ライフサイエンスコーパス: discern

1 rendering low-frequency clones difficult to discern.

2 dded protein complexes is often difficult to discern.

3 levant information has remained difficult to discern.

4 eir direct substrates are often difficult to discern.

5 e, and the vascular pattern was difficult to discern.

6 terns between roots and shoots are harder to discern.

7 the precise role of mTOR has yet to be fully discerned.

8 ins were either not affected or could not be discerned.

9 pwise co-evolution of MHC class I and KIR is discerned.

10 e(-1) between the HSA-AuNC and bilirubin was discerned.

11 permethylation of the V1 promoter region was discerned.

12 e and no specific infectious agents could be discerned.

13 , when individual ion peaks can no longer be discerned.

14 n and extracellular matrix to Fpassive to be discerned.

15 ost instances, a primary allegation could be discerned.

16 ta-analyses, and no overall pattern could be discerned.

17 as-induced pancreatic neoplasia has not been discerned.

18 mall preponderance of ABAB stacking could be discerned.

19 arious proteins during fibrillation could be discerned.

20 and other non-centrosomal MTOCs has not been discerned.

21 istance, we quantified the cell's ability to discern 8 TNF concentrations at each step of the NF-kapp

22 Here we discern a passive intercellular role of TFP during flage

23 GA, in order to see if one can automatically discern a unique pediatric cluster in the combined data

24 appear to be highly translatable because we discerned an inverse relationship between the expression

25 To confirm target engagement and discern analogues with off-target activity, each compoun

26 elective feature detection that flies use to discern and escape looming threats.

27 esses, endowing the cell with the ability to discern and respond to mechanical cues.

28 ion states of the contact configurations are discerned and further confirmed by comparing individual

29 rated how the closely related lectins can be discerned and quantified in a single assay based on immu

30 nomics results served as "fingerprints" that discerned and revealed the toxicity mechanism at the mol

31 ent stages of the percolation process can be discerned, and these indicate that roads integrate to th

32 the protease exclusion (PE) assay which can discern antagonists of protein-protein interactions in a

33 We were unable to discern any impact of a complementary radio campaign on

34 and demonstrate their differential power to discern ape subspecies and populations.

35 atures predictive of eventual fates could be discerned as early as the first T lymphocyte division an

36 alongside 100 published ones - enable us to discern at least two distinct temporal phases of dispers

37 The current approaches are inadequate to discern between direct versus indirect influences (i.e.,

38 Furthermore, the data allowed us to discern between protein isoforms according to expression

39 Our analysis reveals that these methods discern between random (EF), alternating (EI and EHI), a

40 We further introduce ways to discern between the binding of both ligands to different

41 lication of the Akaike Information Criterion discerning between all-optical analogues of electromagne

42 procedures and often present difficulties in discerning between closely related isoforms, e.g. due to

43 With the aim of discerning between different sugar and sugar alcohols of

44 guide the deployment of the approximations, discerning between innate, model-free, heuristic, and mo

45 Our approach reliably discerns bona fide PAS from false PAS that arise due to

46 eatures of their evolutionary process may be discerned by comparing multiple regions or cells of a tu

47 of broad coordinated trends which cannot be discerned by more targeted assays.

48 h clade, and each member of both clades, was discerned by specific upregulated genes, which can serve

49 Finally, we show that DISCERN can uncover potential mechanisms underlying netw

50 vel statistical denoising algorithm, to help discern cancer perturbations driving most of the variati

51 Discerning cardiac myocyte cell cycle behavior is challe

52 y provide subcellular spatial information or discern cell-to-cell heterogeneity within the bacterial

53 demonstrated evidence of validity and could discern changes in trainees' image acquisition performan

54 tor Imaging of Cell Transitional States), to discern chromatin organizational changes, demarcate line

55 The resulting EIEIO spectra can be used to discern cis and trans double-bond isomers by virtue of t

56 Machine-learning models can discern clinically relevant peripheral oximetry, blood p

57 , demonstrating a transwell platform able to discern collective or individual cellular invasion.

58 is reversible and can be followed by easy-to-discern color changes.

59 Such discerning communication may contribute to folding event

60 ce but persistent members of the microbiota, discerning community and host factors that influence the

61 study highlights the fact that patients are discerning consumers of interpreter services; and could

62 the exosome proteome due to the challenge of discerning contaminant proteins that may be identified v

63 Efforts to discern degradation signals of misfolded proteasome subs

64 se datasets for subsequent analyses, such as discerning deletion types or detecting driver aberration

65 utilized advanced fluorescence microscopy to discern details on the mobility and self-assembly of Anx

66 ch outcome measure, if any, was best able to discern differences among treatment groups.

67 To discern differences in genetic risk factors for PsA and

68 and human subjects with T1D were examined to discern differences in SC density and functionality comp

69 thogens transmit across landscapes; however, discerning different transmission routes is challenging.

70 We present a computational framework, called DISCERN (DIfferential SparsE Regulatory Network), to ide

71 resentatives early in development could help discern discordance among stakeholder priorities; facili

72 lity of applying a network-based approach to discern disease subtypes from comorbidity data recorded

73 (sgRNAs) between populations, which does not discern distinct phenotypes and editing outcomes generat

74 Using MDE we are able to discern driving effects in the occipital module between

75 severe asthma exacerbations and can serve to discern driving mechanisms and promote the development o

76 repair has remained unclear and difficult to discern due to the phosphorylation and degradation of p3

77 We used in silico methods to discern dynamic inflammatory networks that could disting

78 etest reliability, four cingulate subregions discerning e.g., pregenual ACC (pgACC) from anterior mid

79 as used to develop a classification model to discern each condition resulting in a sensitivity and sp

80 time the ability of metabolomic analyses to discern effects of this AEO on metabolite homeostasis at

81 pared with Verhoff von Giesen (VVG) stain to discern elastic tissue and Herovici stain to differentia

82 larity and demonstrate its effectiveness for discerning epigenetic differences.

83 DISCERN estimates the extent to which each gene is pertu

84 arkland Hospital, where I acquired skills in discerning evaluation and treatment of patients with com

85 Florida panther (Puma concolor coryi) and to discern factors influencing these patterns.

86 nservation during the twentieth century, and discerning fine-scale phylogeographic patterns is thus p

87 ransmission electron microscope, we directly discern five distinct stages of surface elemental rearra

88 The binding constant (Kd) discerned for the dye and HRP-II to Ni(2+) were 1.4 x 10

89 RS appears to be most discerning for patients with T3 MMR-I tumors, although m

90 g fictitious harmonics that are difficult to discern from pure nonlinear elastic effects.

91 les accommodates an excess proton is hard to discern from the broad vibrational spectra of dilute aci

92 n factors on the dogs' behaviour are hard to discern from their genetic heritage.

93 an cells where previously such could only be discerned from mouse models.

94 e degree to which different processes can be discerned from SAD patterns has not yet been rigorously

95 These clinical entities must obviously be discerned from the corresponding "pure" dermatitis, whic

96 rtex line, the presence of a monopole may be discerned from the experimental data alone.

97 changes in the spinal cord and brain can be discerned from trauma-induced consequences of SCI.

98 ng variation to help prioritize variants and discern functional consequence and hence the biological

99 The primary aim is to help discern functions in reward learning and decision-making

100 These findings discern fundamental molecular requirements for rationall

101 n in vivo systems have enormous potential to discern gene function in diverse physiological settings.

102 Discerning genetic contributions to diseases not only en

103 tional mutation-positive cases are needed to discern genotype-phenotype correlations associated with

104 at 91 (non-L(91)) had optimal sensitivity at discerning higher or lower HCC risk.

105 the neural mechanisms of attention, we must discern how attentional modulation varies by cell type a

106 (acrylic acid) (PAA-EG) (19.5 +/- 7.2 nm) to discern how coating charge affects nanoparticle uptake,

107 systems-type research approach will help to discern how environmentally induced mitochondrial dysfun

108 lso conducted under planktonic conditions to discern how interspecies competition contributes to E. c

109 the same pi-conjugated backbone material, we discern how the extent and speed of formation of the dop

110 ce engineered to lack nNOSmu and nNOSbeta to discern how the loss of nNOS impacts dystrophic skeletal

111 However, few studies have discerned how cells in biofilms respond to their environ

112 Discerning how aging impacts DC function to initiate ada

113 in trisomic mice exacerbates the problem of discerning how SAG acts to improve learning and memory.

114 w summarizes a fast-growing body of evidence discerning how the orexin/hypocretin system integrates i

115 zed constraining force has been difficult to discern, however, and a role for GC growth has not been

116 DISCERN identifies perturbed genes more accurately in sy

117 later age at onset may make it difficult to discern if aortic stenosis or other age-related comorbid

118 echanisms overlap, and it is now possible to discern important key trans-kingdom principles of NLR-de

119 eir biological function but are difficult to discern in bulk studies.

120 ng proteins (LMW PBP) have been difficult to discern in Gram-negative organisms.

121 n to the apoptotic response has been hard to discern in vivo.

122 ther distinct strains of Abeta prions can be discerned in AD patients, we performed transmission stud

123 requirements for effector translocation were discerned in bone marrow macrophages derived from C57BL/

124 rast, a strong indicator of zinc removal was discerned in comparing the relative abundance of core mi

125 two distinct strains of Abeta prions can be discerned in the brains of AD patients and that strain f

126 tive site, and a catalytic Mg(2+) ion can be discerned in the map obtained by cryo-EM.

127 The mechanisms of development discerned in this effort are guiding clinical research o

128 tions of these toxins have been difficult to discern, in part because the cytotoxicity profiles for t

129 xtraction kits, we confirmed that dPCR could discern individual copies of the redundant 23s rRNA gene

130 This resolution was essential for discerning individual fibrils, fibril paths, and their b

131 First, DISCERN infers conditional dependencies between candidat

132 sionality reduction techniques often help in discerning inherent structures.

133 ite quality was assessed using the validated DISCERN instrument.

134 a-syn-seeded aggregation, it is difficult to discern intracellular from extracellular exogenously app

135 requirement for SAP has made it difficult to discern its possible involvement in mature iNKT cell fun

136 le to mapping many features of chromatin and discerning its landscape in large genomes at unprecedent

137 re equipped with an evolvable probability to discern kin from non-kin.

138 n-mobility mass spectrometry approach, which discerns ligand binding to both soluble and membrane pro

139 from a visual scene, such as the capacity to discern local or global motion, direction of motion, sti

140 Discerning lymphatics from blood vessels using lineage-s

141 , the frequent sampling regime allowed us to discern meaningful fine-scale phase differences between

142 in compressed detection times for chemically discerning measurements that probe disease.

143 erscore the power of chemical proteomics for discerning mechanisms of drug action.

144 ope ratios in human hair as a new method for discerning MeHg exposure sources.

145 ility to be a highly sensitive, accurate and discerning method for single-cell studies including AS v

146 eview of current literature was performed to discern MGD in terms of pathophysiology, risk factors, a

147 To discern molecular pathways relevant to complex disease,

148 butions in excellent agreement with the CRM, discerns multiple quinolone species which differ slightl

149 ndom matrix theory-based network approach to discern network succession in groundwater microbial comm

150 Discerning network interactions among different species/

151 mal infrared imagery also available helps to discern nightglow structures and in some cases to attrib

152 poor diagnostic performance of median SWS in discerning no, equivocal, or definite urinary tract obst

153 ted potassium channel (BK) is well-suited to discern nuanced differences in regulation arising from c

154 Humans can discern object motion from identical retinal image displ

155 icant redundant signal such that rodents can discern odours using minimal stimulus-related informatio

156 share common clinical symptoms and cannot be discerned on standard clinical findings alone.

157 of a cancer and also have potential use for discerning ongoing mutational processes from historical

158 d from simple time-averaging are not able to discern pathology-related changes in autonomic control,

159 However, it has been difficult to discern patterns of dissemination owing to the limited n

160 tion and may represent an objective means to discern people with a need for treatment from those with

161 ited by "always-on" signals which compromise discerning phagocytosed particles from adherent particle

162 ated brain activation and are better able to discern phonemic content strongly support the concept of

163 tial distances, and can be used for visually discerning population structure as well as accurately in

164 ided important clues into carcinogenesis and discerned potentially druggable targets for metastatic c

165 comparative transcriptomics on this alga to discern processes relevant to quiescence in the context

166 is here shown to be an exciting approach to discern protein unfolding pathways for conformationally

167 antiviral properties that provide tools for discerning PVAN and AR as well as attractive targets for

168 environments provide novel opportunities to discern relationships between facial traits and behavior

169 a library of lysis-defective alleles of t to discern residues and domains important for holin functio

170 circuit-level mechanisms used by the mPFC to discern safety are not clear.

171 Website quality (DISCERN score) was poor in all site types but was worse

172 east cancer and lung cancer, genes with high DISCERN scores in each cancer are enriched for known tum

173 ified by gas chromatography, two groups were discerned: seasonally variable (n=17) and non-seasonal (

174 86 divergent eukaryotic genome sequences to discern sets of proteins that show similar phylogenetic

175 ficult as trait data is usually too noisy to discern shape, or trade-offs necessary for the theory ar

176 nd principal component analyses were used to discern shared immune response and genetic relationships

177 3,3'-o-BBV, 4,4'-o-BBV, and 4,7-o-PBBV also discerned similar L/M ratios.

178 n, we demonstrate the power of the method to discern similarities and differences between multiple ta

179 A post hoc analysis to discern sources of inter-individual variability confirme

180 The resultant inability of these models to discern species-specific features is a significant obsta

181 ative technique provides a unique ability to discern specific cell types based upon their metabolic s

182 We discerned specific changes in glutathione metabolites th

183 Moreover, the k-means analysis can further discern subtle differences among those closely located m

184 o begin breaking into language, infants must discern subtle statistical differences about people and

185 training radiologists learn to save lives by discerning subtle details of images that escape the noti

186 chnology affords limited resolving power for discerning subtle pathological changes associated with e

187 Discerning such trends makes predicting future choice va

188 ata mining approaches lies in the ability to discern synergetic effects between multiple parameters t

189 DISCERN takes two expression datasets as input: an expre

190 cal discrimination, but limit the ability to discern temporal detail.

191 The ability to discern temporally pertinent environmental events is ess

192 Decades of intensive study have yet to discern the actual mechanisms behind observed global pat

193 ibe mechanistic investigations attempting to discern the catalyst-ligand interactions occurring in th

194 is considered one of the primarily factor to discern the concentration of average plasma glucose over

195 evoked DA responses requires a framework to discern the contribution of DA release and reuptake.

196 cs data sources, which makes it difficult to discern the coordinated signal of interest from source-s

197 uish the different cultivars, and to clearly discern the different maturation stages, in each one of

198 We discern the direct incorporation of atmospheric carbon i

199 est that long-term trials may be required to discern the effects of T2D therapies on CHD risk.

200 tively long time horizon may be necessary to discern the efficacy of alternative intervention strateg

201 Here we discern the functional architecture of human NELF throug

202 f tACS effects on the motor system and helps discern the functional role of different oscillatory fre

203 ion of athletic performance has been used to discern the functions of these clocks in humans outside

204 rtook an untargeted metabolomics approach to discern the global metabolomics profile impacted by Merl

205 The goal of this work was to discern the impact of obesity, alone versus alongside ge

206 To fill major gaps in our ability to discern the influence of environmental changes on microb

207 need to evaluate the evidence objectively to discern the likelihood that any reported association mig

208 a cumulative time of approximately 1 mus to discern the mechanism of ion transport throughout TWIK-1

209 erstand its damage-tolerant behaviour and to discern the mechanisms of damage evolution under in-serv

210 as provided the tools and insights needed to discern the molecular and cellular processes regulating

211 me consuming methods with limited ability to discern the molecular mechanism and the minimum inhibito

212 However, to discern the molecular mechanisms responsible for this ac

213 To discern the molecular mechanisms underlying GR regulatio

214 Here, we attempt to discern the molecular organization and location of the N

215 ical improvements will be needed to reliably discern the most subtle diffusion abnormalities, especia

216 ically relevant in vitro system allows us to discern the multifaceted mechanism of FeCl3-induced thro

217 determined directly, making it difficult to discern the optimal strategy.

218 To discern the pathogen, we employed PCR coupled with elect

219 id mass spectroscopy, we are now starting to discern the patterns of these CYP-PUFA products in healt

220 ction of polarization vision, the ability to discern the polarization characteristics of light, is we

221 Future research will discern the precise role of (90)Y radioembolization in g

222 g water in time-series studies attempting to discern the presence of waterborne gastrointestinal illn

223 It is difficult to discern the proportion of blood lead (PbB) attributable

224 ystems revealed here may be explored to help discern the relationship of the various toxic activities

225 ographic changes were determined in order to discern the relative contribution of natural versus huma

226 iFORM/eQTL can particularly discern the role of cis-QTLs, trans-QTLs and their epist

227 erical simulations of the electric field, we discern the shape of the electrochemical double layer pr

228 polarization measurements that allowed us to discern the site-specific torsional relaxation at a low

229 nt for developing nonhuman primate models to discern the synaptic mechanisms of attention and learnin

230 The ability to discern the target of another person's gaze is critical

231 To discern the true causal variant(s), a variety of statist

232 h leads to a major advance in our ability to discern the underlying processes operating in ecological

233 e used next generation 454 pyrosequencing to discern the whole-body microbiome of the mosquito specie

234 In the present study we discerned the molecular mechanisms of potential interact

235 and progression has prompted an interest in discerning the associated regulatory mechanisms.

236 and (3) bleeding risk, which are pivotal for discerning the choice of antithrombotic therapy.

237 efficiency on a public metabolomics data set discerning the development of type 1 diabetes in a non-o

238 , its characterization might prove useful in discerning the essential traits for holin function.

239 Discerning the factors that control the reactivity of hi

240 Discerning the genetic contributions to complex human di

241 organisms present a unique model system for discerning the individual contributions of the alpha and

242 Finally, discerning the mechanisms underlying NMDAR dysregulation

243 Discerning the minimal set of human-specific factors req

244 ring new microbial systems and capabilities, discerning the molecular mechanisms that mediate microbi

245 Discerning the molecular mechanisms that regulate E-cadh

246 or dimeric proteins but have limitations in discerning the order of larger oligomers.

247 Discerning the proteins and biochemical pathways targete

248 cohort of healthy adult men aimed at further discerning the specific roles of androgen and estrogen d

249 Initial studies focused on discerning the structural and electronic features of the

250 nd establish an important first step towards discerning the underlying transport properties of perovs

251 go1 null and slicer-deficient mutants can be discerned, the results of both transcript profiling appr

252 erential expression of the TSLP isoforms and discern their biological implications under homeostatic

253 d, and demonstrate how optogenetic tools can discern their functional architecture.

254 hirikof Island relative to extant breeds and discern their origins.

255 l displacement, of individual clusters to be discerned, thereby demonstrating a robust covalent attac

256 We present novel robust analysis tools to discern these two phases in tracks.

257 Discerning these effects is critical to a better underst

258 Here, we present a novel model system to discern this paradoxical role of TGFss1 using the MDA-MB

259 s during stress events, and the challenge is discerning those interactions that most influence diseas

260 Being able to discern three sources with two isotopes will be of great

261 entified rare subtypes that are difficult to discern through clinical observations, providing impetus

262 ing of viral processes that are difficult to discern through strictly experimental approaches.

263 d and persistence of RSV and how this may be discerned through an improved understanding of the intro

264 ound: music training improves our ability to discern tones; experience with food and wines can refine

265 also revealed liabilities that allowed us to discern two properties of an ideal RAF inhibitor: high-b

266 Taken together, these results discern two subtypes of CAF that promote OSCC cell invas

267 ls of these FtsZ structures are difficult to discern under conventional fluorescence microscopy, sing

268 exposed to chronic alcohol treatment and to discern underlying mechanisms.

269 Second, DISCERN uses a new likelihood-based scoring function to

270 f population structure that are difficult to discern using existing methods for summarizing genetic v

271 dent of one another, making patterns hard to discern using standard univariate analyses.

272 genetic relationships of R. multicaudata are discerned using a phylogenetic approach with the nuclear

273 e and administration of bevacizumab could be discerned using the PCA.

274 To discern virulent from innocuous microbes, the innate imm

275 For example, to discern what is and what is not impacted by stimulation,

276 related to biological processes are hard to discern when comparing various datasets.

277 ransgenic littermate control (NLC) mice were discerned when stimulated with supramaximal concentratio

278 Here, we attempt to discern where the idea is useful to apply and where it i

279 rstood, in part because of the difficulty in discerning where CaMKII binds in live cells.

280 mate change studies from single sites cannot discern whether an observed response is site-dependent o

281 The aim of our study was to discern whether breast milk of ITP mothers contained ant

282 Here we present a Q-method to discern whether changed pathway response is caused by me

283 these environmental factors makes it hard to discern whether ecological competition exerts an upper l

284 netic pathway to restore FMR1 expression and discern whether levels of 5hmC correlate with phenotypic

285 re, these studies are only the first step to discern whether natural selection is responsible and cap

286 To discern whether targetable neoantigens exist in PDAC, we

287 However, it is important to discern whether the increases in CA-US HIV-1 RNA are due

288 However, it has not been yet discerned whether a tight U-turn or an alternative confo

289 unction over chemical form, in an attempt to discern which among the many molecular features are most

290 on to individual splicing factors or even to discern which are critical for catalyzing the splicing r

291 ell antigen identification approaches do not discern which epitopes drive protective immunity during

292 chanisms have been characterized in order to discern which of them are favoured under conditions simi

293 ing they will, and that campaign callers can discern which self-predicted voters will not actually vo

294 of lateral root priming that may be used to discern which type of mechanism is most likely to drive

295 s and microscopic mechanism are difficult to discern with current experiments.

296 pus evoked spiking activity that was readily discerned with bath-applied RVF5, demonstrating the util

297 o other components and can be, in principle, discerned with improved sensitivity in the phase-resolve

298 ine responses is resolved by ET-MIp and best discerned within a short evolutionary distance.

299 Two cohorts could be discerned within the CVID group: group 1 with an abnorma

300 Temporal cues are important for discerning word boundaries and syllable segments in spee