity and the possible
72 pt that phosphorylation of the KCNQ1 subunit directly modulates drug access to a binding site on the
74 hat activation of the hexosamine pathway may directly modulate early postreceptor insulin signal tran
75 dings highlight an unexpected role for CR in directly modulating effectors such as Ca(v)2.1, which ma
78 we explored the possibility that rhAPC might directly modulate endothelial function, independent of i
84 tor endothelial cell shear stress levels and directly modulate expression of an atheroprotective tran
86 to investigate whether FGFR-3 signaling can directly modulate expression of Paneth cell differentiat
89 d bone morphogenetic protein-15 (BMP-15) can directly modulate follicle-stimulating hormone (FSH) act
90 ed CD11c(+) populations express IL-1beta and directly modulate FRC function to help promote the initi
92 To further test the hypothesis that IL15 directly modulates GABA turnover by reuptake mechanisms,
94 , we assessed the efficacy of one agent that directly modulates GABAergic signaling (baclofen) and on
95 between estrogen state and cortical BDNF: By directly modulating GABAergic interneurons, estrogen may
97 ization of nicastrin and APH-1, but does not directly modulate gamma-secretase processing of APP and
98 ay be attributed in part to their ability to directly modulate gene expression in kidney mesangial ce
100 demonstrate that Dectin-1 signaling can also directly modulate gene expression via activation of NFAT
102 so regulate broad physiological processes by directly modulating gene expression in Metazoa, the regu
105 t, plasma-based optical modulator, which can directly modulate high-power lasers with intensity up to
108 generation via serotonin receptor activation directly modulated hyperpolarization-activated cation ch
109 Our findings demonstrate that insulin can directly modulate hypothalamic neurons that regulate the
112 evidence demonstrates that acetylcholine can directly modulate immune function in peripheral tissues
113 terals from premotor rubrospinal neurons can directly modulate IN output independent of Purkinje cell
116 e extracellular matrix in response to injury directly modulate inflammation and consequently the prom
117 L-arginine/NO pathway in mesangial cells, by directly modulating iNOS expression and NO production, w
119 be exploited in a clinical setting either to directly modulate intrinsic exocytotic mechanisms or to
122 lon and sterols, suggesting that sterols may directly modulate its function by hampering binding of a
124 factor eIF5 is an important partner of eIF2, directly modulating its function in several critical ste
126 d to testable hypotheses that ubiquitination directly modulates kinase activity, and that ubiquitinat
128 hat several inhibitors of the Wnt/Wg pathway directly modulate LEF-1-beta-cat activity on chromatin.
129 studies show advantages for the use of many directly modulated light sources positioned at the trans
130 development and that platelet CLEC-2 and Syk directly modulate lymphatic endothelial cell behavior in
132 so exhibit a channel mode of conduction that directly modulates membrane potential and neuronal funct
133 ons suggest that merlin S518 phosphorylation directly modulates merlin intramolecular and intermolecu
141 et mechanisms whereby intracellular Ca2+ may directly modulate Na channel function have yet to be ide
143 Within the CNS of vertebrates, estrogens can directly modulate neural circuits that govern a wide ran
145 e feeding of KYNA and 3-HK to HD model flies directly modulates neurodegeneration, underscoring the c
148 expression response, a long-term effect, and directly modulate neuronal ion channels including sodium
149 we show that the long non-coding RNA, NEAT1, directly modulates neuronal excitability and is associat
152 his study it was tested whether high glucose directly modulates NO synthesis by rat mesangial cells i
153 fects seen with ketamine at least in part by directly modulating NR2B-containing NMDARs in the MPFC.
155 phosphorylation of the substrate is used to directly modulate nuclear import and export, thereby reg
156 lational modifications have the potential to directly modulate nucleosome structure and consequently
158 saccadic choices perceptual information may directly modulate ongoing saccadic plans, and this proce
159 B. anthracis, a pXO1 plasmid-encoded protein directly modulates or indirectly regulates the transcrip
160 summary, these results suggest that miR-298 directly modulates P-gp expression and is associated wit
163 a previously unappreciated role for Socs1 in directly modulating p53 activity and the DNA damage resp
165 ranscriptional profiling, we show that rhAPC directly modulates patterns of endothelial cell gene exp
169 ons as an instructive retrograde signal that directly modulates presynaptic transmitter release.
170 in the neck-linker length has been shown to directly modulate processivity in different kinesin fami
171 lations were dependent on CD25 itself, which directly modulated proliferation and cytokine responses.
173 modifications regulate physiology either by directly modulating protein function or by impacting imm
175 demonstration of HPSDS in the mid-IR using a directly modulated quantum cascade laser for the measure
177 ownstream effector of that activation, cGMP, directly modulates responses and sensitization of mechan
180 cular switch' during rod-cell development by directly modulating rod-specific genes while simultaneou
182 Here we use optical injection locking of directly modulated semiconductor lasers to generate comp
183 demonstrating that mitochondrial metabolism directly modulates sensitivity of tumour cells to apopto
184 that internal physiology can selectively and directly modulate sensory input to produce state-specifi
185 by changes in gene expression, steroids can directly modulate several transmitter-gated and voltage-
186 s NK1 receptors, suggesting that MOR ligands directly modulate SP-induced nociceptive responses prima
188 These findings suggest that estrogen can directly modulate specific OT and AVP systems through an
189 ling complex core with VHA-B1 and RPT5B that directly modulates specific target gene transcription in
190 ns in the rostral ventromedial medulla (RVM) directly modulates spinal nociceptive transmission by pr
192 ble gene in cardiac muscle cells and that it directly modulates stress-induced gp130 cytokine recepto
196 dental caries pathogen Streptococcus mutans directly modulates target mRNA (gbpC) stability through
199 H3 and H4, but not those of H2A and/or H2B, directly modulate the ability of TFIIIA to bind nucleoso
200 kidney tubulogenesis, whether PCP effectors directly modulate the actin cytoskeleton in tubulogenesi
201 PCP component required for ciliogenesis can directly modulate the actin cytoskeleton to regulate cel
202 intracellular pathogens have the capacity to directly modulate the activation state of a specific mem
203 ,4,5)P(3)), are signaling molecules that can directly modulate the activity of ion channels, includin
205 ndicating that barosensitive NTS neurons may directly modulate the activity of LC neurons and may ser
206 ar-1, which intrinsically localize, can thus directly modulate the actomyosin dynamics required for b
209 aldehydic products of lipid peroxidation can directly modulate the binding and functional properties
210 by cadmium ions indicated that GrIP does not directly modulate the callose levels induced by the trea
211 P-agarose pull-down assay, EGCG was found to directly modulate the conformation of hsp90 and bind at
212 lic calcium (Ca2+i), suggesting that PKC may directly modulate the coupling of the CaR to intracellul
213 of key clock proteins offer the potential to directly modulate the endogenous circadian rhythm and tr
214 lular activation by Advector infection could directly modulate the endothelial cell (EC) adhesion mol
215 provide the first demonstration that WT1 can directly modulate the expression of a gene involved in c
216 ts demonstrate that ILC excitatory afferents directly modulate the extracellular concentration of dop
217 demonstrated that pyrazinoic acid failed to directly modulate the fatty acid synthase activity catal
219 Aspergillus species, but whether neutrophils directly modulate the function of dendritic cells in thi
221 hormone estradiol has been recently shown to directly modulate the gain of central auditory neurons,
224 ver, it is not clear whether these promoters directly modulate the growth of initiated cells or rathe
226 y thoracic pressure reduction is expected to directly modulate the hydrostatic pressure conditions fo
227 Conversely, stem cells are also able to directly modulate the immune response through the produc
229 L10, or CXCL10 alone, or CCL5 alone does not directly modulate the inflammatory response within the h
230 higher myosin densities suggest that Tm can directly modulate the kinetics of a single myosin XB and
231 o postsynaptic, N-terminal isoforms of SAP97 directly modulate the levels, dynamics, and function of
232 peutic interventions may become available to directly modulate the metabolic response to illness, thu
233 le is known about the neural mechanisms that directly modulate the motivational component of aggressi
234 factors that are downstream of cAMP and that directly modulate the motors responsible for melanosome
235 s not known whether antidepressant drugs can directly modulate the neural processing of affective inf
236 Although evidence exists that T. gondii can directly modulate the NF-kappaB pathway, the parasite-de
238 d mutagenesis, we identify key residues that directly modulate the photochemical properties of RpBphP
239 hanges in the sample potassium concentration directly modulate the potential at the working electrode
241 hocytic choriomeningitis virus infection can directly modulate the ratio of virus-specific effectors
242 w pathway by which complement activation may directly modulate the renal response to immunologic inju
244 motions of the inner TM2 helical bundle that directly modulate the size of the central channel pore.
247 e answered, the finding that Hofmeister ions directly modulate the surface water diffusivity implies
249 erythrocytes with exposed phosphatidylserine directly modulated the phenotype of both murine and huma
250 c localization of TPX2 on mitotic structures directly modulates the activity of Aurora A for spindle
252 ggest that activation of mu-opioid receptors directly modulates the activity of GABAergic neurons thr
253 s indicate that cyclic nucleotide signalling directly modulates the activity of L-type Ca2+ channels
255 essed whether the catecholamine noradrenalin directly modulates the activity of these neurons in mice
256 hat the cytoplasmic C terminus of SUR either directly modulates the affinity of a weak ATP binding si
260 histones, indicating that the H2A N-terminus directly modulates the chromatin fiber likely through in
261 uggest a novel mechanism by which a pathogen directly modulates the cytoskeletal architecture of mamm
262 rst indication that Lis1 or any other factor directly modulates the enzymatic activity of cytoplasmic
264 ork reveals a novel mechanism by which Homer directly modulates the function of its target protein Ry
265 egulation whereby a non-DNA binding cofactor directly modulates the occupancy of a transcription fact
268 Thus, genetic variability in CTGF expression directly modulates the severity of diabetic nephropathy.
271 lar swimming velocity and that this behavior directly modulates the transient nature of clumping.
272 regulation of reversible phosphorylation in directly modulating the activities of circadian transcri
273 tion of specific transcription factors or by directly modulating the activities of mitochondrial pro-
274 by binding a common element in an intron and directly modulating the activity of the transcription ma
275 ever, the potential role of alpha-catenin in directly modulating the adhesive function of individual
276 oorly understood functions in the cytoplasm, directly modulating the apoptotic response at the mitoch
277 ls themselves initiate these interactions by directly modulating the behavior of resting ECs through
279 cate that serotonin stimulates egg laying by directly modulating the functional state of the vulval m
280 s and disuse-induced bone loss treatments by directly modulating the mechanosensing cells in bone.
281 PKC increase Ca(2+)-activated exocytosis by directly modulating the membrane- or cytoskeleton-attach
282 elatively slow phototransduction process and directly modulating the rod voltage or current allowed u
283 y to the site of autoimmunity (as opposed to directly modulating their function per se), and thus pre
285 that the ventral tegmental area (VTA), which directly modulates these areas, is part of this circuitr
286 ed PMN and macrophages confirmed that IL-17A directly modulates these cells and significantly enhance
287 Here, we tested the hypothesis that CD40 directly modulates traits of the metabolic syndrome in d
288 resented here demonstrate that MKK4/SEK1 can directly modulate transcription by phosphorylating RXR,
290 , among divalent metal ions, only Mg(2+) can directly modulate TRPM7/ChaK1 kinase activity in vivo.
291 Renal Klotho controls mineral metabolism by directly modulating tubular reabsorption of phosphate an
292 esults indicate that p53 expression does not directly modulate tumor cell sensitivity to PDT in eithe
296 a mechanism by which binding of HDACs to E7 directly modulates viral replication and identifies E2F2
298 of hormonal vasoprotection by which estrogen directly modulates VSMC expression of factor(s) controll
300 ta suggest a novel mechanism by which miR-24 directly modulates XIAP expression level and consequentl
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