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1 used by PCV7 serotypes, 0.17 (0.07-0.42) for disease caused by 1, 5, and 7F serotypes, and 0.41 (0.25
2 ogy of schistosomiasis, a neglected tropical disease caused by a chronic infection with parasitic hel
5 se) is a neurodegenerative lysosomal storage disease caused by a deficiency in palmitoyl protein thio
6 circuit are fundamentally altered in a brain disease caused by a known molecular defect and that fixi
7 keletal components play in the growth of and disease caused by a known pathogen, prompting future stu
9 ntington disease (HD) is a neurodegenerative disease caused by a mutation in the huntingtin (HTT) gen
10 a progressive, adult-onset neurodegenerative disease caused by a polyglutamine (polyQ) expansion in t
11 n autosomal dominant fatal neurodegenerative disease caused by a polyglutamine expansion in the codin
12 sease (HD) is an inherited neurodegenerative disease caused by a polyglutamine expansion in the hunti
13 and severe human degenerative nervous system disease caused by a primary astroglial abnormality, to p
14 etanus is a life-threatening but preventable disease caused by a toxin produced by Clostridium tetani
15 neuronal ceroid lipofuscinosis (NCL, Batten disease) caused by a mutation in CLN5 In humans, mutatio
16 on's disease (HD) is a polyglutamine (polyQ) disease caused by aberrant expansion of the polyQ tract
17 e is an autosomal dominant neurodegenerative disease caused by abnormal polyglutamine expansion in hu
18 e 1 (DM1) and type 2 (DM2) are neuromuscular diseases, caused by accumulation of CUG and CCUG RNAs in
19 yndrome (APDS) is a primary immunodeficiency disease caused by activating mutations in either the leu
22 TION: The incidence of invasive pneumococcal disease caused by all serotypes decreased due to a decli
23 ed transcriptomics based diagnosis tools for diseases caused by altered gene expression, or used for
24 ington's disease (HD) is a neurodegenerative disease caused by an abnormal expansion in the polygluta
26 nic wasting disease is a fatal, neurological disease caused by an infectious prion protein, which aff
28 strophy (DMD) is a progressive neuromuscular disease, caused by an absence of dystrophin, inevitably
29 al importance within the context of neuronal diseases caused by an impaired glyoxalase system and ele
30 gical processes, including tumorigenesis and diseases caused by an overly aggressive immune response.
33 zing antibodies can mitigate the severity of disease caused by arenaviruses, particularly species fou
36 n recognized so far as features of the liver disease caused by ATZ and are likely involved in metabol
38 en disease, is a pediatric lysosomal storage disease caused by autosomal recessive mutations in CLN3,
39 thy (GAN) is a progressive neurodegenerative disease caused by autosomal recessive mutations in the G
40 scinosis (JNCL) is a fatal lysosomal storage disease caused by autosomal-recessive mutations in CLN3
41 r risk factor for melioidosis, an infectious disease caused by B. pseudomallei, is diabetes mellitus.
43 Human babesiosis is a tick-borne multisystem disease caused by Babesia species of the apicomplexan ph
45 NE myopathy is an autosomal recessive muscle disease caused by biallelic mutations in GNE, a gene enc
46 highlighted in a patient with mitochondrial disease caused by biallelic pathogenic variants in TOP3A
50 iagnostics, and vaccine candidates to combat diseases caused by Bp and Bm.Melioidosis and glanders ar
53 ) is an autosomal dominant neurodegenerative disease caused by CAG repeat expansion in the ATXN2 gene
54 healthy patients with other forms of severe disease caused by Candida, Trichophyton, Phialophora, an
55 therwise healthy patients with severe fungal diseases caused by Candida species, dermatophytes, or Ph
56 e responses of maize to grey leaf spot (GLS) disease caused by Cercospora zeina, a threat to maize pr
58 /PTX3 is a novel approach to prevent dry eye disease caused by cGVHD and allow us to test its safety
59 lepsy has traditionally been thought of as a disease caused by changes in neuronal properties exclusi
60 Since koalas frequently suffer from ocular diseases caused by Chlamydia infection, we also examined
61 Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive sec
65 d progeria syndrome (HGPS) is a rare genetic disease caused by defective prelamin A processing, leadi
66 is a devastating inherited neurodegenerative disease caused by defects in the ABCD1 gene and affectin
67 overy adds to the emerging spectrum of human diseases caused by defects in the ubiquitin pathway and
68 nemia type 1 (HT1) is an autosomal recessive disease caused by deficiency in fumarylacetoacetate hydr
69 bry disease is an X-linked lysosomal storage disease caused by deficient activity of alpha-galactosid
70 vine footrot is a highly prevalent bacterial disease caused by Dichelobacter nodosus and characterise
72 platform for PoC serodiagnosis of infectious diseases caused by different types of microorganisms (pa
74 rvival and iron deficiency; and mineral bone disease caused by disturbed vitamin D, calcium, and phos
76 99 % were aware that diabetes was a blinding disease caused by DR.11.5 % of the subjects were aware o
81 lthough there is no evidence for symptomatic disease caused by either Marburg or Ebola viruses in bat
82 acteristics, and management of patients with disease caused by Emmonsia sp., a novel dimorphic fungal
83 pt that this technology can be used to treat disease caused by epigenetic silencing of specific loci.
85 Huntington's disease (HD) is a rare genetic disease caused by expanded polyglutamine repeats in the
86 7 (SCA7) is a debilitating neurodegenerative disease caused by expansion of a polyglutamine [poly(Q)]
88 's disease (HD) is a fatal neurodegenerative disease, caused by expansion of polyglutamine repeats in
96 autosomal dominant combined immunodeficiency disease caused by gain-of-function mutation of the chemo
97 Long QT syndrome type 3 (LQT3) is a lethal disease caused by gain-of-function mutations in the SCN5
98 an 300 million people suffer from a range of diseases caused by gastropod-borne helminths, predominan
101 diagnosis and surveillance of infection and disease caused by H. haemolyticus and NT H. influenzae.
104 tational knock-in at single alleles to model diseases caused by heterozygous mutations has not been r
106 peutic approaches to prevent and treat human disease caused by highly pathogenic avian influenza viru
107 ataxia (FRDA) is a severe neurodegenerative disease caused by homozygous expansion of the guanine-ad
108 inal disease irrespective of HPV type (i.e., disease caused by HPV types included in the 9vHPV vaccin
109 high efficacy against incident infection and disease caused by HPV types that they specifically targe
112 , the pegiviruses, are thought to reduce the disease caused by human immunodeficiency virus (HIV) in
113 n diseases, including delayed progression of disease caused by human immunodeficiency virus type 1 (H
114 Psoriasis vulgaris is an inflammatory skin disease caused by hyperactivated T cells regulated by po
115 ge numbers of patients with end-stage kidney disease caused by IgA nephropathy are transplanted every
116 (LC) amyloidosis (AL) is a potentially fatal disease caused by immunoglobulin LC produced by clonal p
117 strophy (APECED), a T cell-driven autoimmune disease caused by impaired central tolerance, are suscep
118 -linked hypophosphatemia (XLH) is a skeletal disease caused by inactivating mutations in the PHEX gen
120 Schistosomiasis is a debilitating tropical disease caused by infection with parasitic blood flukes.
122 for periodontitis as a chronic inflammatory disease caused by infectious agents in RA seems biologic
123 Tuberculosis (TB) is a significant human disease caused by inhalation of Mycobacterium tuberculos
124 reich's ataxia (FRDA) is a neurodegenerative disease caused by inherited deficiency of the mitochondr
125 Background Babesiosis, a tickborne zoonotic disease caused by intraerythrocytic protozoa of the genu
126 halitis is an acute zoonotic, mosquito-borne disease caused by Japanese encephalitis virus (JEV).
127 been vital for controlling the incidence of disease caused by JEV, particularly in rural areas of As
128 PEL) are two well-known inflammation related diseases caused by Kaposi's sarcoma-associated herpesvir
129 Leishmaniasis is a highly diverse group of diseases caused by kinetoplastid of the genus Leishmania
132 on between a decrease of pericytes and liver disease caused by ligature-induced periodontitis in rats
133 igate the heterogeneity in manifestations of disease caused by Listeria monocytogenes and demonstrate
134 uscular atrophy (SMA) is a neurodegenerative disease caused by loss of motor neurons in patients with
136 pinal muscular atrophy (SMA) is a motoneuron disease caused by loss or mutation in Survival of Motor
138 se model for Keutel syndrome, a rare genetic disease caused by loss-of-function mutations in the matr
139 al muscular atrophy (SMA) is a neuromuscular disease caused by low levels of SMN protein, primarily a
140 esent an overview of the diffuse cystic lung diseases caused by lymphoproliferative disorders, geneti
143 lly, new research, such as studies of severe diseases caused by miRNA malfunction, will benefit from
146 athies are a group of phenotypically related diseases caused by monogenic mutations that primarily af
148 lor FluoroSpot assay can be applied to other diseases caused by multiple pathogen serotypes in which
149 dermia and cardiomyopathy to the spectrum of disease caused by mutation in DSP, and identify a specif
150 e type 1b (GSD-1b) is an autosomal-recessive disease caused by mutation of glucose-6-phosphate transp
153 as giant axonal neuropathy (GAN), a ravaging disease caused by mutations in GAN, encoding gigaxonin.
154 y considered to be a genetically homogeneous disease caused by mutations in PKHD1, has been associate
155 al muscular atrophy (SMA) is a neuromuscular disease caused by mutations in Survival Motor Neuron 1 (
158 stic fibrosis (CF) is a major lethal genetic disease caused by mutations in the CF transmembrane cond
159 Cystic fibrosis is an autosomal recessive disease caused by mutations in the CFTR gene that lead t
160 rmolysis bullosa is a devastating blistering disease caused by mutations in the COL7A1 gene, which en
161 ataxia type 5 (SCA5) is a neurodegenerative disease caused by mutations in the cytoskeletal protein
162 ) is a severe and progressive muscle-wasting disease caused by mutations in the dystrophin gene.
163 DMD) is an incurable X-linked muscle-wasting disease caused by mutations in the dystrophin gene.
164 Giant axonal neuropathy (GAN) is a rare disease caused by mutations in the GAN gene, which encod
165 lar dystrophy (DMD) is an X-linked recessive disease caused by mutations in the gene encoding dystrop
166 phenocopying what has been reported for Dent disease caused by mutations in the gene encoding endosom
167 ephalomyopathy (MNGIE) is a fatal, recessive disease caused by mutations in the gene encoding thymidi
168 epidermolysis bullosa (RDEB) is an incurable disease caused by mutations in the gene encoding type VI
169 syndrome is a rare but devastating childhood disease caused by mutations in the IDS gene encoding idu
170 -C) is a progressive lysosomal lipid storage disease caused by mutations in the NPC1 and NPC2 genes.
171 of premature aging.HGPS is a premature aging disease caused by mutations in the nuclear protein lamin
172 a rare autosomal-dominant neurodegenerative disease caused by mutations in the TGM6 gene, which code
173 DYT1) is a dominantly inherited neurological disease caused by mutations in TOR1A, the gene encoding
174 F) is an IL-1beta-dependent autoinflammatory disease caused by mutations of Mediterranean fever (MEFV
175 Cystic fibrosis (CF) is a common genetic disease caused by mutations of the cystic fibrosis trans
176 Cystic fibrosis (CF) is a lethal genetic disease caused by mutations of the gene encoding the cys
177 taxia type 28 (SCA28) is a neurodegenerative disease caused by mutations of the mitochondrial proteas
178 ulation is particularly valuable in cases of disease caused by mutations that lead to disruption of n
179 uronal ceroid lipofuscinosis (JNCL or Batten disease) caused by mutations in the CLN3 gene is the mos
180 thies (NMs) are a group of congenital muscle diseases caused by mutations in at least 10 genes and as
181 asma factor H (FH) as exemplified by various diseases caused by mutations in its domains 19-20 (FH19-
182 tronuclear myopathies are early-onset muscle diseases caused by mutations in several genes including
184 ncy and toxicity disorders Menkes and Wilson diseases caused by mutations in the p-type Cu-ATPase gen
185 stem to establish a mechanistic link between diseases caused by mutations in two distinct genes, hnRN
186 r adhesion, and informs our understanding of diseases caused by mutations in USH1C and ankyrin repeat
190 ts for tuberculosis (TB), a major infectious disease caused by Mycobacterium tuberculosis (Mtb), whic
191 accinees, although no cases of meningococcal disease caused by N. meningitidis B were reported among
192 s, we present an overview of the cystic lung diseases caused by neoplasms, infections, smoking-relate
193 By contrast, that of invasive pneumococcal disease caused by non-PCV13 serotypes increased, which s
194 The pooled IRR for invasive pneumococcal disease caused by non-PCV13 serotypes was 1.62 (1.09-2.4
196 a genetic paradigm of cerebral small vessel disease caused by NOTCH3 mutations that stereotypically
197 therapeutic and preventative strategies for diseases caused by NTHI and many other human pathogens k
198 phy type 1 (DM1) is a dominant neuromuscular disease caused by nuclear-retained RNAs containing expan
199 specially in age-dependent neurodegenerative diseases caused by nucleotide repeat expansion, have hig
201 gical response of the organism to infectious diseases caused by organisms such as bacteria, viruses,
204 Graves' hyperthyroidism, a common autoimmune disease caused by pathogenic autoantibodies to the thyro
207 caused by any serotype, 0.16 (0.07-0.40) for disease caused by PCV7 serotypes, 0.17 (0.07-0.42) for d
208 d help to design better treatments for human diseases caused by perturbations in fluid osmolarity.
210 ington's Disease (HD) is a neurodegenerative disease caused by poly-glutamine expansion in the Htt pr
211 al muscular dystrophy (OPMD) is a late onset disease caused by polyalanine expansion in the poly(A) b
212 trophy (SBMA) is a progressive neuromuscular disease caused by polyglutamine expansion in the androge
214 gests that the likelihood of having reported disease caused by PRN(-) compared with PRN(+) strains is
215 on diseases represent the archetype of brain diseases caused by protein misfolding, the most common s
216 on diseases represent the archetype of brain diseases caused by protein misfolding, with the most com
220 patients (>/=18 years) with invasive fungal disease caused by rare fungi, including mucormycosis, we
221 tifocal leukoencephalopathy (PML) is a fatal disease caused by reactivation of JC polyomavirus (JCPyV
223 al muscular atrophy (SMA) is a neuromuscular disease caused by reduced expression of survival of moto
228 e are large data gaps in the epidemiology of diseases caused by Salmonella enterica in West Africa.
229 , an important biocontrol agent against crop diseases caused by Sclerotinia sclerotiorum, was identif
234 y can be a promising method to treat genetic diseases caused by splicing errors, but the efficiency o
235 associated with human disease, the burden of disease caused by STEC strains that lacks LEE (LEE-negat
237 annually by preventing invasive pneumococcal disease caused by Streptococcus pneumoniae Some componen
239 Botulism is a potentially fatal paralytic disease caused by the action of botulinum neurotoxin (Bo
240 ges in either group in invasive pneumococcal disease caused by the additional 11 serotypes covered by
242 Colorectal cancer (CRC) is a common complex disease caused by the combination of genetic variants an
243 Classic galactosemia is a potentially lethal disease caused by the dysfunction of galactose 1-phospha
244 is a dominantly inherited neurodegenerative disease caused by the expansion of a CAG repeat in the H
245 nic dystrophy Type 1 (DM1) is a rare genetic disease caused by the expansion of CTG trinucleotide rep
246 dystrophy type 2 is a genetic neuromuscular disease caused by the expression of expanded CCUG repeat
247 ntington's disease (HD), a neurodegenerative disease caused by the expression of mutant huntingtin pr
248 chocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvu
249 s) likely contributes to the pathogenesis of disease caused by the filoviruses Ebola virus and Marbur
250 pergillosis (IPA) is a life-threatening lung disease caused by the fungus Aspergillus fumigatus, and
253 alopathy (PML) is a lethal CNS demyelinating disease caused by the human neurotropic polyomavirus JC
254 nic hyperproliferative and inflammatory skin disease caused by the interplay of genetic and environme
255 kinson's disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons in th
256 lateral sclerosis (ALS), a neurodegenerative disease caused by the loss of motor neurons leading to p
257 fever, an acute and often chronic arthralgic disease caused by the mosquito-borne chikungunya virus (
258 sease (HD) is an inherited neurodegenerative disease caused by the mutant huntingtin gene (mHTT), whi
260 r the treatment of toxoplasmosis, which is a disease caused by the protozoan parasite Toxoplasma gond
261 ing mosquito-borne zoonotic infectious viral disease caused by the RVF virus (RVFV) (Bunyaviridae: Ph
262 chinson-Gilford progeria syndrome, a genetic disease caused by the synthesis of an internally truncat
263 ive up regulated resistant genes Coffee rust disease, caused by the fungus Hemileia vastatrix, is one
264 pe to treatment using the newly defined XMEN disease, caused by the genetic loss of the MAGT1 magnesi
269 , lupus nephritis and other autoinflammatory diseases caused by the decreased ability of ABIN1 or oth
270 hatic filariasis and loiasis are major human diseases caused by the insect-borne filarial nematodes B
271 information to discover the genetic basis of diseases caused by the mis-regulation of gene expression
273 lth problems worldwide, and the incidence of diseases caused by the virus has increased dramatically.
275 he high mortality (>60%) associated with the disease caused by these viruses and the lack of protecti
280 nce: Infantile beriberi, a potentially fatal disease caused by thiamine deficiency, remains a public
281 proaches are necessary for the prevention of disease caused by this canine respiratory pathogen.
282 proaches are necessary for the prevention of disease caused by this important human respiratory patho
283 to develop more effective vaccines to combat disease caused by this important respiratory pathogen.
286 hodesian sleeping sickness, a fatal zoonotic disease caused by trypanosomes transmitted by tsetse fli
288 sical osteogenesis imperfecta (OI) is a bone disease caused by type I collagen mutations and characte
290 nse and its potential participation in human diseases caused by unfolded protein response.IRE1alpha i
292 cribe the genotype-phenotype correlations of diseases caused by variants in Fibroblast Growth Factor
293 erstanding of genetic disease in general and diseases caused by variation in FGFR1 specifically.
298 sistant to most devastating bacterial blight diseases caused by Xanthomonas oryzae pv. oryzae (Xoo).
299 ic plague represents the most severe form of disease caused by Yersinia pestis due to its ease of tra
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