ライフサイエンスコーパス: disengage

1 mitosis or early G1 phase, when they become disengaged.

2 were less clearly defined when tracking was disengaged.

3 TJ- and AJ-integral membrane proteins can be disengaged.

4 nd leaves NF155 on apposing paranodal myelin disengaged.

5 ndodomain is truncated and cAMP induction is disengaged.

6 for transport (ESCRT) machinery is purposely disengaged.

7 during 2013-2014 and outcomes for those who disengaged.

8 lassical ERalpha signaling is epigenetically disengaged.

9 :UAF1 deubiquitinase only occurs when DNA is disengaged.

10 sic endonuclease activity, which removes the disengaged 3' RNA segment.

11 clinical trials, or HER4 antagonists, which disengage 4ICD signaling, may have untoward activity in

12 tor output decays because the brain actively disengages a component of the memory.

13 hat SSeCKS suppresses metastatic motility by disengaging activated Src and then inhibiting the PKC-Ra

14 ells usually do not fuse with each other but disengage after the viral particles have been delivered,

15 a targets a specific SAP97 splice variant to disengage AKAP79/150 from regulating GluR1 AMPARs, provi

16 mers when they are not bound to DNA and then disengage and are replaced by class II ERPs to form high

17 opose a model in which flagellar stators are disengaged and sequestered from the flagellar rotor when

18 during preprotein import, the Toc159G dimer disengages and the dimer interface contacts translocatin

19 ovince clinic within 180 days, 9,005 (22.6%) disengaged, and 28,069 (70.4%) remained in care.

20 and in the absence of nucleotides, the NBDs disengage asymmetrically while the conformation of the T

21 hemineglect, and specifically difficulty in disengaging attention in tests of covert orienting.

22 This mechanism to disengage bacterial clearance from inflammation required

23 alone (imatinib) is not sufficient to fully disengage BCR-ABL-mediated signaling and suggests that B

24 rs Axin's affinity for beta-catenin, thereby disengaging beta-catenin from the degradation machinery.

25 CA1 pyramidal neurons that can be engaged or disengaged by small shifts in net membrane current near

26 going some type of cytoplasmic processing to disengage c27/25 mRNA and make it available for translat

27 arch by remodeling the splicing substrate to disengage candidate splice sites.

28 While most cells with disengaged centrioles maintain spindle bipolarity, clust

29 s maintain spindle bipolarity, clustering of disengaged centrioles requires the kinesin-14, HSET.

30 nt on Cdk2/cyclin E, and requires previously disengaged centrioles.

31 ing meiosis II, resulting in spermatids with disengaged centrioles.

32 all impact in the 1- to 13-J range, 10 (17%) disengaged completely from the orbital mount.

33 ies down the key catalytic dynamic loop in a disengaged conformation and also locks the tetramer in a

34 e AMP complex) with active site loops in the disengaged conformation.

35 E(2) recruited ERalpha and disengaged corepressors from DACH1 at an endogenous ER r

36 Disengaged countertransference was associated with schiz

37 -risk group, which manifests as a failure to disengage default-mode regions in those at familial risk

38 cium-cAMP signaling during fatigue or stress disengage dlPFC recurrent circuits, reduce firing and im

39 ation, and hence was historically assumed to disengage during goal-directed tasks.

40 cognitive performance, rather than becoming disengaged during cognitive tasks.

41 mode network that is engaged during rest and disengaged during cognitive tasks.

42 somerization of allylic alcohols, whereas it disengages during the isomerization of alkenyl alcohols

43 hat enables flies to independently engage or disengage each wing from the mechanically linked thorax.

44 One mechanism, direct suppression, disengages episodic retrieval through the systemic inhib

45 the R-state, loop-engaged and T-state, loop-disengaged forms of FBPase.

46 This observation suggests that Eps15 may disengage from AP-2 during coat formation.

47 are predisposed to readily integrate into or disengage from conserved genetic networks influencing or

48 s indicate that, on stress, ribosomes do not disengage from ER-associated transcripts (puromycin inse

49 CD phenotype, such as patients' inability to disengage from internally-generated scenarios and though

50 in the active site reveals that G1207 has to disengage from its Watson-Crick base pairing interaction

51 ars at the centrosome, procentrioles mature, disengage from mother centrioles, and ultimately duplica

52 k activity and micturition may allow time to disengage from ongoing behaviors unrelated to micturitio

53 These findings suggest that TonB does indeed disengage from the cytoplasmic membrane during energy tr

54 d default mode networks and the inability to disengage from the default mode network may be critical

55 result of the Cu(I)-CsoR mutants failing to disengage from the DNA targets, thus inhibiting the dere

56 r engages poorly processive polymerases that disengage from the DNA template prematurely.

57 sition and maturation, dendritic cells (DCs) disengage from the extracellular matrix, cross basement

58 and the failure of LPFC-lesioned animals to disengage from the immediately preceding response, it is

59 ger individuals, older adults failed to both disengage from the interruption and reestablish function

60 sult arises from our assumption that stators disengage from the motor for a significant portion of th

61 k codon-anticodon pairing allows the tRNA to disengage from the mRNA and slip +1, or an unusual codon

62 ack is necessary for the early-acting CRM to disengage from the promoter so that the late-acting CRM

63 e data showed that helices alpha1 and alpha6 disengage from the rest of the domain, leaving helices a

64 echanisms that rescue polymerases failing to disengage from the template at pA sites.

65 Epithelial cells disengage from their clusters and become motile by under

66 mbryos only start to incorporate Cnn as they disengage from their mothers; this generates a centrosom

67 rylated by src kinases when epithelial cells disengage from their tissue framework, identifying an im

68 " pauses, and that they can also temporarily disengage from these tracks, resulting in more prolonged

69 Inability to disengage from ZO-1 correlated with increased GJ plaque

70 efficiency, suggesting that the inability to disengage from ZO-1 prevented maturation of functional i

71 the tendency to enter into, and inability to disengage from, a negative mood state rather than the mo

72 eightened experience of, and an inability to disengage from, negative emotions in depressive disorder

73 s showed that when interrupted, older adults disengaged from a memory maintenance network and realloc

74 public-sector ART programs in South Africa, disengaged from care at least once in a contemporary 2-y

75 ation, implying that astrocytes were largely disengaged from cortical input in healthy tissue.

76 mplex, in which the mutant HisP subunits are disengaged from HisQ and HisM, suggesting that the resid

77 We also provide evidence that NEMO is disengaged from IKK complex following genotoxic stress i

78 tabilized in an "intermediate" conformation, disengaged from important phosphoryl transfer residues.

79 The phosphorylated regulatory domain is disengaged from its inhibitory position; the nucleotide-

80 19 (6%) patients disengaged from services (12 [7%] of 165 CTOs vs 7 [4%]

81 tter is the most probable when the tandem is disengaged from the catalytic domain.

82 nvalid trials only, when attention had to be disengaged from the distractor and reoriented to the tar

83 Akt in which the PH domain is constitutively disengaged from the kinase domain are phosphorylated at

84 merular basement membrane and, occasionally, disengaged from the parietal basement membrane.

85 n and clarify the fate of the toxin after it disengages from BiP.

86 odel: When the tyrosine-phosphorylated STAT1 disengages from DNA, the ND dimerizes and somehow assist

87 ILY disengages from hCD59 during the prepore to pore transit

88 ATP-BiP disengages from NHK, enabling it to retrotranslocate to

89 Here we probed how BiP disengages from SV40 to enable the virus to penetrate th

90 n of the ternary complex in which the enzyme disengages from the 3' end of the transcript and moves b

91 We show that PolB1 repeatedly disengages from the DNA template, leaving PCNA123 behind

92 d base lesion or, in some cases, its partner disengages from the helix and is bound to the enzyme's a

93 When bound to MHCI, but not MHCII, Valpha disengages from the Jalpha beta strand, switching Valpha

94 depletion, the soluble catalytic V(1) sector disengages from the membrane integral V(o), and at the s

95 the assembly of the prepore oligomer, but it disengages from the receptor upon the conversion to the

96 und that the Pol III* subassembly frequently disengages from the replisome during DNA synthesis and e

97 Following mismatch detection, MutS disengages from the replisome, facilitating repair.

98 We measured the efficiency of disengaging from a central visual stimulus to orient to

99 In particular, disengaging from coping efforts can signal the likelihoo

100 TOs on readmissions and the risk of patients disengaging from mental health services temporarily or e

101 depicts single protein molecules completely disengaging from the network.

102 ol group flexibly adjusted their behavior by disengaging from the newly ineffective action in favor o

103 releases transcripts 2-8 nt in length before disengaging from the promoter and isomerizing to a stabl

104 GAPDH, by engaging/disengaging glycolysis and through fluctuations in its e

105 Force required to disengage guide wires from filters was measured.

106 Here, we used a genetic approach to disengage HIF activation from EPO synthesis and found th

107 However, Asf1 was unable to disengage histones from DNA for tetrasomes formed with H

108 nputs co-engage early in action learning and disengage in a dissociable manner as actions are refined

109 However, by 14 months, longer latencies to disengage in the subset of the risk group later diagnose

110 ltured cells and HDAC1 binding to the AR was disengaged in a DHT-dependent manner.

111 rate that both restraining mechanisms can be disengaged in heteromeric channels to form fast and sens

112 dback loops of the plant circadian clock are disengaged in roots, because two key clock components, t

113 Hydrogen bonding is nearly completely disengaged in the E-dipyrrinone half; yet, the ridge-til

114 ctivated in well-trained rats if they became disengaged in the task and in response to an unexpected

115 rocess, with parts of the brain engaging and disengaging in time.

116 assium glutamate stimulates transcription by disengaging inhibitory polymerase interactions at a sigm

117 ivity is required for successful invasion to disengage interactions between parasite adhesins and hos

118 cular shuttling of mLT-expressing MZ B cells disengaged interactions between these MZ B cells and LTb

119 When disengaged interactions within a receptor are turned on

120 in gene transcription, whereas deacetylation disengages it from the antioxidant response element, the

121 t with the hypothesis that photoexcited CRY2 disengages its C-terminal domain from the PHR domain to

122 zed that photoexcitation derepresses CRY2 by disengaging its C-terminal domain from the N-terminal PH

123 also demonstrate that TRAF2 interactions can disengage JNK signaling from NF-kappaB activation and th

124 SMC head interface, whereas the Wapl subunit disengages kleisin, but only after ATP rebinds.

125 teric inhibitor, which promotes the T-state, disengaged-loop conformation.

126 hibits motility like a molecular clutch that disengages MotA.

127 in a manner similar to that of a clutch, by disengaging motor force-generating elements in cells emb

128 CFTR maturation pathway that is required to disengage nascent CFTR from ER biosynthetic machinery.

129 The E. coli Rho protein disengages newly transcribed RNA from its DNA template,

130 s that initially promote NHEJ and eventually disengage NHEJ.

131 124I ensues, with the R-subunits transiently disengaging, on average, every 515 bp.

132 motors engaged in a tug-of-war resolvable by disengaging one motor species.

133 hat motors at a leading kinetochore abruptly disengage or turn off, leading to a direction reversal.

134 age, but not across individuals who socially disengage or who speak different languages.

135 ecursive intromission attempts when the male disengages or is dislodged from the hermaphrodite genita

136 tional regulators inhibit motility by either disengaging or jamming the stator-rotor interaction.

137 d demonstrate that its amino-terminal domain disengages p53 from Numb, triggering p53 proteolysis and

138 e a neuronal encoding scheme for how anxiety disengages PFC during decision making.

139 The template switch disengages Pol II from DNA and effectively terminates tr

140 e possible role of nucleolytic retraction in disengaging pol III from TFIIIB is discussed.

141 au sequesters the polymerase tail from beta, disengaging polymerase from DNA.

142 sing its cognate sites, sumoylation fails to disengage prebound p53 from DNA.

143 large proportion of the myosin population to disengage rapidly from actin filaments.

144 ng Src to caveolin-rich lipid rafts, thereby disengaging Src from FAK-associated adhesion and signali

145 coupling, suggesting that 2-APB has to first disengage STIM1 before it can directly gate Orai3 channe

146 nction after the enzyme binds nucleosomes to disengage substrate histone tails from nucleosomal DNA.

147 k across the mitochondrial inner membrane to disengage substrate oxidation from ATP production.

148 Inhibition of the disengaged task remains active for a period of time and

149 the allocation of computational resources by disengaging task-irrelevant cortical regions.

150 "two-hit" mechanism in which tau acetylation disengages tau from MTs and also promotes tau aggregatio

151 Consequently, HIV-1 Nef disengages TCR triggering from the generation of p-LAT a

152 A2A adenosine receptors (A2AR) was shown to disengage the critical immunosuppressive mechanism and c

153 el the metastatic population, we are able to disengage the direct dependency of the metastatic burden

154 presence of operative cues (primes), novices disengage the prefrontal cortex and seem to accept the o

155 presence of operative cues (primes), novices disengage the prefrontal cortex and seem to accept the o

156 these changes in allowing the polymerase to disengage the promoter is poorly understood.

157 is movement is blocked the polymerase cannot disengage the promoter.

158 litated by nascent peptide interactions that disengage the ribosome anticodon-codon interactions for

159 ulate the rate at which complexes attempt to disengage the sigma(70):DNA interaction.

160 compressive force) caused the attachments to disengage the tip and slide over the filament, but slidi

161 rearrangement of the dimer interface, which disengages the agonist-induced conformational change in

162 recombination intermediates and in so doing disengages the D-loop structure by cleaving the 3'-invad

163 ction between the two proteins in which FEN1 disengages the Dna2 tracking mechanism.

164 eby swiveling around an alpha-helical linker disengages the His domain from the PEP-binding domain.

165 phosphorylation of human Pgp and mouse Pgp1a disengages the influence which these Pgps have on ICl(sw

166 that chronic impairment of local inhibition disengages the mPFC from its cognitive functions by part

167 sbA, envisions a large-amplitude motion that disengages the nucleotide-binding domains and repacks th

168 ion of the pause hairpin with RNA polymerase disengages the RNA 3' end from the active site.

169 Previously, we demonstrated that FEN1 disengages the tracking mechanism of Dna2 to remove it f

170 c mutations activate FGFRs and other RTKs by disengaging the brake either directly or indirectly.

171 es metastasis and prolongs mouse survival by disengaging the Shh-IL6-RANKL signaling network in strom

172 Of the 9,005 who disengaged, the 2 most common initial outcomes were retu

173 pamycin complex 1 (mTORC1) signaling pathway disengages, the mitochondria network fragments, cristae

174 of circularly arranged F protein trimers may disengage them from pulling the membrane centrifugally,

175 However, FEN1 disengaged these nonproductively bound Dna2 molecules, p

176 ic TolB, which, as recent evidence suggests, disengages TolB from its interaction with other componen

177 peptides that are unable to conformationally disengage TPN from class I molecules are excluded from t

178 dic reaction times, and reduced latencies to disengage visual attention.

179 ly developing toddlers had more difficulties disengaging visual attention from faces than toddlers wi

180 in response to the ion motive force, clearly disengage when conditions change.

181 distinct kinds of memories: (1) one that was disengaged when the brain detected a change in the task

182 ly in centrioles that were both modified and disengaged, whereas unmodified centrioles, engaged or no

183 -cadherin by means of their adaptors became "disengaged" while their protein levels were significantl

184 RTICLE: Brain regions dynamically engage and disengage with one another to execute everyday actions f

185 aged most frequently overall (P < .0005) but disengaged with forces not significantly different (P >

186 T in human cells with long telomeres that is disengaged with increased cell divisions as telomeres pr