ライフサイエンスコーパス: dispensable

1 esting that the disulfide bond might also be dispensable.

2 ript, and inhibitory, for which glutamate is dispensable.

3 n, indicating that this canonical pathway is dispensable.

4 the caspase-1-ASC axis, whereas caspase-8 is dispensable.

5 ng cGVHD, while germinal center formation is dispensable.

6 suggest that most miRNAs are phenotypically dispensable.

7 kpoint activity and Cdc20(A) binding becomes dispensable.

8 and polypeptide-binding functionalities are dispensable.

9 Nodal signalling, whereas BMP signalling is dispensable.

10 y, here we show that in some cases it can be dispensable.

11 le amino-terminal domains including NLS1 are dispensable.

12 le amino-terminal domains including NLS1 are dispensable.

13 n is limited to mesothelial cells, which are dispensable.

14 hila growth within macrophages while LbtU is dispensable.

15 , such as nicotinamide or nicotinic acid, is dispensable.

16 phate, whereas MAPK and Ca(2+) signaling are dispensable.

17 whereas, at 30 degrees C, the proteasome is dispensable.

18 or IL-23 signaling, whereas Tyk2 seems to be dispensable.

19 veral model systems, whereas Nur77 was often dispensable.

20 ng mtDNA transcription, but it appears to be dispensable.

21 r normal piRNA biogenesis in germ cells, are dispensable.

22 is sufficient for inducing cGVHD while GC is dispensable.

23 most conserved domain, the CENP-C motif, is dispensable.

24 By contrast, ANGPT2 was dispensable, although mice deficient in both Angpt1 and

25 elopment, while stable MOB1/Hippo binding is dispensable and MOB1/Trc binding alone is insufficient.

26 We find spindle poles are largely dispensable, and in fact act as brakes for chromosome se

27 riments demonstrate that PSE_a and PSE_b are dispensable, and only VPE is required for optimal Eomes

28 Here, we demonstrate that LDs are dispensable as a membrane source for autophagy, but fulf

29 This indicates that DCs are dispensable as APCs for protective immunity against LCMV

30 served, polarity is nonetheless functionally dispensable at several positions.

31 TATEMENT Sexual maturation and fertility are dispensable at the individual level but critical for spe

32 omprise distinct unstable chromosomes called dispensable chromosomes (DCs) that also contribute to ch

33 have diverse affects and (i) may be entirely dispensable (CXCL13, CXCL16), (ii) may promote (CXCL10,

34 d sufficient in utero to suppress p53 but is dispensable during adulthood.

35 y in EAE via pleiotropic pathways, but it is dispensable during early lesion formation and the onset

36 IL-33 signaling was dispensable during effector/challenge phase.

37 sory factor Fcho1 at the plasma membrane, is dispensable during embryogenesis, enabling us to define

38 erization and recruits cellular adaptors, is dispensable during ER-to-cytosol transport of SV40, this

39 oing positive selection in humans can become dispensable during propagation in mice.

40 re potassium channel (K2P) subunits, largely dispensable early in life, are necessary for terminating

41 gene transactivation-associated events, yet dispensable for 53BP1-dependent DSB repair regulation.

42 ontrast, TLR13 and its chaperone UNC-93B are dispensable for a potent cytokine response of blood mono

43 MMR-nicking complex Pms2/Mlh1 is apparently dispensable for A-T mutagenesis.

44 pKM101 OMCC cap and extended pilus also are dispensable for activation of a Pseudomonas aeruginosa t

45 In vivo B cells were dispensable for activation of naive 1-DER T cells but ne

46 2p, a non-essential protein that is normally dispensable for actomyosin ring assembly and contraction

47 on, EP3 receptors on serotonergic cells were dispensable for acute nociceptive behaviors and for aver

48 IL-4-responsive T helper cells are dispensable for acute OVA-induced airway disease but cru

49 we show that endogenous KLF4 and Krox20 are dispensable for adipogenesis in culture and for brown ad

50 While Bif-1 is dispensable for adipose tissue development, its deficien

51 level of beta-Catenin in AJs and is in fact dispensable for AJ formation in vivo Nonetheless, phosph

52 ired for spermatogenesis, but was considered dispensable for all other cell types.

53 In contrast, TNF was dispensable for allergic airway disease in a protease-me

54 aptorKO), we showed that mTORC1 signaling is dispensable for alpha cell development, but essential fo

55 at although essential for symbiosis, D14L is dispensable for AMF-induced root architectural modulatio

56 We provide evidence that Bcl7b is dispensable for animal survival as well as behavioral pl

57 e RA-triggered transcriptional activation is dispensable for APL eradication.

58 , and regions upstream of 70 bp to 3 kbp are dispensable for AT2R induction.

59 Here, we demonstrate that ATMIN is dispensable for ATM activation in hypoxia and in contras

60 We show that Atg8s are dispensable for autophagosome formation and selective en

61 In contrast to canonical bEBPs that are dispensable for bacterial growth, Rrp2 is essential for

62 Here we show that AR is dispensable for basal cell maintenance, but is cell-auto

63 our results demonstrate that mouse TrpC3 is dispensable for beta-alanine-induced acute itch.

64 uitment, whereas the C-terminal interface is dispensable for binding Est1 in vitro yet is nevertheles

65 g the TGF-beta type I receptor (TbetaRI) but dispensable for binding the other receptor required for

66 Thus, pili are dispensable for biofilm development in this cyanobacteri

67 ding the DiCre recombinase into genomic loci dispensable for blood stage development.

68 n of the mineralization-related genes, it is dispensable for BMP2 to induce the protein anabolism sig

69 adipocytes, we found unexpectedly that GR is dispensable for brown adipose tissue development in mice

70 The SH3 domain of Boi2, which is dispensable for bud growth and targets Boi2 to the site

71 inding that both the DEP and PDZ domains are dispensable for canonical signaling only in membrane-tet

72 The C-terminal domain (CTD) is deemed dispensable for capsid assembly although it is essential

73 We found that Neat1 is dispensable for cell cycle arrest and apoptosis in respo

74 they are essential for HIV-1 infection, but dispensable for cell survival.

75 er study, we demonstrated that Hif-2alpha is dispensable for cell-autonomous HSC maintenance, both un

76 that are required for HIV infection yet are dispensable for cellular proliferation and viability.

77 host factors required for HIV infection but dispensable for cellular survival.

78 The ARTEMIS C terminus is dispensable for cellular V(D)J recombination and in vitr

79 at the heterotrimeric ciliary kinesin may be dispensable for certain aspects of transport in speciali

80 nase 6 (GRK6) is crucial for haptotactic but dispensable for chemotactic CCL21 gradient sensing in vi

81 In adult duodenum, Nkx2.2 becomes dispensable for cholecystokinin and secretin production.

82 HeDNA is required for DNA methylation but is dispensable for chromatin interaction, which is governed

83 ential to initiate cilia formation, they are dispensable for cilia maturation and maintenance.

84 conformation at CAs, its kinase activity is dispensable for ciliogenesis and ciliary function reveal

85 e interaction of Ent5 with other adaptors is dispensable for coat behavior but not cargo traffic.

86 ly show that floor plate-derived netrin-1 is dispensable for commissural neuron axon guidance to the

87 We show that the mu-homology domain is dispensable for COPI function in the early secretory pat

88 indicating that the transmembrane domain is dispensable for CpaA secretion and likely functions to r

89 eas Atg genes involved in macroautophagy are dispensable for crinophagy.

90 ruits BRD2 to co-bound sites whereas BRD2 is dispensable for CTCF occupancy.

91 rast, the recognition of apoptotic cells was dispensable for cytokine-dependent induction of pattern

92 TGFbeta is required for D-ECM production but dispensable for D-ECM-induced naive fibroblast-to-CAF ac

93 eloproliferative leukemia virus liganding is dispensable for definitive thrombopoiesis, establishing

94 ate protein aggregates showing that ClpXP is dispensable for degradation of unfolded proteins in S. a

95 mTOR was dispensable for dendritic cell (DC) homeostasis in secon

96 The nuclease domain is dispensable for DNA binding but residues lining the acti

97 during DNA replication but is thought to be dispensable for DNA end resection.

98 Here, we show that AIM2 is dispensable for DNA-mediated inflammasome activation in

99 ineage identity of group 1 ILCs, while being dispensable for early ILC development and homeostasis of

100 ever, trophoblast-specific GATA3 function is dispensable for early mammalian development.

101 results show that SCF and KIT signaling are dispensable for early mast cell development.

102 ells with enhanced effector functions but is dispensable for education.

103 We show that zygotic expression of gdf3 is dispensable for embryonic development, while maternally

104 nesis of filiform papillae but appears to be dispensable for embryonic hair follicle development.

105 find that Bicoid transcriptional activity is dispensable for embryonic viability in the first hour af

106 the first dsRNA-binding motif of Loqs-PD is dispensable for enhancing cleavage of optimal substrates

107 biogenesis, we provide evidence that LDs are dispensable for ERAD in mammalian cells.

108 Although FRS adapters are dispensable for ERK-1/2 activation, they are required fo

109 SET)); surprisingly, the Set1A SET domain is dispensable for ESC proliferation and self-renewal.

110 We reveal that HSP90beta, although dispensable for expression of HNF4A mRNA, directly inter

111 ction model, we show the T. brucei BBSome is dispensable for flagellar assembly, motility, bulk endoc

112 We also found that CcoQ is dispensable for forming an active CcoNOP subcomplex in m

113 The N-domain of the Qb-SNARE was completely dispensable for fusion.

114 aluable in vivo data showing that miR-155 is dispensable for gammaherpesvirus latency but that it is

115 elium and mesenchyme and find that, although dispensable for gastrointestinal epithelial development

116 quired for discriminative fear, but both are dispensable for generalized fear at high US intensities.

117 +) T cell responses, Tcf1 long isoforms were dispensable for generating cytotoxic CD8(+) effector T c

118 (ii) the RNase H2 enzymes RnhB and RnhD are dispensable for growth and (iii) RnhB and RnhA collabora

119 TlgB(Tlg2) is dispensable for growth but becomes essential if the earl

120 und that while the class II myosin (myoB) is dispensable for growth, the class V myosin (myoE) is req

121 d fibroblasts, we found that Ras GTPases are dispensable for growth-factor-stimulated macropinocytosi

122 ith the suggestion that the stripe of Dpp is dispensable for growth.

123 d that the CD1- or CD3-specific regions were dispensable for hair bundle integrity and labeling of ha

124 rmore, we found that STAT3 in hepatocytes is dispensable for HCC formation when mammalian sterile 20-

125 nally for gata2 expression in the DA, but is dispensable for HE specification after hemangioblasts ha

126 ontains an N-terminal domain (p150N) that is dispensable for histone deposition but promotes the loca

127 Here, we show that Dnmt3a and Dnmt3b are dispensable for homeostasis of the murine epidermis.

128 Although dispensable for homeostatic Th17 cell development, JunB

129 53BP1 and Ku70/80 complex, whereas TRADD is dispensable for homologous recombination (HR) repair.

130 ponses upon NS4B-P38G vaccination and yet is dispensable for host protection and recall T cell respon

131 RagA was also dispensable for HSC function under nutritional stress co

132 the CA CTD has been suggested to be largely dispensable for human T-cell leukemia virus type 1 (HTLV

133 he three disulfide bridges in IL-12alpha are dispensable for IL-12 secretion, stability, and biologic

134 on channel vanilloid subtype 1 channels were dispensable for IL-31-induced neuronal sprouting.

135 gamma signaling in T cells, although largely dispensable for IL-4 induction, is critical for IL-33-dr

136 Although Myc was found to be dispensable for in vivo HB initiation, it was necessary

137 g Sma1, a phospholipase D-associated protein dispensable for initiation of PSM assembly and PSM curva

138 uction, activation of monocytes via P2X7 was dispensable for iNKT-induced IL-1beta secretion, and pot

139 eneca valley virus (SVV), a picornavirus, is dispensable for IRES activity, while the IIId2 sub-domai

140 for RNR cofactor formation but appears to be dispensable for iron loading.

141 esis, we found that GTP binding of K-Ras was dispensable for its packaging within extracellular nanov

142 7-to-Ala knockin (p27T187A KI), it was found dispensable for Kras(G12D)-induced lung tumorigenesis bu

143 c Cre-deletion of HIFs that myeloid HIFs are dispensable for leukocyte migration into the inflamed ey

144 FX is dispensable for liver transduction in mice lacking IgM a

145 This study shows that lipogenesis is dispensable for liver tumorigenesis in mice treated with

146 formation and DNA elimination, whereas it is dispensable for local heterochromatin assembly.

147 id specification, unexpectedly appears to be dispensable for lung specification.

148 Interestingly, Brd4 is dispensable for maintaining cell identity genes in diffe

149 monstrate that while EC-derived jagged-2 was dispensable for maintaining the capacity of HSPCs to rep

150 found that the K63-Ub DUB activity, although dispensable for maintaining the integrity of the macromo

151 Surprisingly, they appear to be dispensable for mammalian proximal tubule (PT) function.

152 r data demonstrate that VPS52 and VPS54 were dispensable for mature virion (MV) production but were r

153 FANCA and FANCG are dispensable for maximal in vitro ubiquitination.

154 ulated by upstream checkpoint signals and is dispensable for MCC assembly.

155 However, MAVS is dispensable for memory T cell development and host prote

156 entary approaches demonstrating that MLL1 is dispensable for MLL-fusion-mediated leukemogenesis.

157 ndent animal models, that endogenous MLL1 is dispensable for MLL-rearranged leukemia.

158 Here, we show that Sall4 is dispensable for mouse ESC pluripotency.

159 Together, this suggests that PAK4 is dispensable for mouse pancreas development.

160 -derived MKs, HDAC6 and CTTN are shown to be dispensable for mouse PPF in vitro and platelet producti

161 We focus on PARP3 as it is dispensable for murine viability and has druggable catal

162 We conclude that HIF1alpha and HIF2alpha are dispensable for muscle stem cell function under normoxia

163 id cells during inflammation and hypoxia are dispensable for myeloid cell tissue trafficking.

164 Eosinophils were dispensable for myocarditis induction but were required

165 neurons, suggesting that this transporter is dispensable for neural differentiation and short-term ma

166 We show that UNC-45A is dispensable for neuron survival but required for neurite

167 Although dispensable for noncrossover formation, a functional pro

168 ice, in which miR-10b is shown to be largely dispensable for normal development but critical to tumor

169 RAD52, a gene dispensable for normal development in mice, was among th

170 the tyrosine phosphatase activity of Eya is dispensable for normal Eya function in eye formation, we

171 ct pathway of the plasma clotting cascade is dispensable for normal hemostasis, but contributes to th

172 d type and demonstrates that sperm cells are dispensable for normal pollen tube development.

173 eff2 is specifically upregulated in OLs, but dispensable for OL differentiation and maturation.

174 pe the temporal ERK activity profile but are dispensable for oscillations.

175 hened extracellular domain, a region that is dispensable for Patched1-Smoothened coupling.

176 b-mediated Ser2 phosphorylation of Pol II is dispensable for pause release.

177 9 axis, CD4(+) and CD8(+) T cells, which are dispensable for PDA progression in hosts with an intact

178 ratumoral Treg stability and function but is dispensable for peripheral immune tolerance.

179 onstrate that dKDM4A demethylase activity is dispensable for PEV.

180 Here we report that PAXX is dispensable for physiological NHEJ in otherwise wild-typ

181 In contrast, ATPase activity of TDRD9 is dispensable for piRNA biogenesis but is essential for tr

182 n contrast, polycomb repressive complex 2 is dispensable for pluripotency when human embryonic stem c

183 (iii) The ICP0 C terminus is dispensable for PML I degradation.

184 We demonstrate that E2F is dispensable for proliferation of muscle progenitor cells

185 inhibition and stimulation of elongation, is dispensable for promoter-proximal pausing.

186 tion in vivo, natural killer (NK) cells were dispensable for protective immunity.

187 ecular explanation as to why the N domain is dispensable for protein disaggregation when Hsp70/40 is

188 Although the N domain is dispensable for protein disaggregation, it is sensitive

189 first 13 and 66 TP residues were shown to be dispensable for protein priming and pgRNA binding, respe

190 We propose that BRCA2 is dispensable for RAD51-mediated fork reversal, but assemb

191 Whereas TGF-beta signaling is dispensable for rapid fibrillogenesis, stable interactio

192 gineered into intracellular regions that are dispensable for regulation.

193 Previous studies suggested that UL21 is dispensable for replication in cell cultures, but a rece

194 Additionally, Mre11 endonuclease activity is dispensable for resection in G1.

195 interaction between CtIP and BRCA1, although dispensable for resection of endonuclease-generated DSB

196 Wdr70 is dispensable for resection upon Crb2(53BP1) loss, or when

197 ired in both fusion partners, whereas it was dispensable for SC proliferation and differentiation.

198 n recruitment; rather, arrestin was entirely dispensable for scavenging of either chemokine.

199 in human breast cancer cells, SDHAF2/SDH5 is dispensable for SDHA flavination.

200 Unexpectedly, morc-1 is dispensable for siRNA inheritance but is required for ta

201 , and recent studies have shown that CCR5 is dispensable for SIV infection of SM in vivo and that blo

202 Smad4 is required for EMT but dispensable for Sox4 induction by TGF-beta.

203 in vivo experiments showed that LEDGF/p75 is dispensable for steady-state hematopoiesis but essential

204 TGF-beta signals were dispensable for steady-state Treg cell homeostasis and f

205 umefaciens VirB/VirD4 systems are completely dispensable for substrate transfer, but required for for

206 receptor (GR) expression in immune cells was dispensable for successful therapy of allergic airway in

207 P, whereas the endothelial S1P1 receptor was dispensable for survival despite its importance for main

208 al C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate starvation and is

209 physiology and redox poise, an axis that is dispensable for survival under normoxic conditions but i

210 the pumping function of its heart is acutely dispensable for survival, Drosophila represents a unique

211 Surprisingly, MIIC targeting is dispensable for T cell-dependent immunity.

212 LRRC8A-dependent VRAC activity is dispensable for T-cell development and function.

213 otif in Bcl11b protein, which by contrast is dispensable for T-lineage commitment.

214 ial for cleavage of MKK3, MKK4, and MKK6 but dispensable for targeting of MEK1, MEK2, and NLRP1B.

215 Unlike Rad26, which becomes completely dispensable for TCR in cells lacking the TCR repressor S

216 Although PKC- is dispensable for TCR-independent Treg proliferation per s

217 41, a target of the vacuolar kinase Yck3, is dispensable for tethering and fusion but can affect teth

218 However, S6K2 was dispensable for Th17 differentiation in IMDM.

219 These results suggest that S6K2 is dispensable for Th17-driven autoimmunity and highlight h

220 We demonstrate that MHCII is dispensable for the B cell phenotype of SPPL2a(-/-) mice

221 Consistent with that, Rab5 is dispensable for the Ccz1-Mon1-dependent recruitment of R

222 pproaches, we found that capture of IL-2 was dispensable for the control of CD4(+) T cells but was im

223 e found that the phosphorylation of Cav-1 is dispensable for the control of T-cell fate by using a no

224 Our data show that (i) PI(3)P and PI(4)P are dispensable for the disassembly and activation of (phago

225 urther show that functional RRM1 or RRM2 are dispensable for the exclusive protein nuclear localizati

226 preformed chromatin compartments and may be dispensable for the formation of higher order chromatin

227 esting that these cells or their subsets are dispensable for the induction of AAD in IL-15-deficient

228 P kinetochore detachment events, while being dispensable for the initial biorientation and movement o

229 ed studies revealed that the synergy site is dispensable for the initial contact of alpha5beta1 with

230 inding and catalytic activities of AGO2 were dispensable for the interaction but required for the rec

231 CBU0077 was dispensable for the intracellular replication of Coxiell

232 8(-) thymocyte development, we show CXCR4 is dispensable for the maintenance and intrathymic position

233 showed that RNase 7 ribonuclease activity is dispensable for the observed regulatory effect.

234 B and T cells were dispensable for the onset of swelling but required for r

235 studies indicate that Leishmania SepSecS is dispensable for the parasite survival.

236 onstrate that beta-cell GPR119 expression is dispensable for the physiological control of insulin sec

237 onic eminence (MGE)-derived neurons, but are dispensable for the survival of early telencephalic prec

238 terminal low-affinity CNB domain (CNB-A) was dispensable for the translocation to the membrane, it wa

239 ress-induced nuclear accumulation of Hog1 is dispensable for the virulence of a major human fungal pa

240 f beta cell-autoreactive CD8 T cells but was dispensable for their activation in pancreatic lymph nod

241 y, G protein-dependent beta2AR signaling was dispensable for these effects, whereas beta-arrestin2-bi

242 Intriguingly, EDEM mannosidase activity was dispensable for these protective effects.

243 , the classical esterase activity of AChE is dispensable for this activity.

244 morphogenesis and direct reprogramming, was dispensable for this process.

245 we find that Arp2/3-dependent pseudopods are dispensable for three-dimensional locomotion, their elim

246 Here, we report that, despite being dispensable for thymocyte clonal deletion, RasGRP1 is cr

247 ce, we here demonstrate that although NIK is dispensable for thymocyte development, it has a cell-int

248 We show that coronin 1 is dispensable for thymocyte survival and development, egre

249 oreductase activity of Mia40 is surprisingly dispensable for Tim17 oxidation.

250 97 of FAK promotes dense NA formation but is dispensable for transient NA stabilization and leading e

251 , surprisingly, this conserved methionine is dispensable for transport of the physiological manganese

252 NF-kappaB was, however, dispensable for Treg development.

253 However, intrinsic MAVS signaling was dispensable for Treg proliferation and suppressive capac

254 ity in vivo, our results indicate that it is dispensable for tRNase activity in vitro.

255 a receptor activin receptor-like kinase 5 is dispensable for trypsin and PAR2 activating peptide (PAR

256 ns in the gK locus, but UL21 was shown to be dispensable for UL20(Syn) and UL24(Syn) To test whether

257 terestingly, we found that both proteins are dispensable for UQ biosynthesis under anaerobiosis, even

258 he XRCC4-like-factor (XLF) C-NHEJ protein is dispensable for V(D)J recombination in normal cells, but

259 uggest that core interaction with betaarr is dispensable for V2R endocytosis and ERK activation and t

260 nteractions involving either eS7 or uS17, is dispensable for viability.

261 o virions with high efficiency despite being dispensable for virion assembly.

262 Exg8 is largely dispensable for virulence in vivo, in contrast to Eng1.

263 rally encoded IFN antagonist and that NSs is dispensable for virus replication.

264 s for ER to the mitochondria trafficking are dispensable for vMIA trafficking to OMM.

265 BEAF-32 is dispensable for Warts feedback, indicating that BEAF-32

266 Consistently, DEX accelerates, but is dispensable for, adipogenesis in culture.

267 ediated activation of GR accelerates, but is dispensable for, adipogenesis.

268 cating that DEX-bound GR accelerates, but is dispensable for, adipogenesis.

269 2+) signals, and it greatly promotes, but is dispensable for, the activation of CaMKII and LTP.

270 nd replication rely on a limited set of host-dispensable genes and suggest that these pathways can be

271 The epoxidase gene was dispensable in a nematode-infective juvenile recovery as

272 genome editing and demonstrate that KRAS is dispensable in a subset of human and mouse PDAC cells.

273 cell model where the autophagy gene ATG5 is dispensable in A549 cells in vitro, yet promotes tumorig

274 etermine that HIV-1 Nef accessory protein is dispensable in BAFF upregulation as a nef-deleted HIV-1

275 Surprisingly, Twist1 is dispensable in endothelial cells but required for specif

276 entered network identified 46 genes that are dispensable in estrogen-dependent MCF7 cells, but are se

277 Bcl-2 is dispensable in homeostasis and, although involved in pro

278 dered C-terminal tails that are functionally dispensable in isolation but are phosphorylated in respo

279 ial persistence in immune-competent mice are dispensable in mice with predisposing conditions such as

280 These results suggest that telomeres are dispensable in terminally differentiated neurons and pro

281 lar stomatitis virus, or Vaccinia virus, but dispensable in the case of mouse cytomegalovirus.

282 uestions about what is essential and what is dispensable in the compendium of Fe-S cluster protein fu

283 o maintain organismal Mg(2+) balance, but is dispensable in the kidney.

284 reas the other leukemia-induced lncRNAs were dispensable in the normal setting.

285 us viruslike particles, and the viral RNA is dispensable in this process.

286 b GTPase Ypt7 is essential in vivo but often dispensable in vitro.

287 However, this study identified the likely dispensable nature of a Delta12-desturase activity in ou

288 ative enzyme pyruvate carboxylase (TgPyC) is dispensable not only in glycolysis-competent but also in

289 of the ribosome into subunits being somewhat dispensable, or whether their main function is to cataly

290 ivision, but in this background the normally dispensable PBP 3 becomes essential.

291 in circulating leukocytes to demonstrate the dispensable role of HIFs in myeloid cell migration into

292 bacterial chemotaxis and motility range from dispensable to crucial for host colonization.

293 Although alphabetaT cells were dispensable to outcome in PDA, they became indispensable

294 f cells homeostasis but, unexpectedly, it is dispensable to prevent development of severe spontaneous

295 eliant upon lipoamide-utilizing enzymes, but dispensable when this reliance is decreased.

296 gests that nuclear and kinesin functions are dispensable, whereas binding to CYK-4 is essential, for

297 the actin-binding domains of nesprin 1 were dispensable, whereas nesprin 1alpha2, which lacks actin-

298 ce, we found that monocyte-derived APCs were dispensable, while classical dendritic cells (cDCs) were

299 Adaptive immune cells and CCR2 are dispensable, while CXCR2 is necessary for Brucella-induc

300 mutant, the presence of Sty1 was completely dispensable, with all stress defects of Sty1-deficient c