ライフサイエンスコーパス: discrete

1 gle-cell regulome data are highly sparse and discrete.

2 categories of emotion are fuzzy rather than discrete.

3 Discrete acoustic sources were sequentially addressed by

4 ependent inter-relationships, with moderate, discrete activation of distinct cell populations by fear

5 Besides discrete active sites, the catalytic activity arising fr

6 ivities from the EAR analysis were linked to discrete adverse outcome pathways to identify potential

7 itionally, the dissolution method produces a discrete Al cluster on a scale suitable for studies and

8 This enables the development of a discrete algorithm to efficiently compute the largest eq

9 ion with new NMR experiments data shows that discrete amino acid networks, termed sectors, control th

10 s specifically to the LD surface, contains a discrete amphipathic alpha-helical targeting sequence, a

11 ings have implications for understanding how discrete amygdalar CRF pathways modulate longer-lasting

12 ng individuals in a sample fractionally into discrete ancestry components.

13 ve and pheromone-treated yeast cells exhibit discrete and asynchronous Ca(2+) bursts.

14 se NCs, which bridges the link between their discrete and collective properties.

15 Both spatially discrete and continuous mechanistic models are considere

16 ted experiences of emotion are structured by discrete and dimensional geometries.

17 okines play a critical role in directing the discrete and gradual transcriptional changes that define

18 ominant hereditary disease in which multiple discrete and irregularly shaped granular opacities are d

19 Before polymerization, particles are discrete and nonconducting, but after polymerization the

20 These data also reveal a temporally discrete and potentially therapeutically amenable functi

21 T nucleation is dramatically up-regulated at discrete and sparse locations within the Golgi.

22 indicative of heterogeneity of functionally discrete and stable differentiation states, or conversel

23 A discrete anti-parallel 1M6N-like dimer was the dominant

24 Discrete areas of flow loss were noted in 37.8% (31/82)

25 2-deficient mice showed iron accumulation in discrete areas of the brain (olfactory bulb, hippocampus

26 pping mode which is important for depositing discrete array of nanodots is found to occur in the rang

27 relationship between dopamine signaling and discrete aspects of cocaine taking and seeking.

28 tions contain sequences that often influence discrete aspects of plant biology.

29 single-channel current recording, we define discrete assembly intermediates and show that the pore i

30 ndTemp (DT) catheter, pigs (n = 6) underwent discrete atrial ablation in a temperature control mode (

31 cted by image segmentation and assignment of discrete attenuation coefficients, which offer limited a

32 These data reveal discrete bands of E2 and E3 cells that may relay informa

33 y the number of interfaces, or the number of discrete beads, in the connection.

34 tilization by using an evolutionary model of discrete binary characters, indicating that substrate us

35 s represent distinct facets of behavior with discrete biological bases is unclear.

36 nd interactions with its protein partners in discrete biological contexts, providing a broad framewor

37 urce of current fluctuations that reflects a discrete blockage current level structure.

38 We propose a multi-component discrete Boltzmann model (DBM) for premixed, nonpremixed

39 tabolism during dormancy appeared to involve discrete but interrelated events.

40 While not readily apparent at birth, discrete cell clusters emerge over the first postnatal w

41 n an unsupervised manner and, in classifying discrete cell cycle stages, we reach a sixfold reduction

42 at specifically target these interactions in discrete cell populations.

43 We identified discrete cell types as well as temporally and spatially

44 ow that individual Cle proteins have adopted discrete cellular functions by interfering with chemotax

45 cal methods to profile RNA expression within discrete cellular populations remains a key challenge in

46 hy, it was shown that M. sedimenti undergoes discrete cellular shifts in response to methane starvati

47 able long time-lapse, live-cell nanoscopy of discrete cellular structures and organelles with high sp

48 This is particularly critical for discrete changes in fate (e.g., life vs. death) for whic

49 either voluntary abstinence (achieved via a discrete choice procedure between drug and palatable foo

50 rats underwent voluntary abstinence (using a discrete choice procedure between methamphetamine and fo

51 We identify two discrete circuits of parvalbumin-positive (PV) neurons i

52 s in distinct circuits in the brain, yet how discrete circuits underlie behavioral subsets of depress

53 r genes in specific motor neuron subsets via discrete cis-regulatory elements.

54 ic structure, binning assembled contigs into discrete clusters is critical.

55 Imprinted genes occur in discrete clusters that are coordinately regulated by sha

56 ource data, as records are often assigned to discrete clusters, even if an assignment is unclear.

57 ate the importance of assessing lifespans of discrete cohorts across repeat studies to capture biolog

58 oints, and classifies Repli-seq signals into discrete combinations of replication signatures.

59 newly clarified role of Bcl11b distinguishes discrete components of commitment, resolving how innate

60 ntages as compared to electronics built from discrete components.

61 These molecules exhibit three discrete conducting states accessed by electrochemically

62 es only the signs of the coefficients of the discrete cosine transform for low-resolution images.

63 e explore the transcriptional basis for four discrete crude oil injury phenotypes in the early life s

64 t the aerogel, while CV deposition created a discrete crust, indicating that CV electrodes were limit

65 Discrete cues can gain powerful control over behavior to

66 swiftly by the synthesis of viral DNA within discrete cytoplasmic foci.

67 r eIF2alpha, which promotes the formation of discrete cytoplasmic inclusions, termed stress granules

68 ause these systems map continuous objects to discrete data.

69 These studies suggest that a discrete DC subset both expands Tregs and suppresses CD8

70 Considering the lack of discrete delineation and continuous spectrum observed, w

71 bling quantitative drug loading, molecularly discrete delivery devices, and a priori knowledge of car

72 therapeutic strategies that account for the discrete disease entities and their plasticity.

73 The ability presented here to produce long, discrete DNA products in an isothermal reaction extends

74 hydrolases are modular enzymes, composed of discrete domains for high-affinity binding to cell wall

75 of how to aggregate continuous exposure into discrete doses can impact the modeled force of infection

76 er synthetic circuits consisting of multiple discrete dye aggregates within a DX-tile.

77 d quantitative live-cell analyses to measure discrete early stages of CME and show how sequential, al

78 he structure and dynamics of even apparently discrete ecological communities.

79 well as numerical simulations of neurons as discrete, elastic rods provide evidence that a balance o

80 rvations of distinct, high-energy, downward, discrete electron acceleration in Jupiter's auroral pola

81 with a continuum phenomenological model and discrete element method simulations.

82 others' social-relational value and moderate discrete emotions across scenarios.

83 Discrete endo,exo-norbornenyl dialkylesters (dimethyl DM

84 ntations support the gradual organization of discrete episodes into structured knowledge.

85 layered volcanic sequence with at least four discrete eruptive events spanning 93 +/- 12 Ma (1416 +/-

86 a distinct ethnic group comparable to other discrete ethnic groups in Africa and Europe, providing a

87 We performed a discrete event simulation to forecast patient characteri

88 mulated the treatment of IF in children in a discrete-event model.

89 ng and duration of high pCO2 exposure (i.e., discrete events at different stages of successional deve

90 ' distributions and population fluctuations, discrete events may be important drivers of space use, s

91 umans automatically segment experiences into discrete events.

92 asis of electroreception and demonstrate how discrete evolutionary changes in ion channel structure f

93 These discrete extreme climatic events can constrain populatio

94 A discrete failure time analysis for multiple events using

95 vioural task, including activity that formed discrete firing fields at particular sound frequencies.

96 formation of an extended fiber assembly into discrete flakes after incorporation of Pt-DA.

97 protein; transient aggregations of RNAs into discrete foci at or near the nuclear membrane triggered

98 emissions from Earth's polar regions, called discrete for their sharply defined spatial configuration

99 Isolation of discrete fractions then allowed excellent separation (by

100 h classes of model compounds isolated within discrete fractions.

101 fterwards, an efficient approach of Embedded Discrete Fracture Model (EDFM) was applied to explicitly

102 than being biased toward terminal process or discrete functional blocks, which suggests extensive evo

103 sttranslational modifications and performing discrete functions as specialized tracks for cargo traff

104 ntally programmed' in the thymus to generate discrete gammadelta T cell effector subsets with distinc

105 ror correction, and the need to compile into discrete gate sets, the necessary computations can be pe

106 9{Si(TMS)3}3PR2] (R: Cy (1), (i)Pr (2)) with discrete Ge-P exo bonds.

107 Thus, we propose that discrete gene mutations in intellectual disability might

108 We identified discrete genetic relationships between ham-1, pig-1 and

109 However, discrete genomic determinants of response to cancer immu

110 These small RNAs originate from discrete genomic loci enriched in TE sequences and displ

111 karyotic DNA replicates asynchronously, with discrete genomic loci replicating during different stage

112 This process operates recurrently at discrete genomic regions and generates driver mutations.

113 examined the effects of CAPs exposure during discrete gestational periods (1: GD0.5-5.5; 2: GD6.5-14.

114 We propose that TDW identifies a discrete global brain activity mode that is regulated by

115 ramics or phase-transforming solids, and the discrete governing equation is shown to approach the pha

116 Assigning individual cells into discrete groups of cell types (gating) involves time-con

117 uous in nature, rather than characterized by discrete groups of similar individuals.

118 ofiles on a set of continuous variables into discrete groups represented by a categorical latent vari

119 In addition, we found a number of discrete groups whose function remains poorly characteri

120 t segregation of tuning responses within any discrete HsOr subfamily.

121 ication of several other reflexes regulating discrete immune functions.

122 Moreover, we found that DCCD mediates discrete intramolecular cross-links of E. coli TatC invo

123 mosomally linked and unlinked, coalesce into discrete intranuclear foci.

124 us, we propose that NMB and GRP may transmit discrete itch information and NMBR neurons are an integr

125 The identification of a discrete JAG1(+) thymic medullary niche enriched for DC-

126 body wall musculature of the trunk into two discrete layers, while most tetrapods expand this patter

127 e crystals can be assembled with two or more discrete layers.

128 switching of the DNA conductance between two discrete levels.

129 y modality, vision or audition, defines four discrete LFC regions.

130 es connecting the AOTU, BU, and EB represent discrete lineages, genetically and developmentally speci

131 analysis of sediment gouge cores established discrete lithostratigraphic units extend across the wetl

132 lower airway microbiomes are associated with discrete local host immune responses, peripheral metabol

133 V) is a pathogenic fish rhabdovirus found in discrete locales throughout the Northern Hemisphere.

134 Many cells localize mRNAs to discrete locations in the cytoplasm.

135 chment of lysine-27 acetylated histone H3 at discrete loci, accompanied by enhanced chromatin accessi

136 n the four neuromeres of the SEZ, as well as discrete longitudinal neuropil domains within each SEZ n

137 netic mechanism underlying the expression of discrete mating strategies in the rock-paper-scissors (R

138 Discrete medullar lesions, confirmed by bioluminescence

139 a a concerted transition state rather than a discrete Meisenheimer intermediate.

140 The organization of the eukaryotic cell into discrete membrane-bound organelles allows for the separa

141 ncurrently, providing the first example of a discrete metallosupramolecular architecture with segrega

142 In total 36 discrete methoxyheteroarenium salts bearing electron-don

143 tary reactions with methane that result in a discrete methyl intermediate where the formal oxidation

144 rged, amphiphilic block copolymers that form discrete micelles at low concentrations and enter a phas

145 ular structure enabling mixing of previously discrete mitochondrial DNA nucleoids.

146 China, we propose an age- and time-dependent discrete model and use the method of non-linear least sq

147 inite-size FLG systems using a novel spatial discrete model that describes both electrostatic interla

148 Here, we present an NMR-guided all-atom discrete molecular dynamics (DMD) platform, iFoldNMR, fo

149 ofiled this unique alkaloid across panels of discrete molecular targets.

150 sections by leveraging an extensive range of discrete monochromatic light sources and allows for an e

151 were explored by analysing a dataset of 100 discrete morphological characters and DNA sequence data

152 ting drug-target interactions and potency to discrete motivational states during a single self-admini

153 er these layers are supplied by anatomically discrete motoneuron pools, we injected tracer into the o

154 well-defined voltage profile-compared to the discrete multiple voltage plateaus observed for a homolo

155 at macrophage surfaces but are organized in discrete nanoclusters, with a mean radius of 71 +/- 11 n

156 ite from the Sudbury impact structure, three discrete nanostructural domains have been isolated yield

157 ed molecules for programmed self-assembly of discrete nanostructures.

158 Originally used to detect discrete neurotoxic damages, TSPO has generally turned i

159 The identification of discrete neutrophil populations, as well as the characte

160 cal structures and leads to the formation of discrete nickel-seamed pyrogallol[4]arene nanocapsules.

161 maps may extend to the implicit encoding of discrete, non-spatial graphs.

162 the transformation mechanism, and we observe discrete nucleation events and sigmoidal nucleation and

163 monodisperse in water and are composed of a discrete number of gold atoms, forming a crystalline gol

164 lecules in the form of short reads, yielding discrete, often highly non-normally distributed gene exp

165 he antennal lobe, each of which represents a discrete olfactory information-processing channel.

166 t, and metal-free method for construction of discrete oligomers with tailored structures and a high g

167 with thiol-maleimide coupling to synthesize discrete oligomers/macromolecules on a gram scale with m

168 NAs are organized into operons consisting of discrete open reading frames (ORFs) in a single polycist

169 that contribute to gating and selectivity in discrete open states.

170 ver the integer numbers corresponding to the discrete orbital and radial momentum components of the l

171 Encoding/decoding off-axis points with discrete orbital angular momentum (OAM) modes is investi

172 Recently, porous solids fabricated from discrete organic cages have garnered much interest due t

173 s class of organic reactions, either between discrete organic molecules or on the pore surfaces of MO

174 Memory reactivation in the model occurs in discrete oscillatory bursts rather than as sustained act

175 sites (P = .0006), and nonvisualization of a discrete ovarian mass (P = .0037) were associated with s

176 The only discrete palpable finding was lumpectomy bed seroma.

177 that reach-to-grasp movements arise from two discrete parietofrontal cortical networks.

178 wheat orthologous gene sequences to compare discrete parts of the Ae. markgrafii genome involved in

179 d that many landscapes comprise a network of discrete patches of habitat.

180 This syndrome has a discrete pathophysiology and differs genetically and cli

181 Both link to discrete pathophysiology: irritability with disruptions

182 he calculated free energy profiles capture a discrete pattern in the rotation of the central gamma-sh

183 amma-aminobutyric acid cotransmission convey discrete patterns of dopamine neuron activity to striata

184 Discrete peaks in the second dimension using the thermal

185 the hypothesis that exposure to PM2.5 during discrete periods of pregnancy results in PTB and LBW.

186 The discrete (phosphinoarenesulfonate)Pd fluoride complex (P

187 es separate the dual activity of BKM120 into discrete PI3K and tubulin inhibitors.

188 g various Ph-like genomic alterations with 4 discrete PI3K pathway protein inhibitors and observed ma

189 s through a unique mechanism that involves a discrete PilZ adaptor protein.

190 ol to identify small molecules that modulate discrete plant functions that could be produced later in

191 rgeted to specific multiprotein complexes at discrete plasmalemmal, sarcoplasmic reticular and myofil

192 membranes and epithelial cell monolayers at discrete points in a sample.

193 maintain stable, contractile connections to discrete points within ECM during cell migration, and pr

194 n-house admixtures as data series instead of discrete points.

195 This work underpins how discrete polyphenic traits in epigenetically metastable

196 IWI2 protein localized to the cytoplasm of a discrete population of multiciliated airway epithelial c

197 A discrete population of smooth muscle cells forms in the

198 tes defined by self-assembled particles with discrete populations of volumes and polyhedral shapes.

199 ectrum of genome diversity(8) or genetically discrete populations(9,10).

200 ons over extensive geographic distances form discrete populations.

201 contribute to beta-cell apoptosis by forming discrete pores that destabilize the cellular membrane.

202 Effects extended beyond discrete predatory events and persisted steadily for 10

203 The mean-field approximation of the discrete process gives rise to 22 different classes of p

204 te into biological systems, thereby changing discrete processes that influence growth, development, o

205 In this work, we leverage discrete prolate spheroidal sequences (a.k.a. Slepian se

206 tometry (BrdU incorporation) revealed that a discrete proportion of infiltrating T cells and B cells

207 confined within the domain wall, displaying discrete quantum-well energy levels.

208 e EGF receptor (Egfr) in stem cells within a discrete radius.

209 d half-site orientation, altered spacing and discrete randomization within the binding elements.

210 (Kip1), a prototypical IDP, samples multiple discrete, rapidly exchanging conformational states.

211 onships are non-spatial rather than spatial, discrete rather than continuous, and unavailable to cons

212 microscopy show that TFAM creates loops in a discrete region, the formation of which correlates with

213 e Spo11 endonuclease early in prophase I, at discrete regions in the genome coined "hot spots." In ma

214 Discrete regions of the rostral ventromedial medulla bid

215 enhancer-binding protein beta (C/EBPbeta) to discrete regulatory elements in the Wt1 locus.

216 d and further propose that the evolvement of discrete representations from continuous stimulus proper

217 We thus characterized and put into context discrete RNA structural elements, including the cis-acti

218 ries of seasonal nomadic herding could shape discrete routes of connectivity across the mountains of

219 ed that realistic complex networks emerge as discrete samples from a continuous hyperbolic geometry e

220 Broken continuous scale symmetry into discrete scale symmetry also appears for a charged and m

221 a scale-free quantum system is broken into a discrete scale symmetry for a critical value of a contro

222 There was no discrete seasonality to M. pneumoniae infections.

223 RNA ranging from single stranded regions to discrete secondary or tertiary structures.

224 whereas the lagging strand is replicated in discrete segments known as Okazaki fragments.

225 This study unravels the dynamic yet discrete self-organization of mature microglia in the he

226 ere, we show the preparation of two types of discrete, semicrystalline block co-oligomers, comprising

227 ot explained by task variables or temporally discrete sensory stimuli.

228 ive experience of sentiments, rather than on discrete sentiments themselves.

229 ynamical systems, classify inputs, and store discrete sequences that correspond to the notes of a son

230 DNA methylation changes at a discrete set of sites in the human genome are predictive

231 eeing verbs can be directed is not part of a discrete set, (2) event descriptions by users of differe

232 active arrays on the same chromosome produce discrete sets of transcripts in cis.

233 ability to harness reactive radicals through discrete, single-electron transfer (SET) events.

234 Saccharomyces cerevisiae, the complex binds discrete sites along chromosomes, including positions wi

235 otic DNA replication initiates from multiple discrete sites in the genome, termed origins of replicat

236 found that the division septum was built at discrete sites that moved around the division plane.

237 30 sub-2-nm quasispherical micelles of five discrete sizes are arranged into a tetrahedral close pac

238 By targeting the same oncogenic mutations to discrete skin compartments, we show that cell-type-speci

239 genomic loci of repressed PcG targets formed discrete, small (20-140 Kb) domains of tight interaction

240 large scale via two operationally simple and discrete solid-state processes.

241 arting from recently proposed kernels on the discrete space of protein sequences, we introduce our ow

242 molecules that leads to the amplification of discrete species.

243 Conversion success for discrete spontaneous episodes was 97.4% overall.

244 f sequence-controlled multiblock polymers in discrete stable nanoscale compartments via an emulsion p

245 ynamics during this process that reveal five discrete stages, defined in part by highly connected tra

246 Intercalation is thought to proceed in discrete stages, where each stage represents a specific

247 We developed a discrete-state stochastic framework that allowed us to i

248 It is based on a discrete-state stochastic model that takes into account

249 rmational flexibility of procaspase-6 at the discrete states that reflect the series of cleavage even

250 We validate the predicted transitions across discrete states using flow cytometry.

251 nchronize the invading virus population at a discrete step in its entry pathway will be highly valuab

252 Layer polarization evolves in discrete steps across 32 electric field-tuned phase tran

253 ct with the Bam complex, we identify several discrete steps in the assembly of a poorly characterized

254 rculation with the potential to recapitulate discrete steps of early metastatic seeding, including ar

255 arch behavior by rejecting theories based on discrete stimulus items.

256 ingle-cell RNA sequencing data together with discrete stochastic simulation, to explore the role of c

257 onsists of a series of 1 to approximately 10 discrete "sub-events" over an approximately 20 ms interv

258 rting class averages of these complexes into discrete subclasses of particles helped reduce human bia

259 ath, and the release of DNA is confined to a discrete subpolar location, which suggests a novel form

260 differentiation into PCs is induced among a discrete subset of high-affinity B cells residing within

261 CD4 T cells, and preferential depletion of a discrete subset of M. tuberculosis-specific IFN-gamma(+)

262 lamus and dorsal raphe nucleus and defined a discrete subset of transcripts expressed in these projec

263 Additionally, red pulp macrophages, a discrete subset of yolk sac-derived macrophages, were fo

264 In some cases, discrete subspecies (e.g., for Eubacterium rectale and P

265 copy showed cellular aggregates connected by discrete surface linkages.

266 sociated with devices' cycling in the mixed (discrete, switch on/off, and continuous temperature) pha

267 spatially ordered states that break various discrete symmetries, verify the high-fidelity preparatio

268 Here we report the amplification of discrete target fragments of several kilobases at 37 deg

269 erize telomere length distributions of 30-35 discrete telomeres simultaneously and accurately.

270 l rates of denitrification and anammox at 31 discrete temperatures ranging from 3 to 59 degrees C.

271 This new phase of matter has been dubbed a 'discrete time crystal'.

272 mporal changes in the association over a few discrete time frames or assumed a linear change.

273 We develop a discrete time model for population genetics of a drive a

274 was used to compare rates between groups at discrete time points.

275 Using discrete time-hazard models, we followed up families wit

276 g rates of neurons are sensitive to multiple discrete time-varying features tied to the stimulus, eac

277 Incident type 2 diabetes was assessed using discrete-time failure models, adjusting for disease risk

278 insulator-metal (MIM) capacitors that, via a discrete-time feedback loop that equalizes charging time

279 Statistical methods included discrete-time survival analyses.

280 We used discrete-time survival modelling, adjusting for town-lev

281 Here, numerical simulations with discrete tracking of red blood cells (RBCs) are performe

282 ses below threshold, clearly demonstrating a discrete transition between continence (guarding) and mi

283 stem (mES) cell differentiation, uncovering discrete transitions across nine cell states.

284 rved in a single-molecule time trajectory as discrete transitions to a state of high FRET efficiency.

285 single-nucleotide polymorphisms to identify discrete transmission chains, as well as the possible hi

286 bsorption spectroscopy provided evidence for discrete, tris-pyrazolylborate-like coordination of Co(I

287 aling behaviors that are not compatible with discrete two-state models of core complex signaling stat

288 amplitude prolonged dark current composed of discrete unitary currents similar to the Drosophila sing

289 Composed from discrete units, porous molecular materials (PMMs) posses

290 automated approach that allows generation of discrete-valued pseudo CT scans (soft tissue, bone, and

291 The discrete voids do not change the global current density

292 We found that discrete voids nucleate, grow and coalesce along the int

293 ontiers of modern electronics owing to their discrete voltage regulated operational levels.

294 ods that control transcription to initiate a discrete "wave" of elongation complexes.

295 aintenance of strain structure consisting of discrete, weakly overlapping antigenic repertoires.

296 poken languages such as German are extremely discrete, whereas others such as Portuguese are melodic

297 d spatial movement accuracy in an untrained, discrete wrist-pointing task was assessed using the same

298 tate oxidation levels to achieve a series of discrete yet fundamental fragment-coupling steps.

299 , we explore how SNARE regulators operate on discrete zippering states.

300 nd induced seismicity generally clustered in discrete zones.