ライフサイエンスコーパス: disjunction

1 kely reflect mechanisms to ensure chromosome disjunction.

2 nteractions which can lead to chromosome non-disjunction.

3 d chromosomes 21 involved in paternal MI non-disjunction.

4 exchanges makes a tetrad susceptible to non-disjunction.

5 junction; and (iii) those leading to MII non-disjunction.

6 ids and a reduced efficiency of distributive disjunction.

7 osomes lacking homology do not pair prior to disjunction.

8 nonexchange chromosomes are paired prior to disjunction.

9 , and destroyed to complete sister chromatid disjunction.

10 ased risk for UPD in the case of meiotic non-disjunction.

11 om chromosomes and triggers sister-chromatid disjunction.

12 with separase, both failed to induce sister disjunction.

13 are an important contributor to meiotic non-disjunction.

14 re, overexpression of Mad2 inhibited homolog disjunction.

15 e product is essential for proper chromosome disjunction.

16 mitosis was not sufficient to trigger sister disjunction.

17 tor genes, which mediate faithful chromosome disjunction.

18 is an important factor for X chromosome non-disjunction.

19 e know little of the causes of mammalian non-disjunction.

20 ch the Wt Y chromosome is susceptible to non-disjunction.

21 idence for a genetic effect on mammalian non-disjunction.

22 omosomes may be at an increased risk for non-disjunction.

23 ination and to determine their impact on non-disjunction.

24 cally, including three STs with transoceanic disjunctions.

25 stakes" dispersal accounts for many of these disjunctions.

26 densation but nonetheless allowed chromosome disjunction, anaphase B, and formation of a cytokinetic

27 POLES, ESP) plays a major role in chromatid disjunction and cell expansion in Arabidopsis thaliana.

28 correlation was found between mitral annulus disjunction and curling (R=0.85).

29 mple and direct connection between defective disjunction and defective sperm development.

30 otic recombination, decreased chromosome non-disjunction and improved spore viability.

31 berates separase triggering sister chromatid disjunction and inactivates cyclin-dependent kinase 1 (C

32 mary counts, and functional summaries of the disjunction and intersection of clusters shared between

33 lar dominant effect on achiasmate chromosome disjunction and mapped the haplo-insufficient meiotic ge

34 driving mitotic events, including centrosome disjunction and separation, and is frequently over-expre

35 , I present an analysis of extensive data on disjunction and sperm survival in rDNA-deficient males c

36 nts (anaphase A, anaphase B, and chromosomal disjunction) and nuclei reentered interphase quickly eve

37 pecializing in homolog pairing, the other in disjunction-and each producing both noncrossovers and cr

38 vents; (ii) meiotic events leading to MI non-disjunction; and (iii) those leading to MII non-disjunct

39 factors associated with both MI and MII non-disjunction appear to be different for virtually every c

40 aphy resulting in a distant intercontinental disjunction are poorly understood.

41 mata, that are required to ensure chromosome disjunction, arise via the class I interference-dependen

42 spect of meiotic prophase I that aids proper disjunction at anaphase I.

43 c chromosomal functions necessary for proper disjunction at meiosis I.

44 available, the extra Y was generated by non-disjunction at meiosis II after a normal chiasmate meios

45 o either a post-zygotic mitotic error or non-disjunction at meiosis II after a nullichiasmate meiosis

46 required during DNA replication, chromosome disjunction at mitosis, and other DNA-related activities

47 ibition is necessary for complete chromosome disjunction, because ribosomal RNA (rRNA) transcripts bl

48 The disjunction between arrestin recruitment and internaliza

49 ee alternative hypotheses to account for the disjunction between modern and archaeological herring po

50 This disjunction between phenology at low and high altitudes

51 oal-directed action propose that experienced disjunctions between an action and its specific conseque

52 ivo target coverage was not practical due to disjunctions between enzyme and cell data, complex and a

53 es that mediate the influence of experienced disjunctions between these events are unknown.

54 een offered is that pairing not only ensures disjunction, but also changes the physical state of chro

55 uish between the different mechanisms of non-disjunction by analysing DNA polymorphisms at the distal

56 cyclin A degradation facilitates chromosome disjunction, cyclin B destruction is required for anapha

57 proteolysis at the time of sister chromatid disjunction destabilizes kinetochore-microtubule attachm

58 a Ca(2+)-dependent manner whereas non-claret disjunction, Drosophila kinesin, and KCBP that lack a CB

59 ls of the chromokinesin NOD (no distributive disjunction; Drosophila melanogaster kinesin-10).

60 ms: p53 inactivation and abnormal chromosome disjunction due to telomere fusions (TFs).

61 cks in preparation for homologous chromosome disjunction during anaphase I.

62 at the metaphase plate and their subsequent disjunction during anaphase I.

63 role for Aurora B in telomere dispersion and disjunction during fission yeast mitosis.

64 romosomes is necessary for proper chromosome disjunction during meiosis I.

65 her, creating chiasmata that ensure accurate disjunction during reductional division.

66 Disjunction efficiency decreases linearly as heterochrom

67 classifying cases according to stage of non-disjunction error.

68 s well as a high frequency of chromosome non-disjunction errors leading to aneuploidy (50%) in the oo

69 or (I or II) and the individual in which non-disjunction event occurred, as well as the crossover loc

70 ivative 22 syndrome owing to 3:1 meiotic non-disjunction event.

71 Surprisingly, the non-disjunction events are largely restricted to the earlies

72 s occurring at MI, and suggests that all non-disjunction events may be initiated during MI and simply

73 rnal meiosis I (MI) and meiosis II (MII) non-disjunction events.

74 we show that a novel chromatin factor, X non-disjunction factor 1 (xnd-1), is responsible for the glo

75 le, at least four were due to meiosis II non-disjunction following a normal chiasmate meiosis I.

76 the first analysis of recombination and non-disjunction for a large paternally derived population of

77 al loss of APC/Apc: mutation in APC/Apc, non-disjunction, homologous somatic recombination and epigen

78 d genera (eastern Asia-eastern North America disjunction) implies significant periods of separation s

79 itral annulus showed a longer mitral annulus disjunction in 50 sudden death patients with MVP and LV

80 large proteins that mediate sister chromatid disjunction in all eukaryotes.

81 PICH(-/-) cells undergo sister chromatid non-disjunction in anaphase, and frequently abort cytokinesi

82 rements for achiasmate (nonexchange) homolog disjunction in Drosophila female meiosis I have been ide

83 During fieldwork, we found a substantial disjunction in flowering time that is correlated with so

84 first molecular correlate identified for non-disjunction in humans.

85 address the underlying causes of meiotic non-disjunction in humans.

86 chromosomes exhibit an absence of chromosome disjunction in meiosis I and an infrequent chromosome di

87 help prepare the chromosome pairs for proper disjunction in meiosis I.

88 on in meiosis I and an infrequent chromosome disjunction in meiosis II.

89 l recombination appears to predispose to non-disjunction in MI, the presence of a proximal exchange p

90 ce of a proximal exchange predisposes to non-disjunction in MII.

91 adjacent to a region of intron I at which a disjunction in sequence similarity between RBCS1B and RB

92 es and the mechanisms that ensure chromosome disjunction in the absence of recombination.

93 romosomal interactions that promote accurate disjunction in the first of two segregation events to ge

94 rt a highly significant association: MII non-disjunction involves increased recombination that is lar

95 Explanations for biogeographic disjunctions involving South America and Africa typicall

96 Mitral annulus disjunction is a constant feature of arrhythmic MVP with

97 ansposon silencing, while meiotic chromosome disjunction is affected in rsd-6 mutants.

98 se results, we propose that sister-chromatid disjunction is often incomplete in human cells even afte

99 rinsic defect; however, the incidence of non-disjunction is significantly influenced by strain backgr

100 tween altered recombination and maternal non-disjunction is well documented: reductions in recombinat

101 ble cyclin A prolonged or blocked chromosome disjunction, leading to metaphase arrest.

102 The defect in distributive disjunction may be attributable to overloading of the di

103 eneral complete bipartite graphs and logical disjunctions may be of broader use than that the specifi

104 Mitral annulus disjunction (median: 4.8 versus 1.8 mm; P<0.001), end-sy

105 The error of disjunction must occur either during paternal meiosis II

106 est to determine when errors of Y chromosome disjunction occur.

107 Chromosome disjunction occurred normally, but anaphase-like movemen

108 one crossover per bivalent, below which non-disjunction occurred.

109 combination are associated with maternal non-disjunction occurring at both meiosis I (MI) and meiosis

110 P1 and cohesin Rad21 from telomeres, whereas disjunction occurs at anaphase after the phosphorylation

111 segregation system helps to ensure faithful disjunction of autosomes during spermatogenesis.

112 Paternal non-disjunction of chromosome 21 accounts for 5-10% of Down

113 The cause of non-disjunction of chromosome 21 remains largely unknown.

114 age, distinguishing our results from MII non-disjunction of chromosomes 18 or 21.

115 en homologous chromosomes facilitates proper disjunction of chromosomes during meiosis I.

116 lin A degradation, and functions to time the disjunction of chromosomes in the early embryo.

117 In these cells, taxol did not inhibit the disjunction of chromosomes nor prevent their poleward se

118 nalyzing each subset defined by the union or disjunction of groups within the Venn diagram, and inclu

119 d appears to promote crossing over to ensure disjunction of homologous chromosomes.

120 Both disjunction of mini-X pairs and multivalent formation ar

121 D, provides a tool with which to explore the disjunction of mitosis and cytokinesis in cell cultures,

122 Bub1 and 3, and Mps1, may prevent premature disjunction of sister chromosomes, the other, consisting

123 sed cyclin A proteolysis and delayed mitotic disjunction of sister chromosomes.

124 A disjunction of such motifs often can represent the entir

125 tionally implicated in the regulation of the disjunction of the centrosome, the assembly of the mitot

126 The inseparabile mutation also affects disjunction of the chromosome 4 in males.

127 Mitotic disjunction of the repetitive ribosomal DNA (rDNA) invol

128 here are at least two mechanisms causing non-disjunction of the Y chromosome.

129 ttern evolved recently and expanded, causing disjunctions of more ancestral patterns.

130 Examples include intercontinental disjunctions of tropical plants, the spread of plant lin

131 e N or C terminus of a minus-end (non-claret disjunction) or C terminus of a plus-end (Drosophila kin

132 oup I and group II, repair during pachytene (disjunction pathway) is associated with interference and

133 The non-disjunction phenotype has both cis and trans components:

134 vity or securin can prevent sister chromatid disjunction, principally by overexpression of non-degrad

135 e earliest cell divisions in mammals are non-disjunction-prone, an interpretation which provides an e

136 at in addition to promoting accurate homolog disjunction, recombination can also function to partiall

137 Given this disjunction, regulating those advertisements may be an a

138 Efficient disjunction requires 1000 kilobases of overlap in the ce

139 they suggest that virtually all maternal non-disjunction results from events occurring in meiosis I.

140 kinase 2 (Nek2), which regulates centrosome disjunction/splitting, binds to and phosphorylates beta-

141 e dispersion initiates in metaphase, whereas disjunction takes place in anaphase.

142 predicted, children (as per logic of negated disjunction) tended to increase their speed of checking

143 ons are associated with a higher risk of non-disjunction than others.

144 tes, allowing these insects to cross habitat disjunctions that would have represented major or comple

145 ii) mitotic checkpoints regulate chromosomal disjunction to generate fissioned karyotypes.

146 efore investigated maternal X chromosome non-disjunction, to determine whether the effects of recombi

147 A high frequency of sex chromosomal non-disjunction, unrelated to the BN: mutation, was also ide

148 ase A of meiosis I, thus preventing complete disjunction until mid- to late anaphase A.

149 omenon, which is called preplay, occurred in disjunction with sequences of replay of a familiar exper