ライフサイエンスコーパス: disease is

1 ost-operative chylothorax in patients with congenital heart disease is a challenging problem with substantial morbidity a

2 Inherited retinal disease is a common cause of visual impairment and represents

3 BACKGROUND & AIMS: Wilson disease is a disorder of copper (Cu) misbalance caused by mut

4 Stargardt disease is a juvenile onset retinal degeneration, associated

5 Cardiovascular disease is a leading cause of death among incarcerated indivi

6 Liver disease is a major cause of non-AIDS-related deaths, and as a

7 Treatment for end-stage kidney disease is a major economic challenge and a public health con

8 xtent to which non-coding mutations contribute to Mendelian disease is a major unknown in human genetics.

9 In conclusion, pulmonary NTM disease is a neglected and emerging public health disease and

10 The Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder due

11 The disease is a potential target for stem cell therapy but succe

12 Some evidence suggests that chronic kidney disease is a risk factor for lower-extremity peripheral arter

13 Hepatitis C virus (HCV)-mediated chronic liver disease is a serious health problem around the world and ofte

14 ng process of ACS patients with obstructive coronary artery disease is associated with a high reclassification rate of tr

15 Huntington's disease is caused by a CAG repeat expansion in the huntingtin

16 In most cases, the disease is caused by mutations in OPA1, a gene encoding a mit

17 The disease is characterized by destruction of the alveolar bone

18 BACKGROUND & AIMS: Celiac disease is characterized by HLA-DQ2/8-restricted responses of

19 Diverticular disease is characterized by pouches (that is, diverticulae) d

20 mong whom cardiovascular disease risk is elevated and liver disease is common.

21 bowel disease unclassified before the age of 10 years, the disease is complex, multifactorial, and lifelong, and affects

22 Peripheral artery disease is considered to be a manifestation of systemic ather

23 e brain tissue of HIV patients without serious neurological disease is consistent with their emergence from a viral popul

24 Serum specimens from 170 controls from areas in which the disease is endemic and 44 cases were tested by immunodiffusio

25 a who have immigrated from or travelled to areas where this disease is endemic.

26 easure to predict progression to death after coronary heart disease is established.

27 Unlike CAH caused by 21-hydroxylase deficiency, the disease is far more common in the Middle East and North Afric

28 disease event types to the excess burden of cardiovascular disease is important for developing effective strategies to i

29 The impact of the microbiota in health and disease is in part a function of the nutrient processing and

30 variation underlying many heritable forms of cardiovascular disease is incompletely understood, even in patients with str

31 The most common pediatric mitochondrial disease is Leigh syndrome, an episodic, subacute neurodegener

32 The major risk factor for neonatal disease is maternal vaginal colonization.

33 largely assumed that the contribution of fungi to allergic disease is mediated through their potent antigenicity.

34 Huntington's disease is neurodegenerative disorder caused by a polyglutami

35 c muscle function; however, the connection between FXR1 and disease is not clear.

36 al using traditional computed tomography criteria have mild disease is not known.

37 Atherothrombotic vascular disease is often triggered by a distinct type of atherosclero

38 Nonalcoholic fatty liver disease is one of the most prevalent metabolic disorders and

39 The mortality among persons with Parkinson disease is only moderately increased compared with the genera

40 known for more than 60 years that the cause of sickle cell disease is polymerization of a hemoglobin mutant, hydroxyurea

41 The pathophysiology of carcinoid heart disease is poorly understood; however, chronic exposure to ex

42 specific cardiovascular differences both at baseline and in disease is required to effectively consider and treat all pat

43 One of the main research topics related to Alzheimer's disease is the aggregation of the amyloid-beta peptide, which

44 Congenital heart disease is the most common birth defect, and because of major

45 Increased pulmonary venous pressure secondary to left heart disease is the most common cause of pulmonary hypertension (P

46 Although the root cause of sickle cell disease is the polymerization of hemoglobin S (HbS) to form f

47 cts may be used to distinguish genes whose association with disease is through promotion versus protection, thereby linki

48 The mechanism(s) by which mutant HTT (mHTT) causes disease is unclear.

49 ately 10% of affected individuals, the genetic cause of the disease is unknown, suggesting that other loci are most likel

50 ed of the islet amyloid polypeptide (IAPP), its role in the disease is unknown.