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1 h levels of PCM are unaffected, it is highly disorganized.
2 re expanded and the extracellular matrix was disorganized.
3 ly absent and those remaining are completely disorganized.
4 ded into 3 domains: psychotic, negative, and disorganized.
5 mited kDNA shrinkage but the networks become disorganized.
6 the pyrenoid of cia6 mutant cells is highly disorganized.
7 egment (OS) lamination, when detectable, was disorganized.
8 an ankyloglossia, and lingual mesenchyme is disorganized.
9 In contrast, cochlear hair cell polarity is disorganized.
10 icient mice was edematous, hypocellular, and disorganized.
11 Peripherin staining was irregular and disorganized.
12 In addition, axons in the motor cortex were disorganized.
13 , and their synchondrosis growth plates were disorganized.
14 at sites of adhesion, although occasionally disorganized.
15 riched in conditions in which the spindle is disorganized.
16 activity is abrogated, septins are partially disorganized.
17 ry coupling is too weak, spike timing is too disorganized.
18 s appear, the HA spikes become conspicuously disorganized, a layer of M1 matrix protein is no longer
19 n early stage in fro mutants, leading to the disorganized accumulation of actin, myosin, and alpha-ac
20 c mice exhibited increased bacterial burden, disorganized accumulation of lymphocytes and mononuclear
22 ls but decreased cellular F-actin content, a disorganized actin cytoskeleton, impaired chemotaxis, an
26 mic axons are delayed, overfasciculated, and disorganized along their pathway through the ventral tel
29 mitosis, sparse cytoplasm, fewer ribosomes, disorganized and clumped organelles, and large vacuoles-
30 , however, the motor pools become temporally disorganized and coupling between independent respirator
32 bp1(+/-) mice, ER stress was associated with disorganized and dilated ER, loss of zymogen granules, a
33 embryonic vasculature of mutant animals were disorganized and displayed decreased microvascular densi
36 d with controls, Col12a(-/-) osteoblasts are disorganized and less polarized with disrupted cell-cell
41 ed to pattern the new organ, as mutants show disorganized and reduced number of layers and tissue ini
42 In mice lacking Shroom3, the epithelium is disorganized and temporarily stratified during villus em
43 ow that protrusion and adhesion dynamics are disorganized and that vesicular trafficking to the tip o
44 tions: photoreceptor synapses in the OPL are disorganized and the retinal physiological response is a
45 llagen fibrils in Fam20C-deficient bone were disorganized and thicker while the growth plate cartilag
47 g to their glycoprotein arrays (organized or disorganized) and whether or not they have a resolved M1
48 d psychiatric symptoms (psychotic, negative, disorganized, and depressive) were made at each assessme
49 e, three symptom factors (positive, negative/disorganized, and mood) were identified with exploratory
52 related to helpless/inadequate, overwhelmed/disorganized, and special/overinvolved countertransferen
54 DNA damage and cell death in spermatogonia, disorganized apical ectoplasmic specialization, malforme
55 s may shed light on the circuitry underlying disorganized appetitive responses in psychopathology; e.
56 gs and contain smaller ovaries with a highly disorganized arrangement of ovarioles in comparison to w
59 ivity resulted in misaligned neuroblasts and disorganized astrocytes in the RMS/SVZ, linking EphA4 fo
66 find that ric-8a mutation in mice results in disorganized Bergmann glial scaffolding, defective granu
67 lagen IV and pan-laminin were present in the disorganized BM of isolated islets, yet a significant re
70 metanephric mesenchyme leads to ectopic and disorganized branching morphogenesis caused by beta-cate
71 n the proliferation level of salivary cells, disorganized branching morphogenesis, and a lack of diff
73 ctin cytoskeleton (F-actin) in HeLa cells is disorganized by NHERF1, whereas actin protein expression
76 er, the sarcomeres were abnormally small and disorganized, causing skeletal muscle hypoplasia and per
77 e somatic proliferation leading to numerous, disorganized cell layers, suggesting a synergistic inter
79 ation of EC adhesion, as its loss results in disorganized cell-cell junctions and reduced focal adhes
82 eft-right asymmetry of coelomic pouches, and disorganized circumesophageal muscle causing an inabilit
84 conditional knockout mice presented severely disorganized collagen fibers and neovascularization in t
85 alone or in the absence of a scaffold showed disorganized collagen formation and poor tissue healing.
86 Clinical high risk criteria that emphasize disorganized communication and suspiciousness while also
87 idity of 81.8%, consisted of four variables: disorganized communication, suspiciousness, verbal memor
88 isphere was relatively spared, subjects with disorganized community structure had significantly worse
89 lls of these irx15 irx15l double mutants are disorganized, compared with the wild type or other previ
90 maintained fdx5 mutant cells became severely disorganized concomitant with a marked decrease in the r
93 erning of the cortical sheet, such as highly disorganized cortical lamination in reeler, led to spect
95 e induced overexpression of NEK6 reduced and disorganized cortical microtubules and suppressed cell e
97 essive elongation of F-actin, resulting in a disorganized cytoskeleton and reduced cell polarity, whi
98 The combined arrested differentiation and disorganized cytoskeleton of PIP5KIgamma-transduced oste
100 ng with abnormal collagen fibril morphology, disorganized dermal architecture, and reduced skin stren
102 lopment, cortical activity is far from being disorganized, despite the presence of long periods of ne
106 The cervical extracellular matrix must be disorganized during labor to allow birth, followed by a
107 rammed neurons are dissociated and spatially disorganized during transplantation, rendering poor cell
109 ditionally characterized by spatiotemporally disorganized electrical activation and, although initiat
110 res, interictal epileptiform activity with a disorganized electroencephalography background, developm
111 d in Cited2 null embryos is due in part to a disorganized embryonic capillary network, and in part du
112 also observed in Scl(-/-) hearts, where the disorganized endocardium precociously differentiated int
115 k sac primary capillary plexus formation and disorganized endothelial cell patterning in FAK(R454/R45
116 phosphorylated cortactin are not detected in disorganized Epha2(-/-) cells with altered F-actin distr
117 skin models was associated with acanthosis, disorganized epidermal architecture, and downregulation
119 e to adequately nourish their pups, due to a disorganized epithelial compartment within their mammary
120 i-1 function in wild-type embryos results in disorganized epithelial migration and occasional morphog
121 ulbs, reduced olfactory sensory neurons, and disorganized epithelial ultrastructure in Chd7 mutant mi
122 RTCB-depleted plasma cells show reduced and disorganized ER structures as well as severe defects in
124 L3 and wing marginal veins and increased and disorganized expression of wingless, the central compone
126 atrix, whereas few myofibroblasts and little disorganized extracellular matrix were noted in eyes tha
127 yes that had -9.0D PRK, along with prominent disorganized extracellular matrix, whereas few myofibrob
128 of perlecan and semaphorin 3C, and exhibited disorganized F-actin stress fibers within the aorticopul
129 the PGC data set; for MGS subjects, negative/disorganized factor scores were correlated with polygeni
130 s based on MGS GWAS results for the negative/disorganized factor were significantly different between
132 associated with increased interpersonal and disorganized features of schizotypal personality at age
134 ssion of CM basement membrane components and disorganized fibrillar collagen matrix, independently of
135 simus resulted in muscle histopathology with disorganized fibrosis that often colocalized with fatty
137 1 at both metaphase and anaphase, leading to disorganized gamma-tubulin recruitment in centrosomes.
138 Bulbs were smaller and presented fewer and disorganized glomeruli and a significant reduction in mi
140 tuberculosis infection, db/db mice exhibited disorganized granulomas, neutrophilia, and reduced B cel
141 we used the Smad1/5(CKO) mutant mouse, whose disorganized growth plate is due to the conditional dele
143 uditory brainstem response, displayed highly disorganized hair-cell stereocilia and had no detectable
145 ng gene expression profiles of polarized and disorganized human mammary epithelial cells in a physiol
146 ed increases in beta-cell VEGF levels led to disorganized, hypervascularized, and fibrotic islets, pr
151 ial CXL; similarly, collagen fibers appeared disorganized in keratoconus, while their pattern appears
153 s were disorganized in VAD mice and were not disorganized in Rpe65(-)/(-) mice, although they were sh
154 icroscopy revealed fiber membranes that were disorganized in the lenses of VIM(SA/SA), reminiscent of
157 at the outer segments of photoreceptors were disorganized in VAD mice and were not disorganized in Rp
158 Although hindbrain floor plate cilia are disorganized in vangl2 mutant embryos, cilia appear to b
159 e defect in the hippocampus, a shortened and disorganized infrapyramidal bundle of the mossy fiber pr
165 is of angle structures, and a hypoplastic or disorganized iris were also observed in the 3 cases.
166 This phenotype was accompanied by a highly disorganized lamellar actin network and rescued by the a
167 layer and the basement membrane, leading to disorganized lamination and an absence of cerebellar fol
169 65/FE65L1 double knockout (DKO) mice display disorganized laminin in meningeal fibroblasts and a cobb
170 2-knockout models had a small forebrain with disorganized layering of neurons and nuclear shape abnor
171 rmation explains how EphA2 mutations lead to disorganized lens cells that subsequently contribute to
172 in shortened body axis, microphthalmia with disorganized lens, microcephaly, reduced touch-evoked mo
173 inhibition of AM signaling revealed markedly disorganized lymphatic junctional proteins ZO-1 and VE-c
174 rmal lymphatic patterning and in dilated and disorganized lymphatic vessels in all tissues examined a
175 milarly, formation of hyperproliferative and disorganized mammary acini induced by chronic stimulatio
176 rozygous female mice are fertile but contain disorganized mammary epithelial cells, in which zonal oc
178 bryos lacking Tal1, endocardial cells form a disorganized mass within the ventricle and do not popula
179 tors fails to differentiate and develop into disorganized masses resembling acinar to ductal metaplas
181 iates from triggers by organized rather than disorganized mechanisms, either via spiral wave re-entry
182 Lack of Sin expression correlated with a disorganized medullary architecture and fewer functional
183 ved mouse embryonic fibroblasts have visibly disorganized membranes, unprocessed internal vesicles an
184 ilencing of Sox102F led to misorientated and disorganized michrochaetes, neurons with shorter dendrit
185 tissues by identifying the heterogeneous and disorganized microscopic tissue structures indicative of
186 sent during clot formation produce a visibly disorganized microstructure that increases clot stiffnes
188 on outgrowth and growth cone turning, due to disorganized microtubules that fail to enter filopodia a
189 s terminally specified neurons with severely disorganized microtubules, microfilaments and neurofilam
191 evelops presumptive hair cells with numerous disorganized microvilli instead of ordered stereocilia.
192 scopy (TEM) revealed myofibril degeneration, disorganized mitochondrial cristae, lipid inclusions and
193 is revealed that Parkin-deficient hearts had disorganized mitochondrial networks and significantly sm
194 ence during cell division is associated with disorganized mitotic chromosome movements and chromosome
202 ne turning in Wnt5a gradients, likely due to disorganized MTs that failed to extend into the peripher
206 MGRKO and GR(-/-) mice at E17.5, with short, disorganized myofibrils and cardiomyocytes that fail to
208 into the developing eyefield in vivo, led to disorganized nerve ring formation and premature cornea i
212 BS mutation in yeast (eco1-W216G) exhibits a disorganized nucleolus and reduced looping at the rDNA.
214 elopment based on a rough-eye phenotype with disorganized ommatidia observed in adult escapers of the
215 uffices in predicting the self-organized and disorganized orientation maps from primates to rodents.
216 tology and electron microscopy (EM) revealed disorganized OS as early as 3 weeks with complete loss b
217 cific reduction in outer rod segment length, disorganized outer rod segment discs, and mislocalizatio
218 aggregate formation during stage 9 (S9), and disorganized parallel actin filament bundles during stag
219 ockdown display dysfunctional cilia and show disorganized patterning, mislocalization of junctional m
221 wing that cystogenesis was associated with a disorganized pericystic network of vessels expressing pl
226 nce of progressive retinal degeneration with disorganized POS and thinning of the outer nuclear layer
227 tic Morphology-1) results in fewer synapses, disorganized presynaptic architecture, and axon overexte
228 atient with renal disease have elongated and disorganized primary cilia and that this ciliary phenoty
230 s and proximal axons of spinal cord neurons, disorganized processes in the cerebellum and abnormal pr
232 -dimensional model of breast carcinogenesis, disorganized, proliferative transformed breast epithelia
235 primary root of atdfb was associated with a disorganized quiescent center, dissipated auxin gradient
238 h other mutations had poorly defined PSJ and disorganized retinal lamellar structures, where only one
239 s, as cells expressing SpAin1(R216E) display disorganized ring material and delays in both ring forma
240 ype of cc2d2a mutant zebrafish consisting of disorganized rod and cone photoreceptor outer segments r
243 bited early-onset retinal degeneration, with disorganized ROS structures, autofluorescent deposits in
244 eatures of CM dedifferentiation, including a disorganized sarcomere network, rounding, and conspicuou
246 tbd5 null mice have smaller muscle fibers, a disorganized sarcomeric structure, increased extracellul
248 initially classified as having catatonic or disorganized schizophrenia were reclassified as having m
249 ed correlations between dopamine release and disorganized schizotypal traits in the striatum, thalamu
250 markedly abnormal pattern of high-amplitude, disorganized slow activity with frequent generalized and
251 mpaired contractility, shortened intestines, disorganized smooth muscle cells, and an increase in apo
252 and other brain regions, paranoid delusions, disorganized speech, deficits in auditory gating (i.e.,
253 ls, we observed an increase in the number of disorganized spindle microtubules owing to multipolar co
254 SRP1 inhibits the growth of MTs and leads to disorganized spindle structures, reduction of K-fibers a
258 men from an affected individual demonstrated disorganized stromal lamellae and stromal staining with
260 n addition, cytoplasmic actin filaments were disorganized, suggesting links between the nuclear lamin
261 t related to genetic effects on negative and disorganized symptoms (i.e., core features of chronic sc
262 5; 95% CI, 1.258-2.732; P = .002), and total disorganized symptoms (OR, 5.06; 95% CI, 1.548-16.527; P
263 s displayed an aberrant mitotic spindle with disorganized, tangle-shaped microtubules and reduced ast
264 -shaped t-tubule vesicles, as well as highly disorganized terminal cisternae of sarcoplasmic reticulu
266 th the function of E-cadherin in macrophages disorganized the granulomas and protected the fish, intr
267 microscopy demonstrated that knockdown of NS disorganized the nucleolar architecture, in particular,
268 tubules; in their absence, microtubules were disorganized, the axonal kinesin UNC-104 invaded dendrit
271 thunderstorms, with decreasing deposition in disorganized thunderstorms, quasi-linear convective syst
272 ssion, as cessation of 4HT treatment induced disorganized tissue architecture and p21-associated diff
276 ons, we show that patient tumour vessels are disorganized, tortuous and approximately 50% do not supp
277 s does not prevent secretion, but results in disorganized trafficking and fusion between secretory ve
278 w shear stress due to poor blood flow in the disorganized tumor vasculature induces expression of CLE
280 heterozygous for the human allele displayed disorganized ultrastructural properties of the aortic wa
281 We infer from these results that irregular, disorganized variations in matrix mechanics, compared wi
283 These findings contrast sharply with the disorganized vasculature elicited by induction of vascul
284 however, loss of epsins 1 and 2 resulted in disorganized vasculature, significantly increased vascul
285 e in noncontractile hearts and observed that disorganized ventricular conduction could affect cardiom
287 the chromosome arm and an increase in highly disorganized "wavy" chromosomes that exhibit an "open" o
289 nd that the ventral telencephalon was highly disorganized with intermingling of distinct neuronal cel
291 adins structure appeared to be progressively disorganized with the temperature increase up to 100 deg
293 Dicer1(loxP/loxP);Villin-Cre mutant mice is disorganized, with a decrease in goblet cells, a dramati
294 s of the pronephric duct in ift mutants were disorganized, with a pattern suggestive of defective pla
296 optic nerve and the posterior commissure are disorganized, with the optic nerve failing to reach its
298 rgery), having no or few myelin layers, were disorganized within a fibroblast-rich collagenous scar.
299 enchymal cells of the early limb bud are not disorganized within the ectoderm as previously thought b
300 aming and nemaline-like bodies adjacent to a disorganized Z-line on electron microscopy, recapitulati
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