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1                                       Progression of kidney disease was defined as a doubling of baseline serum creatinin
2                                              Chronic kidney disease was defined as a glomerular filtration rate less than
3                                              Cardiovascular disease was defined as a history of angina, myocardial infarc
4                                                     Cardiac disease was defined as a history of atrial fibrillation, isch
5 cording to standard clinical criteria, while cardiovascular disease was defined as a history of heart attack or heart sur
6                             Gluten avoidance without celiac disease was defined as adherence to a gluten-free diet withou
7                                         Peripheral arterial disease was defined as an ankle brachial index <0.9 in at lea
8                                         Peripheral arterial disease was defined as an ankle-brachial blood pressure index
9                                    Lower extremity arterial disease was defined as an ankle/arm systolic blood pressure r
10                                              Chronic kidney disease was defined as an estimated GFR of less than 60 mL/mi
11                                              Chronic kidney disease was defined as an estimated glomerular filtration rat
12                                      Active coronary artery disease was defined as any elevated serum enzyme levels, coro
13                                                      Active disease was defined as ASDAS >/= 2.1.
14                                        Extracranial carotid disease was defined as cervical internal carotid artery steno
15                                                 Unfavorable disease was defined as clinical stage I and II with bulky per
16                                              Chronic kidney disease was defined as confirmed (>3 months apart) eGFR lower
17                                              Chronic kidney disease was defined as creatinine clearance <60 mL/min.
18                              Moderate-to-severe periodontal disease was defined as cumulative numbers of teeth exhibiting
19                                                    Incident disease was defined as development of OA defined as a modifie
20                                             Diabetic kidney disease was defined as diabetes with albuminuria (ratio of ur
21                                             End-stage renal disease was defined as dialysis attributed to diabetic nephro
22                                              Chronic kidney disease was defined as eGFR<60 mL/min per 1.73 m2.
23                                              Chronic kidney disease was defined as estimated glomerular filtration rate l
24                                               Major chronic disease was defined as fatal or nonfatal cardiovascular disea
25                                              Coronary heart disease was defined as fatal or nonfatal myocardial infarctio
26                                             Coronary artery disease was defined as &gt; or =70% stenosis of > or =1 coronary
27                                                    Advanced disease was defined as hepatic insufficiency leading to OLT w
28                                                   Malignant disease was defined as high-grade dysplasia or invasive adeno
29                                                CMV GI tract disease was defined as histopathologic evidence of CMV on bio
30                                              Valvular heart disease was defined as history or baseline echocardiography e
31        A probable case of laboratory-acquired meningococcal disease was defined as illness meeting the case definition fo
32 ed airway disease as juveniles, in which exacerbated airway disease was defined as increased cellular infiltration into t
33                                                SLN-positive disease was defined as individual tumor cells or cell aggrega
34                         Severe angiographic coronary artery disease was defined as left main disease, three-vessel diseas
35                                       Advanced histological disease was defined as Ludwig stages 3 or 4.
36                                              Chronic kidney disease was defined as moderate-to-severe reduction of kidney
37                                    Non-fatal cardiovascular disease was defined as non-fatal coronary heart disease or no
38                                          Platinum-resistant disease was defined as progression on platinum-based chemothe
39                 Clinical response for patients with luminal disease was defined as reduction in CDAI score of >150 points
40 underwent invasive coronary angiography and coronary artery disease was defined as stenosis >/=50% luminal diameter (quan
41                                                Incident PAC disease was defined as the development of PAC disease during
42                                               Major chronic disease was defined as the initial occurrence of cardiovascul
43                                                    Incident disease was defined as the occurrence of new radiographic OA
44                                  Progression of periodontal disease was defined as the percentage of teeth per decade tha
45                                   The duration of untreated disease was defined as the period of time from the onset of r
46                                          Active periodontal disease was defined as the presence of moderate/severe period
47                                                 Periodontal disease was defined as two or more teeth with clinical attach
48                                                   Gallstone disease was defined as ultrasound-documented gallstones or ev
49                            Gallstone-associated gallbladder disease was defined as ultrasound-documented gallstones or ev
50                                                 Gallbladder disease was defined as ultrasound-documented gallstones or ev

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