ライフサイエンスコーパス: disaggregate

1 In both cases, the released AgLDL was disaggregated.

2 figures for persons above age 84 years were disaggregated.

3 are protein complexes that help to fold and disaggregate a cell's proteins.

4 To disaggregate a decade of national CVD mortality data for

5 They concluded that NDGA could disaggregate Abeta fibrils into aggregates that were lar

6 Although NDGA failed to disaggregate Abeta protofibrils, it did inhibit direct p

7 ibrils but accelerate aggregation of freshly disaggregated Abeta.

8 a suggest that low dose curcumin effectively disaggregates Abeta as well as prevents fibril and oligo

9 ique ability to hinder the formation of, and disaggregate, Abeta assemblies in vitro (EM experiments)

10 hosphates or oligomers of acidic amino acids disaggregate actin bundles into single filaments.

11 sp70-binding site elicits the Hsp104 protein disaggregating activity that now depends on Strep-Tactin

12 es cerevisiae prions requires Hsp104 protein disaggregating activity, overproducing Hsp104 "cures" ce

13 which is required to unleash Hsp104 protein disaggregating activity.

14 h-resolution immunohistochemical analysis of disaggregated adult canine sinus node preparations.

15 e 8- and 12-14-kDa species were treated with disaggregating agents.

16 d health (MNCH), but no analysis to date has disaggregated aid for newborns.

17 To disaggregate amyloid, several subunits cooperatively eng

18 approach to inhibiting amyloid formation and disaggregating amyloid fibrils.

19 he findings also suggest, however, that more disaggregated analyses are necessary, since beneficial e

20 our time-series cross-sectional dataset for disaggregated analyses.

21 cooperate with the Hsp70 chaperone system to disaggregate and reactivate heat-denatured aggregated pr

22 ration of the DnaK/Hsp70 chaperone system to disaggregate and reactivate insoluble aggregated protein

23 Macrophages can disaggregate and release sequestered aggregated LDL by a

24 mmunity composition as communities gradually disaggregate and the least tolerant species are no longe

25 gomers into fibrils, but is inactive against disaggregated and fibrillar Abeta.

26 n occurs in embryonic ectoderm that has been disaggregated and reaggregated.

27 Ovarian serous adenocarcinomas were disaggregated and subjected to growth conditions selecti

28 y help explain the known ability of soluble, disaggregated antigen to induce a state of B cell tolera

29 onflict relationships using a geographically disaggregated approach.

30 he parental chromosomes in single cells from disaggregated arrested embryos and excluded cells from b

31 ly attached to the surface and progressively disaggregate as shear rate exceeds 6000 s(-1).

32 tes in immature starfish oocytes and becomes disaggregated at the time of its activation during matur

33 Enzymatically disaggregated atrial and ventricular mouse myocytes were

34 n as a dermal analog was seeded with freshly disaggregated autologous keratinocytes and applied to fu

35 enough to keep the whole proteome folded and disaggregated but no higher).

36 rillion of personal health care spending was disaggregated by 155 conditions, age and sex group, and

37 e expectancy gains and deficits were further disaggregated by age and cause of death with demographic

38 ion, existing fibrils of alpha-synuclein are disaggregated by baicalein.

39 crete species on SEC, and they are completed disaggregated by boiling in 1% SDS.

40 Surface air temperature trends are disaggregated by boreal cold (November-April) versus war

41 in the United States from 1996 through 2013, disaggregated by condition, age and sex group, and type

42 shed anthropogenic emissions inventories are disaggregated by gas, sector, country, or final energy f

43 Many did not present data disaggregated by gender.

44 in this population, and an increase in data disaggregated by risk groups.

45 d under-five (under age 5 y) mortality rates disaggregated by sex is complicated by problems with dat

46 related with SUVmax for the whole cohort and disaggregated by sex.

47 These multimers could be disaggregated by sulfhydryl reagents and by dimethylmale

48 l sample bacteria counts for source and HSW, disaggregated by supply type.

49 This pattern was robust when the scores were disaggregated by the 4 conditions (P<.001 to <.05), by c

50 ionships to estimate future health spending, disaggregated by the source of those funds, to identify

51 When fish was disaggregated by types, BDE-99 and summation operatorPBD

52 Ebola household secondary attack rate (SAR), disaggregating by type of exposure (direct contact, no d

53 nt activation in adult skin or assemble from disaggregated cells, they are polyclonal in origin.

54 skin was also measured by direct analysis of disaggregated cells.

55 We find that overproduction of the disaggregating chaperone, Hsp104, increases the frequenc

56 il middle subdomain, the signature domain of disaggregating chaperones.

57 The disaggregated chemokines retained their human immunodefi

58 owever, such data on children are scarce and disaggregated clinical data across all ages in this epid

59 Subsequent analysis on primary disaggregated colorectal tumors show that the antibody r

60 aggregates initially were very unstable and disaggregated completely within 2 min.

61 0) protofibrils prepared in buffer alone and disaggregated completely within 3 min on dilution.

62 ures should be reported together, along with disaggregated data; inequality should be reported alongs

63 r analysis on renters in the private sector, disaggregating data between an intervention group receiv

64 mediate cell recovery after severe stress by disaggregating denatured proteins through a poorly under

65 Hsp104, a hexameric AAA+ ATPase from yeast, disaggregates diverse structures, including stress-induc

66 In the presence of the disaggregating drug these proteins transit the secretory

67 Latent class analysis was applied to 14 disaggregated DSM-III-R symptoms for major depression re

68 ree Hb is an endotoxin-binding protein which disaggregates endotoxin and subsequently increases the b

69 We first developed a highly disaggregated environmentally extended mixed unit input

70 e in comparison to paclitaxel; however, they disaggregated ES-2 tumor spheroids, whereas single drugs

71 severe forms of tuberculosis disease, no age-disaggregated estimates of paediatric tuberculosis morta

72 This report underscores the importance of disaggregating ethnic/racial groups and depression thera

73 Moreover, EGCG is not able to disaggregate existing amyloid fibrils at a phospholipid

74 ilized, but the rate of dephosphorylation of disaggregated FcepsilonRI was comparable in intact and p

75 were as active against aggregated as against disaggregated FcepsilonRI.

76 aggregation (IC(50) = 0.8 microM) as well as disaggregated fibrillar Abeta40 (IC(50) = 1 microM), ind

77 Platelets lacking PI3Kgamma disaggregated following low-dose adenosine diphosphate (

78 multiple levels of breakdown and used it to disaggregate food mixtures into their ingredients so tha

79 therapeutic uses of chemokines implying that disaggregated forms may be necessary for safe clinical i

80 Aggregated and disaggregated forms of hMIP-1alpha, hMIP-1beta, and RANT

81 ontaining aggregates, PrP(res) was partially disaggregated, fractionated by size and analysed by ligh

82 the associated soil moisture on a spatially disaggregated framework.

83 cipants reported the severity of 12 symptoms disaggregated from the nine DSM-III-R criteria for major

84 Single-cell disaggregates from adult C57BL/6 mice were prepared from

85 angerhans cells-like dendritic cells and KC, disaggregated FSDDC were cocultured with primary murine

86 By disaggregating gains in child health in Bangladesh over

87 a unique, biologically consistent, spatially disaggregated global livestock dataset containing inform

88 imated their models after adding measures of disaggregated Graduate Record Examination scores by fiel

89 ces of data and 2.9 billion patient records, disaggregated health care spending in the United States

90 Using observed flowering dates and disaggregating heat-stress impacts, both pre- and postfl

91 pite effective kinase inhibition, H2O2 still disaggregated HSP27, but not alphaB crystallin.

92 Injection of disaggregated human GW39 colon cancer cells into the ham

93 ll set of molecules which have been shown to disaggregate IAPP amyloid fibrils.

94 of IAPP amyloid formation and compounds that disaggregate IAPP amyloid.

95 unseeded amyloid fibril formation as well as disaggregates IAPP amyloid.

96 LPS associated with LBP and BPI(N)-LBP(C) is disaggregated in the presence of CD14.

97 The remaining disaggregated insulin, excluding the toxic reactive spec

98 155 conditions (including cancer, which was disaggregated into 29 conditions).

99 Twelve-month NCS/DSM-III-R disorders were disaggregated into 3.2% severe, 3.2% serious, 8.7% moder

100 f social fears assessed in the survey can be disaggregated into a class characterized largely by spea

101 chedule to calculate payments, with services disaggregated into clinically meaningful categories.

102 mbined immunodeficient (NOD/SCID) mice, were disaggregated into single-cell suspensions and analyzed

103 raphic sleep correlates of depression can be disaggregated into state-independent and partially rever

104 closely to the fraction of beta-cells in the disaggregated islet cell preparation.

105 Single cells from disaggregated islets were individually isolated in a mic

106 by fluorescence-activated cell sorting from disaggregated late blastula- and gastrula-stage sea urch

107 The released disaggregated LDL particles were competent to stimulate

108 se mutations decrease the ability of LptE to disaggregate LPS.

109 GrK disaggregates LPS from micelles and augments LPS-CD14 co

110 LPS transfer protein in the OM translocon by disaggregating LPS during transport to allow for its ins

111 ned cells were detected by flow cytometry in disaggregated lymph node cells from 11 subjects and cons

112 CCR5 was analyzed by flow cytometry in disaggregated lymph node cells from untreated HIV-1-infe

113 Use of TPM to disaggregate melanoma exosomes post electroporation was

114 from yeast, have been engineered to robustly disaggregate misfolded proteins connected with ALS (e.g.

115 erpreted with respect to the target rule for disaggregating misfolded proteins.

116 ins, PrP(Sc) derived from the 87V strain was disaggregated more rapidly than that derived from 22L.

117 RH receptor (CRHR) and c-kit double-positive disaggregated mouse skin mast cells.

118 rotein Rhes, which is known to sumoylate and disaggregate mtHtt.

119 ClpB is a member of a protein-disaggregating multi-chaperone system in Escherichia col

120 om Escherichia coli is a member of a protein-disaggregating multi-chaperone system that also includes

121 this modification, without phosphorylation, disaggregates multimeric HSP27.

122 ce of using population as a linear proxy for disaggregating national- or state-scale emissions.

123 To test the hypothesis that HSV disaggregates ND10 structures and disperses PML to precl

124 in an in vivo skin reconstitution assay with disaggregated neonatal dermal cells.

125 43 occurs in the adult heart or is unique to disaggregated neonatal myocytes that are actively reesta

126 s of action potential parameters in cultured disaggregated neonatal ventricular myocytes from Cx43 -/

127 We disaggregated observed CVD mortality in 1990 and 2013 in

128 asis: the recognition, sorting, folding, and disaggregating of the cell's many different proteins.

129 of cellular stress pathways to help refold, disaggregate or degrade the mutant disease proteins.

130 Disaggregated or fibrillar forms of Abeta42 showed much

131 through which the inhibitor peptides bind to disaggregated or otherwise free Abeta16-22 peptides in s

132 CyP40 was also able to interact with and disaggregate other aggregating proteins that contain pro

133 ther Abeta conformations, such as fibrils or disaggregated peptide; it also differentiates between di

134 mate the prevalence and severity of selected disaggregated physical and biological oral conditions am

135 ore, proteolysis of VWF appears promising to disaggregate platelet-rich thrombi and restore vessel pa

136 1 (NUCB1) prevent hIAPP fibril formation and disaggregate preexisting hIAPP fibrils.

137 event amyloid formation by IAPP and does not disaggregate preformed IAPP amyloid fibrils;, instead, i

138 ), completely inhibited fibril formation and disaggregated preformed fibrils, whereas other polyQ-spe

139 bitor of in vitro IAPP amyloid formation and disaggregates preformed amyloid fibrils derived from IAP

140 wever, past research evidences difficulty in disaggregating prenatal environmental influences from ge

141 ating transcriptomic and proteomic data from disaggregated primary human keratinocytes held in suspen

142 erone system and ClpB/Hsp104 collaboratively disaggregate protein aggregates and reactivate inactive

143 utants were also defective in the ability to disaggregate protein aggregates with ClpB, DnaJ and GrpE

144 Whereas the ability to disaggregate proteins is dependent on the Hsp104 M-domai

145 vitro affinity for PrP or had the ability to disaggregate PrP(Sc) in infected brain homogenates.

146 stimulate converting activity and partially disaggregate PrP(Sc), both scrapie infectivity and conve

147 The sex ratio estimates were used to disaggregate published series of both-sexes mortality ra

148 We observe that the disaggregated Q10 (DQ10) solutions adopt PPII-like and 2

149 s node, isolated canine Purkinje fibers, and disaggregated rabbit sinus node myocytes.

150 ngly, high concentrations of RANTES, but not disaggregated RANTES variants, enhanced infection of cel

151 We found that the known disaggregating role of Met-35 sulfoxide could be capital

152 lpha3beta1 integrin suppresses the growth of disaggregated SCLC cells.

153 Analysis of disaggregated sinus node preparations revealed three pop

154 chaperone that has the remarkable ability to disaggregate stress-damaged proteins.

155 mechanisms of intersubunit collaboration to disaggregate stress-induced aggregates versus amyloid.

156 that Hsp104 hexamers deploy more subunits to disaggregate Sup35 prion strains with more stable "cross

157 ppressed by an HSF1-dependent mechanism that disaggregates TDP-43.

158 elements of the heat-shock chaperone pathway disaggregate the A-bodies.

159 egrades LDL apolipoprotein B sufficiently to disaggregate the aggregated LDL, releasing it from the m

160 General population survey data are used to disaggregate the associations of substance use disorders

161 We were able to disaggregate the data by country and vaccine type, and m

162 Our aim was to disaggregate the effects of cash transfer from those of

163 te, county, local, and point source level to disaggregate the inventory and allocate the spatial and

164 oxidative protein Swollenin, can open up and disaggregate the less-ordered regions of lignocellulosic

165 When applied to Exon arrays, it can further disaggregate the signal between alternative transcripts

166 IV and antiretroviral treatment estimates to disaggregate the WHO paediatric tuberculosis incidence e

167 a surgical cohort of patients with NSCLC and disaggregated the findings by sex.

168 d RML prions to branched polyamines in vitro disaggregated the prion rods, reduced the beta-sheet con

169 Our model disaggregates the costs of regional pollution and NRP ex

170 Herpes simplex virus (HSV) 1 disaggregates the nuclear domain 10 (ND10) nuclear struc

171 h an HSF1-dependent chaperone mechanism that disaggregates the protein.

172 ping Bayesian Gene eXpression (MMBGX), which disaggregates the signal at 'multi-match' probes.

173 craping the biofilm from the coupon surface, disaggregating the clumps, then diluting and plating for

174 Disaggregating the concept of the 'GMO' is a necessary c

175 Disaggregating the data into the JMP sanitation ladder,

176 y after occlusive thrombosis by specifically disaggregating the external layer of occlusive thrombi,

177 The study addresses these issues, disaggregating their overlapping effects.

178 eceptor occupancy in the local coronary bed, disaggregate thrombus in the epicardial artery and micro

179 ed because of lack of large-scale, spatially disaggregated time-series data on antibiotic use and res

180 dization assay on immune cells isolated from disaggregated tissue.

181 the assembly process is reversed and fibrils disaggregate to form stable oligomers, hence acting as a

182 Results are disaggregated to characterize the relationship between g

183 Pluripotent stem cells are disaggregated to single cells and then differentiated in

184 The importance of using the most disaggregated trade data set available when resolving us

185 Health Plan Claims Database, we studied and disaggregated trends in use and in insurance and out-of-

186 s, the current study used multicolor FACS of disaggregated tumor to systematically characterize the f

187 Flow cytometry of disaggregated tumors posttreatment with either liposomes

188 n ex vivo enrichment process against freshly disaggregated tumors to purge the repertoire, in combina

189 These can be disaggregated using purified cdc2-cyclin B1 and polo-lik

190 Although parenchymal amyloid was focally disaggregated, vascular deposits were relatively preserv

191 Climate and the Economy (RICE)-a regionally disaggregated version of the Dynamic Integrated model of

192 onstitution of its RNA binding activity from disaggregated virus-like particles were established.

193 Single-cell aortic disaggregates were prepared from adult chow-fed C57BL/6

194 ed to describe attack occurrence and impact, disaggregated where possible by age, sex, and location.

195 The 60-200 nm globular aggregates disaggregate with an apparent rate constant of approxima

196 severely aggregated endogenous proteins are disaggregated without degradation during recovery from s