ライフサイエンスコーパス: dissemination

1 carcinoma cells and drives their metastatic dissemination.

2 quent and range from superficial to systemic dissemination.

3 contrast, the controls showed widespread TB dissemination.

4 tion, progression, and widespread metastatic dissemination.

5 l transition is a common event during tumour dissemination.

6 crophages to tumor cells promotes tumor cell dissemination.

7 ic analyses with minimal risk of extraocular dissemination.

8 er expression was associated with metastatic dissemination.

9 when silenced, suppresses invasion and tumor dissemination.

10 at the invasive front, accompany cancer cell dissemination.

11 apeutic intervention during early metastatic dissemination.

12 hibit chemotherapy resistance and metastatic dissemination.

13 ation of the gut lumen and prevents systemic dissemination.

14 asmic transfer correlated with melanoma cell dissemination.

15 ement, especially in domains crucial for the dissemination.

16 enses against cryptococcal infection and CNS dissemination.

17 eins capable of inhibiting fungal growth and dissemination.

18 n of EMT-associated genes during blood-borne dissemination.

19 l invasiveness and, consequently, metastatic dissemination.

20 viscera, suggesting that adenosine promotes dissemination.

21 actor activation is rate-limiting for tumour dissemination.

22 findings provide insights into breast cancer dissemination.

23 ate granulomatous inflammation and bacterial dissemination.

24 reducing pathogen transmission and systemic dissemination.

25 exciting development with potential for wide dissemination.

26 aracterized by TP53 mutations and peritoneal dissemination.

27 gnosis, may cause anaphylactic reactions and dissemination.

28 s was accompanied by increased fungal kidney dissemination.

29 c transfer mechanisms in cases of accidental dissemination.

30 CR10 or CD103 was associated with widespread dissemination.

31 NB and implicate the NPY/Y5R axis in disease dissemination.

32 nfection is important for virus survival and dissemination.

33 logy, and increased mycobacterial burden and dissemination.

34 cells, facilitating immune evasion and virus dissemination.

35 in vitro, preventing transcellular bacteria dissemination.

36 ikely due to their reduction in the systemic dissemination.

37 facilitate human colonization, invasion, and dissemination.

38 ponding to increased tumor cell motility and dissemination.

39 innate lymphoid cells, and limited bacterial dissemination.

40 days was associated with Candida bloodstream dissemination.

41 reptococcus pyogenes and prevented bacterial dissemination.

42 s expensive, slow, and may under-diagnose TB dissemination.

43 vivo hemostasis, yet is critical for in vivo dissemination.

44 ys, all patients survived and none developed dissemination.

45 tor (VEGF) therapy-induced glioma growth and dissemination.

46 (ECM) is a critical enabler of breast cancer dissemination.

47 rentiation, proliferation, invasiveness, and dissemination.

48 ord of pathogen diversification and repeated dissemination across the body.

49 To successfully limit pathogen dissemination, an immunological link between the entry t

50 Furthermore, bacterial dissemination analysis demonstrated that predatory bacte

51 incubation periods, may enable unrecognized dissemination and adaptation to other gallinaceous speci

52 ate that KSHV miRNAs may be critical for the dissemination and angiogenesis of KSHV-induced malignant

53 of skin presentation for >/=14 days prevents dissemination and Candida-related mortality.

54 Dissemination and cardiovascular involvement are common,

55 standing of how the immune system limits NiV dissemination and contributes to ALI and inform efforts

56 In others, cell death enhances virus dissemination and contributes to tissue injury, exacerba

57 y treatment is associated with high rates of dissemination and death.

58 xpression of LMO1 also promoted hematogenous dissemination and distant metastasis, which was linked t

59 gin, and is crucial to metastatic tumor cell dissemination and drug resistance.

60 y assays and provides a platform for review, dissemination and extension of the strategies it employs

61 experiment instructions to set the stage for dissemination and further development in education and r

62 HIKV strain displayed a capacity for earlier dissemination and greater pathogenicity than the parenta

63 to activate gliding motility to power tissue dissemination and host cell invasion and egress.

64 ve role and is required to prevent bacterial dissemination and host morbidity by controlling effector

65 me scheduling remains a major limitation for dissemination and implementation of robust and large mul

66 Efforts to increase the dissemination and implementation of SCD treatment guidel

67 new therapeutic approaches to decrease viral dissemination and improve immune responses against HIV-1

68 apy has significant limitations due to rapid dissemination and inactivation of the therapeutics at th

69 other virulence genes that enhance pathogen dissemination and infection are significantly up-regulat

70 her morbidity and are more prone to pathogen dissemination and intestinal and systemic inflammation d

71 yses transparent for critical evaluation and dissemination and is therefore a significant improvement

72 foci and blood faster, and reducing risks of dissemination and metastatic infection.

73 e, the biological programs that underlie the dissemination and metastatic outgrowth of cancer cells a

74 der to study how tetherin affects retroviral dissemination and on which cell types its expression is

75 Future studies should focus on dissemination and optimizing therapist support methods t

76 R1 may represent a novel strategy to prevent dissemination and overt relapse in multiple myeloma.

77 rect cell-to-cell transmission to retroviral dissemination and pathogenesis are unknown.

78 n and cell-free virions during in vivo viral dissemination and pathogenesis, we developed mice carryi

79 n was largely responsible for enhanced viral dissemination and pathogenicity, although these effects

80 findings reveal viral determinants of CHIKV dissemination and pathogenicity, their further study sho

81 iggers biological changes that promote viral dissemination and persistence.

82 t with this observation, the increase in GBS dissemination and preterm births observed in MCPT4-defic

83 t the protective effect of MCPT4 against GBS dissemination and preterm labor can be attributed in par

84 then risk of KSHV infection but enhance KSHV dissemination and progression to KS if infection occurs.

85 a number of virulence factors essential for dissemination and survival of C. neoformans in a host en

86 thus may potentially be responsible for its dissemination and survival.

87 ne defenses are critical for controlling GBS dissemination and systemic infection.

88 rial intestinal colonization, translocation, dissemination and systemic infections.

89 yet unidentified cell type was essential for dissemination and systemic spread of L. monocytogenes In

90 ential spreaders" for maximizing information dissemination and targeted interventions in regulatory n

91 rs do not present a barrier against pathogen dissemination and that non-neighbouring countries are ep

92 Importantly, infection, dissemination and transmission rates in mosquitoes are o

93 infection associated with delayed bacterial dissemination and upregulated TNF production in the lung

94 es enabled bacterial transfer and subsequent dissemination, and interrupting this transfer so as to p

95 Survival, bacterial dissemination, and intestinal and systemic pathology of

96 ller (NK) cells in the control of metastatic dissemination, and present potential therapeutic approac

97 the viral egress mechanisms for cell-to-cell dissemination, and revealed an absence of actin tails in

98 ntibiotic resistance genes, their subsequent dissemination, and the ongoing colonization of diverse e

99 mmatory cytokine levels, inhibited bacterial dissemination, and ultimately conferred a significant su

100 atic reviews with frequent updating and open dissemination are now needed both for appraisal of the e

101 s that are suggested to underlie cancer cell dissemination are specific to the metastatic process, as

102 igin of ST59 and its international routes of dissemination are unclear and disputed in the literature

103 ckades of JNK and MMP1 suppressed metastatic dissemination associated with S100A4 elevation, defining

104 udy reveal a novel mechanism of picornaviral dissemination, but also it sheds light on new therapeuti

105 ning might allow for greater scalability and dissemination, but with a potential reduction in CC dept

106 It specifically inhibited the metastatic dissemination capability of colon cancer cells HT29, inc

107 d bioassays, including drug screening, tumor dissemination, cell co-culture, and tumor invasion.

108 gest that skeletal sites prone to tumor cell dissemination contain less-mature HA (i.e., smaller, les

109 he stepwise pattern of virus replication and dissemination described here suggests that vaccine-elici

110 for genome annotation, analysis, storage and dissemination designed to facilitate the access of genom

111 ized by high levels of virus replication and dissemination, dysregulated immune responses, extensive

112 Greater resources and dissemination efforts are needed to increase the availab

113 rs; (ii) cancer metastasis could be an early dissemination event that could occur during malignant do

114 the implant model, where there was decreased dissemination from an hysA mutant biofilm infection comp

115 ection led to weight loss and L. interrogans dissemination from blood to urine, and spirochetes were

116 plasmid is essential for Chlamydia muridarum dissemination from the genital tract to the gastrointest

117 these mutations in the enhancement of viral dissemination from the inoculation site and in disease s

118 ur-infiltrated mMDSCs facilitate tumour cell dissemination from the primary site by inducing EMT/CSC

119 st that the E2 K200R mutation enhances viral dissemination from the site of inoculation independently

120 nvironmental manipulation was present in all dissemination grants but was rarely used elsewhere, and

121 res; it plays roles in protection, adhesion, dissemination, host targeting in pathogens and germinati

122 iR-139-5p overexpression enhanced peritoneal dissemination in a mouse model.

123 o facilitate TKI resistance, EMT, and cancer dissemination in a subset of lung adenocarcinoma cells.

124 mal transition (EMT) and enhanced tumor cell dissemination in adjacent brain parenchyma after ionizin

125 erves and thus induce ready-to-use routes of dissemination in early carcinogenesis.

126 uman cell lines and virulence and multiorgan dissemination in mice.

127 ubverts mitophagy machinery to support viral dissemination in released EMVs.IMPORTANCE Coxsackievirus

128 modifications to the MRI criteria to define dissemination in space (DIS) and time (DIT) for the diag

129 mptomatic lesions can be used to demonstrate dissemination in space or time in patients with supraten

130 yndrome and clinical or MRI demonstration of dissemination in space, the presence of CSF-specific oli

131 tent with the 2010 McDonald MRI criteria for dissemination in space.

132 cortical lesions can be used to demonstrate dissemination in space.

133 colorectal cancer cells promoted tumor cell dissemination in the bone marrow and enhanced osteolytic

134 how that LOX supports colorectal cancer cell dissemination in the bone marrow and they reveal a novel

135 g that programmed cell death may limit viral dissemination in the brain and may constrain virus-assoc

136 ed syndrome, define what is needed to fulfil dissemination in time and space of lesions in the CNS, a

137 HMMR upregulation was not required for dissemination in vivo, but enhanced ECM-mediated signali

138 1 expression results in increased metastatic dissemination in vivo.

139 lammatory niche to aid their replication and dissemination in vivo.

140 afficking of an Eph receptor to drive tumour dissemination in vivo.

141 on sequence resulted in increased metastatic dissemination in xenograft or syngeneic tumor models in

142 ity and is associated with several routes of dissemination including lymphatic and hematogenous.

143 In each case suggestive of a dissemination into the central nervous system, MRI of th

144 We document progressive EBOV dissemination into the eyes, brain and testes through va

145 A key step in dissemination is bacterial interaction with endothelia l

146 Hematogenous dissemination is important for infection by the pathogen

147 ch promote therapy resistance and metastatic dissemination is the key to successful treatment.

148 trations were identified, resulting in rapid dissemination (<2wk) of health alerts to local health de

149 ic cancer and melanoma models, indicate that dissemination might occur during the early stages of tum

150 Collectively, these data reveal a late-dissemination model of metastasis in two CRC patients an

151 ly diagnosed with the presence of peritoneal dissemination (n = 22) and/or positive peritoneal cytolo

152 ly diagnosed with the presence of peritoneal dissemination (n = 22) and/or positive peritoneal cytolo

153 Thus, in addition to bacterial dissemination, necrotic cells provide first a niche for

154 As an early metastatic event, cancer cell dissemination occurs through different migration program

155 Since this site is well-perfused, a rapid dissemination of "fitter" clones may be anticipated.

156 In virtual case studies, we found that the dissemination of activated T cells among multiple metast

157 The rapid development and dissemination of ALPPS with the availability of many var

158 -to-amoeboid transition (CAT), promoting the dissemination of amoeboid-moving single cells from colle

159 are notorious for their contribution to the dissemination of antibiotic resistance and the emergence

160 will facilitate the monitoring of the global dissemination of antimicrobial-resistant N. gonorrhoeae

161 HCAs) remains limited despite the widespread dissemination of automated external defibrillators (AEDs

162 tective as wild-type CD4 T cells against the dissemination of bacteria and mortality.

163 was more efficient in reducing the systemic dissemination of bacterial cells.

164 t a potential trade-off in efforts for broad dissemination of basic CPR skills; VO training might all

165 ominant factor driving tissue damage and the dissemination of both organisms to the bloodstream durin

166 ncer by promoting proliferation and vascular dissemination of cancer cells and the accumulation of in

167 he complex clonal dynamics that underlie the dissemination of cancer cells to distant sites.

168 s cellular processes required for peritoneal dissemination of cancer cells, one of the predominant fa

169 sport may not effectively prevent metastatic dissemination of cancer cells.

170 tion to promote proliferation, survival, and dissemination of cancer cells.

171 y event that is involved in the invasion and dissemination of cancer cells.

172 The dissemination of carbapenem resistance in Escherichia co

173 The widespread dissemination of carbapenem-resistant Acinetobacter spp.

174 ecognized for the last 2 decades, but global dissemination of carbapenemase-producing Enterobacteriac

175 ng in joint-associated tissues and prevented dissemination of CHIKV and RRV at early time points.

176 taminated environments.IMPORTANCE The facile dissemination of chronic wasting disease within captive

177 markedly from 2013 to 2015 concomitant with dissemination of clinical guidelines endorsing a minimal

178 al symptoms and signs, alongside evidence of dissemination of CNS lesions in space and time.

179 ence to support the efficacy of online-based dissemination of cognitive behavioral therapies, which h

180 macologic inhibition of LOX activity blocked dissemination of colorectal cancer cells in the bone mar

181 The dissemination of computer-based cognitive behavioral the

182 /responsibilities, community engagement, and dissemination of disaster research results.

183 his work will serve as a springboard for the dissemination of diverse blood-based diagnostics.

184 of concern regarding risks arising from the dissemination of E. coli that may remain viable in waste

185 t-delivered CBT-I may have a key role in the dissemination of effective behavioral treatments for ins

186 evelopment of chemoresistance and peritoneal dissemination of EOC cells are the major reasons for low

187 ve been developed to address barriers to the dissemination of evidence-based psychological treatments

188 lorfenicol has resulted in the emergence and dissemination of florfenicol resistance genes (FRGs, inc

189 gesting that clonal expansion is involved in dissemination of FQ(R) C. coli but not C. jejuni.

190 ptation of life on our planet and imply that dissemination of genes encoding diverse adaptive functio

191 be tractable is by studying the dynamics and dissemination of genes for antibiotic resistance and the

192 Horizontal gene transfer permits rapid dissemination of genetic elements between individuals in

193 gy, provide a useful database for the public dissemination of GWAS results, and provide a method for

194 inter-patient transmission and intra-patient dissemination of highly antibiotic-resistant pathogens.

195 nly into the role of DCs in transmission and dissemination of HIV-1 but also more broadly into mechan

196 Dissemination of HIV-1 throughout lymphoid tissues leads

197 ted neurovirulence and atypical lymphotropic dissemination of HSV-1 following ocular infection.

198 Dissemination of infection beyond the lungs was also det

199 s its edema factor modulates progression and dissemination of infection.

200 Food and Drug Administration approaches to dissemination of information about appropriate use with

201 Sequential dissemination of information from one enzyme to another

202 the Internet has exploded, allowing for easy dissemination of information.

203 Particularly concerning is the widespread dissemination of Klebsiella pneumoniae carbapenemase (KP

204 earch programs, and how it may influence the dissemination of knowledge to physicians and scientists

205 ormulate recommendations that facilitate the dissemination of knowledge within and outside the field

206 pidemic was primarily mediated by the clonal dissemination of Kpn ST258.

207 the endogenous gene, enhanced the metastatic dissemination of lung adenocarcinoma cells.

208 d in 2011 to standardize data submission and dissemination of mass spectrometry proteomics data world

209 obtaining material at a scale useful to the dissemination of mass standards was measured by instrume

210 sult is a new paradigm that thinks about the dissemination of medical knowledge and discovery as ongo

211 lds should be considered to facilitate safer dissemination of MIPD.

212 art of the epidemic was driven by horizontal dissemination of mobile genetic elements carrying blaKPC

213 by stromal-derived CXCL12, thereby enabling dissemination of multiple myeloma PCs.

214 ts represent a strategic contact node in the dissemination of multiple pathogens.

215 Intercontinental dissemination of multiresistant shigella strains, facili

216 4 effector functions that mediate metastatic dissemination of mutant Ras-induced tumors in the develo

217 etworks; and (iii) facilitate the review and dissemination of networks.

218 between EMT and non-EMT cells that promotes dissemination of non-EMT cells.

219 ormed a nonpermissive OV barrier, preventing dissemination of oHSV-1 in the glioma mass.

220 f resuscitation training of Danish citizens, dissemination of on-site AEDs, foundation of an AED regi

221 Similar mechanisms may promote dissemination of other Fn-binding pathogens.

222 lm-relevant amounts of Pf phage prevents the dissemination of P. aeruginosa from the lung.

223 s and rapid recurrence because of widespread dissemination of peritoneal metastases at diagnosis.

224 The ability to promote dissemination of Ras(V12)-induced tumours was shared by

225 acilitate parasite egress and the consequent dissemination of released merozoites throughout the bloo

226 Arguably, the dissemination of science communication has recently ente

227 cience, and indicate a source of bias in the dissemination of scientific findings to broader society.

228 se-transcribed vDNA circles and the systemic dissemination of small-RNA-containing exosomes.

229 construct the molecular evolution and global dissemination of ST8, including USA300.

230 quasi-reproducible approach facilitates the dissemination of statistical methods and codes to indepe

231 ransparency for critical evaluation, further dissemination of study methods, and expedite the exchang

232 ociated with extensive necrosis and systemic dissemination of the bacteria.

233 ing research in this area but also increased dissemination of the existing programs and knowledge.

234 ntain KSHV latency, enhance angiogenesis and dissemination of the infected cells, and interfere with

235 IncX4 plasmids are associated with the dissemination of the mcr-1 genes in Enterobacteriaceae.

236 d/or blood and that levels decline after the dissemination of the organism to extracutaneous sites in

237 infected clot can contribute to the systemic dissemination of the pathogen.

238 t of the study; and fully participate in the dissemination of the study results.

239 palette of compatible labels, allowing rapid dissemination of the technique.

240 but to date their exact contribution to the dissemination of the TLR response is unknown.

241 en-farm biosecurity in preventing widespread dissemination of the virus.

242 We hope that recognition and dissemination of these results will shape the future dir

243 hibits both tumor growth and intraperitoneal dissemination of tumor cells in vivo.

244 cell models and the invasive and metastatic dissemination of tumor cells in vivo.

245 r-related deaths, is enabled by hematogenous dissemination of tumor cells via the circulation.

246 tasis function, the hallmark of hematogenous dissemination of tumor cells.

247 expression in mouse NK cells controlled the dissemination of tumors expressing PDGF-DD more effectiv

248 ndritic cells were sufficient to control the dissemination of virus in an in vitro assay.

249 ency caused by ORF7 deletion results in poor dissemination of VZV among neuronal cells.

250 itial niche for subsequent vascular systemic dissemination of Xcc in distant plant tissues.

251 r, however, the mechanism of trans-placental dissemination of ZIKV remains unknown.

252 Our results document the dissipation and dissemination off farm of ARGs under Finnish limited ant

253 it has been difficult to discern patterns of dissemination owing to the limited number of patients an

254 Surprisingly, both Stxs exhibited similar dissemination patterns and accumulated in the kidneys.

255 ring of EMRSA-15, consistent with widespread dissemination prior to the sampling decade followed by l

256 oth EMT-dependent and EMT-independent cancer dissemination programs.

257 terreus infections are associated with high dissemination rates and poor response to antifungal trea

258 atment and could be responsible for its high dissemination rates.

259 yet the molecular effectors underlying tumor dissemination remain poorly defined.

260 Although there are several potential dissemination scenarios to describe an attack with a bio

261 than being simply agents of transmission and dissemination, spores directly contribute to the establi

262 nd morphology but are redundant for lymphoma dissemination, suggesting that targeting both GTPases co

263 ve role in solid tumor growth and metastatic dissemination than simply providing the physical structu

264 se results demonstrate that after metastatic dissemination, the microenvironment provides signals to

265 the biggest changes are concerned with data dissemination: the web frontend has been completely rede

266 iveness and inform future implementation and dissemination, this Special Communication emphasizes met

267 cts of SNS signalling to prevent tumour cell dissemination through lymphatic routes may provide a str

268 hat loss of VHL could be driving tumour cell dissemination through stabilization of HIF-1alpha in RCC

269 eased kidney abscess formation and bacterial dissemination throughout kidney tissue at early times po

270 rates into the kidney and enhanced bacterial dissemination throughout kidney tissue.

271 und to be important for effective spirochete dissemination to deep tissues for as long as 3 weeks pos

272 r studies confirm a role of Akt2 in CRC cell dissemination to distant organs in vivo.

273 severely attenuated in murine infection and dissemination to distant tissues after needle inoculatio

274 The infectious dose that led to consistent dissemination to kidney after conjunctival infection was

275 ight caudal lung lobe, with no or reduced TB dissemination to other lobes, spleen, or liver/kidney; i

276 K. pneumoniae burden in the blood or prevent dissemination to other organs.

277 ce and inversely correlating with tumor cell dissemination to regional lymph nodes, suggesting that H

278 f IFN-gamma-deficient mice promoted parasite dissemination to secondary sites, reproducing the LgyLRV

279 yngeal lymphoid tissues, rapidly followed by dissemination to systemic lymphoid tissues without evide

280 haryngeal lymphoid tissues followed by rapid dissemination to systemic lymphoid tissues.

281 ce suffered dramatically increased bacterial dissemination to the bloodstream.

282 g acute toxoplasmosis in the mouse, reducing dissemination to the central nervous system, and decreas

283 which can cross tissue barriers, assist ZIKV dissemination to the fetus.

284 monia, and its absence resulted in bacterial dissemination to the liver and hepatic necrosis.

285 d greater bacterial burdens with evidence of dissemination to the liver and spleen but ultimately cle

286 been proposed as a necessary step for virus dissemination via draining lymph nodes and blood.

287 esting a potential mechanism for spirochetal dissemination via IDO1-mediated localized immunosuppress

288 hat is resistant to tetherin but that virion dissemination via plasma is inhibited by tetherin and is

289 Bacterial dissemination via the cardiovascular system is the most

290 Bacteremia with hematogenous dissemination was first detected 2 days after exposure.

291 An animal model of peritoneal dissemination was used to assess the oncogenic role of t

292 s from 7 ocular oncology centers who died of dissemination were analyzed.

293 Thus, we posit that, during metastatic dissemination (when cancer cells are exposed to periods

294 propose here a microscopic model of culture dissemination which takes into account that, in real soc

295 athways used by S100A4 to promote metastatic dissemination, with potential prognostic and therapeutic

296 ter baumannii, is necessary to prevent their dissemination within health care settings.

297 eriaceae (CPE) is essential to prevent their dissemination within health care settings.

298 e for the lack of Siglec-1 in fuelling HIV-1 dissemination within infected individuals.

299 outbreaks, much less is understood about its dissemination within the body.

300 nfection and disease, aiding replication and dissemination within the host.