ライフサイエンスコーパス: disclose

1 ts and participants choose the phenotypes to disclose.

2 strated" Lewis acid/Bronsted base complex is disclosed.

3 ch the carboxylate moiety acts as a relay is disclosed.

4 A Ni-catalyzed method for arylboration is disclosed.

5 vailable epoxides and allyl electrophiles is disclosed.

6 liphatic-substituted allylic electrophile is disclosed.

7 unds in alkyne annulation reactions are also disclosed.

8 1 degrees amine thiourea catalyst system is disclosed.

9 oach to 3-pyrrolin-2-one fused carbazoles is disclosed.

10 ange of carbonyl compounds and aldimines are disclosed.

11 n allylic linker under neutral conditions is disclosed.

12 ute to the C1-C15 subunit of sorangicin A is disclosed.

13 d, formal homo-Nazarov cyclization have been disclosed.

14 lation regarding speech sounds have not been disclosed.

15 re C-3-substituted tetrahydroisoquinoline is disclosed.

16 c substitution with silicon electrophiles is disclosed.

17 ioselective arylboration of alkenylarenes is disclosed.

18 e with an attached bulky silyl group is also disclosed.

19 cyclic sulfoximine into a pyrroline, is also disclosed.

20 reactions of propargyl aryldiazoacetates are disclosed.

21 ligands, solvent, and catalyst structure are disclosed.

22 pha-fluoro carbonyl compounds have yet to be disclosed.

23 ment of an enantioselective variant are also disclosed.

24 1,3-bidentate donor ligand hemilability, are disclosed.

25 lpha,beta-unsaturated esters selectively are disclosed.

26 via three conceptually orthogonal routes are disclosed.

27 m optimization and its application scope are disclosed.

28 ts on a carbo-benzenoid fragment are finally disclosed.

29 d chiral dinitrogen ligands that we recently disclosed.

30 kyl-containing 3-azabicyclo[3.1.0]hexanes is disclosed.

31 ustrated Lewis acid/Bronsted base complex is disclosed.

32 y mechanistic details of the method are also disclosed.

33 generate Z- or E-trisubstituted alkenes are disclosed.

34 ilanes and siloxy- or alkoxyhydrosilanes are disclosed.

35 C-H functionalization of C-alkenyl azoles is disclosed.

36 ructural and functional parameters have been disclosed.

37 onalized through docking into the previously disclosed 3-CRBN-GSPT1 cocrystal ternary complex.

38 We have recently disclosed 5-phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5

39 1 x 10(-4) and a look-up evaluation of these disclosed 8 SNPs in 4 loci, with an interaction P < 0.05

40 Here, we disclose a class of phosphines that enable the Ni-cataly

41 In the process, we disclose a detailed DFT study of equilibrium geometries

42 We disclose a detailed examination of a thermally induced s

43 Herein we disclose a detailed study examining the structure of 18

44 Herein, we disclose a facile way to realize designed micropatternin

45 Here, we disclose a general and reliable reaction manifold for th

46 Herein, we disclose a general strategy for aliphatic gamma-C(sp(3)

47 Herein, we disclose a general strategy for precise tuning of loop d

48 onfirm the respective gelation processes and disclose a higher critical gelation concentration for th

49 In this work, we disclose a metal-ion-mediated strategy to assemble trime

50 Here we disclose a modular synthesis of pleuromutilins by the co

51 Our findings disclose a molecular mechanism based on PARP1-Erk synerg

52 for substrate activation; in addition, they disclose a new inhibitor-binding mode and a distinct sma

53 These findings disclose a new mechanism of TH regulation by phosphoryla

54 These results disclose a new role for FasL in modulating immunosuppres

55 Our results disclose a novel interplay between ubiquitin- and phosph

56 Herein we disclose a novel method for the facile transfer of prima

57 Herein, we disclose a semisynthetic, catalytic approach for structu

58 Here we disclose a simple route to nanoscopic 2D woven structure

59 We disclose a strategy for Ni-catalyzed dicarbofunctionaliz

60 Herein we disclose a systematic study of a single CH HB by using t

61 Herein, we disclose a template-assisted method for the regioselecti

62 In this report, we disclose a very efficient catalytic protocol for site-sp

63 l magnetic resonance imaging and angiography disclosed a decrease in blood flow, an indirect sign of

64 trificans and Cupriavidus metallidurans BPHs disclosed a homo-oligomeric double-ring architecture in

65 mpetitive binding of Na(+) These experiments disclosed a marked decrease in the affinity of Na(+) to

66 The final pathology report disclosed a moderately differentiated invasive ductal ca

67 ng anti-parallel MTs in the phragmoplast and disclosed a novel action of MAP65-4 at the cortical cell

68 of patients diagnosed with macular dystrophy disclosed a novel mutation in the GUCA1A gene, namely a

69 We disclosed a principle controlling Sirt1 activity and unc

70 ing and confocal fluorescence microscopy, we disclosed a robust increase in the expression of gephyri

71 We have recently disclosed a series of orally active tetrahydroisoquinoli

72 atic analysis of 1971 breast cancer patients disclosed a significant correlation between the expressi

73 Notably, gene set enrichment analysis disclosed a significant correlation between ZAK+ colorec

74 e of the phosphatase domain of PTPN12, which disclosed a specific PTPN12-insert-loop harboring a cycl

75 xploration: Recently, Linclau and co-workers disclosed a straightforward (19)F-NMR method for determi

76 escence microscopy of wild-type mouse retina disclosed a strong DNM1L expression in the ganglion cell

77 racentesis improved abdominal discomfort and disclosed a transudate, suggestive of portal hypertensio

78 Kinetics studies of m4-1BB disclosed a very tight nanomolar binding affinity to m4-

79 This work discloses a powerful and potentially widely applicable a

80 This report discloses a prevalent SPINK5 founder mutation in Finland

81 embrane proteins in type 2 diabetes mellitus discloses a similarity between the diabetic macroangiopa

82 formation products of geogenic compounds and disclosed additives have not been described.

83 mation products and underscores the value of disclosing additives injected into the subsurface.

84 recommended for quality control of wine and disclosing adulterated samples.

85 is essential to understand how surgeons are disclosing adverse events, factors that are associated w

86 practice, and recognising, responding to and disclosing adverse events, including errors and near mis

87 The component-resolved diagnostics disclosed also a high heterogeneity at molecular level.

88 Our study discloses amyloidogenic LC production as an intrinsic PC

89 Here we disclose an efficacious hybrid molecule 4-(5-Amino-1,2,3

90 Here, we disclose an integrated microfluidic emulsion creamer tha

91 rried out by the same RTK monomer in cis and disclose an obligatory role for receptor dimerization in

92 Herein, we disclose an unprecedented in vivo reduction process that

93 rarchical early visual processing, the model disclosed and quantified the neural temporal dynamics ac

94 of catalytic reactions has been successfully disclosed, and catalysis has been examined for each meta

95 as candidate serine hydrolase inhibitors are disclosed, and represent the synthesis and study of a pr

96 practical use, and then discusses the newly disclosed applications in sensing, bioimaging, novel sol

97 homogeneous experimental data, which is also disclosed as Supporting Information .

98 The disclosed Au(I)-catalyzed reaction utilizes 2-propargylo

99 I) analysis of viral proteins can eventually disclose biological mechanisms and thus provide new insi

100 CHD risk was disclosed by a genetic counselor and then discussed with

101 Risk was disclosed by a genetic counselor followed by shared deci

102 Their structure was ultimately disclosed by an indirect Fourier transform of static lig

103 cal PD-1/PD-L1 inhibitors have been recently disclosed by Bristol-Myers Squibb.

104 nthesis of intricate fused N-heterocycles is disclosed by employing C-H activation and ring-rearrange

105 f the enantioselectivities of this reaction, disclosed by List et al. using a cinchona alkaloid-deriv

106 The observed differences were fully disclosed by mechanistic studies involving fluorescence

107 ling connectivity abnormalities that are not disclosed by other modalities.

108 On the basis of previous methods disclosed by our lab, we sought to develop a predictive

109 The insights disclosed by our simple model contribute a more intimate

110 Our study discloses CaM7 as a PEN3-interacting protein crucial to

111 Here, we disclose chemical processes that result in formation of

112 ce appropriate education is delivered to the disclosing clinicians.

113 We disclose compartmentalized corelease of glutamate and GA

114 stematic chemical improvements on publically disclosed compounds.

115 orts assessed adequacy of blinding, 18 (53%) disclosed conflicts of interest, and 19 (56%) received f

116 y Cochrane reviews and reviews whose authors disclosed conflicts of interest.

117 as long as the number of missing links (non-disclosed contacts) is not very large.

118 We now disclose crystal structures of the HK:RR complex DesK:De

119 ite located between the VSD and the TRP box, disclosing differences in the binding modes for the agon

120 PR-OCTA disclosed dilated vessels in the intermediate and deep p

121 Copy number alteration analysis disclosed distinguishable amplifications in the 3q chrom

122 but only a very few nurses actually reported disclosing errors in practice.

123 nurses' attitudes and experiences concerning disclosing errors to patients and perceived barriers to

124 The sugar industry did not disclose evidence of harm from animal studies that would

125 Imaging studies disclosed extraocular muscle swelling (8 cases), most fr

126 The aim of the present work is to disclose factors governing conformational behavior of FC

127 Despite ethical and legal obligations to disclose findings promptly, most HLACTs did not report r

128 tors that are potent and selective have been disclosed for ATAD2, CBP, BRD7/9, BRPF, BRPF/TRIM24, CEC

129 tical chiral ruthenium-NHC-diamine system is disclosed for the enantioselective hydrogenation of isoc

130 alladium-catalyzed reductive azo cleavage is disclosed for the synthesis of diverse heteroaromatic 1,

131 Rather, the disclosed formulations are based on a non-hygroscopic di

132 At a minimum, 60% of the 24 reviews did not disclose full search details or apply appropriate statis

133 d support the use of complementary assays to disclose genetic abnormalities not revealed by current N

134 analyze complex traits but their ability to disclose genetic architectures is often limited by stati

135 The advantages and disadvantages of disclosing genetic predisposition to high BP for risk st

136 We hypothesized that disclosing genetic risk for CHD to individuals influence

137 Whether disclosing genetic risk for coronary heart disease (CHD)

138 We disclose herein the development of functional and high-v

139 Disclosed herein is an efficient synthetic route for the

140 Disclosed herein is that vinyl ethers serve as protectin

141 The results disclosed herein should create opportunities across a va

142 nic acids, and N-fluorobenzenesulfonimide is disclosed herein.

143 hensive screen of the expression of the gene discloses high transcript levels in several tumor tissue

144 ceased organ donors from 2003 to 2015 with a disclosed history of increased risk behavior (IRB) inclu

145 These data result in a tangible model disclosing how hPSC-released factors deflect CHIR99021-i

146 e of bis(2-ethylhexyl) phthalate, which is a disclosed HVHF additive, that was notably absent in a re

147 We disclose in this paper a ligand-based drug design approa

148 vant adverse effects or pregnancy risks were disclosed in a minority (10 of 31 [32%] and 6 of 14 [43%

149 proportion of face-selective responses were disclosed in the right ventral anterior temporal lobe, a

150 The approach disclosed in this work therefore constitutes a powerful

151 In eyes with DR, 3-layer PR-OCTA disclosed incongruent areas of nonperfusion and varied v

152 rs receiving payments, 22 did not accurately disclose industry relationships.

153 they do about other health matters, and may disclose information to third parties when necessary.

154 Only 16 (26%) disclosed information about clinician licensure, and som

155 sis, (2) creating a personal connection, (3) disclosing information regarding the acute problem in th

156 Disclosed is a mild, scalable, and chemoselective cataly

157 Disclosed is a mild, scalable, visible-light-promoted cr

158 FFFS scorers compared to higher FFFS scorers disclosed larger N1/P2 amplitudes to the highest tone in

159 EDI-OCT disclosed macular subretinal fluid with an increase of c

160 egislation requiring radiology facilities to disclose mammographic breast density information to wome

161 Our results show that beacons can disclose membership and implied phenotypic information a

162 inks can be used to encrypt and selectively disclose multicolor patterns for anticounterfeiting appl

163 reaction employing 2-hydroxyacetophenones is disclosed, namely Michael-hemiacetalization reaction of

164 ve to the currently used screening assays to disclose new anti-RT drugs and identify at the same time

165 knowledge on the enzyme diversity world and discloses new families for which a clear classification

166 oped zinc oxide via a two-colour laser field discloses new material functionalities.

167 Every week, articles disclosing new antifungal leads reported as promising st

168 e role of hydrogen bonds in liquid dynamics, disclosing new research opportunities and unexplored int

169 ctivity relationship studies of a previously disclosed nonacidic sulfonamide FFA4 agonist.

170 Full details of studies are disclosed on the total syntheses of binding pocket analo

171 ng or counseling patients about firearms and disclosing patient information about firearms to others,

172 sts from parents or family caregivers not to disclose poor prognosis to seriously ill children can be

173 All eyes except for the eyes in Case 4 disclosed positive VEGF staining.

174 y of structure-activity relationships (SARs) disclosed properties with respect to ring size, sulfur p

175 Additionally, our studies disclosed regions of the NiV G and F glycoproteins dispe

176 omy with pelvic lymph node dissection, which disclosed residual high-grade muscle-invasive urothelial

177 Site-directed mutagenesis disclosed residues Phe(241) and Ser(203) in MFAP4 as bei

178 scovered, and tumor and bone marrow biopsies disclosed rhabdomyosarcoma.

179 e of the characterization of full genomes to disclose RHDV evolution and show that lagoviruses' diver

180 Electrophysiological data disclose rich dynamics in patterns of neural activity ev

181 se of genetic testing raises questions about disclosing secondary findings, including pleiotropic inf

182 We herein disclose selective nascent polymer catch and release (SN

183 The meta-analysis of these studies disclosed significant effects for music on pain after su

184 ethylated DNA immunoprecipitation sequencing disclosed significantly less 5-hmC binding in the 3' unt

185 ultivariate analysis of the primary endpoint disclosed soft pancreatic texture (odds ratio: 2.1, P =

186 Our experiments disclosed strictly reciprocal and conspicuously focal in

187 2D Dirac plasmons in 3D nanoporous graphene disclosing strong plasmonic absorptions tunable from ter

188 cteristics, in particular, in the context of disclosing structure-property correlations.

189 VU590 was the first publicly disclosed, submicromolar-affinity (IC50 = 0.2 muM), smal

190 on about adverse events and experiences with disclosing such events were completed by 35 of these 67

191 e core of ineleganolide, which was the first disclosed synthesis of the core of the norditerpene natu

192 Previously disclosed TAFIa inhibitors having a urea zinc-binding mo

193 to develop privacy-preserving approaches to disclose TDT statistics with a guarantee that the risk o

194 e underwent left inguinal orchiectomy, which disclosed testicular carcinoma composed of 90% choriocar

195 Herein, we disclose that compounds having the O-glycosidic bond rep

196 Thus, our results disclose that in addition to OPA1, OPA3, MFN2, AFG3L2 an

197 These results disclose that rTMS induces coordinated Ca(2+)-dependent

198 Herein, we disclose that such Au(III) complexes can undergo facile

199 We here disclose that the corelease of glutamate and GABA, as we

200 e well between August 2010 and October 2011, disclose that the sinking of spill-associated substances

201 AKAP350A with centrosomes, and these studies disclosed that AKAP350A spans the bridge between centrio

202 It was disclosed that changing the reaction conditions and isol

203 several inhibitors of RIP2 kinase have been disclosed that have contributed to the fundamental under

204 tecture in mouse intestinal epithelial cells disclosed that microbiota colonization leads to activati

205 This disclosed that movement alters limb proportions and regu

206 Additional mutational experiments disclosed that neither truncation of the MaLPMO10B famil

207 tivation or inhibition in AFD (or intestine) disclosed that PKC-2 regulates initiation and duration o

208 We also disclosed that protein overload first acts on the expres

209 Quantitative analysis disclosed that stages 3-4 and 5 carry significant impair

210 Binary logistic regression analysis disclosed that status epilepticus, psychosis and cogniti

211 brain data-driven graph theoretical analysis disclosed that striatal regions constitute a cohesive mo

212 Binding studies disclosed that the competitive inhibitor isoeugenol is p

213 nged miRNAs and principle component analysis disclosed that the most prominent change in miRNAs expre

214 anti-peroxisome membrane protein antibodies disclosed that the msn2Deltamsn4Delta strain had fewer p

215 metry, and siRNA-mediated gene knocking down disclosed that the mutation disrupts binding of a splici

216 This synthetic study disclosed that the reported structure of baulamycin A ne

217 It was only disclosed that the staff was a confederate during the de

218 th and without subcutaneous 260.8 hybridomas disclosed that this IgA did not affect B. thetaiotaomicr

219 This study discloses that benzene-1,4-diboronic acid (BDBA) was eff

220 The comparison of Ragone plots further discloses that NVPF-NTP presents the best power performa

221 Additionally, we disclose the co-crystal structure of our inhibitor serie

222 We disclose the conformational transition of Cas9 from its

223 Herein, we disclose the construction of aromatic nitriles via direc

224 Here, we disclose the design and validation of a high-throughput

225 Here, we disclose the discovery of a very potent and selective no

226 ole-brain computational modeling was used to disclose the effects of DBS during resting-state functio

227 In addition, we disclose the efficacy of 4a in a mouse EAE model, which

228 We also disclose the first crystal structure of MTHFD2 in comple

229 Herein, we disclose the first examples of the sigma-bond metathesis

230 Herein, we disclose the first light-controlled, cobalt-catalyzed [2

231 Herein, we disclose the first total syntheses of three members, sca

232 Here we disclose the first total synthesis and structural confir

233 Herein, we disclose the first total synthesis of this highly strain

234 Herein, we disclose the first X-ray crystal structures of inhibitor

235 generated ADMET rules, avoiding the need to disclose the full chemical structures.

236 tical model of mouse ventricular myocytes to disclose the key mechanisms underlying the continual tra

237 k individual results, how researchers should disclose the legal risks to participants during the info

238 could use in the informed consent process to disclose the legal risks.

239 f treated keratinocytes and naive T cells to disclose the molecular details that regulate the activat

240 ants could be required in some situations to disclose the presence of certain chemicals when selling

241 Furthermore, we disclose the proinflammatory potential of NKG2C(bright)

242 o want to see their results, but they should disclose the risks of obtaining the information as part

243 We disclose the role of miR-708-KPNA4-TNF axes in PCa metas

244 Kinetic studies are a suitable tool to disclose the role of tiny reagent fractions.

245 (MCI) not converting or converting to AD-to disclose the spatial distribution of the independent com

246 Herein, we disclose the syntheses and reactivity of three Ntau-imid

247 for the patient's welfare (57 of 60 [95%]), disclosed the adverse event within 24 hours (58 of 60 [9

248 Pain ratings disclosed the anticipated analgesic interaction between

249 For the first time, we have disclosed the base-mediated conversion of (Z)-styryl pyr

250 We previously disclosed the discovery of rationally designed N-((1-(4-

251 Recently, we disclosed the first highly Z-selective isomerization of

252 Herein is disclosed the first small molecule allowing their select

253 We previously disclosed the identification of cereblon modulator 3 (CC

254 tigations of Yersinia-flea interactions have disclosed the important steps in the evolution and emerg

255 The isotope ratios disclosed the majority of the females to be nonlocal, wh

256 NMR and molecular modeling studies disclosed the molecular bases for the binding of 19 to C

257 GlaxoSmithKline has recently disclosed the results of a phenotypic screening of an in

258 Previously, we disclosed the role of Cav1.2 alpha1 in mouse and human T

259 lyses of the P. luminescens lectin PllA have disclosed the structural basis for PllA's high specifici

260 Mutational studies disclosed the tyrosine 373 close to the surface to form

261 This paper discloses the design, synthesis, and imaging application

262 complexes with bi- and multidentate ligands discloses the distortion pathway associated with each pa

263 This work discloses the first general solution for converting olig

264 Quantitative computational modeling discloses the nature of foreign body responses.

265 This study discloses the synthesis of such agents and an analysis o

266 and the string is verified or denied without disclosing the actual signature.

267 urely authenticate and validate GMOs without disclosing the actual signature.

268 metabolome studies have been instrumental in disclosing the contributions of major pathways for centr

269 IQGAP1 affinity for CDC42 and RAC1, clearly disclosing the critical role of RGCT for these interacti

270 ide polymorphism array analysis, we aimed at disclosing the pathways that are molecularly deregulated

271 T is often low, and partners commonly do not disclose their HIV status to each other.

272 -HSD14 nonsteroidal inhibitors as well as to disclose their structure-activity relationship.

273 rchers to find new uses for old drugs and to disclose their therapeutic profiles or side effects.

274 on to have the specialty treatment when they disclosed their bias or discussed the opportunity for th

275 In addition, VL+ YMSM who disclosed their HIV status to sex partners were more lik

276 Only 34.8% disclosed their use of meditation with a health provider

277 hird, equipoise was undermined by clinicians disclosing their personal opinions or predictions about

278 ure of their specialty, yet not all surgeons disclose these events to patients.

279 ble industry payments and did not completely disclose these payments.

280 lution must decide whether, when, and how to disclose to study participants their individual results.

281 Moreover, the GM2-MPLA conjugate was disclosed to elicit strong immune responses without the

282 Sleep study information disclosed to sleep physicians comprised level 1 (L1) PSG

283 The expert panel vote was disclosed to the patient by the patient's surgeon before

284 any nurses reported that most errors are not disclosed to the patient.

285 graph filtration on alpha-gamma correlation disclosed topological invariants to explain memory gatin

286 All of these results successfully disclose two new promising two-dimensional half-metallic

287 impact of hiding holds whether opting not to disclose unflattering (drug use, poor grades, and sexual

288 tances (hydrocarbons and hopane biomarkers), disclosed UNGD additives (e.g., hydrocarbons, phthalates

289 Optimization efforts based on previously disclosed unsubstituted 6,7-dihydro-4H-triazolo[4,5-c]py

290 ls to give beta-aryloxycarbonyl compounds is disclosed using a chiral pyridine oxazoline-ligated pall

291 rotected phenethylamines and benzylamines is disclosed using a combination of norbornene and pyridine

292 ls to construct propargylic stereocenters is disclosed using a new pyridine oxazoline ligand.

293 ore, during, and after treatment with BEP to disclose valid pulmonary toxicity risk factors.

294 lecular dynamics investigations on ubiquitin disclose variable interactions with concentrated solutes

295 Here we disclose VH298, a potent VHL inhibitor that stabilizes H

296 as demonstrated by portal angiography, which disclosed virtually complete portosystemic shunting in F

297 tal diseases among the general public and to disclose whether these gaps are culturally consistent.

298 A catalytic activation strategy is also disclosed, which may have broad implications for use in

299 nt of Fischer azaindolization methodology is disclosed, which provides a synthetic entryway into fuse

300 CTCs were disclosed with CellSearch System, DTC with immunocytolog