ライフサイエンスコーパス: disk membrane

1 ation of 11-cis-retinal complexes across the disk membrane.

2 directly coupled as it is in the native rod disk membrane.

3 cteristic of classical Meta II in the native disk membrane.

4 encounter frequency between proteins on the disk membrane.

5 chain packing in the rod outer segment (ROS) disk membrane.

6 ted to be the sole species present in native disk membranes.

7 e PM renewal is coordinated with that of the disk membranes.

8 from the lumen to the cytoplasmic leaflet of disk membranes.

9 f two compartments: plasma membrane (PM) and disk membranes.

10 psin, may indeed exist as a homodimer in rod disk membranes.

11 cribed monomer, in retinal rod outer segment disk membranes.

12 der found in native bovine rod outer segment disk membranes.

13 336 of peripherin/rds localized uniformly to disk membranes.

14 P phosphodiesterase (PDE6) at the surface of disk membranes.

15 cesses inhibited the ingestion of additional disk membranes.

16 oxidative damage of DHA-PC in photoreceptor disk membranes.

17 niformly distributed and freely diffusing on disk membranes.

18 activated, unphosphorylated rhodopsin in ROS disk membranes.

19 x in the rims of photoreceptor outer segment disk membranes.

20 een shown to directly mediate fusion between disk membranes and opposing membranes to maintain the hi

21 For rod disk membranes and recombinant membranes containing rhod

22 g a photoconversion technique, we found that disk membranes are assembled at the base of cone-shaped

23 The disk membranes are continually renewed, but how new disk

24 Rod outer segment disk membranes are densely packed with rhodopsin.

25 the T(m) of rhodopsin and of opsin in native disk membranes, as well as in cross-linked disk membrane

26 data of nascent and mature rod photoreceptor disk membranes at unprecedented z-axis depth and resolut

27 imply from partial solubilization of the ROS disk membranes because detergent-treated low buoyant den

28 r rhodopsin bleaching moved laterally in the disk membrane bilayer with an apparent diffusion coeffic

29 recoverin facilitates its binding to retinal disk membranes by a mechanism known as the Ca(2+)-myrist

30 ilitates the binding of recoverin to retinal disk membranes by a mechanism known as the Ca2+-myristoy

31 allow rhodopsin to be examined in the native disk membranes by a number of methods.

32 ely involved in the removal of outer segment disk membranes by the RPE.

33 but not all, of this complex is tethered to disk membranes by the transmembrane protein R9AP.

34 in phototransduction that take place on the disk membrane, by restricting the lateral movement of, a

35 -Dendra2 was also trafficked from old to new disk membranes, consistent with the hypothesis that retr

36 Rod disk membranes containing different average receptor pho

37 gests that the local density of rhodopsin in disk membranes could be much higher than the average den

38 highest temperature was detected for native disk membranes: di22:6-PC < 16:0,22:6-PC < di16:0,18:1-P

39 PP-5 was able to inhibit R18-PM disk membrane fusion and promoted ANTS/DPX contents mixi

40 is unlikely mediated by diffusion, since the disk membranes have a closed configuration, as evidenced

41 Ca(2+) is high, and to be released from the disk membrane in light when Ca(2+) is low, accelerating

42 umulation of 11-cis-retinal in photoreceptor disk membranes in excess of what is required for visual

43 quired for the normal processing of ingested disk membranes in the RPE, primarily in the basal transp

44 e disk membranes, as well as in cross-linked disk membranes in which rhodopsin dimers are known to be

45 ated channel in the PM, while preventing the disk membrane incorporation.

46 gestion of photoreceptor outer segment (POS) disk membranes, is a major role of the retinal pigment e

47 e PM domains, which are the proposed site of disk membrane maturation.

48 which are known to disrupt F-actin-dependent disk membrane morphogenesis, prevented the entrance of n

49 aments, both of which play critical roles in disk membrane morphogenesis.

50 embrane components contributes to the larger disk membrane observed toward the base of the cone-shape

51 the G protein-coupled receptor rhodopsin on disk membranes of living rod photoreceptors from transge

52 Rhodopsin in the disk membranes of rod outer segments serves as the dim-l

53 gether with its specific localization to the disk membranes of the rod cell, has also enabled direct

54 vestigate the effect of partial bleaching of disk membranes on the T(m) of rhodopsin and of opsin in

55 To visualize the dynamic reorganization of disk membranes, opsin and peripherin/rds were fused to a

56 18-labeled ROS plasma membrane (R18-PM) with disk membranes or peripherin/rds-enriched large unilamme

57 to the membrane evaginations believed to be disk membrane precursors.

58 We discuss how pathological alterations of disk membrane properties by mutant proteins may lead to

59 otein constituting >90% of rod outer segment disk membrane protein.

60 not affect the localization of outer segment disk membrane proteins, such as rhodopsin, Peripherin-rd

61 from homogenates of rod outer segment (ROS) disk membranes purified free of the surrounding plasma m

62 e dual wavelength absorbance response of rod disk membrane (RDM) suspensions to a series of small ble

63 In the bleached bovine rod disk membranes (RDM), opsin and membrane lipids were dom

64 We conclude that in native disk membranes, rhodopsin behaves predominantly as a mon

65 iliary PM, and coordinates the formations of disk membrane rim region and OS PM.

66 n processes associated with the formation of disk membranes, specialized organelles of photoreceptor

67 role in the morphogenesis and maintenance of disk membrane structure, with peripherin/rds gene mutati

68 in the maintenance of photoreceptor rod cell disk membrane structure.

69 high-curvature rim domains of outer segment disk membranes suggests that it may act to shape these s

70 notion of raft or microdomain structures in disk membranes suggests that the local density of rhodop

71 RK in a ternary complex on rod outer segment disk membranes, thereby blocking RK interaction with rho

72 odopsin in detergent-solubilized retinal rod disk membranes, using 1-5 pmol of digest per sample.

73 inal domain of RGS9-1, and anchors it to the disk membrane via a C-terminal transmembrane helix.

74 ral solutes on acyl chain packing in the ROS disk membrane was assessed via measurements of the fluor

75 A portion of the ROS disk membrane was found to be resistant to Triton X-100

76 trast, the T(m) of cross-linked rhodopsin in disk membranes was dependent on the extent of bleaching.

77 Moreover, the outer segment disk membranes were greatly overgrown and misoriented, i

78 Moreover, fewer packets of disk membranes were ingested in vivo, possibly because r

79 contribution to rhodopsin kinetic stability, disk membranes were systematically disrupted by octyl-be

80 e fascia adherens region of the intercalated disk membrane, while N-RAP extends approximately 100 nm

81 e polyunsaturated nature of phospholipids in disk membranes, with rhodopsin/lipid ratios ranging from