ライフサイエンスコーパス: disconnection

1 ("ipsilateral") or in opposite hemispheres ("disconnection").

2 teral ablations of these regions (functional disconnection).

3 lation in the Fas death pathway after target disconnection.

4 and especially in patients with hemispheric disconnection.

5 between synaptic dysfunction and functional disconnection.

6 se from cortical damage or from white matter disconnection.

7 described as precursors of glomerulotubular disconnection.

8 e lost through a process of glomerulotubular disconnection.

9 of 8 mm/d and reach lengths of 10 cm without disconnection.

10 block corresponded to segmental PV-LA muscle disconnection.

11 mes, every 30 mins after a 30-sec ventilator disconnection.

12 rain structures versus corticocortical tract disconnection.

13 of stream-aquifer systems from connection to disconnection.

14 defined as post-stroke necrosis or cortical disconnection.

15 powerful and generally useful retrosynthetic disconnection.

16 L-6), depressed mood, and feelings of social disconnection.

17 ses in depressed mood and feelings of social disconnection.

18 ses in depressed mood and feelings of social disconnection.

19 es in neural dynamics result from structural disconnection.

20 onset as a method to standardize the axonal disconnection.

21 ic increase in both provascular and vascular disconnections.

22 define the loci of potential retrosynthetic disconnections.

23 zing complex molecules using non-traditional disconnections.

24 mple molecules and providing novel synthetic disconnections.

25 werful concept of prioritized strategic bond disconnections.

26 huffle mechanisms through gliding four-layer disconnections.

27 First, using an alternative disconnection, a hemiketal conjugate addition to a napht

28 mus (CTI) ablation (group 1, n=49) or PV-LAJ disconnection alone (group 2, n=59).

29 Neither sensory stimulation nor disconnection alone generated significant eyeblink respo

30 In patients with both AFL and AF, PV-LAJ disconnection alone may be sufficient to control both ar

31 Moreover, these disconnections also each reduced responding and motivati

32 eed, the neurocognitive correlates of social disconnection and connection may be important mediators

33 We conclude that segmental muscle disconnection and differential muscle narrowing at PV-LA

34 We used disconnection and neuroanatomical techniques to reveal t

35 ng steps, and finally kinetically controlled disconnection and release of the mature natural product.

36 ns presented are organized according to bond disconnections and attendant synthetic methods.

37 Here we combined functional disconnections and electrophysiological recordings of th

38 oy typical as well as Umpolung types of bond disconnections and have served as the key step in severa

39 ent and reacquisition we used a chemogenetic disconnection approach and show that silencing either th

40 -dependent manner, we used a pharmacological disconnection approach whereby dopamine signaling was bl

41 Using a selective disconnection approach, we reveal that D1 and D2 recepto

42 y that releases CRF was investigated using a disconnection approach.

43 recover neurological deficits caused by axon disconnection are extremely limited.

44 In planning organic syntheses, disconnections are most often made adjacent to functiona

45 d its relation with the exhibited functional disconnections are very poorly understood.

46 as the presence of neurofibrillary tangles, disconnection, as well as compensation processes.

47 persensitivity is associated with functional disconnection (asynchrony) between the thalamus and cort

48 This disconnection attenuated cue-induced reinstatement of co

49 The disconnection between a reaction's development and the q

50 aken together, these observations indicate a disconnection between aggresome formation and apoptosis,

51 n persons with schizophrenia could involve a disconnection between an "intention center" and a "monit

52 mulations indicated that this delay caused a disconnection between attenuation of the antiviral respo

53 There is a disconnection between biochemical recurrence and progres

54 l pathways in an animal model to address the disconnection between brain regions as a mechanism for w

55 ey can help buffer the effects of hydrologic disconnection between catchments and lakes but at the co

56 Therefore, it was hypothesized that disconnection between cerebral hemispheres would disrupt

57 To investigate the disconnection between observed CD8 T-cell responses and

58 activity of CXCR4, further demonstrating the disconnection between physiological and pathological act

59 anent impairment of sensory functions due to disconnection between the peripheral and central nervous

60 icit indicates a context-specific functional disconnection between the prefrontal cortex and the supp

61 These results reveal a clear disconnection between the presence of intervening sequen

62 ction of the basal ganglia motor circuit and disconnection between the rostral supplementary motor ar

63 lance due to MS appears to be related to the disconnection between the spinal cord, cerebellum, and c

64 eferential processes (OFC, PCC), but also to disconnection between these regions as well as with the

65 Disconnections between in vitro responses and those obse

66 In contrast, disconnections between the BLA and PFC increased choice

67 of basal ganglia motor circuit together with disconnections between the rostral supplementary motor a

68 tivity of those tasks to prefrontal-temporal disconnection by adding specific temporal components to

69 ion for death receptor pathways after target disconnection by axotomy vs. disease progression.

70 lly in the OFC or generated an OFC-amygdala "disconnection" by pairing unilateral OFC Bdnf knockdown

71 This concept of developmental disconnection can accommodate the specific neurobehavior

72 , immature defenses, and over-connection and disconnection cognitive schemata than comparison subject

73 al AFL were randomly assigned to have PV-LAJ disconnection combined with cavotricuspid isthmus (CTI)

74 sented a selective bilateral parietotemporal disconnection, compared with GRN- patients.

75 Failure to account for this spatial disconnection could lead to potentially misleading concl

76 ries of case studies, we found that inferred disconnections could explain enhanced hand-grip-related

77 We used a crossed-disconnection design in which monkeys received amygdala

78 nveyed to the afferents, and this functional disconnection did not support the redox hypothesis of O(

79 PFC-NAc disconnections did not affect choice but did increase ch

80 ain injury (TBI) is a pre-eminent structural disconnection disorder whereby traumatic axonal injury d

81 stration of linear block, and pulmonary vein disconnection during the initial AF procedure.

82 --> 10 are pseudopericyclic with two orbital disconnections each, whereas the 13 --> 14 and 15 --> 16

83 Mitigating the risk by partial disconnection endangers their functionality.

84 First, using a disconnection experiment, we show that the BLA and dopam

85 In contrast, monkeys that sustained MDm disconnection failed to adjust their object choices.

86 L-6 were correlated with increases in social disconnection for females but not for males.

87 These results provide a new retrosynthetic disconnection for the construction of enantioenriched ci

88 This catalytic reaction provides a new disconnection for the convergent synthesis of tertiary a

89 This finding provides a novel disconnection for the synthesis of pyridine-containing a

90 l and heteroaryl systems, representing a new disconnection for the synthesis of this versatile moiety

91 ease of thalamus centrality results from its disconnection from a widespread set of cortical and subc

92 red response inhibition, which may be due to disconnection from cingulate and supplementary motor are

93 parahippocampus showed evidence of transient disconnection from cortical brain regions involved in me

94 ageous outcome probably being related to its disconnection from crucial language processing pathways.

95 stered once every 4 weeks, immediately after disconnection from FU, at a dose of 135 mg/m(2) over 72

96 f immersion in nature, and the corresponding disconnection from multi-media and technology, increases

97 t conditions of internal node failure due to disconnection from nodes within its own network.

98 neglect and amnesia, whereas their selective disconnection from relevant unimodal areas elicits modal

99 ynaptic VAChT and Chrna2 was correlated with disconnection from Renshaw cells as well as major struct

100 fferent sprouting but is associated with the disconnection from the peripheral target since its expre

101 Although not perceived, the blink-induced disconnection from the visual environment leads to a los

102 Aergic interneurons becoming "dormant" after disconnection from their excitatory synaptic inputs, whi

103 anner that does not result in their death or disconnection from their targets but nonetheless alters

104 the ipsilateral (control) or contralateral (disconnection) hemisphere.

105 Using a new bond disconnection, here we report a concise synthesis of the

106 It features a unique strategy for the key disconnection, highlighting a modified Negishi carboalum

107 getic failure, leading to axonal failure and disconnection; however, this mitochondrial damage may al

108 This finding supports the disconnection hypothesis of unilateral neglect and has i

109 We propose a disconnection hypothesis, wherein focal vascular damage

110 adequate neural network, consistent with the disconnection hypothesis.

111 We suggest that prefrontal-temporal disconnection impairs a wide variety of learning tasks b

112 te an implication of caudal interhemispheric disconnection in chronic neglect.

113 cquired alexia is mirrored by its functional disconnection in developmental dyslexia.

114 acidic conditions is an entrenched synthetic disconnection in organic chemistry.

115 matory cytokines, depressed mood, and social disconnection in response to an inflammatory challenge.

116 esults confirm a key role of fronto-parietal disconnection in the emergence and chronic persistence o

117 rosis (MS) that might result from functional disconnection in the frontocerebellar loop.

118 understanding the role of peripheral target disconnection in the pathogenesis of ALS.

119 ction after ACoA aneurysmal rupture) or to a disconnection in the ventromedial circuits from distant

120 vanishes when anesthetics produce functional disconnection in this posterior complex, interrupting co

121 eories of synaptic plasticity applied to the disconnection in visual cortex of the closed eye in mono

122 The key disconnections in our synthetic approach include an enan

123 paspaline present a series of new synthetic disconnections in preparing steroidal natural products.

124 ibed herein outline complementary conceptual disconnections in the arena of steroid natural product s

125 x catalysis has redefined the available bond disconnections in the synthetic arsenal.

126 Pseudocoarctate transition states exhibit disconnections in the topology of orbital overlap and do

127 reating CNS injuries characterized by axonal disconnection including spinal cord injury.

128 on, the mSOD1 facial nucleus displays target disconnection-induced gene expression changes that mirro

129 Melancholia was characterized by a pervasive disconnection involving anterior insula and attentional

130 ognition, it is likely that glomerulotubular disconnection is an underappreciated mechanism in the pr

131 roblem for movement of the critical point of disconnection is established for an analytical solution

132 The scope of this previously unknown bond disconnection is highlighted through the development of

133 We propose that disconnection is mediated by a change in the physical pr

134 This disconnection is sometimes thought to be the consequence

135 white matter damage may induce a functional disconnection leading to a dissociation of regional cere

136 f localized but connected specialized areas, disconnection leads to dysfunction.

137 ial attention and inhibitory control using a disconnection lesion approach.

138 The disconnection lesion led to both impulsive and compulsiv

139 Iowa Gambling task, we used a contralateral disconnection lesion procedure to assess whether functio

140 Monkeys that sustained NA disconnection, like controls, showed robust shifts in ob

141 C on OFC-BLA interactions using a functional disconnection manipulation.

142 pulmonary vein-left atrial junction (PV-LAJ) disconnection may eliminate both arrhythmias.

143 Splenial disconnection may prevent fronto-parietal networks in th

144 with clinical symptoms in vivo and test the disconnection mechanism directly in cognitive disorders.

145 onist muscimol into ventral pallidum (i.e., "disconnection" methods) also impaired response output, i

146 Following PFC-IT disconnection monkeys were severely impaired at reacquir

147 ysfunction (n = 22), and those with callosal disconnection (n = 7).

148 ysfunction (n = 22), and those with callosal disconnection (n = 7).

149 There were 6 telemedicine disconnections, none of which lasted longer than 60 seco

150 onalized aryl ring, this constitutes a novel disconnection of a pharmaceutically important scaffold.

151 on bond forming cycles that enable a modular disconnection of a target structure into cellular buildi

152 date, to study the consequences of complete disconnection of abdominal vagal afferents on innate anx

153 This behavior is disrupted by the disconnection of amygdala pathways to the lateral hypoth

154 n of the uncinate may represent insufficient disconnection of an anterior temporal epileptogenic netw

155 recognition impairment and (2) the degree of disconnection of association fiber tracts [inferior long

156 Disconnection of brainstem pathways reduced the total nu

157 reversible-covalent chemistry to prompt the disconnection of chemical bonds and the formation of new

158 Disconnection of cognitively important processing region

159 Destruction or disconnection of discrete left extrasylvian and perisylv

160 symptomatic mice show significant functional disconnection of dMSNs from motor cortex without changes

161 nigrostriatal lesions induced a significant disconnection of dMSNs from the motor cortex.

162 After disconnection of fixtures and abutments, microbial sampl

163 After disconnection of fixtures and abutments, microbial sampl

164 Further dilution induces a functional disconnection of light-harvesting complex (LHC) II from

165 These findings provide a mechanism for disconnection of long-distance pathways, excessive conne

166 Chemogenetic disconnection of monosynaptic glutamatergic vCA1 to mPFC

167 fter traumatic brain injury results from the disconnection of network hubs by traumatic axonal injury

168 and/or amplify neurodegeneration-associated disconnection of neuronal circuitries.

169 er-value food; monkeys with crossed surgical disconnection of OFC and the amygdala did not.

170 ered by cytokines/growth factors produced by disconnection of peripheral nerve fibers from their cell

171 rontal function in monkeys have shown that a disconnection of prefrontal cortex from inferior tempora

172 The increase in alpha activity and the disconnection of SI from frontoparietal areas are likely

173 The disconnection of striatopallidal neurons from motor comm

174 s of this lesion are caused primarily by the disconnection of temporal cortex from ascending inputs f

175 , True Blue labeling demonstrated anatomical disconnection of the accumbens, FS, substantia innominat

176 onsated) food, monkeys with crossed surgical disconnection of the amygdala and OFC did not.

177 ablished structural connectivity to simulate disconnection of the amygdala.

178 ntralateral side, demonstrating satisfactory disconnection of the ascending brainstem pathways.

179 Disconnection of the BA and the NAccSh was just as effec

180 s found that with concurrent pharmacological disconnection of the cerebellar cortex and intense senso

181 Reversible disconnection of the cerebellar cortex at this time conf

182 tus nucleus was then examined via reversible disconnection of the cerebellar cortex.

183 The surgical disconnection of the cerebral hemispheres creates an ext

184 level of presynaptic activity of the rate of disconnection of the closed eye in monocular deprivation

185 owledge can be used to assess stroke-induced disconnection of the cortical motor system and better in

186 ptogenesis and suggest a state of functional disconnection of the epileptic focus from other cortical

187 cer uptake during a seizure, with a relative disconnection of the epileptogenic temporal lobe in the

188 urthermore, we show that only the electrical disconnection of the ESI probe from the FFE-MS transfer

189 The synthesis was based on the disconnection of the final structure into four building

190 in the default network including functional disconnection of the hippocampal formation.

191 ted that these correlations result from some disconnection of the hippocampus from the thalamus, sept

192 In a subsequent experiment, disconnection of the HPC from the NAc shell using unilat

193 Contralateral, but not ipsilateral, disconnection of the IC and NAc core disrupted outcome d

194 s strategy features a counterintuitive early disconnection of the lactone subunit to a polycyclic eno

195 as predicted that such lesions may result in disconnection of the lateral and medial frontal cortices

196 [14C]DG autoradiography indicated functional disconnection of the lateral preoptic area and SI/MA.

197 tal dyslexia, suggesting that the anatomical disconnection of the left angular gyrus from other brain

198 prior to the onset of chlorosis, namely the disconnection of the LHCI antenna from photosystem I (PS

199 nt investigation found that inactivation and disconnection of the medial prefrontal cortex and basola

200 Disconnection of the MFB from the inferior temporal cort

201 and mitochondrial [Ca2+] signals, indicating disconnection of the mitochondria from the [Ca2+]c signa

202 rom alcohol was associated with a functional disconnection of the mPFC and CeA but not mPFC and nucle

203 acological manipulations as well as surgical disconnection of the olfactory bulb serve to quell the b

204 Conversely, inactivation and disconnection of the orbitofrontal cortex and amygdala l

205 we have similarly observed that a functional disconnection of the PF-posterior dorsomedial striatal p

206 RF neurons in the mPFC during withdrawal and disconnection of the PFC-CeA pathway may be critical for

207 Disconnection of the portacaval shunt by left renal vein

208 Ablation end point was electrical disconnection of the pulmonary veins (PVs).

209 Disconnection of the two pathways during PIT also reveal

210 reduced ureteric bud branching, and delayed disconnection of the ureter from the common nephric duct

211 eceived a standard suctioning procedure with disconnection of the ventilator (20 secs, 14 F catheter,

212 Lastly, disconnection of the white matter tracts connecting fron

213 IT) in the other, thus completing a surgical disconnection of these 2 regions, yielded an impairment

214 Disconnection of these cortices in DH-compromised animal

215 ontrol monkeys, rhesus monkeys with surgical disconnection of these two structures, achieved by cross

216 econd-order conditioning, we also found that disconnection of this circuitry had no effect on the abi

217 Disconnection of this interface is thought to release co

218 ral (LA) nuclei of the amygdala (AMY) and by disconnection of this region and lateral hypothalamus (L

219 This disconnection of trends suggests that perforated and non

220 opography was predominantly subcortical, and disconnection of white matter tracts critically contribu

221 Functional and structural disconnections of cortical networks may underlie various

222 Interestingly, disconnections of the VH from either the BA or PL elimin

223 This may result in a progressive "disconnection" of widely distributed neural networks tha

224 lobal and regional abnormalities as well as "disconnections" of specific cerebral circuits.

225 prefrontal-inferotemporal (PFC-IT) cortical disconnection on two recognition memory tasks, a "consta

226 ngement is pseudopericyclic with two orbital disconnections-one involving the nitrogen lone-pair orbi

227 Similar disconnections or gaps were observed in the provasculatu

228 shuffle mechanisms through gliding two-layer disconnections or pure-shuffle mechanisms through glidin

229 In Experiment 3, a functional disconnection paradigm was used to further examine the i

230 erspectives positing that a corticocortical "disconnection" partly explains cognitive aging.

231 al group could not, indicating that BLA-pDMS disconnection prevented the acquisition of the new R-O a

232 possible neural substrate for the functional disconnection previously described in these patients, an

233 these 13 patients underwent a repeat PV-LAJ disconnection procedure and were cured.

234 aine-seeking habit by using an intrastriatal disconnection procedure that combined a selective, unila

235 The final experiment used a disconnection procedure to assess more directly whether

236 Here, we used an anatomical asymmetrical disconnection procedure to demonstrate that an interacti

237 When a functional disconnection procedure was used to disrupt the interact

238 A disconnection procedure was used to test whether the hip

239 tance of the NAc-S to VP-m pathway we used a disconnection procedure, using asymmetrical inactivation

240 , to test this, developed a novel sequential disconnection procedure.

241 triatal loop, we used a neuropharmacological disconnection procedure.

242 ect discrimination task, the same functional disconnection protocol with MUS did not affect the perfo

243 We have defined a set of retrosynthetic disconnections representing robust reactions, amenable f

244 Furthermore, white matter disconnections resulting from damage along the superior

245 We show that this disconnection selectively decreased drug-seeking behavio

246 We found that the disconnection severely impairs serial reversal learning

247 Specifically, monkeys with functional disconnection showed less of a difference in error rates

248 Functional disconnection significantly affected performance in both

249 e stream-aquifer system can reach a critical disconnection state when the horizontal hydraulic gradie

250 g, viral-mediated gene silencing, functional disconnection strategies, pharmacologic rescue, and desi

251 This disconnection strategy benefits from the use of a simple

252 isoxazole components and represents a unique disconnection strategy for the synthesis of functionaliz

253 tructure have been synthesized by means of a disconnection strategy whereby the appropriate thiols we

254 Subsequent disconnection studies revealed that disruption of top-do

255 Other techniques of disconnection, such as multiple subpial transection, and

256 major interhemispheric commissure, lack the disconnection syndrome classically described in callosot

257 disease (AD), which has been suggested as a disconnection syndrome manifested by the disruption of w

258 hypothesis of the existence of an underlying disconnection syndrome that causes clinical symptoms to

259 This loss leads to a hippocampal disconnection syndrome that drives clinical progression.

260 lthough most researchers consider it to be a disconnection syndrome with paroxysms driven by a loss o

261 tria ipsilateral to the lesion constitutes a disconnection syndrome, as it occurs when the hemipontin

262 tria after large pontine stroke represents a disconnection syndrome.

263 , tinnitus can be regarded as a maladaptive 'disconnection' syndrome, which tries to both stabilize i

264 y studies of patients with occipito-temporal disconnection syndromes may help define the functional r

265 tex, implying an increased susceptibility to disconnection syndromes such as Alzheimer disease and sc

266 connections in two different mouse models of disconnection syndromes to demonstrate its utility for c

267 For him, disconnection syndromes were higher function deficits th

268 Beyond its application to classical disconnection syndromes, diffusion tensor magnetic reson

269 gical disorders, referred to collectively as disconnection syndromes.

270 network; and a variable degree of structural disconnection that modulates this change in network func

271 y attributed to the partial temporal-frontal disconnection that this lesion creates, and therefore su

272 han a biomimetic dimerization retrosynthetic disconnection, the anthracenyl ring systems are generate

273 epth in the stream, and at a steady state of disconnection, the maximum hydraulic gradient at the str

274 cation, we describe the changing fortunes of disconnection theory and adapt the general framework tha

275 The target disconnection theory of amyotrophic lateral sclerosis (A

276 were devoting only a few pages to classical disconnection theory.

277 ispheres, even though before her hemispheric disconnection, they appeared as inseparable cognitive en

278 covariance found that the lower severity of disconnection thought disorders in the older patients wa

279 When disconnection times are sufficiently short, there is a s

280 yclization, which constitutes a formal aldol disconnection to form a strained macrocycle.

281 ry, in 1965, an American neurologist brought disconnection to the fore once more in a paper entitled,

282 c reaction examples and may identify the key disconnections to guide retrosynthesis.

283 lly defined neuronal populations and circuit disconnections to identify the pathways involved in the

284 l formulation directly and broaden it beyond disconnections to include disorders of hyperconnectivity

285 ern that this method may overlook structural disconnections to seemingly spared regions and may fail

286 ther ipsilateral (control) or contralateral (disconnection) to the CeN lesion, and given overtraining

287 hypothesis more directly, rats were given a disconnection treatment using contralateral cytotoxic le

288 ncapped glomerulus lesion." Glomerulotubular disconnection was confirmed, but connection remnants bet

289 to the learning of visual sequences, because disconnection was without effect on object-reward associ

290 In order to facilitate the electrical disconnection we used a low conductivity, silica-based E

291 pha), depressed mood, and feelings of social disconnection were assessed hourly.

292 Parameters estimating disconnection were entered in a general linear model to

293 can be altered from hydraulic connection to disconnection when the pumping rate exceeds the maximum

294 The strategy represents a new biocatalytic disconnection, which relies on an omega-TA-mediated aza-

295 the result of 1) an earlier onset of axonal disconnection with a consistent degeneration rate or 2)

296 hat link experiences of social connection or disconnection with health-relevant physiological respons

297 tomatic CAD, which suggests that subcortical disconnection within large-scale cognitive neural networ

298 gnitive dysmetria hypothesis, which posits a disconnection within the CCTCC as a fundamental abnormal

299 t-traumatic amnesia are caused by functional disconnection within the default mode network.

300 hways, leading to strategic cortico-cortical disconnections within the language network.