ライフサイエンスコーパス: discriminate against

1 h voxels selective for the other class being discriminated against.

2 because terrestrial photosynthesis strongly discriminates against (13)CO(2), whereas ocean uptake do

3 In addition, plants discriminated against (18) O and (2) H during water upta

4 guanine for PurR and the ability of PurR to discriminate against 2-oxopurines do not result from dir

5 the substrate base that may explain how TDG discriminates against 5hmC and 5mC.

6 y deoxyribozymes show great specificity, can discriminate against a small number of mutations in the

7 While several DNA polymerases discriminated against a d(tC-A) base pair only by factor

8 ment interferes with fundamental freedoms or discriminates against a suspect class.

9 To discriminate against abundant competitors, the Nramp met

10 eady-state kinetic analysis reveals that A3A discriminates against all ox-mCs by >3700-fold, arguing

11 r results also suggest that the MAT does not discriminate against alpha-substituted acyl-CoA thioeste

12 dant interactions and enhance specificity by discriminating against alternate sites.

13 It discriminates against aminoacyl transfer RNAs that do no

14 ut how RelA recognizes stalled ribosomes and discriminates against aminoacylated tRNAs is missing.

15 signals target analytes but also stringently discriminates against analogous competing analytes.

16 ome is the fact that unattractive people are discriminated against, and that such discrimination nega

17 Also, high-pass filtering discriminated against ascorbic acid, DOPAC, and acidic p

18 th the P3 residue emerged, Kex2 was found to discriminate against at least one residue Asp. at this p

19 les mammalian 43S preinitiation complexes to discriminate against AUG codons with a context that devi

20 triplets, but it was unknown whether it also discriminates against AUGs in suboptimal context.

21 tion, and can be individually identified and discriminated against background scatter.

22 interaction of the aldehyde is critical for discriminating against BAL in some plant ALDH10s.

23 In addition to discriminating against base pair mismatches, DNA polymer

24 ting cGMP, as well as negative elements that discriminate against binding of cAMP, and that the cGMP/

25 he substitutions, A116W and N144'W, strongly discriminated against binding of GPP to the allylic site

26 Molecular modeling studies suggest how DGL discriminates against binding the biantennary complex ca

27 any state and local medical societies openly discriminated against black physicians, barring them fro

28 so demonstrate that the capacity of EF-Tu to discriminate against both of these aminoacyl-tRNAs is co

29 the target protein with a K(d) of 21 nM and discriminates against both the nonacetylated protein and

30 ctive site-binding groups in MDH effectively discriminates against both the shorter and the longer ke

31 lacking conical cells have been shown to be discriminated against by foraging bumblebees.

32 atient had been treated unfairly or had been discriminated against by health services.

33 with other rarely used initiation codons, is discriminated against by IF-3, resulting in the aborting

34 ackaging signal from phage Qbeta known to be discriminated against by MS2 coat protein both in vivo a

35 ivity mechanism that accommodates G or U but discriminates against C and A bases.

36 two sites: one site favors Mg2+ and Ba2+ and discriminates against Ca2+, while the other site favors

37 Since this waveform effectively discriminates against capacitance currents, cyclic squar

38 ome, untargeted metabolomics will inevitably discriminate against certain compound classes.

39 igators that the NIH peer review process may discriminate against clinical research.

40 evidence indicating that this conserved RNA discriminates against closely related analogues of Moco.

41 e genome are taken into account, in order to discriminate against commonly occurring patterns in the

42 ining set are taken into account in order to discriminate against commonly occurring signals and prod

43 soenergetic profiles for K(+) and Rb(+), and discriminates against Cs(+), all in agreement with exper

44 ir authentic substrates and regulators while discriminating against D-sites in other pathways.

45 That hpol eta discriminates against dATP exclusively at the insertion

46 RNA polymerases effectively discriminate against deoxyribonucleotides and specifical

47 This site discriminates against deoxyribonucleotides at the 3' end

48 ied as optimal films for PME by sufficiently discriminating against detrimental background current an

49 fer remarkable promise for cancer therapy by discriminating against devastating cytotoxicity of chemo

50 atically the ability of T7 DNA polymerase to discriminate against dideoxynucleotides.

51 cal G.C and A.T/U Watson-Crick base pairs to discriminate against DNA and RNA mismatches in order to

52 cognize the initiation codon context, and to discriminate against establishing a codon-anticodon inte

53 insights into the mechanism MutM employs to discriminate against extrahelical normal DNA bases and i

54 GGTase-I discriminates against farnesyl diphosphate (FPP) at the

55 We find that bumblebees use color cues to discriminate against flowers that lack conical cells--bu

56 e by over an order of magnitude and strongly discriminate against formation of non-native tertiary co

57 moieties of cAATrp, we demonstrate that CpaD discriminates against free Trp but accepts tryptophan-co

58 are both potent RT inhibitors, but Pol gamma discriminates against (-)-FTC-TP by two orders of magnit

59 ptors, unlike the C-X-C chemokine receptors, discriminate against Galpha16, a hematopoietic-specific

60 ting activity has evolved in this variant to discriminate against Glu.

61 petitive edge to ES, the species that better discriminated against heterospecifics.

62 However, female D. heteroneura do not discriminate against hybrids on the basis of their head

63 come revealed that the surrogate having felt discriminated against in the healthcare setting was asso

64 Remarkably, primase strongly discriminated against incorporating virtually all of the

65 t the hammerhead has an intrinsic ability to discriminate against incorrect bases, but emphasizes tha

66 er to further understand how DNA polymerases discriminate against incorrect dNTPs, we synthesized two

67 se analogues as compared to their ability to discriminate against incorrect natural dNTPs.

68 sis, DNA polymerases must rapidly sample and discriminate against incorrect nucleotides.

69 kinetics as well, which showed that T7 RNAP discriminates against incorrect NTP both at the nucleoti

70 Instead, hPolbeta discriminates against L-stereochemistry through accumula

71 e.g. 4-phenylimidazole and morpholine) while discriminating against larger azole drugs.

72 binding pocket selective for fluoride, while discriminating against larger halide ions.

73 learn to recognize their own chicks and then discriminate against later-hatched parasitic chicks in t

74 bias during the PCR amplification step that discriminates against longer homologs, as we show experi

75 L variant, supporting a model in which IFE-3 discriminates against m(3)(2,2,7)GTP by steric hindrance

76 Island females strongly discriminated against mainland males, suggesting that di

77 ften favor members of their own group, while discriminating against members of other groups.

78 ants the nanogap sensor excellent ability to discriminate against mismatched sequences and allows hyb

79 rong, and the ability of each to effectively discriminate against mismatches in short duplex DNA.

80 step of strand exchange, the enzyme strongly discriminates against mismatches close to the cleavage s

81 t, whereas the Klenow fragment more strongly discriminates against mismatches, in accord with its gre

82 igid drug binding pocket that can be used to discriminate against molecules that are not substrates o

83 4me3- over K4me2-containing H3 peptides, and discriminates against monomethylated and unmodified coun

84 nsing Watson-Crick base-pairing geometry and discriminating against near-cognate tRNA.

85 bute to the fidelity of protein synthesis by discriminating against near-cognate tRNAs on the ribosom

86 ct the integrity of the tRNA molecule and to discriminate against nicked or damaged species from furt

87 d that eliminates sample to sample variance, discriminates against noise and artifacts, and improves

88 ent to bind all GU-rich sequences and yet to discriminate against non-GU-rich RNAs.

89 NA folding is that the free-energy landscape discriminate against non-native folds.

90 e site contacts that play essential roles in discriminating against non-substrates in the wild-type e

91 icity of the "native" protein-ligand complex discriminating against "non-native" binding modes and th

92 nslation, aminoacyl-tRNA synthetases (AARSs) discriminate against noncognate amino acids and cellular

93 ination, explaining the ability of LysRS1 to discriminate against noncognate substrates accepted by L

94 ficity toward the l-enantiomer of lysine and discriminated against noncognate amino acids with differ

95 NA synthetase (GlnRS) reveal that the enzyme discriminates against noncognate glutamate at multiple s

96 When amoebae aggregate they do not perfectly discriminate against nonkin, leading to chimeric fruitin

97 rahymena ribozyme to optimize its ability to discriminate against nonspecific substrates in vitro.

98 We have investigated how AAG discriminates against normal DNA bases, while accommodat

99 til (silk and ovary) a number of maize genes discriminate against or exclude pollen not carrying the

100 than the trimer and slightly less ability to discriminate against other DNA sequences.

101 ement to bind many GU-rich sequences and yet discriminate against other RNAs.

102 th an affinity of approximately 5 microM and discriminates against other sequences lacking the centra

103 V-associated pneumonia, although its role in discriminating against other respiratory viral-associate

104 mL depending on assay format) while strongly discriminating against other VLP types.

105 ts that, in fact, group-biased behavior that discriminates against out-groups is not inevitable after

106 how the aptamer specifically selects p50 and discriminates against p65.

107 This indicates that F227A discriminates against particular base substitutions.

108 eld study, egg-laying E. solidaginis females discriminated against plants previously exposed to the s

109 Pol alpha strongly discriminated against polymerizing dATP opposite 8-oxoG,

110 Although eIF1 autoregulates by discriminating against poor context in yeast and mammals

111 rm competition and female choice of sperm by discriminating against previous mates.

112 ggested to alter ribosomal fine structure to discriminate against prolyl-tRNA(Pro) and promote termin

113 Ps) contributes to C/EBPalpha specificity by discriminating against purines at position -3 and imposi

114 Nase T displays an unusual base specificity, discriminating against pyrimidine and, particularly, C r

115 Although most DNA polymerases discriminate against ribonucleotide triphosphaets (rNTPs

116 While most DNA polymerases discriminate against ribonucleotide triphosphate (rNTP)

117 approximately 1,000-fold-reduced ability to discriminate against ribonucleotides compared to that of

118 ratios, by the ability of DNA polymerases to discriminate against ribonucleotides, and by the capacit

119 Although DNA polymerases discriminate against ribonucleotides, many therapeutic n

120 da used a novel sugar selection mechanism to discriminate against ribonucleotides, whereby the ribose

121 dependent insertion represents a key step in discriminating against ribonucleotides because, once ins

122 subunits (R(CE)) of PKAI(CE) and stringently discriminates against RIIalpha and RIIbeta subunits, the

123 us of the AKAP helix, the hydrophobic groove discriminates against RIIalpha.

124 r lambda cro RNA but a much lower ability to discriminate against RNA molecules lacking cis-acting Rh

125 At amino acid 62, Phe discriminates against RNA binding and Tyr allows RNA bin

126 a monomer in a sequence-specific manner, and discriminates against RNA of telomeric sequence.

127 plays a high level of substrate specificity, discriminating against RNAs that contain a single base m

128 nsure genome stability, DNA polymerases must discriminate against rNTPs and incorporated ribonucleoti

129 sensitivities to ddNTPs and their ability to discriminate against rNTPs versus dNTP substrates on nat

130 s from several distinct families selectively discriminate against rUTP.

131 says, and confirmed that these RNAs strongly discriminate against SAM and other closely related analo

132 ing domain, utilizes pre-transfer editing to discriminate against serine.

133 ive analysis of gene expression and does not discriminate against short or structured RNAs.

134 ides after 3-nitrotyrosine while effectively discriminating against similar peptides containing unmod

135 The enzyme must, however, also discriminate against smaller substrates, such as pyruvat

136 ersally detect any organic compound, it will discriminate against species with high molar absorptivit

137 s a litmus test for these FMS hallmarks that discriminates against spurious contributions from magnet

138 However, current methods frequently discriminate against structured and/or small RNA species

139 ic Tev-LHEs are active in vivo and similarly discriminate against substrates lacking the 5'-CNNNG-3'

140 transcriptase (RT) that allow the enzyme to discriminate against such analogs.

141 rties in the ability of CaM to recognize and discriminate against targets by tuning its conformationa

142 a lesion-bypass DNA polymerase) specifically discriminates against tC in the template strand may sugg

143 pair only by factors <10, T7 RNA polymerase discriminates against tC-A base pair formation by factor

144 in the template strand may suggest that DinB discriminates against template modifications in the majo

145 of aromatic residues, which is predicted to discriminate against the CoA thioesters.

146 may be common in the ocean but difficult to discriminate against the complex chemical background of

147 ucker and trans peptide bond, P4H appears to discriminate against the conformation of proline residue

148 isplays asymmetry in terms of its ability to discriminate against the modification of the DNA templat

149 tics strongly suggests that SepRS is able to discriminate against the noncognate amino acids glutamat

150 Both mutants and the wild-type enzyme discriminated against the mismatched primer at the catal

151 PBP2a effectively discriminates against the beta-lactam antibiotics as pot

152 at the electrode surface while cytochrome c discriminates against the electrode surface.

153 Also, RedJ strongly discriminates against the streptomycete ACP of fatty aci

154 with the dithiolane ring of lipoic acid and discriminating against the entry of biotin.

155 heterologous systems in a reciprocal manner, discriminating against the formation of initiation compl

156 beta-Glu(44) with alanine prevented IHF from discriminating against the H'44A variant but not the oth

157 join correctly base-paired substrates, while discriminating against the ligation of substrates contai

158 s for reading the isoleucine codon AUA while discriminating against the methionine codon AUG.

159 zyme plays an important role in catalysis by discriminating against the monoanionic form of substrate

160 osphorylation of Thr-38 while simultaneously discriminating against the phosphorylation of Ser-26 is

161 e Asp133 of dCK that is most responsible for discriminating against the thymine base.

162 ng reference chicks, coots can be induced to discriminate against their own offspring, confirming tha

163 w fragment exhibit a remarkable inability to discriminate against these analogues as compared to thei

164 Both EF-Tu orthologs discriminate against these misacylated tRNAs, confirming

165 By discriminating against these misacylated tRNAS, EF-Tu pl

166 n products suggests that the polymerases may discriminate against this pairing system on the basis of

167 However, Cre discriminates against this substrate both before and aft

168 pairing specificity, we have hypothesized to discriminate against U/G wobble pair by tailoring the st

169 nine (oxoG) to be correctly paired, while it discriminates against U-oxoG and G-oxoG mispairs.

170 identical to the native U/A base pair, while discriminating against U/G wobble pair.

171 nability of pol alpha and Klenow fragment to discriminate against unnatural bases.

172 ns greatly complement direct interactions in discriminating against various types of trap interaction

173 dy of work has shown that insect pollinators discriminate against white phenotypes when white flowers