ライフサイエンスコーパス: disassembly

1 t S19, S22, S37, and S60, leading to network disassembly.

2 binding of the MCC to the APC/C and for MCC disassembly.

3 service that may be threatened by community disassembly.

4 These results link CK2 activity with SG disassembly.

5 dependent steady state between formation and disassembly.

6 ough crosslink unbinding and and/or filament disassembly.

7 ction dynamics without resulting in junction disassembly.

8 on in fat-laden HepG2 cells and inflammasome disassembly.

9 are both structurally specific and labile to disassembly.

10 supported by controlled microtubule network disassembly.

11 a possible role for hYVH1 in stress granule disassembly.

12 to assess apical domain loss and junctional disassembly.

13 s modulated through dynamic processes of NCP disassembly.

14 vesicle assembly while others regulate coat disassembly.

15 gers an RNP charge inversion, which promotes disassembly.

16 zed SV40, thereby preventing premature viral disassembly.

17 ed curvature of the ring itself promotes its disassembly.

18 f yeast microtubules and induces their rapid disassembly.

19 sion levels, resulting in actin cytoskeleton disassembly.

20 th cones whereas repulsive cues induce actin disassembly.

21 re required for Nap1 to enhance RSC-mediated disassembly.

22 ntally analyzed its pathways of assembly and disassembly.

23 and M47 residues to induce cellular F-actin disassembly.

24 gulatory inputs for kinetochore assembly and disassembly.

25 uring its assembly, catalytic activation and disassembly.

26 ntracellular transport enabling viral capsid disassembly.

27 us saturation levels to control assembly and disassembly.

28 nsity, and the timing of Z-ring assembly and disassembly.

29 as a thermal switch for cluster assembly and disassembly.

30 sses of protein-Ca(2+)-membrane assembly and disassembly.

31 istones are not able to enhance RSC-mediated disassembly.

32 AD51 during presynaptic complex assembly and disassembly.

33 nt stochastic dynamics of their assembly and disassembly.

34 rrow ingression controls microvillar F-actin disassembly.

35 rvature, and ultimately promotes microtubule disassembly.

36 n also changes during flagellar assembly and disassembly.

37 ll as in genes controlling ECM structure and disassembly.

38 and facilitates their premature post-stress disassembly.

39 hydrolysis triggers filament stiffening upon disassembly.

40 ting a catalyzed cycle of SNARE assembly and disassembly.

41 aberrant nephrin turnover and slit diaphragm disassembly.

42 irectly amplify Mical Redox-mediated F-actin disassembly.

43 ciples that underlie their self-assembly and disassembly.

44 AD52 during presynaptic complex assembly and disassembly.

45 of SGs as well as their premature or delayed disassembly affect physiology and survival of cells unde

46 s association was abrogated upon microtubule-disassembly agents, resulting in attenuation of capsid f

47 Cumulus cell apoptosis and matrix disassembly also occurred in ovulated COCs cultured in v

48 First experiments initiating (i) partial disassembly and (ii) partial re-assembly after complete

49 i) PI(3)P and PI(4)P are dispensable for the disassembly and activation of (phago)lysosomal soluble N

50 as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during

51 delays, or reverses cardiomyocyte centrosome disassembly and binucleation.

52 rogen resistance 3 (BCAR3) promotes adhesion disassembly and breast tumor cell invasion.

53 p31(comet) and the ATPase TRIP13 promote MCC disassembly and checkpoint silencing.

54 rocess of forming the mature HIV-1 core: the disassembly and de novo reassembly model and the non-dif

55 ncoding the p97/VCP ATPase reduced myofibril disassembly and degradation on denervation or fasting.

56 for elucidating additional aspects of capsid disassembly and HIV-1 uncoating.

57 reveal a new region that regulates reovirus disassembly and how perturbing a metastable capsid can c

58 -mediated destruction of SG mRNA promotes SG disassembly and may also prevent SG assembly.

59 rylate nucleoporin interfaces to promote NPC disassembly and nuclear envelope breakdown.

60 uring M-phase exit in metazoans: kinetochore disassembly and nuclear reassembly.

61 tions to override Snail-dependent junctional disassembly and postpone EMT during Drosophila melanogas

62 ility of TRIM5alpha to induce premature core disassembly and prevent reverse transcription; however,

63 ntral molecule that regulates apoptotic cell disassembly and progression to secondary necrosis, and p

64 , TIA1 mutations delayed stress granule (SG) disassembly and promoted the accumulation of non-dynamic

65 nd in yeast, which couples ATP hydrolysis to disassembly and reactivation of proteins trapped in solu

66 target H2B at multiple stages of nucleosome disassembly and reassembly during transcription.

67 dition to the ubiquitous replication-related disassembly and reassembly of chromatin, H1 is deposited

68 gi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process during each cycle of

69 the aberrant mRNA and polypeptide, ribosome disassembly and recycling.

70 ut not autophagy-defective, NBR1 enhances FA disassembly and reduces FA lifetime during migration.

71 ting signaling pathway amplifies the F-actin disassembly and repulsive effects of a growth-preventing

72 ncomitantly inhibits stress-induced polysome disassembly and SG assembly.

73 while hydrolysis and release promotes helix disassembly and substrate release at the lagging end.

74 This in turn allowed mutational redesign of disassembly and testing in both bacterial and mammalian

75 c traps in the energy landscape of aS fibril disassembly and the presence of transient partially fold

76 understand their mechanisms of assembly and disassembly and their architectures.

77 to the processes of nucleosome assembly and disassembly and thus the fluidity of the ever-changing c

78 may be maintained through repeated rounds of disassembly and tri-snRNP reassociation.

79 Direct observation of TF assembly and disassembly and various biochemical reactions during tra

80 ered departure of SG components during their disassembly and, furthermore, that vhs itself has the ca

81 ity of regulation/signaling, dynamic complex disassembly, and disease mutations in cancer and intelle

82 uncouple TA binding from induced Get3*Get4/5 disassembly, and inhibit the ER targeting of the Get3*TA

83 e in F-actin resulting from slowing of actin disassembly, and the increased Arp2/3 regulator lifetime

84 r growth of organelles, their degradation or disassembly, and their partitioning among daughter cells

85 surrounded by a dynamic shell with assembly, disassembly, and transitions between the core and shell

86 t with species traits to influence community disassembly, and very high extirpation risks in the Sout

87 g in which DNA unwinding and histone protein disassembly are coupled.

88 n and negative regulation of protein complex disassembly are involved in adipocyte regulation.

89 driver of apical constriction and junctional disassembly are periodic pulses of junctional and medial

90 Actin filament assembly and disassembly are vital for cell functions.

91 e results identify enhancer inactivation and disassembly as a mechanism of IFN-gamma-mediated gene re

92 on rather transiently accelerates centrosome disassembly as well as the rate of binucleation.

93 The replisome also coordinates nucleosome disassembly, assembly, and the establishment of sister c

94 dherin endocytosis and pathological junction disassembly associated with the endothelial-derived tumo

95 copolymers that would allow the swelling or disassembly at elevated temperatures with eventual backb

96 an exploration of nanoparticle assembly and disassembly at the interface by controlling parameters s

97 ing that adhesion assembly predominates over disassembly at the leading edge.

98 e end of the helix while hydrolysis promotes disassembly at the other end, so that Vps4 'walks' along

99 tion through chromatin, to induce nucleosome disassembly at transcribing regions during RNAPII transc

100 actin polymerization and junctional protein disassembly, attenuates both early- and late-onset BBB i

101 ounds of pre-initiation complex assembly and disassembly before productive elongation of Pol II is ac

102 l stabilization does not lead to rapid nodal disassembly but to loss of specific nodal components in

103 ant do not prevent arsenite-induced polysome disassembly, but fails to support the SG assembly, sugge

104 ons affect kinetics of tetramer assembly and disassembly, but their effects on tetramerization equili

105 site ( T2: ) that assists in ubiquitin chain disassembly, by binding the UBL of deubiquitinating enzy

106 optosis and associated dynamics of ribosomal disassembly, calcium overload and mitochondrial fission.

107 In both cases, junctional disassembly can be blocked by simultaneous induction of

108 SG formation and, more specifically, that SG disassembly can be driven by vhs endoribonuclease activi

109 binatorially increase Mical-mediated F-actin disassembly, cellular remodeling, and repulsive axon gui

110 hanced disassembly" when combined with actin disassembly co-factors Coronin-1B and actin-interacting

111 se mechanisms enable a dynamic deneddylation-disassembly cycle that promotes rapid remodeling of the

112 all steps of the actin filament assembly and disassembly cycles, as well as the arrangement of actin

113 keletal contractility and adherens junctions disassembly during extravasation and may aid in identifi

114 RL2(Lrr1) as a master regulator of replisome disassembly during vertebrate DNA replication terminatio

115 c residues hypothesized to facilitate trimer disassembly during viral entry.

116 used to study multi-protein complex assembly/disassembly dynamics.

117 planar CA lattice on a substrate and of its disassembly, either spontaneous or induced by materials

118 rvature angles between subunits, followed by disassembly end-products consisting of highly curved oli

119 dentified an interaction between the F-actin-disassembly enzyme Mical and the Abl tyrosine kinase.

120 some, particles undergo a series of stepwise disassembly events.

121 with biochemical estimation of the assembly/disassembly extent, and can provide valuable real-time k

122 Depletion of disassembly factor Prp43 suppresses H2A.Z-mediated splic

123 rexpression of the Arabidopsis clathrin coat disassembly factor, Auxilin2, which inhibits clathrin-me

124 On actin disassembly, fragmented mitochondria undergo rapid fusio

125 erlie the recent findings that the ESCRT-III disassembly function of Vps4 and the microtubule-severin

126 beta-tubulin mutant that dramatically slows disassembly has no effect on work output, indicating an

127 e kinetic study of the template assembly and disassembly, have been investigated in detail.

128 e genome by carrying out nucleosome assembly/disassembly, histone exchange, and nucleosome reposition

129 ation-responsive inactivation and holoenzyme disassembly, illustrating the complexity of regulation/s

130 ore, which triggers the initiation of capsid disassembly.IMPORTANCE For successful infection, the HIV

131 erties of microswimmers through assembly and disassembly in a controlled fluidic environment.

132 polypeptides, which effectively induce actin disassembly in eukaryotic cells.

133 o Mg(2+)- and Ca(2+)-mediated focal adhesion disassembly in metastatic cells, rather than changes in

134 -mediated selective autophagy in enabling FA disassembly in motile cells.

135 Boolean logic and undergo the input-induced disassembly in order to implement the proper output acti

136 psids adopt conformations that undergo rapid disassembly in response to a specific cellular cue.

137 We show that Src mediates VE-cadherin disassembly in response to metastatic melanoma cells.

138 ffectively stabilize the microtubule against disassembly in the absence of a robust GTP cap.

139 Fibre disassembly in the absence of calcium provides a basis f

140 gelsolin, and that gelsolin regulates actin disassembly in the connecting cilium, thus facilitating

141 an activator of the Dhh1 ATPase, prevent PB disassembly in vivo.

142 hibition or PTP opening increased synthasome disassembly in WT, but not in CypD KO heart mitochondria

143 normal dynamics of microtubule assembly and disassembly include many anticancer drugs in clinical us

144 n, Mical oxidation of actin promotes F-actin disassembly independent of the nucleotide-bound state.

145 Early translational recovery and SG disassembly induced by trehalose pretreatment can sensit

146 ntify a succession of transient assembly and disassembly intermediates.

147 glucosylceramide (GluCer), without apparent disassembly into free monomers.

148 Stress granule disassembly is also a stepwise process with shell dissip

149 etermined that stress-induced 26S proteasome disassembly is conserved from yeast to human.

150 Thus, dynamin disassembly is not coupled to GTPase activity, supportin

151 ifetimes (<8 min), suggesting that replisome disassembly is quite prevalent, possibly occurring sever

152 But if organelle assembly or disassembly is regulated by number or size, how would th

153 These results demonstrate that Golgi disassembly is required for mitotic progression because

154 While cilia disassembly is traditionally thought to occur solely thr

155 ciates with chromosomes only after nucleolar disassembly later in prophase.

156 ial cell contractility and adherens junction disassembly leading to endothelial barrier breakdown.

157 UMO1/Ubc9 complex functions as an autonomous disassembly machine with a preference for the export rec

158 on, the LegC/VAMP4 complex avoids the host's disassembly machinery, thus effectively trapping VAMP4 i

159 A basic disassembly mechanism in all eukaryotes depends on solub

160 pe the early endosome through a pH-triggered disassembly mechanism.

161 In particular, a novel disassembly method induced by strain release of the gues

162 ylation program, thereby influencing spindle disassembly, nuclear envelope reformation, and cytokines

163 We eliminate the possibility that the disassembly occurs by the association between mPPCs and

164 te that synaptic dysfunction seen as F-actin disassembly occurs very early, before onset of pathologi

165 Here, we present a simple way to monitor disassembly of (19)F-labeled VLPs derived from bacteriop

166 or based on voltage-controlled self-assembly/disassembly of 16 nm plasmonic nanoparticles at the inte

167 We further found that FA induced the disassembly of 26S immunoproteasomes, but not standard 2

168 NA damage and regulates the dynamic assembly/disassembly of 53BP1 and BRCA1 foci.

169 on is dependent on the dynamic formation and disassembly of actin filament-based structures, includin

170 enitor cells (OPCs) involve the assembly and disassembly of actin microfilaments.

171 VE-cadherin phosphorylation resulting in the disassembly of adherens junctions and opening of the par

172 Although Snail is essential for disassembly of adherens junctions during epithelial-mese

173 tes through reactive oxygen species-mediated disassembly of adherens junctions is pivotal for the acu

174 rc-dependent phosphorylation of VE-cadherin, disassembly of adherens junctions, and EC barrier failur

175 Both assembly and disassembly of amyloids strongly depend on the presence

176 Disassembly of anillin patches was myosin independent, s

177 nt environmental factors on the assembly and disassembly of beta-endorphin amyloids in vitro.

178 CSNK-1 was required for disassembly of both myosin patches and anillin patches.

179 y described role for Epb41l5 in facilitating disassembly of cadherin-dependent AJCs.

180 tion of the histone core during salt-induced disassembly of canonical NCPs.

181 prevents infection by inducing the abortive disassembly of capsid cores recognized by its C-terminal

182 of synapsin is mediated by dynamic assembly/disassembly of cargo complexes followed by short-range v

183 ate and facilitates the dynamic assembly and disassembly of cell-matrix focal adhesions (FAs), which

184 pre-established chromosomes results in rapid disassembly of centromeric regions while most chromatin

185 n for reutilization, but that it may involve disassembly of conjugated ubiquitin to maintain proteaso

186 is a two-phase process involving the initial disassembly of desmin filaments by Trim32, which leads t

187 promoting CDC-48/p97-dependent turnover and disassembly of DNA replication factor complexes.

188 Blocking VEGFA-induced disassembly of endothelial junctions, thereby suppressin

189 rs to be linked to the cycle of assembly and disassembly of ESCRT-III complexes at membranes.

190 driven by ESCRT pathways, which culminate in disassembly of ESCRT-III polymers by the AAA ATPase Vps4

191 migration requires the cyclical assembly and disassembly of focal adhesions.

192 participates in regulating the formation and disassembly of focal adhesions.

193 atous polyposis coli protein is required for disassembly of focal adhesions.

194 Ras/MAPK (Erk1/2) activity by regulating the disassembly of Grb2/Sos1 complexes associated with clath

195 psid-nucleocapsid complexes and promoted the disassembly of HIV-1 capsid (CA) shell.

196 ng a conserved mechanism for recognition and disassembly of HORMA domain-closure motif complexes by T

197 ing and demonstrate the de novo assembly and disassembly of HSP gene foci.

198 This defect causes the premature disassembly of individual Z-rings, leading to the freque

199 on in ectoderm, is sufficient to drive early disassembly of junctions.

200 f tetracycline, Apt leaves CSs, resulting in disassembly of M-shape structure and following the addit

201 that of TRIP13 ATPase promotes the complete disassembly of MCC, necessary for the inactivation of th

202 cally active homooligomers, also promote the disassembly of MCC.

203 Interestingly, disassembly of MFs with cytochalasin D, at early stage o

204 In mitosis, the dynamic assembly and disassembly of microtubules are critical for normal chro

205 a curvature-induced mechanism may operate in disassembly of other contractile networks.

206 Yet, how cells regulate assembly and disassembly of PBs remains poorly understood.

207 pathway coordinates CO designation with the disassembly of SC proteins to ensure accurate chromosome

208 By cooperatively modulating the assembly and disassembly of SGs, ribonucleoprotein condensation can i

209 SET also directed the disassembly of Shugoshins in a polo-like kinase 1-augmen

210 Dynamic assembly/disassembly of signaling complexes are crucial for cellu

211 We investigate the disassembly of single nucleosomes using a predictive coa

212 signing and regulating the self-assembly and disassembly of small molecules, especially for molecular

213 own to have distinct effects on assembly and disassembly of T4P, suggesting that it may function in a

214 The regulation and disassembly of the 100S ribosome are largely unknown bec

215 de secreted hydrolases, suggesting a role in disassembly of the arbuscule and interface.

216 Both self-assembly and disassembly of the CA layer are cooperative reactions th

217 Disassembly of the CA layer showed hysteresis and appear

218 phorylation of RLC-phosphorylated filaments, disassembly of the dephosphorylated filaments to folded

219 ane constriction required for fission, or in disassembly of the dynamin polymer to trigger fission.

220 cells through a mechanism that involves the disassembly of the dystrophin-glycoprotein complex, and

221 leavage at the polyadenylation site triggers disassembly of the elongation complex.

222 e side chains of proteoglycans, resulting in disassembly of the extracellular matrix underlying endot

223 e reversible switched by pH-induced assembly/disassembly of the fibrils into random coils.

224 earance of the charged moieties and leads to disassembly of the formed clusters.

225 Maturation of HIV-1 requires disassembly of the Gag polyprotein lattice, which lines

226 acteria, intrinsic termination signals cause disassembly of the highly stable elongating transcriptio

227 a better understanding of self-assembly and disassembly of the HIV capsid and protein-based two-dime

228 Fenton reactions when photooxidation causes disassembly of the iron-rich photosystems.

229 idized into sulfoxide units, leading to full disassembly of the micelles, as confirmed by detection o

230 microtubule severing, which results in local disassembly of the microtubule cytoskeleton and loss of

231 gradation, but may also affect stability and disassembly of the multimeric complex.

232 f the ester bond on the molecules results in disassembly of the nanofibrils.

233 ill limit depletion, thereby preventing full disassembly of the polymeric calsequestrin network and c

234 f UNC-84 leads to defects in the loading and disassembly of the recombinase RAD-51.

235 and the GINS complex) helicase and triggers disassembly of the replication machinery.

236 ty of LAF-1, suggesting that ATP may promote disassembly of the RNP complex.

237 Although prompt disassembly of the SC during exit from prophase I is a l

238 ase at late pachytene is critical for timely disassembly of the SC proteins from the long arms, and i

239 be essential for the regulated assembly and disassembly of the SC.

240 uaternization of P2VP was shown to cause the disassembly of the superstructures, resulting in the fir

241 crucial to understand how cells use assembly/disassembly of these complexes to control function.

242 The order of assembly and disassembly of these two structures remains unknown.

243 ycles of nucleocytoplasmic transport require disassembly of transport receptor/Ran-GTP complexes in t

244 e mechanism by which TRIM5alpha mediates the disassembly of viral cores is poorly understood.

245 conformational change during the proteolytic disassembly of virions to infectious subvirion particles

246 in a manner that does not involve replisome disassembly or reassembly, albeit with loss of one of th

247 Here, we probe the disassembly, organization and reassembly steps of the AD

248 ntly introduced and unconventional assembly, disassembly, organization, reassembly (ADOR) method repr

249 The assembly-disassembly-organization-reassembly (ADOR) mechanism is

250 The assembly-disassembly-organization-reassembly (ADOR) process has b

251 ites, IPC-9 and IPC-10, through the assembly-disassembly-organization-reassembly mechanism.

252 nstrate continuous monitoring of microtubule disassembly over a 30 min period.

253 and play key roles in chromatin assembly and disassembly pathways.

254 etitive interactions that underlie community disassembly patterns.

255 g and debranching are important steps in the disassembly process generating oligomers as intermediate

256 r cell; however, it is not clear whether the disassembly process per se is important for partitioning

257 odeling into tubulin-like rings and the full disassembly process.

258 of dynamic assemblies via self-assembly and disassembly processes for therapeutics and diagnostics.

259 ve analytical tools to monitor self-assembly/disassembly processes in real-time substantially lags be

260 irst briefly introduce the self-assembly and disassembly processes in the context of cells, which pro

261 A better understanding of community disassembly processes is critical for conserving and res

262 UV-Vis spectroscopy to monitor the assembly/disassembly processes of the basic YES-gate structure th

263 able progress in the last decade, though the disassembly processes remain underexplored.

264 ively modulate the rate of both assembly and disassembly processes.

265 pusher chain shows a cascade of fission (or disassembly) processes as the self-propulsion velocity i

266 el, an assembly promoter, and vinblastine, a disassembly promoter.

267 namic light scattering studies show that the disassembly rate of preformed Abeta fibrils is controlle

268 bly than WT SM alpha-actin, driven by a high disassembly rate.

269 n three distinct virions that have different disassembly rates in infection.

270 oliferation rate-dependent kinetics (average disassembly rates: 6.6+/-0.8% and 3.6+/-0.4% per day in

271 from a simple model, which indicate that the disassembly reaction is first-order in the concentration

272 equential combination of both displacive and disassembly/reassembly processes for HIV-1 maturation.

273 ACT complex, known to be involved in histone disassembly/reassembly, is required for clock function a

274 ular mechanism of NSF-mediated SNARE complex disassembly remained unclear until recently.

275 ocytic trafficking required for virus capsid disassembly remains unclear.

276 characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate.

277 te such negative cellular effects as F-actin disassembly/repulsion.

278 noncovalent guest-host interactions, undergo disassembly (shear-thinning) when injected through a syr

279 We used rheology, disassembly spectrometry, and simulations to measure the

280 on work output, indicating an uncoupling of disassembly speed from protofilament strain.

281 agosomes associate with FAs primarily during disassembly, suggesting autophagy locally facilitates th

282 support, programmed cell death, microtubule disassembly, synaptic function, aging, and insulin resis

283 ough cleavage of talin and FAK, and adhesion disassembly through cleavage of FAK.

284 ially selective processing that allows their disassembly to form perforated platelets, such as well-d

285 ombination of enzyme-instructed assembly and disassembly to target downregulation in cancer cells by

286 l the cellular folding, assembly, unfolding, disassembly, translocation, activation, inactivation, di

287 hat the ability of BCAR3 to promote adhesion disassembly, tumor cell migration and invasion, and Rac1

288 on, can be important regulators of community disassembly under land use change.

289 d that, befitting this ability to promote SG disassembly, vhs is able to localize to SGs.

290 Disassembly was accomplished in a reducing environment,

291 To prevent Golgi disassembly, we expressed HRP linked to a Golgi-resident

292 hat change their fluorescent properties upon disassembly, we observed that serum proteins bind to and

293 chanism of V-ATPase regulation by reversible disassembly, we recently determined a cryo-EM reconstruc

294 e effective than Cof1 in promoting "enhanced disassembly" when combined with actin disassembly co-fac

295 a unique mechanism referred to as reversible disassembly, wherein the soluble catalytic sector, V1, i

296 n can undergo extremely fast (84 subunits/s) disassembly, which depends on F-actin's nucleotide-bound

297 y at the ER/ERGIC interface after outer coat disassembly, which is a prerequisite for fusion with ERG

298 undergo incessant remodeling and assembly or disassembly within seconds.

299 interactions between retinal cell layers, so disassembly would prevent structural coupling between op

300 43_Ntr1GP) is as efficient as the NTR in ILS disassembly, yielding identical dissociation products an