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1 mplex life cycle of the amoeba Dictyostelium discoideum.
2 ologs (ChdA, ChdB and ChdC) in Dictyostelium discoideum.
3 database for the social amoeba Dictyostelium discoideum.
4 approach in the model organism Dictyostelium discoideum.
5 ocial stage of an amoeba host, Dictyostelium discoideum.
6 s including most metazoans and Dictyostelium discoideum.
7 as a role in cell migration in Dictyostelium discoideum.
8 smoregulation as well as cell motility of D. discoideum.
9 tween humans and the protozoan Dictyostelium discoideum.
10 es involved in resistance to predation by D. discoideum.
11 arly decreased resistance to predation by D. discoideum.
12 chemotaxis and cytokinesis in Dictyostelium discoideum.
13 ation by the phagocytic amoeba Dictyostelium discoideum.
14 ays of chemorepellent gradient sensing in D. discoideum.
15 in the developmental cycle of Dictyostelium discoideum.
16 ved between the yeast Pichia pastoris and D. discoideum.
17 pe locus of the model organism Dictyostelium discoideum.
18 ms, Caenorhabditis elegans and Dictyostelium discoideum.
19 ought after folic acid receptor, fAR1, in D. discoideum.
20 he model organism database for Dictyostelium discoideum.
21 for the extraction of RNA from Dictyostelium discoideum.
22 esion during cell migration in Dictyostelium discoideum.
23 and for obtaining nutrients in Dictyostelium discoideum.
24 or tyrosine kinase-like protein, VSK3, in D. discoideum.
25 at are affected by cisplatin treatment of D. discoideum.
26 rom cells of the social amoeba Dictyostelium discoideum.
27 hemotaxis and cell adhesion in Dictyostelium discoideum.
28 ration of the amoeboid form of Dictyostelium discoideum.
29 ve of Pro-143 in the amebazoan Dictyostelium discoideum.
30 specific function of volatile terpenes in D. discoideum.
31 of chimaerism experienced by the related D. discoideum.
32 ecies and from the slime mold, Dictyostelium discoideum.
33 in apicomplexan parasites and Dictyostelium discoideum.
34 reduced drug accumulation in transformed D. discoideum.
35 e systems in the social amoeba Dictyostelium discoideum.
36 se (MOD) for the social amoeba Dictyostelium discoideum.
37 nd spores of the social amoeba Dictyostelium discoideum.
38 theta, DGKA, was identified in Dictyostelium discoideum.
39 tant forms of PfCRT to acidic vesicles in D. discoideum.
40 nto cAMP, the primary chemoattractant for D. discoideum.
41 cell fusion during macrocyst formation in D. discoideum.
42 visualize polyP extracted from Dictyostelium discoideum.
43 cheating in the social amoeba Dictyostelium discoideum.
44 hemotaxing unicellular amoeba, Dictyostelium discoideum.
45 y studied in the social amoeba Dictyostelium discoideum.
46 of the yeast prion protein Sup35 (NM), in D. discoideum.
47 presented by the social amoeba Dictyostelium discoideum.
48 robe (protist), the slime mold Dictyostelium discoideum.
49 heterochromatin of the six chromosomes in D. discoideum.
50 on single cells of the amoeba Dictyostelium discoideum.
51 on-muscle myosin II motor from Dictyostelium discoideum.
57 bprocess of chemorepulsion, in Dictyostelium discoideum-a well characterized model eukaryotic system.
60 molecules that mediate allorecognition in D. discoideum also control the integration of individual ce
62 ny eukaryotic cells, including Dictyostelium discoideum amoebae, fibroblasts, and neutrophils, are ab
63 ss severe during growth within Dictyostelium discoideum amoebae, indicating that the requirement for
64 ound on the plasma membrane of Dictyostelium discoideum amoebae, was postulated previously to play a
68 binding protein (ACBP; AcbA in Dictyostelium discoideum), an unconventionally secreted protein, is de
69 oximately 1-2 mM IC(50) versus Dictyostelium discoideum and a human cell line, indicating selective a
70 most abundant retroelement in Dictyostelium discoideum and constitutes the pericentromeric heterochr
71 ated migration of the amoeboid Dictyostelium discoideum and for the lamellipod-driven migration of hu
72 lism genes confer cisplatin resistance in D. discoideum and in human cells, raised interest in the re
74 haracterized chemotactic cells Dictyostelium discoideum and neutrophils, signaling to the cytoskeleto
77 l multicellular development in Dictyostelium discoideum and reconstruct how some of these mechanisms
80 residues follows myosin II in Dictyostelium discoideum) and the water molecule that spans this salt
81 unction within macrophages and Dictyostelium discoideum, and for intrapulmonary proliferation in mice
82 gans, Acathamoeba castellanii, Dictyostelium discoideum, and Galleria mellonella have provided means
83 he genome of the social amoeba Dictyostelium discoideum, and show, with the use of heterologous expre
84 ed Acanthamoeba castellanii or Dictyostelium discoideum, and the intracellular growth defect was comp
90 a, Vermamoeba vermiformis and Dictyostellium discoideum) are permissive to M. bovis infection and tha
91 ds, including the well-studied Dictyostelium discoideum, are amoebae whose life cycle includes both a
92 charomyces pombe and DnmA from Dictyostelium discoideum, are strongly stimulated by prior queuosine (
93 ell as the results of decades of study of D. discoideum as a model for development, allow us to explo
95 Despite widespread interest in Dictyostelium discoideum as a model system, almost no molecular data e
96 -editing occurs at all predicted sites in D. discoideum as evidenced by changes in the sequences of i
98 tion limits the potential for cheating in D. discoideum because defecting on prestalk cell production
100 ignal transduction pathways in Dictyostelium discoideum but Galpha subunit-effector interactions have
101 homologues, PkbA and PkbR1, in Dictyostelium discoideum by phosphorylation of activation loops (ALs)
102 sms: Saccharomyces cerevisiae, Dictyostelium discoideum, Caenorhabditis elegans, Drosophila melanogas
103 ted sequence identity with the Dictyostelium discoideum cAMP receptor cAR1 and the Aspergillus nidula
104 ng cells of the social amoebae Dictyostelium discoideum can aggregate and develop into multicellular
105 stance phenotype conferred on transformed D. discoideum can be reversed by the channel-blocking agent
107 er clones of the social amoeba Dictyostelium discoideum carry bacteria to seed out new food populatio
109 , which is produced by growing Dictyostelium discoideum cells and inhibits their proliferation, also
110 transport are investigated in Dictyostelium discoideum cells by single particle tracking of fluoresc
111 Upon starvation, individual Dictyostelium discoideum cells enter a developmental program that lead
112 ectional biases in chemotactic Dictyostelium discoideum cells in a flow chamber with alternating chem
115 of this response, we subjected Dictyostelium discoideum cells to measurable temporal and spatial chem
116 th classes of RNR genes were expressed in D. discoideum cells, although the class I transcripts were
117 l cyclase (ACA) at the back of Dictyostelium discoideum cells, an essential determinant of their abil
118 en imaging rapid morphological changes in D. discoideum cells, as well as improved contrast and resol
119 of cytokinesis, in rounded-up Dictyostelium discoideum cells, the small G-protein Rap1 is activated
123 ies of the diiron-oxo/radical cofactor of D. discoideum class I RNR are similar to those of the mamma
126 holderia inhibit the growth of non-farmer D. discoideum clones that could exploit the farmers' crops.
130 65) of the myosin-2 motor from Dictyostelium discoideum (Dd) is proposed to be a key residue in an al
131 The fluorescence properties of Dictyostelium discoideum (Dd) myosin II constructs containing a single
134 gelation factor (ABP-120) from Dictyostelium discoideum (ddFLN5) by NMR spectroscopy to provide a bas
135 ly regulated Na-H exchanger in Dictyostelium discoideum (DdNHE1) localizes to the leading edge of pol
136 re, we demonstrate that peroxidase A from D. discoideum (DdPoxA) is a stable, monomeric, glycosylated
137 that class I is the principal RNR during D. discoideum development and growth and is important for s
138 face cAMP receptors throughout Dictyostelium discoideum development, controlling chemotaxis and morph
140 s, including the social amoeba Dictyostelium discoideum, development is often marked by dynamic morph
142 zymes, such as PDE for cAMP in Dictyostelium discoideum (Dicty) and BAR1 for mating factor alpha in S
143 We have engineered a mutant of Dictyostelium discoideum (Dicty) myosin II that contains the same fast
148 liana, Caenorhabditis elegans, Dictyostelium discoideum, Drosophila melanogaster, Saccharomyces cerev
149 turally occurring genotypes of Dictyostelium discoideum during the formation of chimeric fruiting bod
150 ectly observe the structure of Dictyostelium discoideum dynein dimers on microtubules at near-physiol
152 s, including the social amoeba Dictyostelium discoideum, encode both a class I and a class II RNR.
154 ed vesicles from mutant-PfCRT-transformed D. discoideum exhibit features of the CQR phenotype, consis
157 e results change our understanding of the D. discoideum farming symbiosis by establishing that the ba
160 shown that a little-studied component of D. discoideum fitness--the loner cells that do not particip
161 Schizosaccharomyces pombe and Dictyostelium discoideum for methylation of the Geobacter tRNA-Asp and
163 We show that the non-metazoan Dictyostelium discoideum forms a polarized epithelium that is essentia
168 FPPS from Leishmania major, in Dictyostelium discoideum growth inhibition, in gammadelta T cell activ
170 we show that the social amoeba Dictyostelium discoideum has a primitive farming symbiosis that includ
171 e show that the model organism Dictyostelium discoideum has evolved to normally encode long polygluta
173 nformatics tools, we show that Dictyostelium discoideum has the highest content of prion-like protein
176 at control the developmental programme of D. discoideum, highlighting the central role of cAMP in the
177 KrsB interacts genetically with another D. discoideum Hippo/MST homolog, KrsA, but the two genes ar
179 teins remain soluble and are innocuous to D. discoideum, in contrast to other organisms, where they f
180 the model developmental system Dictyostelium discoideum, in which Ca(2+) plays a role in receptor-reg
181 on occurs in the social amoeba Dictyostelium discoideum, in which some cells die to form a stalk that
182 ife cycle of the social amoeba Dictyostelium discoideum includes a multicellular stage in which not n
183 PtdInsP(3)-binding proteins in Dictyostelium discoideum, including five pleckstrin homology (PH) doma
185 main and the evidence for TPS function in D. discoideum indicate that the TPS genes mediate lineage-s
186 behavior of the model organism Dictyostelium discoideum indicate the biocompatibility of the function
187 advantage in the amoebal host Dictyostelium discoideum, indicating that the protein family may modul
188 ith starvation, the amoebae of Dictyostelium discoideum initiate a developmental process that begins
190 gregation of the social amoeba Dictyostelium discoideum into a multicellular slug is known to result
192 The microbial soil amoeba Dictyostelium discoideum is a model system for the study of social evo
200 psulation of prespore cells of Dictyostelium discoideum is controlled by several intercellular signal
201 he genome of the social amoeba Dictyostelium discoideum is known to have a very high density of micro
202 ort that a Cdk8 homologue from Dictyostelium discoideum is localized in the nucleus where it forms pa
205 te and define social interactions between D. discoideum isolates, thus providing a conceptual framewo
208 ed for cellular ion imaging in Dictyostelium discoideum live cells but spontaneous dye loss resulted
211 we show that WASH coats mature Dictyostelium discoideum lysosomes and is essential for exocytosis of
212 a genetic interaction between Dictyostelium discoideum mek1, smkA (named for its role in the suppres
213 ng member), Homo sapiens RNF4, Dictyostelium discoideum MIP1 and Saccharomyces cerevisiae Slx5-Slx8.
215 el of the contraction phase of Dictyostelium discoideum motility with an emphasis on the adhesive pro
218 One such residue is Ser236 (Dictyostelium discoideum myosin II numbering) which was proposed to be
219 e show that in the nonmetazoan Dictyostelium discoideum, myosin II localizes apically in tip epitheli
220 associated Burkholderia isolates colonize D. discoideum nonfarmers and infectiously endow them with f
223 lls, including neutrophils and Dictyostelium discoideum, orient and move directionally in very shallo
224 analysis revealed that cAMP signalling in D. discoideum originated from a second messenger role in am
225 n this study we identified the Dictyostelium discoideum ortholog of the adaptor protein AP180 and cha
226 rize mutations in the putative Dictyostelium discoideum orthologues of budding yeast genes that are i
227 only partially restored aggregation of a D. discoideum pdsA-null mutant, but was more effective at r
230 Remarkably, another PPK in Dictyostelium discoideum (PPK2) is an actin-related protein (Arp) comp
231 lug stage of the social amoeba Dictyostelium discoideum produce ETs upon stimulation with bacteria or
233 that, in contrast to observations made in D discoideum, PTEN-null Jurkat T cells exhibited potent ch
234 this study, PKAR and PDE from Dictyostelium discoideum (RD and RegA, respectively) were used as a mo
235 dicates that the social amoeba Dictyostelium discoideum recognizes distinctions between Gram(-) and G
236 ediction for the social amoeba Dictyostelium discoideum; relatedness in natural wild groups is so hig
237 entiation in the social amoeba Dictyostelium discoideum relies on a sequence of events that is indepe
239 ement of volatile terpenes in cultures of D. discoideum revealed essentially no emission at an early
241 such as Ciona intestinalis and Dictyostelium discoideum, revealed the presence of membrane-linked end
243 ings identified the slime mold Dictyostelium discoideum's CISD proteins as the closest to the ancient
244 sapiens, Arabidopsis thaliana, Dictyostelium discoideum, Saccharomyces cerevisiae, Escherichia coli a
245 We show that, unexpectedly, Dictyostelium discoideum SCAR knockouts could still spread, migrate, a
246 he "turbine wave." Herein we argue that a D. discoideum scroll or concentric wave territory containin
248 Although intravesicular pH levels in D. discoideum show small acidic changes with the expression
249 periments on the social amoeba Dictyostelium discoideum show that the origins of lineage bias in this
251 terologous expression, all nine TPSs from D. discoideum showed sesquiterpene synthase activities.
254 Burkholderia inside and outside colonized D. discoideum spores after fruiting body formation; this ob
256 ogenomic approach we have determined that D. discoideum TalA/B and the animal talins are related by d
257 behaviors in the social amoeba Dictyostelium discoideum, testing whether these genes experience rapid
258 is review is one discovered in Dictyostelium discoideum that becomes an actin-like fiber concurrent w
259 er" clone of the social amoeba Dictyostelium discoideum that carries and disperses bacteria during it
260 tified a new protein kinase in Dictyostelium discoideum that carries the same conserved class of "alp
261 ysis of the isolated MTBD from Dictyostelium discoideum that demonstrates the coiled-coil beta(+) reg
263 n Elmo-like protein, ElmoA, in Dictyostelium discoideum that unexpectedly functions as a negative reg
264 model for cAMP oscillations in Dictyostelium discoideum, the cell-cycle data for Saccharomyces cerevi
265 psulation in the social amoeba Dictyostelium discoideum, the metabolic profile and other potential fu
268 mycetozoan eukaryotes such as Dictyostelium discoideum This social amoeba kills bacteria via phagocy
269 esis in the social soil amoeba Dictyostelium discoideum Through genome sequencing, we successfully id
270 part of a regulatory network that allows D. discoideum to elicit specific cellular responses to diff
273 3) is not only unnecessary for Dictyostelium discoideum to migrate toward folate, but actively inhibi
274 In this paper, we exploit Dictyostelium discoideum to uncover a novel role for PARylation in reg
275 we employ a simple eukaryote, Dictyostelium discoideum, to demonstrate distinct effects of loss of I
277 mechanism shows structural specificity as D. discoideum transformants that expel chloroquine do not e
279 he closed state based on the structure of D. discoideum UMP/CMP kinase aids to rationalize the substr
280 ously reported for the similar Dictyostelium discoideum UMP/CMP kinase reveals the conformational cha
286 ling network for chemotaxis in Dictyostelium discoideum We identified a negative regulator of Ras sig
287 reen for chemotaxis mutants in Dictyostelium discoideum, we identified a loss-of-function mutation, d
288 ng a forward genetic screen in Dictyostelium discoideum, we identified the Ste20 kinase KrsB, a homol
290 late multicellular development stages of D. discoideum when migrating slugs differentiate into fruit
291 munication in the social ameba Dictyostelium discoideum when the solitary cells aggregate to form mul
292 ect on the accumulation of chloroquine by D. discoideum, whereas forms of PfCRT carrying a key charge
293 nipulated in the social amoeba Dictyostelium discoideum, which allows us to test and confirm the two
295 his evolutionary hypothesis in Dictyostelium discoideum, which forms multicellular fruiting bodies by
296 hibitor (EC(50) >/= 50 muM) in Dictyostelium discoideum, while the strongest interactant was found to
299 a previously unrecognized PPK (DdPPK2) in D. discoideum with the sequences and properties of actin-re
300 tide-binding site of wild-type Dictyostelium discoideum (WT) myosin and a construct containing a sing
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