ライフサイエンスコーパス: discordance

1 gistic regression to determine predictors of discordance.

2 mors and prominent interassay variability or discordance.

3 our laboratory because of an unusual case of discordance.

4 elease assay positive and skin test negative discordance.

5 We aim to find the reasons for this discordance.

6 nd clinical outcome associated with FFR/CFVR discordance.

7 trains with higher levels of interlaboratory discordance.

8 etastasis had any effect on the rate of HER2 discordance.

9 used to determine covariates associated with discordance.

10 itive, IFN-gamma release assay-negative test discordance.

11 taneously were less likely to have very high discordance.

12 ere used to identify factors associated with discordance.

13 immunoreactivity) to assess sources for test discordance.

14 tion offers a plausible explanation for this discordance.

15 PCR gel was identified as the main source of discordance.

16 ral hypotheses were tested to reconcile this discordance.

17 scriptome differences that explained disease discordance.

18 pathogenic variants contributed to residual discordance.

19 de variants-did not contribute to phenotypic discordance.

20 hy, blastoma, gonadal dysgenesis and genital discordance.

21 Three cases of major discordance (3.2%) occurred.

22 Five cases of major discordance (5.0%) occurred (i.e., changes from responde

23 cordant (DeltaBMI >3 kg/m(2), mean length of discordance 6.3 +/- 0.3 years, n = 26) and concordant (D

24 rvention group had lower surrogate-physician discordance (7 [10] vs. 43 [21]), greater comprehension

25 We defined discordance about prognosis as a difference in the physi

26 Physician-surrogate discordance about prognosis occurred in 122 of 229 insta

27 Discordance about prognosis, defined as a difference bet

28 Relevance: In this study, patient-oncologist discordance about survival prognosis was common and pati

29 ruction algorithm affects the DS and whether discordance affects the capability of (18)F-FDG PET to s

30 Because of substantial discordance among calls made by existing sequencing meth

31 Odds of discordance among case and control patients were compare

32 from other processes leading to phylogenetic discordance among different markers requires a well-reso

33 sion and addiction, relatively high rates of discordance among identical twins clearly indicate the i

34 Imprecision in the FC resulted in diagnostic discordance among replicates only for line-sitters, that

35 ives early in development could help discern discordance among stakeholder priorities; facilitate coo

36 There is important discordance among systemic and pulmonary mediators, phys

37 However, apparent discordance among these data has hampered their full uti

38 Discordance analysis compares the predictive power of LD

39 Discordance analysis is a methodological advance that al

40 The advantage of discordance analysis is that the results are not diluted

41 o trends for an association between receptor discordance and either time to treatment failure or over

42 We explored risk factors for CSF discordance and escape in patients presenting with diver

43 Both discordance and escape may be associated with neurologic

44 In multivariate analysis, both CSF discordance and escape were associated with diffuse whit

45 The association between HIV-1 RNA discordance and HIV-associated neurocognitive disorder (

46 ow that these haplotypes have lower genotype discordance and improved imputation performance into dow

47 ney, software that considers both intra-read discordance and soft-clipped tails of long reads (>10,00

48 This discordance argues that osteoblastic assessment provides

49 nd 0.692; all P<0.0001), prevalence of LDL-C discordance as defined by median cut points was 11.6%, 1

50 ge points; we defined very low and very high discordance as differences of +/-14 percentage points.

51 atients or families to accommodate intrateam discordance (as part of the "pas-de-deux"), subsequent d

52 ontrary to the 'so-called' structure-symptom discordance, as well as between fluctuations of knee pai

53 The odds for discordance associated with cirrhosis were of similar ma

54 more true positives while controlling total discordance at a lower level on the simulated data, even

55 Factors associated with very high discordance at baseline included history of end-stage li

56 ancy versus delivery, 20% had IGRA(+)/TST(-) discordance at each time point.

57 However, statistically significant discordance at the 50 copies/mL cutoff was found between

58 Compounding the discordance, Atm mutations in mouse interfere with DNA r

59 iography in general measured similar to CMR, discordance because of limitations in echocardiography t

60 Discordance between absolute CD4 cell count and CD4 cell

61 We defined low and high discordance between absolute CD4 cell count/CD4 cell per

62 Further discordance between ACAID and corneal allograft survival

63 Moreover, we examined the hypothesis that discordance between amyloid biomarker measurements may b

64 antify the associations between apoB and the discordance between apoB and LDL-C or non-HDL-C in young

65 Discordance between atopy and allergic conditions was co

66 We discuss an important risk for discordance between biodistribution, as typically measur

67 osis prior to cirrhosis were associated with discordance between CD4 count (CD4N) and CD4 percentage

68 Conclusion Despite discordance between clinical assessment of resection ext

69 The objective of this study was to assess discordance between commercially available tests for lat

70 The mean (SD) discordance between DCT and GAT measurements was -3.3 (2

71 tween animal models and human diseases, high discordance between DNA and protein expression data and

72 The HGT creates widespread discordance between evolutionary histories of different

73 is study, we provide further evidence of the discordance between ex vivo-isolated and in vitro-cultur

74 Discordance between FFR and CFVR occurred in 31% and 37%

75 Discordance between fractional flow reserve (FFR) and co

76 ) binding was not increased, demonstrating a discordance between functional and binding site effects.

77 ent article, we highlight potential areas of discordance between Good Clinical Practice guidelines an

78 We found instances of discordance between HUMARA results and those obtained by

79 scans was challenging, with a higher rate of discordance between interpreters than in AD and control

80 sisting of variants with naturally occurring discordance between levels of LDL-C and apoB was associa

81 Recent discordance between measured levels of serotypes of deng

82 the present study, we examine the causes of discordance between mitochondrial (mtDNA) and nuclear DN

83 e to generation time may help to resolve the discordance between molecular and paleontological estima

84 We reviewed discordance between molecular and phenotypic DST for INH

85 In this review, we will discuss the discordance between mutational homogeneity and clinical

86 There is significant patient-level discordance between non-HDL-C and LDL-C percentiles at l

87 Discordance between Op and ACL for final TIMI flow (0 to

88 The referring physician classified discordance between PET/CT and PET/MR observations eithe

89 g with autoradiography demonstrated areas of discordance between plaque presence and tracer uptake.

90 This study sought to examine patient-level discordance between population percentiles of non-high-d

91 years; 325 [79.1%] female), 123 (29.9%) had discordance between preoperative 4D-CTs and intraoperati

92 Discordance between preoperative 4D-CTs and intraoperati

93 nd disease was most strongly associated with discordance between preoperative 4D-CTs and intraoperati

94 Retrospective data suggest that discordance between primary and metastatic lesions leads

95 duodenum, acquired insertions with a similar discordance between primary and metastatic sites.

96 We have previously demonstrated sequence discordance between proviral and plasma gag clones in ES

97 There was no significant discordance between routine staging and PET/CT staging (

98 The observed discordance between state-of-the-art VC pipelines, howev

99 This large clinical study has shown that discordance between symptoms and signs in DED is an indi

100 Predictors of discordance between symptoms and signs in DED, defined b

101 To investigate predictors of discordance between symptoms and signs in dry eye diseas

102 analysis was used to test the association of discordance between symptoms and signs with a wide range

103 One in 3 patients had >/=25 percentile units discordance between TC/HDL-C and LDL-C, whereas 1 in 4 h

104 C, whereas 1 in 4 had >/=25 percentile units discordance between TC/HDL-C and non-HDL-C.

105 explained >86% of the variance in percentile discordance between TC/HDL-C versus LDL-C and non-HDL-C.

106 A 21% discordance between technically and nontechnically compe

107 re is uncertainty regarding how to interpret discordance between tests for latent tuberculosis infect

108 However, there is discordance between the 2 measures in profiling hospital

109 We evaluated factors associated with discordance between the absolute CD4 cell count and the

110 ium at risk was estimated by determining the discordance between the areas of left ventricular (LV) w

111 In patients with preserved LVEF, a discordance between the AVA (in the severe range) and th

112 microscale dosimetry and fails to solve the discordance between the BED50 values.

113 mic 3-dimensional structures with a range of discordance between the epicardial and the endocardial t

114 Interestingly, concordance/discordance between the genetic factors driving allergic

115 Discordance between the guidelines, the AUC, and the NCD

116 There was a discordance between the hematologic response and the N-t

117 The discordance between the high prevalence of mutations in

118 Genetic analyses revealed discordance between the mitochondrial and nuclear data.

119 However, there is discordance between the mutation patterns observed in HI

120 laboratory were the reasons for the observed discordance between the performance of computational too

121 ovide additional predictive information when discordance between the scoring systems exists.

122 g these patient samples, genotype assignment discordance between the two methods was found in 0.5% of

123 Discordance between them may reflect differences in magn

124 measures and patient satisfaction, we noted discordance between these measures (kappa statistic <0.2

125 ysis centers because factors associated with discordance between these metrics might inform intervent

126 There is discordance between trainee perceptions of quantity and

127 e associated with more pronounced expression discordance between twin pairs and less stable gene expr

128 Discordance between visual acuity and visual field in in

129 These observations suggest that discordance between VL and CD4 count can occur in the pr

130 This study sought to analyze the discordances between expert fetal cardiac diagnosis and

131 Discordances between NucAmino and LAP occurred in 512 (1

132 For live births, we identified 368 (29.3%) discordances between pre- and post-natal diagnoses.

133 ria for further review: 11 studies reporting discordances between primary tumors and metastases in ex

134 the main cause of mito-nuclear introgression discordance but cannot dismiss the possible role of sele

135 On a smaller scale, TC/HDL-C > non-HDL-C discordance by >/=25 percentile units increased from 6%

136 Main Outcomes and Measures: We ascertained discordance by comparing patient and oncologist ratings

137 nt of myocardium at risk estimated from this discordance correlated well with myocardium at risk meas

138 Evolutionary discordance could explain this association.

139 es identified two situations where intrateam discordance creates moral distress: 1) situations involv

140 Instead of adhering to the concordance-discordance dichotomy, comparative phylogeography needs

141 Despite widespread phylogenetic discordance due to the sorting of ancestral variation, w

142 partum TB, of which three had IGRA(+)/TST(-) discordance during pregnancy.

143 d neuroimaging variables associated with CSF discordance/escape were identified using multivariate lo

144 blems should raise suspicion of possible CSF discordance/escape.

145 Thus, discordance existed between MPS and the mammalian target

146 Discordance exists between the research evidence and aca

147 There was negative/positive discordance for 15 of 170 (8.8%) participants by QFT-GIT

148 nozygotic; 33 dizygotic) with concordance or discordance for ADHD symptomatology assessed at 8, 10, a

149 gn comparing siblings with varying degree of discordance for height (reference was the taller sibling

150 of twin pairs on the basis of their >30-year discordance for physical activity.

151 mean age 9.7, s.d. 1.9 years), we found that discordance for the disorder is mirrored by differing di

152 Pregnant women with IGRA(+)/TST(-) discordance had less IFN-gamma and IL-2 than those with

153 th IGRA(+)/TST(+), women with IGRA(+)/TST(-) discordance had significantly less IFN-gamma (1.85 vs. 3

154 The discordances had a negative impact on late care strategy

155 However, discordances have been noticed in summary conclusions in

156 In particular, several cases of mito-nuclear discordances have been reported for a wide range of orga

157 HPV test result discordance identified a cluster of low-risk HPV infecti

158 Causes of initial discordance in ACMG-AMP classifications were identified,

159 Psychiatric and Substance Use Disorders for discordance in age at onset of regular smoking.

160 Discordance in clinical and surveillance classification

161 h season (P = .02) were associated with twin discordance in disease status.

162 There was significant discordance in epitope specificity between BM and matern

163 Discordance in ER, PgR, and HER2 between the primary and

164 tional difficulties were strongly related to discordance in experiences with MD.

165 m the recent identification of a significant discordance in genotype-phenotype association, we have r

166 heterogeneity of breast cancer and possible discordance in HER2 status between primary tumors and di

167 urocognitive performance was associated with discordance in HIV-1 RNA detection between plasma and CS

168 The most common anatomic locations for discordance in interpretation were the intraorbital opti

169 Discordance in methods may translate into differences in

170 tion and disability in young adults, disease discordance in monozygotic twins has been interpreted to

171 iation in the brain as an explanation of the discordance in monozygotic twins, a proximate cause of m

172 ing of HIV-1 RNA by TaqMan 2.0 confirmed the discordance in only 28 of the 87 samples.

173 Discordance in parents' mood states and in their illness

174 The surprising discordance in phenotypes between SEC23B-deficient mice

175 The discordance in physician self-reports and objective audi

176 explained a small amount of the variance in discordance in QOL.

177 Discordance in risk category classification (<10% or >10

178 on repair (NER) pathway, which may exhibit a discordance in sensitivities to these drugs.

179 EOC that, unlike defective HR, may lead to a discordance in sensitivity to platinum and PARPi, with p

180 Discordance in SHaRe most frequently occurred because hy

181 ed assay on two independent cohorts suggests discordance in the 10% to 20% range with current IHC met

182 Discordance in the diagnosis was documented in 109 (12%)

183 There was discordance in the hospital discharge status (alive or d

184 There is notable discordance in the perception of hirsutism between patie

185 Discordance in the quality of intimate love relationship

186 The discordance in the results of staining for ERCC1 suggest

187 ide of this setting, there is no evidence of discordance in the SEP of donors and recipients that wou

188 data in terms of demonstrating similarity or discordance in tissue compartment distribution patterns.

189 Discordance in variant classification among hypertrophic

190 This article evaluated such discordances in detail.

191 We demonstrate that discordances in mtDNA and NRY haplotypes substantially r

192 riants through extensive phenotyping, reduce discordances in public databases of genes and variants,

193 Factors associated with high or very high discordance, including either end-stage liver disease or

194 Among the 411 patients, 75 (18.2%) had major discordance, including incorrectly localized adenoma on

195 interval [CI], .95-2.96); the odds ratio of discordance increased to 2.66 (95% CI, 1.11-6.40) among

196 isorder is substantial, but monozygotic twin discordance indicates a role for nonheritable difference

197 there is considerable monozygotic (MZ) twin discordance indicating a role for non-genetic factors.

198 The uncorrected discordance IOPDCT - IOPGAT showed a positive correlatio

199 Evidently, discordance is a product of long generation times and mo

200 Here we provide strong evidence that this discordance is better-explained by a convergent molecula

201 erse cardiac events associated with FFR/CFVR discordance is mainly attributable to stenoses where CFV

202 Histologic discordance is most commonly observed between the bone m

203 s on the basis of results of the biopsy, and discordance is not then associated with detrimental effe

204 Latent tuberculosis infection (LTBI) test discordance is poorly understood.

205 Discordance (mainly isolated cerebrospinal fluid amyloid

206 We hypothesized that this discordance may account for the poor MSC engraftment and

207 This discordance may be important in understanding JCV biolog

208 Such discordance may be owing to worse vision in the home tha

209 This discordance may derive from assuming the primary functio

210 This discordance may distort priorities in the research and p

211 Substantial discordance may exist between methods for assessing the

212 This discordance might be ascribed to the existence of a 'hea

213 For 242 of the sequences with discordances, NucAmino produced an alignment that was pr

214 The substantial discordance observed between traditional prognostic mark

215 V shedding may account for the higher method discordance observed with each of these viruses.

216 ination may account for a proportion of test discordance observed.

217 as a non-clinical predictor of TdP despite a discordance of about 30%.

218 ing was performed for the twin pair that had discordance of aortic valve and aortic aneurysm.

219 Discordance of CFVR with FFR originates from the involve

220 We report discordance of changes in nascent transcript and total n

221 earman correlation 0.514-0.596) and there is discordance of detection calls on a subset of miRNAs.

222 To study concordance and discordance of gene and protein expression, we integrate

223 We also found that discordance of HLA alleles was significantly associated

224 We then focus on initial discordance of LI-RADS with American Association for the

225 r the conduction abnormality the greater the discordance of LV filling force with the predominant LV

226 Genomic waves contribute to discordance of PennCNV and MinimumDistance for high cove

227 what mechanisms underlie the concordance or discordance of phenotypic and phylogeographic differenti

228 With discordance of results between primary and metastatic ti

229 Discordance of symptom reporting was more frequently cha

230 aimed to assess the extent of patient-level discordance of TC/HDL-C with LDL-C and non-HDL-C, becaus

231 nature of this recommendation contributes to discordance of variant classification among clinical lab

232 y-four (14.7%) LPs in 22 patients showed CSF discordance, of which 10 (6.1%) LPs in 9 patients repres

233 the same patient and assessed the impact of discordance on patient management and survival.

234 most popular reconciliation methods consider discordance only due to gene duplication and loss (and s

235 ting with diverse neurological problems, CSF discordance or escape was observed in 15%, with treatmen

236 PD-L1 expression discordance or heterogeneity using the diaminobenzidine

237 not APD alternans, the pacing threshold for discordance, or threshold for VF.

238 Discordance-positive (18)F-FDHT lesions were similarly b

239 We observed mito-nuclear discordance possibly stemming from incomplete lineage so

240 Discordance rate between administrative and clinical dia

241 eading to reclassifications that reduced the discordance rate from 20.5% to 10.7%.

242 With a high biopsy discordance rate, our data suggest that renal allograft

243 The aim of this study was to evaluate discordance rates and their clinical implications in the

244 In treatment-naive, noncirrhotic patients, discordance rates around the clinical cutoffs at 4M and

245 Finally, discordance rates around the proposed thresholds in 2 co

246 The HER2 discordance rates differed significantly on the basis of

247 High monozygotic twin discordance rates for common diseases suggest that unexp

248 pecies tree is due to gene tree-species tree discordance rather than parallel substitutions in the ge

249 testing across platforms may be required for discordance reconciliation.

250 Although the diagnosis of discordance relied heavily on histopathology alone in th

251 rue prevalence and clinical ramifications of discordance remain controversial as available data are p

252 %) and 17 of 86 (20%) PERCIST classification discordances, respectively.

253 The discordance seen in some CRT responders between improvem

254 Intrateam discordance served as a key source of distress for all h

255 d lipid testing, the extent of patient-level discordance suggests that TC/HDL-C may offer potential a

256 f TC/HDL-C with LDL-C and non-HDL-C, because discordance suggests the possibility of additional infor

257 , distribution, and proportion of prognostic discordance that is due to patients' knowingly vs unknow

258 Given this discordance, the mechanism of downregulation was investi

259 bines signals from split reads and mate-pair discordance to detect somatic structural variants.

260 DG PET/CT and CTC in the setting of response discordance to establish bone-dominant disease as a tumo

261 , 12.17%-109.61%) and significant interassay discordance using QIF (26.6%).

262 esulting in either cerebrospinal fluid (CSF) discordance (viral load [VL] in CSF 0.5 log10 copies HIV

263 We identified several predictors of discordance warranting further study.

264 High apoB and low LDL-C or non-HDL-C discordance was also associated with Y25 CAC in adjusted

265 In two pairs, discordance was associated with a single traumatic event

266 TST(+)/QFT(-) discordance was associated with age, male sex, black rac

267 Interestingly, HLA discordance was associated with clustering in our predom

268 TST(-)/QFT(+) discordance was associated with older age, previous TB e

269 Discordance was defined as a change in localization or a

270 Discordance was defined as a within-pair difference of a

271 High CD4(+) lymphocyte discordance was defined as higher CD4% relative to CD4N

272 Discordance was defined as LDL-C greater than or equal t

273 Where P was <0.05, discordance was due to detection of more HPV-positive sa

274 Follow-up investigation determined that this discordance was due to the use of two different spectrop

275 Diagnostic discordance was found to be largely caused by perceptual

276 y returned the same phylogeny, but gene tree discordance was high: 37% of gene trees having at least

277 Discordance was highest with a low hybridization signal

278 ble analysis, the odds of having high CD4(+) discordance was increased in persons with significant li

279 Discordance was markedly lower among centers specialized

280 Post-treatment discordance was more frequent in the placebo group, affe

281 Discordance was more than twice as frequent among clinic

282 Discordance was most common when the experimental arm wa

283 Survival discordance was not associated with differences in early

284 Discordance was primarily attributable to the absence of

285 In 65 instances (28%), discordance was related to both misunderstandings by sur

286 Further discordance was resolved with consensus discussion.

287 High/very high discordance was seen in 31% (n = 286), while 35% (n = 32

288 Discordance was substantially more common among nonwhite

289 To understand the QT/TdP discordance, we used quantitative profiling and compared

290 Signatures of phylogenetic discordance were abundant in the genomes of modern cats,

291 l medicine practices, although some areas of discordance were identified.

292 Most discordances were clarified upon high-throughput sequenc

293 The discordances were found to be independent of trial-relat

294 All 12 possible categories of discordances were observed.

295 287 participants, 99 (34.4%) had high CD4(+) discordance, which increased to 76% of 114 participants

296 y transplantation remains debatable owing to discordance with coronary angiography and outcome yields

297 re likely to be recommended chemotherapy, in discordance with NCCN guidelines.

298 However, PVH C-Fos induction is in discordance with the abundant expression of NPY receptor

299 noninvasive prenatal testing results showed discordance with the fetal karyotype.

300 , there was clinically meaningful diagnostic discordance, with the FFR from the pressure wire >0.80 a